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Case Report

Massive Caffeine Overdose Requiring Vasopressin Infusion and Hemodialysis

, M.D., , , , &
Pages 1003-1007 | Published online: 12 Mar 2003

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Kaliana Larissa Machado, Poliana Camila Marinello, Thamara Nishida Xavier Silva, Cássio Fernando Nunes Silva, Rodrigo Cabral Luiz, Rubens Cecchini & Alessandra Lourenço Cecchini. (2021) Oxidative Stress in Caffeine Action on the Proliferation and Death of Human Breast Cancer Cells MCF-7 and MDA-MB-231. Nutrition and Cancer 73:8, pages 1378-1388.
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Marc Ghannoum, Timothy J. Wiegand, Kathleen D. Liu, Diane P. Calello, Melanie Godin, Valery Lavergne, Sophie Gosselin, Thomas D. Nolin & Robert S. Hoffman. (2015) Extracorporeal treatment for theophylline poisoning: Systematic review and recommendations from the EXTRIP workgroup. Clinical Toxicology 53:4, pages 215-229.
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A. Kamour, D. James, R. Spears, G. Cooper, D. J. Lupton, M. Eddleston, J. P. Thompson, A. J. Vale, H. K. R. Thanacoody, S. L. Hill & S. H. L. Thomas. (2014) Patterns of presentation and clinical toxicity after reported use of alpha methyltryptamine in the United Kingdom. A report from the UK National Poisons Information Service. Clinical Toxicology 52:3, pages 192-197.
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Karthikeyan Kanagarajan, Jeanna M. Marraffa, Nicole C. Bouchard, Padmanabhan Krishnan, Robert S. Hoffman & Christine M. Stork. (2007) The use of vasopressin in the setting of recalcitrant hypotension due to calcium channel blocker overdose. Clinical Toxicology 45:1, pages 56-59.
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Joel S. Holger, Kristin M. Engebretsen, Christopher L. Obetz, Tanya L. Kleven & Carson R. Harris. (2006) A Comparison of Vasopressin and Glucagon in Beta-Blocker Induced Toxicity. Clinical Toxicology 44:1, pages 45-51.
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Matthew Lambrych. 2024. Encyclopedia of Toxicology. Encyclopedia of Toxicology 417 425 .
Xinjie Song, Nikhil Kirtipal, Sunjae Lee, Petr Malý & Shiv Bharadwaj. (2023) Current therapeutic targets and multifaceted physiological impacts of caffeine. Phytotherapy Research.
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Christian C Toquica Gahona, Ashwin Kodagnur Bharadwaj, Monarch Shah, Umesh Bhagat, Paul Sterman & William Vasquez. (2022) Treatment of Lethal Caffeine Overdose with Haemodialysis: A Case Report and Review. The Journal of Critical Care Medicine 8:4, pages 279-287.
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Daisuke Kobashi, Yoshito Kamijo, Tomoki Hanazawa, Tomohiro Yoshizawa & Mitsunobu Nakamura. (2022) Severe caffeine poisoning successfully treated with high flow continuous hemodialysis. The American Journal of Emergency Medicine 58, pages 351.e3-351.e5.
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Hao-Cho Ou, Jou-Fang Deng, Chen-Chang Yang, Chin-Sheng Lin, Yan-Chiao Mao, Shih-Hung Tsai & Cheng-Hsuan Ho. (2022) A successful experience using labetalol and hemodialysis to treat near-fatal caffeine poisoning: A case report with toxicodynamics. The American Journal of Emergency Medicine 55, pages 224.e1-224.e4.
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Charles Hensher & John Vogel. (2020) High-Dose Insulin Euglycemic Therapy in the Treatment of a Massive Caffeine Overdose. Chest 157:5, pages e145-e149.
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Benjamin A. Kohl, Kuljit Kaur, Nathan Dincher, Jessica Schumann, Tara Carachilo & Christopher Komurek. (2020) Acute intentional caffeine overdose treated preemptively with hemodialysis. The American Journal of Emergency Medicine 38:3, pages 692.e1-692.e3.
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Yumi Kato, Akira Kuriyama, Reo Hata & Tetsunori Ikegami. (2020) Extracorporeal Membrane Oxygenation for Hypokalemia and Refractory Ventricular Fibrillation Associated with Caffeine Intoxication. The Journal of Emergency Medicine 58:1, pages 59-62.
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Jian-Da Lu & Jun Xue. 2019. Critical Care Nephrology. Critical Care Nephrology 600 629.e7 .
Yoshito Kamijo, Michiko Takai, Yuji Fujita & Kiyotaka Usui. (2018) A Retrospective Study on the Epidemiological and Clinical Features of Emergency Patients with Large or Massive Consumption of Caffeinated Supplements or Energy Drinks in Japan. Internal Medicine 57:15, pages 2141-2146.
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Cyril Willson. (2018) The clinical toxicology of caffeine: A review and case study. Toxicology Reports 5, pages 1140-1152.
