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Other Tissues

Development of Mice with Osteoblast-Specific Connexin43 Gene Deletion

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Pages 445-450 | Published online: 11 Jul 2009

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Elizabeth McLachlan, Janet L. Manias, Xiang-Qun Gong, Crystal S. Lounsbury, Qing Shao, Suzanne M. Bernier, Donglin Bai & Dale W. Laird. (2005) Functional Characterization of Oculodentodigital Dysplasia-Associated Cx43 Mutants. Cell Communication & Adhesion 12:5-6, pages 279-292.
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Articles from other publishers (31)

Lilian I. Plotkin, Iqra AsadAlex E. Kritikos & Natasha Sanz. (2023) Role of Cx43 on the Bone Cell Generation, Function, and Survival. Bioelectricity 5:3, pages 188-195.
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Lilian I. Plotkin, Dale W. Laird & Joelle Amedee. (2016) Role of connexins and pannexins during ontogeny, regeneration, and pathologies of bone. BMC Cell Biology 17:S1.
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Hua Shen, Susan Grimston, Roberto Civitelli & Stavros Thomopoulos. (2015) Deletion of Connexin43 in Osteoblasts/Osteocytes Leads to Impaired Muscle Formation in Mice. Journal of Bone and Mineral Research 30:4, pages 596-605.
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Shane A Lloyd, Alayna E Loiselle, Yue Zhang & Henry J Donahue. (2014) Evidence for the role of connexin 43-mediated intercellular communication in the process of intracortical bone resorption via osteocytic osteolysis. BMC Musculoskeletal Disorders 15:1.
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Shane A Lloyd, Alayna E Loiselle, Yue Zhang & Henry J Donahue. (2014) Shifting Paradigms on the Role of Connexin43 in the Skeletal Response to Mechanical Load. Journal of Bone and Mineral Research 29:2, pages 275-286.
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Mitchell B. Schaffler, Wing-Yee Cheung, Robert Majeska & Oran Kennedy. (2013) Osteocytes: Master Orchestrators of Bone. Calcified Tissue International 94:1, pages 5-24.
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Alayna E. Loiselle, Shane A. J. Lloyd, Emmanuel M. Paul, Gregory S. Lewis & Henry J. Donahue. (2013) Inhibition of GSK-3? Rescues the Impairments in Bone Formation and Mechanical Properties Associated with Fracture Healing in Osteoblast Selective Connexin 43 Deficient Mice. PLoS ONE 8:11, pages e81399.
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Shane A. Lloyd, Alayna E. Loiselle, Yue Zhang & Henry J. Donahue. (2013) Connexin 43 deficiency desensitizes bone to the effects of mechanical unloading through modulation of both arms of bone remodeling. Bone 57:1, pages 76-83.
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Takao Inoue, Man Hagiyama, Eisuke Enoki, Minami A. Sakurai, Akihiro Tan, Tomohiko Wakayama, Shoichi Iseki, Yoshinori Murakami, Kanji Fukuda, Chiaki Hamanishi & Akihiko Ito. (2013) Cell adhesion molecule 1 is a new osteoblastic cell adhesion molecule and a diagnostic marker for osteosarcoma. Life Sciences 92:1, pages 91-99.
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Alayna E. Loiselle, Emmanuel M. Paul, Gregory S. Lewis & Henry J. Donahue. (2012) Osteoblast and osteocyte‐specific loss of Connexin43 results in delayed bone formation and healing during murine fracture healing. Journal of Orthopaedic Research 31:1, pages 147-154.
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Shane A Lloyd, Gregory S Lewis, Yue Zhang, Emmanuel M Paul & Henry J Donahue. (2012) Connexin 43 deficiency attenuates loss of trabecular bone and prevents suppression of cortical bone formation during unloading. Journal of Bone and Mineral Research 27:11, pages 2359-2372.
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Yue Zhang, Emmanuel M. Paul, Vikram Sathyendra, Andrew Davison, Neil Sharkey, Sarah Bronson, Sundar Srinivasan, Ted S. Gross & Henry J. Donahue. (2011) Enhanced Osteoclastic Resorption and Responsiveness to Mechanical Load in Gap Junction Deficient Bone. PLoS ONE 6:8, pages e23516.
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Shane A. J. Lloyd & Henry J. Donahue. (2011) Gap Junctions and Biophysical Regulation of Bone Cells. Clinical Reviews in Bone and Mineral Metabolism 8:4, pages 189-200.
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Elizabeth A. Morgan, Jochen G. Schneider, Timothy E. Baroni, Ozge Uluçkan, Emanuela Heller, Michelle A. Hurchla, Hongju Deng, Desiree Floyd, Andrew Berdy, Julie L. Prior, David Piwnica-Worms, Steven L. Teitelbaum, F. Patrick Ross & Katherine N. Weilbaecher. (2009) Dissection of platelet and myeloid cell defects by conditional targeting of the β3‐integrin subunit. The FASEB Journal 24:4, pages 1117-1127.
