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Journal Of Herbal Pharmacotherapy Volume 5, 2005 - Issue 4
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Original Article

Urtica dioicafor Treatment of Benign Prostatic Hyperplasia

A Prospective, Randomized, Double-Blind, Placebo-Controlled, Crossover Study

Mohammad Reza Safarinejad Department of Urology, Urology Nephrology Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran; Department of Urology, Urology Nephrology Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, IranCorrespondence[email protected]
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(Assistant Professor of Urology, Associate Editor of Urology Journal)
Pages 1-11 | Published online: 24 Aug 2009

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Yan-Liang Wang, Li Li, Xiao-Chen Cheng, Yu-Xin Lu & Qing-Lin Zhang. (2012) Structure of a polysaccharide from Urtica fissa determined by NMR spectra. Journal of Asian Natural Products Research 14:6, pages 592-595.
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Yan Li, Yan-Liang Wang, Li Li, Liu Liu, Yu-Xin Lu, Xiao-Chen Cheng & Qing-Lin Zhang. (2009) Structural characterization of polysaccharides from the roots of Urtica fissa . Journal of Asian Natural Products Research 11:11, pages 951-957.
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Articles from other publishers (60)

Prabhakar Semwal, Abdur Rauf, Ahmed Olatunde, Pooja Singh, Mohamed Y. Zaky, Md. Mozahidul Islam, Anees Ahmed Khalil, Abdullah S. M. Aljohani, Waleed Al Abdulmonem & Giovanni Ribaudo. (2023) The medicinal chemistry of Urtica dioica L.: from preliminary evidence to clinical studies supporting its neuroprotective activity. Natural Products and Bioprospecting 13:1.
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Kendal L. Stewart & Edwin D. Lephart. (2023) Overview of BPH: Symptom Relief with Dietary Polyphenols, Vitamins and Phytochemicals by Nutraceutical Supplements with Implications to the Prostate Microbiome. International Journal of Molecular Sciences 24:6, pages 5486.
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Vaki Antoniou, Vineet Gauhar, Sachin Modi & Bhaskar Kumar Somani. (2023) Role of Phytotherapy in the Management of BPH: A Summary of the Literature. Journal of Clinical Medicine 12:5, pages 1899.
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Manish Pathak, Rupesh Kumar Pandey, Lubhan Singh, Amit Kumar, Ganesh Prasad Mishra, Ravindra Kumar Pandey, Bina Gidwani & Shiv Shankar Shukla. 2023. Herbal Medicine Phytochemistry. Herbal Medicine Phytochemistry 1 24 .
Denis V. Krakhotkin, Volodymyr A. Chernylovskyi, Ruslan A. Bugaev & Dmitry N. Pikhovkin. (2022) A Prospective, Observational Study of Use Combination Silodosin 8 mg Plus Serenoa Repens, Urtica Dioica, Cucurbita Pepo (Rotaprost) Compared With Silodosin 8 mg Alone in Treatment Patients with Benign Prostate Hyperplasia. Clinical Complementary Medicine and Pharmacology 2:3, pages 100043.
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Ilaria Marotti, Elettra Frassineti, Grazia Trebbi, Mattia Alpi, Eros D’Amen & Giovanni Dinelli. (2022) Health-promoting phytochemicals of stinging nettle (Urtica dioica L.) grown under organic farming in Italian environments. Industrial Crops and Products 182, pages 114903.
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Nicole T. Eise, Jamie S. Simpson, Philip E. Thompson & Sabatino Ventura. (2022) Aqueous extracts of Urtica dioica (stinging nettle) leaf contain a P2-purinoceptor antagonist—Implications for male fertility. PLOS ONE 17:7, pages e0271735.
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Asieh Khalafi-Kheydani, Hosein Mahmoodi, Zohreh Sadat & Ismail Azizi-Fini. (2022) The effect of nettle root extract on urinary problems in older men with benign prostatic hyperplasia: A randomized clinical trial. Journal of Herbal Medicine 34, pages 100568.
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Jean M. Bokelmann. 2022. Medicinal Herbs in Primary Care. Medicinal Herbs in Primary Care 599 607 .
Eszter Csikós, Adrienn Horváth, Kamilla Ács, Nóra Papp, Viktória Lilla Balázs, Marija Sollner Dolenc, Maša Kenda, Nina Kočevar Glavač, Milan Nagy, Michele Protti, Laura Mercolini, Györgyi Horváth & Ágnes Farkas. (2021) Treatment of Benign Prostatic Hyperplasia by Natural Drugs. Molecules 26:23, pages 7141.
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Ihor Gorpynchenko, Yurii Gurzhenko & Volodymyr Spyrydonenko. (2021) Analysis of the Effectiveness of Various Types of Conservative Therapy for Chronic Bacterial Prostatitis. Health of Man:3, pages 35-48.
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Anurag Kumar Singh, Sachchida Nand Rai, Anand Maurya, Gaurav Mishra, Rajendra Awasthi, Anshul Shakya, Dinesh Kumar Chellappan, Kamal Dua, Emanuel Vamanu, Sushil Kumar Chaudhary & M. P. Singh. (2021) Therapeutic Potential of Phytoconstituents in Management of Alzheimer’s Disease. Evidence-Based Complementary and Alternative Medicine 2021, pages 1-19.
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Stephen J Smith, Adrian L Lopresti, Shaun Y M Teo & Timothy J Fairchild. (2021) Examining the Effects of Herbs on Testosterone Concentrations in Men: A Systematic Review. Advances in Nutrition 12:3, pages 744-765.
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Kristian Leisegang. 2021. Herbal Medicine in Andrology. Herbal Medicine in Andrology 165 173 .