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Daniele Wikoff, Brian T. Welsh, Rayetta Henderson, Gregory P. Brorby, Janice Britt, Esther Myers, Jeffrey Goldberger, Harris R. Lieberman, Charles O'Brien, Jennifer Peck, Milton Tenenbein, Connie Weaver, Seneca Harvey, Jonathan Urban & Candace Doepker. (2017) Systematic review of the potential adverse effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children. Food and Chemical Toxicology 109, pages 585-648.
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Jan Magdalan, Marcin Zawadzki, Rafał Skowronek, Magdalena Czuba, Barbara Porębska, Tomasz Sozański & Paweł Szpot. (2017) Nonfatal and fatal intoxications with pure caffeine – report of three different cases. Forensic Science, Medicine and Pathology 13:3, pages 355-358.
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提嶋 久子 (Hisako Sageshima)藤田 友嗣 (Yuji Fujita)牧瀬 博 (Hiroshi Makise)丸藤 哲 (Satoshi Gando). (2017) 血液透析療法により救命できた致死的カフェイン中毒(Successful treatment of a fatal caffeine overdose with hemodialysis). Nihon Kyukyu Igakukai Zasshi: Journal of Japanese Association for Acute Medicine 28:2, pages 42-47.
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Ann-Jeannette Geib. 2017. Critical Care Toxicology. Critical Care Toxicology 883 904 .
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Nathan B. Menke, Steven J. Walsh & Andrew M. King. (2015) Cardiotoxicodynamics. Emergency Medicine Clinics of North America 33:3, pages 563-595.
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Matous Schmidt, Hana Farna, Ivana Kurcova, Sergey Zakharov, Michal Fric, Petr Waldauf, Zuzana Ilgova, Jaroslav Pazout, Jan Pachl & Frantisek Duska. (2015) Succesfull treatment of supralethal caffeine overdose with a combination of lipid infusion and dialysis. The American Journal of Emergency Medicine 33:5, pages 738.e5-738.e7.
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Steven E. Meredith & Roland R. Griffiths. 2015. Psychiatry. Psychiatry 1435 1457 .
Sahand Rahnama-Moghadam, L. David Hillis & Richard A. Lange. 2015. Heart and Toxins. Heart and Toxins 75 132 .
Li Yan, Yi Huang & Shu-sheng Li. (2014) Cardiac arrest: a case-based review. World Journal of Emergency Medicine 5:3, pages 171.
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Sayaka Ishigaki, Hirotaka Fukasawa, Naoko Kinoshita-Katahashi, Hideo Yasuda, Hiromichi Kumagai & Ryuichi Furuya. (2014) Caffeine Intoxication Successfully Treated by Hemoperfusion and Hemodialysis. Internal Medicine 53:23, pages 2745-2747.
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Christina Campana, Peter L. Griffin & Erin L. Simon. (2014) Caffeine overdose resulting in severe rhabdomyolysis and acute renal failure. The American Journal of Emergency Medicine 32:1, pages 111.e3-111.e4.
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C.P. Holstege & E. Holstege. 2014. Encyclopedia of Toxicology. Encyclopedia of Toxicology 617 620 .
Mathias Poussel, Antoine Kimmoun, Bruno Levy, Nicolas Gambier, Frederic Dudek, Emmanuel Puskarczyk, Jean-Fran?ois Poussel & Bruno Chenuel. (2013) Fatal cardiac arrhythmia following voluntary caffeine overdose in an amateur body-builder athlete. International Journal of Cardiology 166:3, pages e41-e42.
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Youichi Nishimura, Takashi Iwamura, Hiroyuki Koami, Tomoko Yamashita, Atushi Nakashima, Satoshi Inoue & Yuichiro Sakamoto. (2013) A case of caffeine overdose successfully treated with hemodialysis. Nihon Kyukyu Igakukai Zasshi 24:9, pages 787-792.
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Donald G. Barceloux. 2012. Medical Toxicology of Drug Abuse. Medical Toxicology of Drug Abuse 788 804 .
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Rahi Kapur & Michael D. Smith. (2009) Treatment of cardiovascular collapse from caffeine overdose with lidocaine, phenylephrine, and hemodialysis. The American Journal of Emergency Medicine 27:2, pages 253.e3-253.e6.
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Kavita M. Babu, Richard James Church & William Lewander. (2008) Energy Drinks: The New Eye-Opener For Adolescents. Clinical Pediatric Emergency Medicine 9:1, pages 35-42.
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Davide Bolignano, Giuseppe Coppolino, Antonio Barillà, Susanna Campo, Manila Criseo, Donatella Tripodo & Michele Buemi. (2007) Caffeine and the Kidney: What Evidence Right Now?. Journal of Renal Nutrition 17:4, pages 225-234.
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William KernsIIII. (2007) Management of β-Adrenergic Blocker and Calcium Channel Antagonist Toxicity. Emergency Medicine Clinics of North America 25:2, pages 309-331.
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