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Research Article

Toxic Effects of Arsenic (III) on Some Hematopoietic and Central Nervous System Variables in Rats and Guinea Pigs

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Pages 675-682 | Published online: 31 Dec 2001

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Mohsen Vigeh, Kazuhito Yokoyama, Takehisa Matsukawa, Atsuko Shinohara & Katsumi Ohtani. (2015) The Relation of Maternal Blood Arsenic to Anemia During Pregnancy. Women & Health 55:1, pages 42-57.
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Avani G.M.V. Rao. (2009) Toxicological effects of arsenic and its modulation by vitamin A in the brain and blood of Swiss albino mice. Toxicological & Environmental Chemistry 91:1, pages 65-74.
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S. J. S. Flora, G. M. Kannan, B. P. Pant & D. K. Jaiswal. (2003) The Efficacy of Monoisoamyl Ester of Dimercaptosuccinic Acid in Chronic Experimental Arsenic Poisoning in Mice. Journal of Environmental Science and Health, Part A 38:1, pages 241-254.
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Subhash Chandra Mukherjee, Mohammad Mahmudur Rahman, Uttam Kumar Chowdhury, Mrinal Kumar Sengupta, Dilip Lodh, Chitta Ranjan Chanda, Kshitish Chandra Saha & Dipankar Chakraborti. (2003) Neuropathy in Arsenic Toxicity from Groundwater Arsenic Contamination in West Bengal, India. Journal of Environmental Science and Health, Part A 38:1, pages 165-183.
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Mohammad Mahmudur Rahman, Uttam Kumar Chowdhury, Subhash Chandra Mukherjee, Badal Kumar Mondal, Kunal Paul, Dilip Lodh, Bhajan Kumar Biswas, Chitta Ranjan Chanda, Gautam Kumar Basu, Kshitish Chandra Saha, Shibtosh Roy, Ranajit Das, Shyamal Kanti Palit, Quazi Quamruzzaman & Dipankar Chakraborti. (2001) Chronic Arsenic Toxicity in Bangladesh and West Bengal, India—A Review and Commentary. Journal of Toxicology: Clinical Toxicology 39:7, pages 683-700.
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Feng Qiu, Hongling Zhang, Hongxiu Liu, Tongzhang Zheng, Wei Xia, Shunqing Xu, Han Xiao & Yuanyuan Li. (2023) Association of arsenic exposure and clinical hematological changes during pregnancy: Findings from a prospective Wuhan birth cohort study. Environmental Research 224, pages 115559.
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Cheng Zhang, Yanyao Li, Haibo Yu, Limin Ye, Tian Li, Xiaotian Zhang, Chi Wang, Pengju Li, Hong Ji, Qinfeng Gao & Shuanglin Dong. (2023) Nanoplastics promote arsenic-induced ROS accumulation, mitochondrial damage and disturbances in neurotransmitter metabolism of zebrafish (Danio rerio). Science of The Total Environment 863, pages 161005.
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Riyaz Basha, Ashni Dudhia & G. Rajarami Reddy. 2023. Handbook of Arsenic Toxicology. Handbook of Arsenic Toxicology 501 516 .
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Humairat H Rahman, Danielle Niemann & Korede K Yusuf. (2021) Association of urinary arsenic and sleep disorder in the US population: NHANES 2015–2016. Environmental Science and Pollution Research 29:4, pages 5496-5504.
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Manisha Thakur, Mahesh Rachamalla, Som Niyogi, Ashok Kumar Datusalia & Swaran Jeet Singh Flora. (2021) Molecular Mechanism of Arsenic-Induced Neurotoxicity including Neuronal Dysfunctions. International Journal of Molecular Sciences 22:18, pages 10077.
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Kamakshi Mehta, Kamlesh Kumar Pandey, Balpreet Kaur, Pushpa Dhar & Saroj Kaler. (2021) Resveratrol attenuates arsenic-induced cognitive deficits via modulation of Estrogen-NMDAR-BDNF signalling pathway in female mouse hippocampus. Psychopharmacology 238:9, pages 2485-2502.
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Shilpi Dixit, Raj D. Mehra & Pushpa Dhar. (2020) Effect of α-lipoic acid on spatial memory and structural integrity of developing hippocampal neurons in rats subjected to sodium arsenite exposure. Environmental Toxicology and Pharmacology 75, pages 103323.