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Xin Wang. 2009. Transgenesis Techniques. Transgenesis Techniques 265 273 .
Roberto Civitelli & Henry J. Donahue. 2009. Connexins. Connexins 371 386 .
A. F. Schilling, S. Filke, T. Lange, M. Gebauer, S. Brink, A. Baranowsky, J. Zustin & M. Amling. (2008) Gap junctional communication in human osteoclasts in vitro and in vivo . Journal of Cellular and Molecular Medicine 12:6a, pages 2497-2504.
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Zhongyong Li, Zhiyi Zhou, Danny R. Welch & Henry J. Donahue. (2008) Expressing connexin 43 in breast cancer cells reduces their metastasis to lungs. Clinical & Experimental Metastasis 25:8, pages 893-901.
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Susan K Grimston, Michael D Brodt, Matthew J Silva & Roberto Civitelli. (2008) Attenuated Response to In Vivo Mechanical Loading in Mice With Conditional Osteoblast Ablation of the Connexin43 Gene (Gja1). Journal of Bone and Mineral Research 23:6, pages 879-886.
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Elizabeth McLachlan, Isabelle Plante, Qing Shao, Dan Tong, Gerald M Kidder, Suzanne M Bernier & Dale W Laird. (2008) ODDD-Linked Cx43 Mutants Reduce Endogenous Cx43 Expression and Function in Osteoblasts and Inhibit Late Stage Differentiation. Journal of Bone and Mineral Research 23:6, pages 928-938.
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Roberto Civitelli. (2008) Cell–cell communication in the osteoblast/osteocyte lineage. Archives of Biochemistry and Biophysics 473:2, pages 188-192.
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Roberto Civitelli, Joseph P. Stains, Chan Soo Shin & Niklas R. Jørgensen. 2008. Principles of Bone Biology. Principles of Bone Biology 425 445 .
Santhi Sridharan, Liz Simon, Daryl D. Meling, Daniel G. Cyr, David E. Gutstein, Glenn I. Fishman, Florian Guillou & Paul S. Cooke. (2007) Proliferation of Adult Sertoli Cells Following Conditional Knockout of the Gap Junctional Protein GJA1 (Connexin 43) in Mice1. Biology of Reproduction 76:5, pages 804-812.
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A. Bellahcène, R. Bachelier, C. Detry, R. Lidereau, P. Clézardin & V. Castronovo. (2006) Transcriptome analysis reveals an osteoblast-like phenotype for human osteotropic breast cancer cells. Breast Cancer Research and Treatment 101:2, pages 135-148.
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Dong Jin Chung, Charlles H. M. Castro, Marcus Watkins, Joseph P. Stains, Min Young Chung, Vera Lucia Szejnfeld, Klaus Willecke, Martin Theis & Roberto Civitelli. (2006) Low peak bone mass and attenuated anabolic response to parathyroid hormone in mice with an osteoblast-specific deletion of connexin43. Journal of Cell Science 119:20, pages 4187-4198.
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SUSAN K. GRIMSTON, JOANNE SCREEN, JENNIFER H. HASKELL, DONG JIN CHUNG, MICHAEL D. BRODT, MATTHEW J. SILVA & ROBERTO CIVITELLI. (2006) Role of Connexin43 in Osteoblast Response to Physical Load. Annals of the New York Academy of Sciences 1068:1, pages 214-224.
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Damian C Genetos & Henry J Donahue. (2005) Intercellular communication and mechanotransduction in bone. Current Opinion in Orthopaedics 16:5, pages 311-315.
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Ph. Debeer, H. Van Esch, C. Huysmans, E. Pijkels, L. De Smet, W. Van de Ven, K. Devriendt & J.-P. Fryns. (2005) Novel GJA1 mutations in patients with oculo-dento-digital dysplasia (ODDD). European Journal of Medical Genetics 48:4, pages 377-387.
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Wendi Roscoe, Gregory I.L. Veitch, Xiang-Qun Gong, Emily Pellegrino, Donglin Bai, Elizabeth McLachlan, Qing Shao, Gerald M. Kidder & Dale W. Laird. (2005) Oculodentodigital Dysplasia-causing Connexin43 Mutants Are Non-functional and Exhibit Dominant Effects on Wild-type Connexin43. Journal of Biological Chemistry 280:12, pages 11458-11466.
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Joseph P. Stains & Roberto Civitelli. (2005) Cell-to-cell interactions in bone. Biochemical and Biophysical Research Communications 328:3, pages 721-727.
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Jiangang Gao, Xudong Wu & Jian Zuo. (2004) Targeting hearing genes in mice. Molecular Brain Research 132:2, pages 192-207.
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