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Evidence-Based Toxicology Volume 1, 2023 - Issue 1
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Research Article

Protocol for designing INVITES-IN, a tool for assessing the internal validity of in vitro studies

Camilla Svendsena Norwegian Scientific Committee for Food and Environment, Norwegian Institute of Public Health, Oslo, Norway;b Department of Chemical Toxicology, Norwegian Institute of Public Health, Oslo, NorwayORCID Iconhttps://orcid.org/0000-0002-3216-0469View further author information
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Paul Whaleya Norwegian Scientific Committee for Food and Environment, Norwegian Institute of Public Health, Oslo, Norway;c Lancaster Environment Centre, Lancaster University, Lancaster, UKORCID Iconhttps://orcid.org/0000-0003-4021-0785View further author information
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Gunn E. Vista Norwegian Scientific Committee for Food and Environment, Norwegian Institute of Public Health, Oslo, Norway;d Division for Health Services, Norwegian Institute of Public Health, Oslo, NorwayView further author information
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Trine Husøya Norwegian Scientific Committee for Food and Environment, Norwegian Institute of Public Health, Oslo, Norway;e Department of Food Safety, Norwegian Institute of Public Health, Oslo, NorwayORCID Iconhttps://orcid.org/0000-0002-2827-7111View further author information
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Anna Beroniusf Institute of Environmental Medicine, Karolinska Institutet, Stockholm, SwedenORCID Iconhttps://orcid.org/0000-0001-9494-5395View further author information
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Emma Di Consigliog Environment & Health Department, Italian National Institute of Health (ISS), Rome, ItalyORCID Iconhttps://orcid.org/0000-0001-5575-0376View further author information
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Ingrid Druweh United States Environmental Protection Agency, Office of Research and Development, Center for Public Health and Environmental Assessments, Research Triangle Park, NC, USAORCID Iconhttps://orcid.org/0000-0002-0591-0295View further author information
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Thomas Hartungi Center for Alternatives to Animal Testing (CAAT), Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD, USA;j CAAT Europe, University of Konstanz, Konstanz, GermanyORCID Iconhttps://orcid.org/0000-0003-1359-7689View further author information
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Vasiliki I. Hatzik Laboratory of Toxicological Control of Pesticides, Scientific Directorate of Pesticides’ Control and Phytopharmacy, Benaki Phytopathological Institute, Kifissia, GreeceORCID Iconhttps://orcid.org/0000-0001-8165-9242View further author information
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Sebastian Hoffmannl Evidence-Based Toxicology Collaboration (EBTC), Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD, USA;m SEH consulting + services, Paderborn, GermanyORCID Iconhttps://orcid.org/0000-0002-3214-7678View further author information
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Carlijn R. Hooijmansn Department of Anesthesiology, Pain and Palliative Care, Radboud University Medical Centre, Nijmegen, NetherlandsORCID Iconhttps://orcid.org/0000-0001-6435-5714View further author information
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Kyriaki Macherak Laboratory of Toxicological Control of Pesticides, Scientific Directorate of Pesticides’ Control and Phytopharmacy, Benaki Phytopathological Institute, Kifissia, GreeceORCID Iconhttps://orcid.org/0000-0001-6499-3468View further author information
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Joshua F. Robinsono Department of Obstetrics, Gynecology & Reproductive Sciences, University of California, San Francisco (UCSF), CA, USAORCID Iconhttps://orcid.org/0000-0002-2421-4535View further author information
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Erwin Roggenp 3Rs Management and Consulting ApS, Lyngby, DenmarkORCID Iconhttps://orcid.org/0000-0002-9371-8390View further author information
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Andrew A. Rooneyq Division of Translational Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USAORCID Iconhttps://orcid.org/0000-0002-1756-5185View further author information
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Nicolas Rothr Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland;s Swiss Centre for Applied Human Toxicology (SCAHT), Basel, SwitzerlandORCID Iconhttps://orcid.org/0000-0002-2917-4384View further author information
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Eliana Spiliotik Laboratory of Toxicological Control of Pesticides, Scientific Directorate of Pesticides’ Control and Phytopharmacy, Benaki Phytopathological Institute, Kifissia, GreeceORCID Iconhttps://orcid.org/0000-0002-0441-7466View further author information
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Anastasia Spyropoulouk Laboratory of Toxicological Control of Pesticides, Scientific Directorate of Pesticides’ Control and Phytopharmacy, Benaki Phytopathological Institute, Kifissia, GreeceORCID Iconhttps://orcid.org/0000-0001-8599-7740View further author information
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Olga Tcheremenskaiag Environment & Health Department, Italian National Institute of Health (ISS), Rome, ItalyORCID Iconhttps://orcid.org/0000-0002-5029-3484View further author information
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Emanuela Testaig Environment & Health Department, Italian National Institute of Health (ISS), Rome, ItalyORCID Iconhttps://orcid.org/0000-0003-3113-5103View further author information
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Mathieu Vinkent Department of Pharmaceutical and Pharmacological Sciences, Vrije Universiteit Brussel, Brussel, BelgiumORCID Iconhttps://orcid.org/0000-0001-5115-8893View further author information
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Gro H. Mathisena Norwegian Scientific Committee for Food and Environment, Norwegian Institute of Public Health, Oslo, NorwayCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-3824-4898View further author information
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Article: 2232415 | Received 09 Mar 2023, Accepted 19 Jun 2023, Published online: 31 Aug 2023

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Gro H. Mathisen, Gunn E. Vist, Paul Whaley, Richard A. White, Trine Husøy, Heather M. Ames, Anna Beronius, Emma Di Consiglio, Ingrid Druwe, Thomas Hartung, Sebastian Hoffmann, Carlijn R. Hooijmans, Kyriaki Machera, Pilar Prieto, Joshua F. Robinson, Erwin Roggen, Andrew A. Rooney, Nicolas Roth, Eliana Spilioti, Anastasia Spyropoulou, Olga Tcheremenskaia, Emanuela Testai, Mathieu Vinken & Camilla Svendsen. (2023) Protocol: Testing the Performance of INVITES-IN, A Tool for Assessing the Internal Validity of In Vitro Studies. Evidence-Based Toxicology 1:1.
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