Advanced search
Publication Cover
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration Volume 20, 2019 - Issue 7-8
Submit an article Journal homepage
4,146
Views
31
CrossRef citations to date
0
Altmetric
Clinical

Loss of appetite is associated with a loss of weight and fat mass in patients with amyotrophic lateral sclerosis

Shyuan T. NgoAustralian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, Australia, ;Queensland Brain Institute, The University of Queensland, Brisbane, Australia, ;Centre for Clinical Research, The University of Queensland, Brisbane, Australia, ;Department of Neurology, Royal Brisbane and Women’s Hospital, Brisbane, Australia, ;Wesley Medical Research, The Wesley Hospital, Brisbane, Australia, View further author information
,
Ruben P.A. van EijkDepartment of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands, ;Biostatistics & Research Support, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands, and View further author information
,
V. ChachaySchool of Human Movement and Nutrition Sciences, The University of Queensland, Brisbane, AustraliaView further author information
,
Leonard H. van den BergDepartment of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands, View further author information
,
Pamela A. McCombeCentre for Clinical Research, The University of Queensland, Brisbane, Australia, ;Department of Neurology, Royal Brisbane and Women’s Hospital, Brisbane, Australia, ;Wesley Medical Research, The Wesley Hospital, Brisbane, Australia, View further author information
,
Robert D. HendersonQueensland Brain Institute, The University of Queensland, Brisbane, Australia, ;Centre for Clinical Research, The University of Queensland, Brisbane, Australia, ;Department of Neurology, Royal Brisbane and Women’s Hospital, Brisbane, Australia, ;Wesley Medical Research, The Wesley Hospital, Brisbane, Australia, View further author information
&
Frederik J. SteynAustralian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, Australia, ;Centre for Clinical Research, The University of Queensland, Brisbane, Australia, ;Department of Neurology, Royal Brisbane and Women’s Hospital, Brisbane, Australia, ;Wesley Medical Research, The Wesley Hospital, Brisbane, Australia, Correspondence[email protected]
View further author information
 show all
Pages 497-505 | Received 21 Feb 2019, Accepted 13 May 2019, Published online: 30 May 2019

Citations (31)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (4)

Remko M. Van Eenennaam, Willeke J. Kruithof, Esther T. Kruitwagen-Van Reenen, Leonard H. van den Berg, Johanna M.A. Visser-Meily & Anita Beelen. (2022) Current practices and barriers in gastrostomy indication in amyotrophic lateral sclerosis: a survey of ALS care teams in The Netherlands. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 23:3-4, pages 242-251.
Read now
Cory J. Holdom, Shyuan T. Ngo, Pamela A. McCombe, Robert D. Henderson & Frederik J. Steyn. (2022) Low plasma hyaluronan is associated with faster functional decline in patients with amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 23:1-2, pages 42-48.
Read now
Adriano Chiò, Antonio Canosa, Andrea Calvo, Cristina Moglia, Alessandro Cicolin & Gabriele Mora. (2021) Developments in the assessment of non-motor disease progression in amyotrophic lateral sclerosis. Expert Review of Neurotherapeutics 21:12, pages 1419-1440.
Read now
Shyuan T. Ngo, Restuadi Restuadi, Allan F. McCrae, Ruben P. Van Eijk, Fleur Garton, Robert D. Henderson, Naomi R. Wray, Pamela A. McCombe & Frederik J. Steyn. (2020) Progression and survival of patients with motor neuron disease relative to their fecal microbiota. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 21:7-8, pages 549-562.
Read now

Articles from other publishers (27)