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Qing-Xin Ren, Meng-Chuan Xu, Qiang Niu, Yun-Hua Hu, Hai-Xia Wang & Shu-Gang Li. (2019) Effects of Proanthocyanidins on Arsenic Methylation Metabolism and Efflux in Human Hepatocytes L-02. BioMed Research International 2019, pages 1-11.
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F. Arcega-Cabrera, L. Fargher, M. Quesadas-Rojas, R. Moo-Puc, I. Oceguera-Vargas, E. Noreña-Barroso, L. Yáñez-Estrada, J. Alvarado, L. González, N. Pérez-Herrera & S. Pérez-Medina. (2018) Environmental Exposure of Children to Toxic Trace Elements (Hg, Cr, As) in an Urban Area of Yucatan, Mexico: Water, Blood, and Urine Levels. Bulletin of Environmental Contamination and Toxicology 100:5, pages 620-626.
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MR Kumar & GR Reddy. (2017) Influence of age on arsenic-induced behavioral and cholinergic perturbations: Amelioration with zinc and α-tocopherol. Human & Experimental Toxicology 37:3, pages 295-308.
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Fakiha Firdaus, Mohd Faraz Zafeer, Ehraz Anis, Masood Ahmad & Mohammad Afzal. (2018) Ellagic acid attenuates arsenic induced neuro-inflammation and mitochondrial dysfunction associated apoptosis. Toxicology Reports 5, pages 411-417.
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F. Arcega-Cabrera, L. F. Fargher, I. Oceguera-Vargas, E. Noreña-Barroso, L. Yánez-Estrada, J. Alvarado, L. González, R. Moo-Puc, N. Pérez-Herrera, M. Quesadas-Rojas & S. Pérez-Medina. (2017) Water Consumption as Source of Arsenic, Chromium, and Mercury in Children Living in Rural Yucatan, Mexico: Blood and Urine Levels. Bulletin of Environmental Contamination and Toxicology 99:4, pages 452-459.
Crossref
A. Hartwig. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1558 1641 .
Guanghua Mao, Zhaoxiang Zhou, Yao Chen, Wei Wang, Xueshan Wu, Weiwei Feng, Samuel Jerry Cobbina, Jing Huang, Zhen Zhang, Hai Xu, Liuqing Yang & Xiangyang Wu. (2015) Neurological Toxicity of Individual and Mixtures of Low Dose Arsenic, Mono and Di (n-butyl) Phthalates on Sub-Chronic Exposure to Mice. Biological Trace Element Research 170:1, pages 183-193.
Crossref
Chandra Prakash, Manisha Soni & Vijay Kumar. (2016) Mitochondrial oxidative stress and dysfunction in arsenic neurotoxicity: A review. Journal of Applied Toxicology 36:2, pages 179-188.
Crossref
Shruti Agrawal, Pradeep Bhatnagar & S.J.S. Flora. (2015) Changes in tissue oxidative stress, brain biogenic amines and acetylcholinesterase following co-exposure to lead, arsenic and mercury in rats. Food and Chemical Toxicology 86, pages 208-216.
Crossref
Dominic B. Fee. 2015. Arsenic. Arsenic 193 219 .
P. Sánchez-Virosta, S. Espín, A.J. García-Fernández & T. Eeva. (2015) A review on exposure and effects of arsenic in passerine birds. Science of The Total Environment 512-513, pages 506-525.
Crossref
Oliver A. H. Jones, Daniel A. Dias, Damien L. Callahan, Konstantinos A. Kouremenos, David J. Beale & Ute Roessner. (2015) The use of metabolomics in the study of metals in biological systems. Metallomics 7:1, pages 29-38.
Crossref
Swaran J.S. Flora. 2015. Handbook of Toxicology of Chemical Warfare Agents. Handbook of Toxicology of Chemical Warfare Agents 171 191 .
Ashish Mehta, Chrishan J.A. Ramachandra & Winston Shim. 2015. Handbook of Arsenic Toxicology. Handbook of Arsenic Toxicology 459 491 .
Riyaz Basha & G. Rajarami Reddy. 2015. Handbook of Arsenic Toxicology. Handbook of Arsenic Toxicology 443 457 .
