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Journal of Toxicology: Clinical Toxicology Volume 37, 1999 - Issue 1
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Research Article

Aspiration of Activated Charcoal Elicits an Increase in Lung Microvascular Permeability

Thomas C. Arnold Louisiana State University Medical Center, Shreveport
,
Dr. Thomas Arnold Department of Emergency Medicine, Louisiana State University Medical Center, 1501 Kings Highway, Shreveport, LA, 71130, U.S.A.
,
Bradley H. Willis Louisiana State University Medical Center, Shreveport
,
Feng Xiao Louisiana State University Medical Center, Shreveport
,
Steven A. Conrad Louisiana State University Medical Center, Shreveport
&
Donna L. Carden Louisiana State University Medical Center, Shreveport
Pages 9-16 | Published online: 22 Feb 1999

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Lotte C. G. Hoegberg, Greene Shepherd, David M. Wood, Jami Johnson, Robert S. Hoffman, E. Martin Caravati, Wui Ling Chan, Silas W. Smith, Kent R. Olson & Sophie Gosselin. (2021) Systematic review on the use of activated charcoal for gastrointestinal decontamination following acute oral overdose. Clinical Toxicology 59:12, pages 1196-1227.
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American Academy of Clinical Toxicology & European Association of Poisons Centres and Clinical Toxicologists. (2005) Position Paper: Single-Dose Activated Charcoal. Clinical Toxicology 43:2, pages 61-87.
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Donna Seger. (2004) Single‐Dose Activated Charcoal‐Backup and Reassess. Journal of Toxicology: Clinical Toxicology 42:1, pages 101-110.
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Thomas C. Arnold, Shu Zhang, Feng Xiao, Steven A. Conrad & Donna L. Carden. (2003) Pressure-Controlled Ventilation Attenuates Lung Microvascular Injury in a Rat Model of Activated Charcoal Aspiration. Journal of Toxicology: Clinical Toxicology 41:2, pages 119-124.
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Christian Tomaszewski. (1999) Activated Charcoal—Treatment or Toxin?. Journal of Toxicology: Clinical Toxicology 37:1, pages 17-18.
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A. Sloan Witherow, Mandy L. Wallace & Scott A. Secrest. (2019) What Is Your Diagnosis?. Journal of the American Veterinary Medical Association 254:6, pages 673-674.
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Megan N. Caudill, Justin M. Stilwell, Elizabeth W. Howerth & Bridget Garner. (2019) Chronic granulomatous pneumonia and lung rupture secondary to aspiration of activated charcoal in a French Bulldog. Veterinary Clinical Pathology 48:1, pages 67-70.
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Ahmet Mahli, Gozde Inan & Demet Coskun. (2015) Acute respiratory failure and tracheal stenosis following aspiration of activated charcoal. Anaesthesia Cases 3:1, pages 23-25.
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James Tibballs. 2014. Oh's Intensive Care Manual. Oh's Intensive Care Manual 1148 1157.e3 .
Helen E. Wilson & Karen R. Humm. (2013) In vitro study of the effect of dog food on the adsorptive capacity of activated charcoal. Journal of Veterinary Emergency and Critical Care 23:3, pages 263-267.
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Bruna Quaranta Lob?o Bairral, Makoto Saito & Nelson Morrone. (2012) Broncoaspira??o de carv?o ativado. Jornal Brasileiro de Pneumologia 38:4, pages 533-534.
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Ahmet Güzel, Aygül Güzel, Mithat Günaydin, Hasan Alaçam, Osman Şaliş, M. Şükrü Paksu, Naci Murat, Ayhan Gacar & Tolga Güvenç. (2012) The role of iNOS inhibitors on lung injury induced by gastrointestinal decontamination agents aspiration. Journal of Molecular Histology 43:3, pages 351-360.
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Young Il KimJae-Seok ParkJae Sung ChoiSung-Shik JouHyo-Wook GilSae-Yong Hong. (2012) Five Successful Experiences in the Treatment of Charcoal Aspiration with Bronchoscopic Toilet - A Case Report -. Korean Journal of Critical Care Medicine 27:3, pages 202.
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Michael Levine, Daniel E. Brooks, Carrie A. Truitt, Brian J. Wolk, Edward W. Boyer & Anne-Michelle Ruha. (2011) Toxicology in the ICU. Chest 140:3, pages 795-806.
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Geoffrey K. Isbister & Venkata V. Pavan Kumar. (2011) Indications for single-dose activated charcoal administration in acute overdose. Current Opinion in Critical Care 17:4, pages 351-357.
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Donna Seger. 2011. Textbook of Critical Care. Textbook of Critical Care 1265 1269 .
Kent R. Olson. (2010) Activated Charcoal for Acute Poisoning: One Toxicologist’s Journey. Journal of Medical Toxicology 6:2, pages 190-198.
