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Research Article

The Abrupt Cessation of Therapeutically Administered Sodium Oxybate (GHB) Does Not Cause Withdrawal Symptoms

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Pages 131-135 | Published online: 04 Sep 2003

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Ashima S Sahni, Melissa Carlucci, Malik Malik & Bharati Prasad. (2019) Management Of Excessive Sleepiness In Patients With Narcolepsy And OSA: Current Challenges And Future Prospects. Nature and Science of Sleep 11, pages 241-252.
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Martin B Scharf. (2006) Sodium oxybate for narcolepsy. Expert Review of Neurotherapeutics 6:8, pages 1139-1146.
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Anna Heidbreder, Christina Dirks & Markus Ramm. (2020) Therapy for Cataplexy. Current Treatment Options in Neurology 22:4.
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Sally Hu, Mandeep Singh, Jean Wong, Dennis Auckley, Shelley Hershner, Rahul Kakkar, Michael J. ThorpyFrances Chung. (2018) Anesthetic Management of Narcolepsy Patients During Surgery: A Systematic Review. Anesthesia & Analgesia 126:1, pages 233-246.
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Sarah Wurts Black, Akihiro Yamanaka & Thomas S. Kilduff. (2017) Challenges in the development of therapeutics for narcolepsy. Progress in Neurobiology 152, pages 89-113.
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Emmanuel J. M. Mignot. (2012) A Practical Guide to the Therapy of Narcolepsy and Hypersomnia Syndromes. Neurotherapeutics 9:4, pages 739-752.
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Sanjeev V. KothareJoseph Kaleyias. (2017) Pharmacotherapy of Narcolepsy: Focus on Sodium Oxybate. Clinical Medicine Insights: Therapeutics 2, pages CMT.S1087.
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Lawrence P. Carter & Roland R. Griffiths. (2009) Principles of laboratory assessment of drug abuse liability and implications for clinical development. Drug and Alcohol Dependence 105, pages S14-S25.
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Lawrence P. Carter, Daniel Pardi, Jane Gorsline & Roland R. Griffiths. (2009) Illicit gamma-hydroxybutyrate (GHB) and pharmaceutical sodium oxybate (Xyrem®): Differences in characteristics and misuse. Drug and Alcohol Dependence 104:1-2, pages 1-10.
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A. K. Goodwin, P. R. Brown, E. E. W. Jansen, C. Jakobs, K. M. Gibson & E. M. Weerts. (2009) Behavioral effects and pharmacokinetics of gamma-hydroxybutyrate (GHB) precursors gamma-butyrolactone (GBL) and 1,4-butanediol (1,4-BD) in baboons. Psychopharmacology 204:3, pages 465-476.
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Ruzica K. Ristanovic, Howard Liang, Carl S. Hornfeldt & Chinglin Lai. (2009) Exacerbation of cataplexy following gradual withdrawal of antidepressants: Manifestation of probable protracted rebound cataplexy. Sleep Medicine 10:4, pages 416-421.
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Joshua T. Kantrowitz, Leslie Citrome & Daniel C. Javitt. (2009) A review of tolerability and abuse liability of γ-hydroxybutyric acid for insomnia in patients with schizophrenia. Clinical Therapeutics 31, pages 1360-1373.
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Qanta A. Ahmed. (2008) Effects of Common Medications Used for Sleep Disorders. Critical Care Clinics 24:3, pages 493-515.
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LAWRENCE S. QUANG. 2007. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose 803 823 .
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Jonathan RL Schwartz. (2006) Emerging treatment options for excessive sleepiness associated with narcolepsy. Therapy 3:3, pages 375-382.
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Michael D Lemon, Joe D Strain & Debra K Farver. (2016) Formulary Forum: Sodium Oxybate for Cataplexy. Annals of Pharmacotherapy 40:3, pages 433-440.
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Michael J Thorpy. (2006) Cataplexy Associated with Narcolepsy. CNS Drugs 20:1, pages 43-50.
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Elise M. Weerts, Amy K. Goodwin, Roland R. Griffiths, P. Rand Brown, Wolfgang Froestl, Cornelis Jakobs & K. Michael Gibson. (2005) Spontaneous and precipitated withdrawal after chronic intragastric administration of gamma-hydroxybutyrate (GHB) in baboons. Psychopharmacology 179:3, pages 678-687.
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