Vanda Andrade, M. Luísa Mateus, M. Camila Batoréu, Michael Aschner & A.P. Marreilha dos Santos. (2014) Changes in rat urinary porphyrin profiles predict the magnitude of the neurotoxic effects induced by a mixture of lead, arsenic and manganese. NeuroToxicology 45, pages 168-177.
Crossref
Haiyan Zhu, Yijing Jia, Hongbin Cao, Fanyun Meng & Xinxin Liu. (2014) Biochemical and histopathological effects of subchronic oral exposure of rats to a mixture of five toxic elements. Food and Chemical Toxicology 71, pages 166-175.
Crossref
Karunakaran Vijayakaran, Manickam Kesavan, Kandasamy Kannan, Palanisamy Sankar, Surendra Kumar Tandan & Souvendra Nath Sarkar. (2014) Arsenic decreases antinociceptive activity of paracetamol: Possible involvement of serotonergic and endocannabinoid receptors. Environmental Toxicology and Pharmacology 38:2, pages 397-405.
Crossref
. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 77 .
Christine Neslund-Dudas, Albert M. Levin, Andrew Rundle, Jennifer Beebe-Dimmer, Cathryn H. Bock, Nora L. Nock, Michelle Jankowski, Indrani Datta, Richard Krajenta, Q. Ping Dou, Bharati Mitra, Deliang Tang & Benjamin A. Rybicki. (2014) Case-only gene-environment interaction between ALAD tagSNPs and occupational lead exposure in prostate cancer . The Prostate 74:6, pages 637-646.
Crossref
Chan-Wei Yu & Vivian Hsiu-Chuan Liao. (2014) Arsenite induces neurotoxic effects on AFD neurons via oxidative stress in Caenorhabditis elegans. Metallomics 6:10, pages 1824-1831.
Crossref
M. Ram Kumar, S.J.S. Flora & G.R. Reddy. (2013) Monoisoamyl 2,3-dimercaptosuccinic acid attenuates arsenic induced toxicity: Behavioral and neurochemical approach. Environmental Toxicology and Pharmacology 36:1, pages 231-242.
Crossref
Mahfoud Messarah, Mongi Saoudi, Amel Boumendjel, Lilia Kadeche, Mohamed Salah Boulakoud & Abdelfattah El Feki. (2012) Green tea extract alleviates arsenic-induced biochemical toxicity and lipid peroxidation in rats. Toxicology and Industrial Health 29:4, pages 349-359.
Crossref
Vidhu Pachauri, Ashish Mehta, Deepshikha Mishra & Swaran J.S. Flora. (2013) Arsenic induced neuronal apoptosis in guinea pigs is Ca2+ dependent and abrogated by chelation therapy: Role of voltage gated calcium channels. NeuroToxicology 35, pages 137-145.
Crossref
Muhammad Shahdaat Bin Sayeed, Md. Ratan, Farhad Hossen, Faizule Hassan, Mohammad Faisal & Mohammad Fahim Kadir. (2012) Arsenosugar Induced Blood and Brain Oxidative Stress, DNA Damage and Neurobehavioral Impairments. Neurochemical Research 38:2, pages 405-412.
Crossref
Sunny O. Abarikwu. 2013. Pollutant Diseases, Remediation and Recycling. Pollutant Diseases, Remediation and Recycling 351 386 .
Yachen Wang, Fengyuan Piao, Yachen Li, Xianghu Wang & Huai Guang. 2013. Taurine 8. Taurine 8 155 166 .
Vidhu Pachauri, Mohit Dubey, Abhishek Yadav, Pramod Kushwaha & S.J.S. Flora. (2012) Monensin potentiates lead chelation efficacy of MiADMSA in rat brain post chronic lead exposure. Food and Chemical Toxicology 50:12, pages 4449-4460.
Crossref
Sally Ahmad Selim, Assmaa O. Selim & Eman M. Askar. (2012) Harmful effects of arsenic on the cerebral cortex of adult male albino rats. The Egyptian Journal of Histology 35:2, pages 249-258.