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Suhyun KimNa Ree KangIn SohnHeon LeeYoon Kyung LeeSook Hee Song. (2010) Acute Respiratory Distress Syndrome with Chemical Pneumonitis after Aspiration of Activated Charcoal - A Case Report -. The Korean Journal of Critical Care Medicine 25:2, pages 112.
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Christopher P. Holstege & Pauline E. Meekins. 2010. Clinical Procedures in Emergency Medicine. Clinical Procedures in Emergency Medicine 760 772 .
Sung-Im Do, Sohyung Park, Hongil Ha & Hyoung-Joong Kim. (2009) Fatal pulmonary complications associated with activated charcoal: An autopsy case. Basic and Applied Pathology 2:3, pages 106-108.
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Roland C. E. Francis, Joerg C. Schefold, Sven Bercker, Bettina Temmesfeld-Wollbrück, Wilko Weichert, Claudia D. Spies & Steffen Weber-Carstens. (2008) Acute respiratory failure after aspiration of activated charcoal with recurrent deposition and release from an intrapulmonary cavern. Intensive Care Medicine 35:2, pages 360-363.
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James Tibballs. 2009. Oh's Intensive Care Manual. Oh's Intensive Care Manual 1179 1188 .
Spencer Greene, Cindy Harris & Jonathan Singer. (2008) Gastrointestinal Decontamination of the Poisoned Patient. Pediatric Emergency Care 24:3, pages 176-186.
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Robert Michael Lapus. (2007) Activated charcoal for pediatric poisonings: the universal antidote?. Current Opinion in Pediatrics 19:2, pages 216-222.
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M. Huber, W. Pohl, G. Reinisch, J. Attems, S. Pescosta & F. Lintner. (2006) Lung disease 35 years after aspiration of activated charcoal in combination with pulmonary lymphangioleiomyomatosis. Virchows Archiv 449:2, pages 225-229.
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Isabel Gutiérrez-Cía, Blanca Obón-Azuara, Beatriz Villanueva-Anadón & Raquel Montoiro-Allué. (2006) Insuficiencia respiratoria secundaria a broncoaspiración accidental de carbono activado. Medicina Clínica 126:15, pages 598.
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Kennon Heard. (2006) The Changing Indications of Gastrointestinal Decontamination in Poisonings. Clinics in Laboratory Medicine 26:1, pages 1-12.
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S.V. Mikhalovsky & V.G. Nikolaev. 2006. Activated Carbon Surfaces in Environmental Remediation. Activated Carbon Surfaces in Environmental Remediation 529 561 .
Kennon Heard. (2005) Gastrointestinal Decontamination. Medical Clinics of North America 89:6, pages 1067-1078.
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LeRoy W. Essig & James N. Allen. (2005) RESPIRATORY FAILURE AND REFRACTORY HYPOXEMIA DUE TO ACTIVATED CHARCOAL ASPIRATION: TREATMENT WITH BRONCHOSCOPIC SURFACTANT ADMINISTRATION. Chest 128:4, pages 479S.
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Kevin C. Osterhoudt, Elizabeth R. Alpern, Dennis Durbin, Frances Nadel & Fred M. Henretig. (2004) Activated Charcoal Administration in a Pediatric Emergency Department. Pediatric Emergency Care 20:8, pages 493-498.
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Alejandro Donoso, Marcela Linares, Jos? Le?n, Gloria Rojas, Cristi?n Valverde, Milena Ram?rez & Bernd Oberpaur. (2003) Activated Charcoal Laryngitis in an Intubated Patient. Pediatric Emergency Care 19:6, pages 420-421.
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Gavin R. Graff, James Stark, John W. Berkenbosch, George W. HolcombIIIIII & Robert E. Garola. (2002) Chronic Lung Disease After Activated Charcoal Aspiration. Pediatrics 109:5, pages 959-961.
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G.Randall Bond. (2002) The role of activated charcoal and gastric emptying in gastrointestinal decontamination: A state-of-the-art review. Annals of Emergency Medicine 39:3, pages 273-286.
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Johann Golej, Harald Boigner, Gudrun Burda, Michael Hermon & Gerhard Trittenwein. (2001) Severe respiratory failure following charcoal application in a toddler. Resuscitation 49:3, pages 315-318.
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E.Martin Caravati, Heather H Knight, M.Scott LinscottJrJr & James C Stringham. (2001) Esophageal laceration and charcoal mediastinum complicating gastric lavage. The Journal of Emergency Medicine 20:3, pages 273-276.
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Guy C. Petroz & Jerrold Lerman. (2000) Pulmonary aspiration and lung injury. Current Opinion in Anaesthesiology 13:3, pages 291-297.
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Michele M. Burns. (2000) Activated charcoal as the sole intervention for treatment after childhood poisoning. Current Opinion in Pediatrics 12:2, pages 166-171.
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Michael Shannon. (2000) Ingestion of Toxic Substances by Children. New England Journal of Medicine 342:3, pages 186-191.
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