Stephanie L. Howe, Cory J. Holdom, Pamela A. McCombe, Robert D. Henderson, Jeffrey M. Zigman, Shyuan T. Ngo & Frederik J. Steyn. (2023) Associations of postprandial ghrelin, liver‐expressed antimicrobial peptide 2 and leptin levels with body composition, disease progression and survival in patients with amyotrophic lateral sclerosis. European Journal of Neurology.
Crossref
Albert Ludolph, Luc Dupuis, Edward Kasarskis, Frederik Steyn, Shyuan Ngo & Christopher McDermott. (2023) Nutritional and metabolic factors in amyotrophic lateral sclerosis. Nature Reviews Neurology 19:9, pages 511-524.
Crossref
Thibaut Burg & Ludo Van Den Bosch. (2023) Abnormal energy metabolism in ALS: a key player?. Current Opinion in Neurology 36:4, pages 338-345.
Crossref
Matei Bolborea, Pauline Vercruysse, Tselmen Daria, Johanna C. Reiners, Najwa Ouali Alami, Simon J. Guillot, Stéphane Dieterlé, Jérôme Sinniger, Jelena Scekic-Zahirovic, Amela Londo, Hippolyte Arcay, Marc-Antoine Goy, Claudia Nelson de Tapia, Dietmar R. Thal, Kazumoto Shibuya, Ryo Otani, Kimihito Arai, Satoshi Kuwabara, Albert C. Ludolph, Francesco Roselli, Deniz Yilmazer-Hanke & Luc Dupuis. (2023) Loss of hypothalamic MCH decreases food intake in amyotrophic lateral sclerosis. Acta Neuropathologica 145:6, pages 773-791.
Crossref
Katarina Maksimovic, Mohieldin Youssef, Justin You, Hoon-Ki Sung & Jeehye Park. (2023) Evidence of Metabolic Dysfunction in Amyotrophic Lateral Sclerosis (ALS) Patients and Animal Models. Biomolecules 13:5, pages 863.
Crossref
Jeryn Chang, Thomas B. Shaw, Cory J. Holdom, Pamela A. McCombe, Robert D. Henderson, Jurgen Fripp, Markus Barth, Christine C. Guo, Shyuan T. Ngo & Frederik J. Steyn. (2022) Lower hypothalamic volume with lower body mass index is associated with shorter survival in patients with amyotrophic lateral sclerosis. European Journal of Neurology 30:1, pages 57-68.
Crossref
Zoe Castles, Lauren Buckett, Leanne Jiang, Frederik J. Steyn & Shyuan T. Ngo. 2023. Diet and Nutrition in Neurological Disorders. Diet and Nutrition in Neurological Disorders 123 140 .
Max Sarmet, Aamna Kabani, Nicholas J. Maragakis & Ambereen K. Mehta. (2022) Appetite and quality of life in amyotrophic lateral sclerosis: A scoping review. Muscle & Nerve 66:6, pages 653-660.
Crossref
Jin-Yue Li, Xiao-Han Sun, Zheng-Yi Cai, Dong-chao Shen, Xun-Zhe Yang, Ming-Sheng Liu & Li-Ying Cui. (2022) Correlation of weight and body composition with disease progression rate in patients with amyotrophic lateral sclerosis. Scientific Reports 12:1.
Crossref
Annalisa Chiavaroli, Viviana di Giacomo, Barbara De Filippis, Amelia Cataldi, Claudio Ferrante & Letizia Giampietro. (2022) The Small Molecule PPARγ Agonist GL516 Induces Feeding-Stimulatory Effects in Hypothalamus Cells Hypo-E22 and Isolated Hypothalami. Molecules 27:15, pages 4882.
Crossref
Andrew T. Nelson & Davide Trotti. (2022) Altered Bioenergetics and Metabolic Homeostasis in Amyotrophic Lateral Sclerosis. Neurotherapeutics 19:4, pages 1102-1118.
Crossref
Johannes Dorst, Judith Doenz, Katharina Kandler, Jens Dreyhaupt, Hayrettin Tumani, Simon Witzel, Joachim Schuster & Albert C Ludolph. (2022) Fat-rich versus carbohydrate-rich nutrition in ALS: a randomised controlled study. Journal of Neurology, Neurosurgery & Psychiatry 93:3, pages 298-302.
Crossref
Cory J. Holdom, Frederik J. Steyn, Robert D. Henderson, Pamela A. McCombe, Mary-Louise Rogers & Shyuan T. Ngo. 2022. Neurodegenerative Diseases Biomarkers. Neurodegenerative Diseases Biomarkers 263 306 .
Sean White, Nicolò Zarotti, Daniel Beever, Mike Bradburn, Paul Norman, Elizabeth Coates, Theocharis Stavroulakis, David White, Alexander McGeachan, Isobel Williams, Gemma Hackney, Vanessa Halliday & Christopher McDermott. (2021) The nutritional management of people living with amyotrophic lateral sclerosis: A national survey of dietitians. Journal of Human Nutrition and Dietetics 34:6, pages 1064-1071.
Crossref