Crossref
Luis Antonio Baldissarelli, Katiucia Marques Capiotti, Mauricio Reis Bogo, Gabriele Ghisleni & Carla Denise Bonan. (2012) Arsenic alters behavioral parameters and brain ectonucleotidases activities in zebrafish (Danio rerio). Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 155:4, pages 566-572.
Crossref
Mahfoud Messarah, Fahima Klibet, Amel Boumendjel, Cherif Abdennour, Noureddine Bouzerna, Mohamed Salah Boulakoud & Abdelfattah El Feki. (2012) Hepatoprotective role and antioxidant capacity of selenium on arsenic-induced liver injury in rats. Experimental and Toxicologic Pathology 64:3, pages 167-174.
Crossref
Rajesh S. Yadav, Lalit P. Chandravanshi, Rajendra K. Shukla, Madhu L. Sankhwar, Reyaz W. Ansari, Pradeep K. Shukla, Aditya B. Pant & Vinay K. Khanna. (2011) Neuroprotective efficacy of curcumin in arsenic induced cholinergic dysfunctions in rats. NeuroToxicology 32:6, pages 760-768.
Crossref
Nidhi Dwivedi, Ashish Mehta, Abhishek Yadav, B.K. Binukumar, Kiran Dip Gill & Swaran J.S. Flora. (2011) MiADMSA reverses impaired mitochondrial energy metabolism and neuronal apoptotic cell death after arsenic exposure in rats. Toxicology and Applied Pharmacology 256:3, pages 241-248.
Crossref
L. Pari & A. Mohamed Jalaludeen. (2011) Protective role of sinapic acid against arsenic – Induced toxicity in rats. Chemico-Biological Interactions 194:1, pages 40-47.
Crossref
Margaret H. Whittaker, Gensheng Wang, Xue-Qing Chen, Michael Lipsky, Donald Smith, Roberto Gwiazda & Bruce A. Fowler. (2011) Exposure to Pb, Cd, and As mixtures potentiates the production of oxidative stress precursors: 30-day, 90-day, and 180-day drinking water studies in rats. Toxicology and Applied Pharmacology 254:2, pages 154-166.
Crossref
Klaudia Jomova & Marian Valko. (2011) Advances in metal-induced oxidative stress and human disease. Toxicology 283:2-3, pages 65-87.
Crossref
Anshu Jain, Abhishek Yadav, A.I. Bozhkov, V.I. Padalko & S.J.S. Flora. (2011) Therapeutic efficacy of silymarin and naringenin in reducing arsenic-induced hepatic damage in young rats. Ecotoxicology and Environmental Safety 74:4, pages 607-614.
Crossref
K. Jomova, Z. Jenisova, M. Feszterova, S. Baros, J. Liska, D. Hudecova, C. J. Rhodes & M. Valko. (2011) Arsenic: toxicity, oxidative stress and human disease. Journal of Applied Toxicology 31:2, pages 95-107.
Crossref
Fengyuan PIAO, Sheng LI, Qiujuan LI, Jianxin YE & Shuang LIU. (2011) Abnormal Expression of 8-Nitroguanine in the Brain of Mice Exposed to Arsenic Subchronically. INDUSTRIAL HEALTH Industrial Health 49:2, pages 151-157.
Crossref
Vivian Hsiu-Chuan Liao, Jui-Tung Liu, Wen-Hsuan Li, Chan-Wei Yu & Yi-Chen Hsieh. (2010) Caenorhabditis elegans Bicarbonate Transporter ABTS-1 Is Involved in Arsenite Toxicity and Cholinergic Signaling . Chemical Research in Toxicology 23:5, pages 926-932.
Crossref
Keiko Ozone, Seiichi Ueno, Mutsuo Ishizaki & Osamu Hayashi. (2010) Toxicity and Oxidative Stress Induced by Organic Arsenical Diphenylarsinic Acid and Inorganic Arsenicals and Their Effects on Spatial Learning Ability in Mice. JOURNAL OF HEALTH SCIENCE Journal of Health Science 56:5, pages 517-526.
Crossref
Rajesh S. Yadav, Madhu Lata Sankhwar, Rajendra K. Shukla, Ramesh Chandra, Aditya B. Pant, Fakhrul Islam & Vinay K. Khanna. (2009) Attenuation of arsenic neurotoxicity by curcumin in rats. Toxicology and Applied Pharmacology 240:3, pages 367-376.
