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Journal Of Herbal Pharmacotherapy Volume 5, 2005 - Issue 3
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Original Article

Differential Activity of Lipoic Acid Enantiomers in Cell Culture

Jerry Robert Smith Department of Biomedical and Pharmaceutical Sciences, COBRE Center for Functional and Structural Neuroscience, School of Pharmacy and Allied Health Sciences, The University of Montana, Missoula, MT, 59812-1552, USACorrespondence[email protected]
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,
Harish V. Thiagaraj Department of Biomedical and Pharmaceutical Sciences, COBRE Center for Functional and Structural Neuroscience, School of Pharmacy and Allied Health Sciences, The University of Montana, Missoula, MT, 59812-1552, USA
,
Benjamin Seaver Department of Biomedical and Pharmaceutical Sciences, COBRE Center for Functional and Structural Neuroscience, School of Pharmacy and Allied Health Sciences, The University of Montana, Missoula, MT, 59812-1552, USA
&
Keith K. Parker Department of Biomedical and Pharmaceutical Sciences, COBRE Center for Functional and Structural Neuroscience, School of Pharmacy and Allied Health Sciences, The University of Montana, Missoula, MT, 59812-1552, USA
Pages 43-54 | Published online: 24 Aug 2009

Citations (10)

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Read on this site (2)

Nan Xia, Tian Liu, Qiang Wang, Qiang Xia & Xiaoli Bian. (2017) In vitro evaluation of α-lipoic acid-loaded lipid nanocapsules for topical delivery. Journal of Microencapsulation 34:6, pages 571-581.
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Sherif Ibrahim, Dayuan Gao & PatrickJ. Sinko. (2014) Selective Cytotoxicity and Combined Effects of Camptothecin or Paclitaxel with Sodium-R-Alpha Lipoate on A549 Human Non-Small Cell Lung Cancer Cells. Nutrition and Cancer 66:3, pages 492-499.
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Articles from other publishers (8)

Michelle Cameron, Cassidy Taylor, Jodi Lapidus, Katrina Ramsey, Dennis Koop & Rebecca Spain. (2020) Gastrointestinal Tolerability and Absorption of R‐ Versus R,S‐ Lipoic Acid in Progressive Multiple Sclerosis: A Randomized Crossover Trial . The Journal of Clinical Pharmacology 60:8, pages 1099-1106.
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Sylvia Hiller, Robert DeKroon, Eric D. Hamlett, Longquan Xu, Cristina Osorio, Jennifer Robinette, Witold Winnik, Stephen Simington, Nobuyo Maeda, Oscar Alzate & Xianwen Yi. (2016) Alpha-lipoic acid supplementation protects enzymes from damage by nitrosative and oxidative stress. Biochimica et Biophysica Acta (BBA) - General Subjects 1860:1, pages 36-45.
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Shimaa Omar Ali, Hebatallah Abd El-moeti Darwish & Nabila Abd El-fattah Ismail. (2014) Modulatory effects of curcumin, silybin-phytosome and alpha-R-lipoic acid against thioacetamide-induced liver cirrhosis in rats. Chemico-Biological Interactions 216, pages 26-33.
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Daniele Tomassoni, Francesco Amenta, Consuelo Amantini, Valerio Farfariello, Lorenzo Di Cesare Mannelli, Innocent Nwankwo, Carlotta Marini & Seyed Tayebati. (2013) Brain Activity of Thioctic Acid Enantiomers: In Vitro and in Vivo Studies in an Animal Model of Cerebrovascular Injury. International Journal of Molecular Sciences 14:3, pages 4580-4595.
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Takashi Ide, Ayana Azechi, Natsuko Suzuki, Yoko Kunimatsu, Chihiro Nakajima & Sayaka Kitade. (2013) Effects of dietary α-lipoic acid enantiomers on hepatic fatty acid metabolism in rats. Journal of Functional Foods 5:1, pages 71-79.
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Masao Yamasaki, Masahiro Iwase, Kazuo Kawano, Yoichi Sakakibara, Masahito Suiko & Kazuo Nishiyama. (2012) Alpha lipoic acid selectively inhibits proliferation and adhesion to fibronectin of v-H-ras-transformed 3Y1 cells. Journal of Clinical Biochemistry and Nutrition 50:3, pages 234-240.
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Sonemany Salinthone, Robynn V. Schillace, Catherine Tsang, John W. Regan, Dennis N. Bourdette & Daniel W. Carr. (2011) Lipoic acid stimulates cAMP production via G protein-coupled receptor-dependent and -independent mechanisms. The Journal of Nutritional Biochemistry 22:7, pages 681-690.
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Giorgia Melli, Michela Taiana, Francesca Camozzi, Daniela Triolo, Paola Podini, Angelo Quattrini, Franco Taroni & Giuseppe Lauria. (2008) Alpha-lipoic acid prevents mitochondrial damage and neurotoxicity in experimental chemotherapy neuropathy. Experimental Neurology 214:2, pages 276-284.
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