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Journal of Toxicology: Clinical Toxicology Volume 41, 2003 - Issue 2
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Research Article

Cardiotoxicity Associated with Intentional Ziprasidone and Bupropion Overdose#

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Abhik K. Biswas M.D., F.A.A.P., Pediatric Critical Care Medicine, Naval Medical Center Portsmouth, Portsmouth, VirginiaUSA
,
Luke A. Zabrocki M.D., Pediatric Critical Care Medicine, Naval Medical Center Portsmouth, Portsmouth, VirginiaUSA
,
Kendra L. Mayes Pharm.D., Pediatric Critical Care Medicine, Naval Medical Center Portsmouth, Portsmouth, VirginiaUSA
&
Cynthia L. Morris-Kukoski, Pharm.D., D.A.B.A.T. Navy Drug Screening Laboratory Great Lakes, Great Lakes, IllinoisUSA
Pages 101-104 | Published online: 04 Sep 2003

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Michael Simpson, Linda Johnson & Charlotte Goldfine. (2023) Sodium bicarbonate treatment for QRS widening in bupropion overdoses. Clinical Toxicology 61:6, pages 436-444.
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S. A. Al-Abri, J. P. Orengo, S. Hayashi, K. L. Thoren, N. L. Benowitz & K. R. Olson. (2013) Delayed bupropion cardiotoxicity associated with elevated serum concentrations of bupropion but not hydroxybupropion. Clinical Toxicology 51:10, pages 1230-1234.
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Florian Morazin, Agnès Lumbroso, Patrick Harry, Marcel Blaise, Alain Turcant, Philippe Montravers & Rémy Gauzit. (2007) Cardiogenic shock and status epilepticus after massive bupropion overdose. Clinical Toxicology 45:7, pages 794-797.
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Wendy Klein-Schwartz, Amanda L. Lofton, Blaine E. Benson, Henry A. Spiller & Barbara I. Crouch. (2007) Prospective observational multi-poison center study of ziprasidone exposures. Clinical Toxicology 45:7, pages 782-786.
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Articles from other publishers (16)

Biswadeep Das, Vikram Singh Rawat, Saravana Kumar Ramasubbu, Akash Agnihotri & Barun Kumar. (2022) Potential drug-drug interaction prevalence and risk factors associated with QT interval prolonging psychotropic use in children and adolescents. Progress in Pediatric Cardiology 64, pages 101456.
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Marianna S. Rivas-Coppola, Amy L. Patterson, Robin Morgan & James W. Wheless. (2015) Bupropion Overdose Presenting as Status Epilepticus in an Infant. Pediatric Neurology 53:3, pages 257-261.
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Mehrul Hasnain & W. Victor R. Vieweg. (2014) QTc Interval Prolongation and Torsade de Pointes Associated with Second-Generation Antipsychotics and Antidepressants: A Comprehensive Review. CNS Drugs 28:10, pages 887-920.
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Bertrand Caillier, Sylvie Pilote, Annie Castonguay, Dany Patoine, Verlaine Ménard-Desrosiers, Patrick Vigneault, Raymond Hreiche, Jacques Turgeon, Pascal Daleau, Yves De Koninck, Chantale Simard & Benoit Drolet. (2012) QRS widening and QT prolongation under bupropion: a unique cardiac electrophysiological profile. Fundamental & Clinical Pharmacology 26:5, pages 599-608.
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Chia-Ter Chao, Vin-Cent Wu & Wei-Jie Wang. (2012) Charcoal hemoperfusion for bupropion overdose with ventricular tachycardia and status epilepticus. Journal of the Formosan Medical Association 111:1, pages 51-52.
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Chip Gresham & Anne M. Ruha. (2010) Respiratory Failure Following Isolated Ziprasidone Ingestion in a Toddler. Journal of Medical Toxicology 6:1, pages 41-43.
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Hock Heng Tan, Jason Hoppe & Kennon Heard. (2009) A systematic review of cardiovascular effects after atypical antipsychotic medication overdose. The American Journal of Emergency Medicine 27:5, pages 607-616.
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Brandon K Wills, Michele Zell-Kanter & Steven E Aks. (2009) Bupropion-Associated QRS Prolongation Unresponsive to Sodium Bicarbonate Therapy. American Journal of Therapeutics 16:2, pages 193-196.
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Melissa L. Givens & Jeremy Gabrysch. (2007) Cardiotoxicity Associated With Accidental Bupropion Ingestion in a Child. Pediatric Emergency Care 23:4, pages 234-237.
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Paul McNally, Fiona McNicholas & Paul Oslizlok. (2006) The QT interval and psychotropic medications in children. European Child & Adolescent Psychiatry 16:1, pages 33-47.
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WESLEY PALATNICK. 2007. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose 549 559 .
Douglas A. Rund, John D. Ewing, Katherine Mitzel & Nicholas Votolato. (2006) The use of intramuscular benzodiazepines and antipsychotic agents in the treatment of acute agitation or violence in the emergency department. The Journal of Emergency Medicine 31:3, pages 317-324.
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W. Haverkamp & M. Deuschle. (2006) Antipsychotikainduzierte QT-VerlängerungLengthening of QT interval by antipsychotic drugs. Der Nervenarzt 77:3, pages 276-288.
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Smita X. AntiaEllen H. SholevarDavid A. Baron. (2005) Overdoses and Ingestions of Second-Generation Antipsychotics in Children and Adolescents. Journal of Child and Adolescent Psychopharmacology 15:6, pages 970-985.
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Steven C. Curry, John S. Kashani, Frank LoVecchio & William Holubek. (2005) Intraventricular conduction delay after bupropion overdose. The Journal of Emergency Medicine 29:3, pages 299-305.
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Dmitry M. Arbuck. (2005) 12,800-mg ziprasidone overdose without significant ECG changes. General Hospital Psychiatry 27:3, pages 222-223.
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