Germana Cocozza, Stefano Garofalo, Marta Morotti, Giuseppina Chece, Alfonso Grimaldi, Mario Lecce, Ferdinando Scavizzi, Rossella Menghini, Viviana Casagrande, Massimo Federici, Marcello Raspa, Heike Wulff & Cristina Limatola. (2021) The feeding behaviour of Amyotrophic Lateral Sclerosis mouse models is modulated by the Ca 2+ ‐activated K Ca 3.1 channels . British Journal of Pharmacology 178:24, pages 4891-4906.
Crossref
Cory J. Holdom, Mark R. Janse van Mantgem, Ruben P. A. van Eijk, Stephanie L. Howe, Leonard H. van den Berg, Pamela A. McCombe, Robert D. Henderson, Shyuan T. Ngo & Frederik J. Steyn. (2021) Venous creatinine as a biomarker for loss of fat‐free mass and disease progression in patients with amyotrophic lateral sclerosis. European Journal of Neurology 28:11, pages 3615-3625.
Crossref
Simon J. Guillot, Matei Bolborea & Luc Dupuis. (2021) Dysregulation of energy homeostasis in amyotrophic lateral sclerosis. Current Opinion in Neurology 34:5, pages 773-780.
Crossref
Shyuan T. Ngo, Hao Wang, Robert D. Henderson, Cyril Bowers & Frederik J. Steyn. (2021) Ghrelin as a treatment for amyotrophic lateral sclerosis. Journal of Neuroendocrinology 33:7.
Crossref
Yajun Wang, Shan Ye, Lu Chen, Lu Tang & Dongsheng Fan. (2021) Loss of appetite in patients with amyotrophic lateral sclerosis is associated with weight loss and anxiety/depression. Scientific Reports 11:1.
Crossref
T.J. Tracey, S.E. Kirk, F.J. Steyn & S.T. Ngo. (2021) The role of lipids in the central nervous system and their pathological implications in amyotrophic lateral sclerosis. Seminars in Cell & Developmental Biology 112, pages 69-81.
Crossref
Rebekah M. Ahmed, Frederik Steyn & Luc Dupuis. 2021. The Human Hypothalamus - Middle and Posterior Region. The Human Hypothalamus - Middle and Posterior Region 327 338 .
J. Sun, J. J. Carrero, U. Zagai, M. Evans, C. Ingre, Y. Pawitan & F. Fang. (2020) Blood biomarkers and prognosis of amyotrophic lateral sclerosis. European Journal of Neurology 27:11, pages 2125-2133.
Crossref
Alfredo Iacoangeli, Tian Lin, Ahmad Al Khleifat, Ashley R. Jones, Sarah Opie-Martin, Jonathan R.I. Coleman, Aleksey Shatunov, William Sproviero, Kelly L. Williams, Fleur Garton, Restuadi Restuadi, Anjali K. Henders, Karen A. Mather, Merilee Needham, Susan Mathers, Garth A. Nicholson, Dominic B. Rowe, Robert Henderson, Pamela A. McCombe, Roger Pamphlett, Ian P. Blair, David Schultz, Perminder S. Sachdev, Stephen J. Newhouse, Petroula Proitsi, Isabella Fogh, Shyuan T. Ngo, Richard J.B. Dobson, Naomi R. Wray, Frederik J. Steyn & Ammar Al-Chalabi. (2020) Genome-wide Meta-analysis Finds the ACSL5-ZDHHC6 Locus Is Associated with ALS and Links Weight Loss to the Disease Genetics. Cell Reports 33:4, pages 108323.
Crossref
Mark R Janse van Mantgem, Ruben P A van Eijk, Hannelore K van der Burgh, Harold H G Tan, Henk-Jan Westeneng, Michael A van Es, Jan H Veldink & Leonard H van den Berg. (2020) Prognostic value of weight loss in patients with amyotrophic lateral sclerosis: a population-based study. Journal of Neurology, Neurosurgery & Psychiatry 91:8, pages 867-875.
Crossref
B. Kuraszkiewicz, H. Goszczyńska, T. Podsiadły-Marczykowska, M. Piotrkiewicz, P. Andersen, M. Gromicho, J. Grosskreutz, M. Kuźma-Kozakiewicz, S. Petri, B. Stubbendorf, K. Szacka, H. Uysal & M. de Carvalho. (2020) Potential Preventive Strategies for Amyotrophic Lateral Sclerosis. Frontiers in Neuroscience 14.
Crossref
Taylor Mezoian, Emily Belt, Jamie Garry, Jane Hubbard, Christopher T. Breen, Leah Miller, Mark Levine‐Weinberg, Paige Nalipinski, Stacey Sullivan, James Chan & Anne‐Marie Wills. (2019) Loss of appetite in amyotrophic lateral sclerosis is associated with weight loss and decreased calorie consumption independent of dysphagia. Muscle & Nerve 61:2, pages 230-234.
Crossref
Christine Germeys, Tijs Vandoorne, Valérie Bercier & Ludo Van Den Bosch. (2019) Existing and Emerging Metabolomic Tools for ALS Research. Genes 10:12, pages 1011.
Crossref

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.