Crossref
Vidhu Pachauri, Geetu Saxena, Ashish Mehta, Deepshikha Mishra & Swaran J.S. Flora. (2009) Combinational chelation therapy abrogates lead-induced neurodegeneration in rats. Toxicology and Applied Pharmacology 240:2, pages 255-264.
Crossref
Marie Vahter. (2009) Effects of Arsenic on Maternal and Fetal Health. Annual Review of Nutrition 29:1, pages 381-399.
Crossref
Shuhua Xi, Wenjuan Sun, Fengzhi Wang, Yaping Jin & Guifan Sun. (2009) Transplacental and early life exposure to inorganic arsenic affected development and behavior in offspring rats. Archives of Toxicology 83:6, pages 549-556.
Crossref
Swaran J.S. Flora, Govinder Flora & Geetu Saxena. 2009. Handbook of Toxicology of Chemical Warfare Agents. Handbook of Toxicology of Chemical Warfare Agents 109 133 .
M Gonsebatt, J Limón-Pacheco, E Uribe-Querol, G Gutiérrez-Ospina, V Rodríguez, M M. Giordano, L Del Razo & L Sánchez-Peña. 2008. Natural Arsenic in Groundwaters of Latin America. Natural Arsenic in Groundwaters of Latin America 459 466 .
Julia E. Heck, Yu Chen, Victor R. Grann, Vesna Slavkovich, Faruque Parvez & Habibul Ahsan. (2008) Arsenic Exposure and Anemia in Bangladesh: A Population-Based Study. Journal of Occupational & Environmental Medicine 50:1, pages 80-87.
Crossref
Manoj Modi, Ramesh K. Kaul, Gurusamy M. Kannan & Swaran J.S. Flora. (2006) Co-administration of zinc and n-acetylcysteine prevents arsenic-induced tissue oxidative stress in male rats. Journal of Trace Elements in Medicine and Biology 20:3, pages 197-204.
Crossref
D. Nandi, R.C. Patra & D. Swarup. (2006) Oxidative stress indices and plasma biochemical parameters during oral exposure to arsenic in rats. Food and Chemical Toxicology 44:9, pages 1579-1584.
Crossref
Katharina Krüger, Norbert Binding, Heidrun Straub & Ulrich Mußhoff. (2006) Effects of arsenite on long-term potentiation in hippocampal slices from young and adult rats. Toxicology Letters 165:2, pages 167-173.
Crossref
Claudia Hopenhayn, Heather M. Bush, Alexander Bingcang & Irva Hertz-Picciotto. (2006) Association Between Arsenic Exposure From Drinking Water and Anemia During Pregnancy. Journal of Occupational and Environmental Medicine 48:6, pages 635-643.
Crossref
Carrie V. Breton, E. Andres Houseman, Molly L. Kile, Quazi Quamruzzaman, Mahmuder Rahman, Golam Mahiuddin & David C. Christiani. (2006) Gender-Specific Protective Effect of Hemoglobin on Arsenic-Induced Skin Lesions. Cancer Epidemiology, Biomarkers & Prevention 15:5, pages 902-907.
Crossref
D. Nandi, R.C. Patra & D. Swarup. (2005) Effect of cysteine, methionine, ascorbic acid and thiamine on arsenic-induced oxidative stress and biochemical alterations in rats. Toxicology 211:1-2, pages 26-35.
Crossref
Dante D. Caceres, Paulina Pino, Nestor Montesinos, Eduardo Atalah, Hugo Amigo & Dana Loomis. (2005) Exposure to inorganic arsenic in drinking water and total urinary arsenic concentration in a Chilean population. Environmental Research 98:2, pages 151-159.
Crossref
Félix Antunes Soares, Marcelo Farina, Alfério C. Böettcher, Antônio L. Braga & João Batista T. Rocha. (2005) Organic and inorganic forms of selenium inhibited differently fish (Rhamdia quelen) and rat (Rattus norvergicus albinus) δ-aminolevulinate dehydratase. Environmental Research 98:1, pages 46-54.
Crossref
Richa Gupta & Swaran J. S. Flora. (2005) Protective value of Aloe vera against some toxic effects of arsenic in rats . Phytotherapy Research 19:1, pages 23-28.
Crossref

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