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Marco Dacrema, Eduardo Sommella, Cristina Santarcangelo, Beatrice Bruno, Maria Grazia Marano, Violetta Insolia, Anella Saviano, Pietro Campiglia, Mariano Stornaiuolo & Maria Daglia. (2020) Metabolic profiling, in vitro bioaccessibility and in vivo bioavailability of a commercial bioactive Epilobium angustifolium L. extract. Biomedicine & Pharmacotherapy 131, pages 110670.
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Mohaddese Mahboubi. (2020) Urtica dioica in the Management of Benign Prostate Hyperplasia (BPH). The Natural Products Journal 10:5, pages 535-542.
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Malte Rieken, Alexander Müller, Hans-Peter Schmid, Thomas Bschleipfer, Stephen Wyler & Hubert John. (2020) Stellenwert der Phytotherapeutika in der Therapie von MiktionsbeschwerdenRôle des produits phytothérapeutiques dans le traitement des troubles mictionnels. Urologie in der Praxis 22:3, pages 80-85.
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Steven P Hirsh, Marianne Pons, Steven V Joyal & Andrew G Swick. (2020) Self-Assessed Benefits of a Prostate Health Formulation on Nocturia in Healthy Males With Mild Lower Urinary Tract Symptoms: An Open Label Study. Global Advances in Health and Medicine 9, pages 216495612097363.
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Zhongjuan Wang, Yanhua Li, Chongjing Wang, Hongying Xia, Yueqin Liang & Zhongkun Li. (2019) Oral administration of Urtica�macrorrhiza Hand.‑Mazz. polysaccharides to protect against cyclophosphamide‑induced intestinal immunosuppression. Experimental and Therapeutic Medicine.
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Mustafa Tutal. (2019) Medikamentöse Therapie des benignen Prostatasyndroms – Chemie oder PflanzenDrug treatment of benign prostate syndrome: chemicals or plants. Urologie in der Praxis 21:1, pages 10-16.
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Kamyar M. Hedayat & Jean-Claude Lapraz. 2019. The Theory of Endobiogeny. The Theory of Endobiogeny 255 266 .
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Mohammad S. Abu-Darwish & Thomas Efferth. (2018) Medicinal Plants from Near East for Cancer Therapy. Frontiers in Pharmacology 9.
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Wesam Kooti, Karo Servatyari, Masoud Behzadifar, Majid Asadi-Samani, Fatemeh Sadeghi, Bijan Nouri & Hadi Zare Marzouni. (2017) Effective Medicinal Plant in Cancer Treatment, Part 2: Review Study. Journal of Evidence-Based Complementary & Alternative Medicine 22:4, pages 982-995.
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Luboslav Stárka & Lucie Kolátorová Sosvorová. (2016) Phytotherapy in the treatment of benign prostatic hyperplasia - present state i Czech Republic. Praktické lékárenství 12:E-verze 6/16, pages e23-e30.
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Ashish Kumar Jena, Karan Vasisht, Neetika Sharma, Ramdeep Kaur, Mamta Sachdeva Dhingra & Maninder Karan. (2016) Amelioration of testosterone induced benign prostatic hyperplasia by Prunus species. Journal of Ethnopharmacology 190, pages 33-45.
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Amal Ait Haj Said, Ibrahim Sbai El Otmani, Sanae Derfoufi & Adnane Benmoussa. (2016) Mise en valeur du potentiel nutritionnel et thérapeutique de l’ortie dioïque (Urtica dioïca L.). Hegel N° 3:3, pages 280-292.
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Matthew Sharp, Kevin Shields, Jacob Rauch, Ryan Lowery, Shane Durkee, Gabriel Wilson & Eduardo De Souza. (2016) The Effects of a Multi-Ingredient Performance Supplement on Hormonal Profiles and Body Composition in Male College Athletes. Sports 4:2, pages 26.
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Majid Asadi-Samani, Wesam Kooti, Elahe Aslani & Hedayatollah Shirzad. (2015) A Systematic Review of Iran’s Medicinal Plants With Anticancer Effects. Journal of Evidence-Based Complementary & Alternative Medicine 21:2, pages 143-153.
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Olta Allkanjari & Annabella Vitalone. (2015) What do we know about phytotherapy of benign prostatic hyperplasia?. Life Sciences 126, pages 42-56.
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Reza Hosseinabadi, Mohammad Heidari, Khatereh Anbari & Yadollah Pournia. (2014) Urtica dioica for treatment of lower urinary tract symptoms associated with benign prostatic hyperplasia . International Journal of Urological Nursing 8:3, pages 114-121.
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Haiying Zhang, Ning Li, Kun Li & Peng Li. (2014) Protective effect of Urtica dioica methanol extract against experimentally induced urinary calculi in rats. Molecular Medicine Reports.
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Daniel Herrmann, Andrea Schreiber, Anna Ciotkowska, Frank Strittmatter, Raphaela Waidelich, Christian G. Stief, Christian Gratzke & Martin Hennenberg. (2014) Honokiol, a constituent of Magnolia species, inhibits adrenergic contraction of human prostate strips and induces stromal cell death. Prostate International 2:3, pages 140-146.
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Ester Pagano, Massimiliano Laudato, Michele Griffo & Raffaele Capasso. (2014) Phytotherapy of Benign Prostatic Hyperplasia. A Minireview. Phytotherapy Research 28:7, pages 949-955.
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Alireza Ghorbanibirgani, Ali Khalili & Laleh Zamani. (2013) The Efficacy of Stinging Nettle (Urtica Dioica) in Patients with Benign Prostatic Hyperplasia: A Randomized Double-Blind Study in 100 Patients. Iranian Red Crescent Medical Journal 15:1.
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