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Research Article

Unusual D‐Lactic Acid Acidosis from Propylene Glycol Metabolism in Overdose

, M.D., Ph.D., , M.D., , Ph.D., , Ph.D., , M.D., Ph.D., , M.D., Ph.D. & , M.D., Ph.D. show all
Pages 163-169 | Received 25 Mar 2003, Accepted 19 Nov 2003, Published online: 05 Nov 2004

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Michael D Levitt & David G Levitt. (2020) Quantitative Evaluation of D-Lactate Pathophysiology: New Insights into the Mechanisms Involved and the Many Areas in Need of Further Investigation. Clinical and Experimental Gastroenterology 13, pages 321-337.
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Johann Lavoisier, Claire Boulle-Geronimi & Bruno Mégarbane. (2016) Fatality associated with propylene glycol poisoning in a cirrhotic patient. Clinical Toxicology 54:5, pages 462-463.
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Alex F. Manini, Ashish Kumar, Dean Olsen, David Vlahov & Robert S. Hoffman. (2010) Utility of serum lactate to predict drug-overdose fatality. Clinical Toxicology 48:7, pages 730-736.
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Philippe G. Jorens. (2009) Falsely elevated lactate and ethylene glycol. Clinical Toxicology 47:7, pages 691-691.
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Articles from other publishers (58)

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Anand Achanti & Harold M. Szerlip. (2023) Acid-Base Disorders in the Critically Ill Patient. Clinical Journal of the American Society of Nephrology 18:1, pages 102-112.
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Alluru S. ReddiAlluru S. Reddi. 2023. Fluid, Electrolyte and Acid-Base Disorders. Fluid, Electrolyte and Acid-Base Disorders 461 467 .
Xuelian Liu, Yu Zhang, Wei Li & Xin Zhou. (2022) Lactylation, an emerging hallmark of metabolic reprogramming: Current progress and open challenges. Frontiers in Cell and Developmental Biology 10.
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Viviane Van Hoof, Suzanne Bench, Antonio Buño Soto, Peter P. Luppa, Anthony Malpass, Ulf Martin Schilling, Kevin D. Rooney, Adam Stretton & Andrei N. Tintu. (2022) Failure Mode and Effects Analysis (FMEA) at the preanalytical phase for POCT blood gas analysis: proposal for a shared proactive risk analysis model. Clinical Chemistry and Laboratory Medicine (CCLM) 60:8, pages 1186-1201.
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Michael Emmett. (2022) Review of Clinical Disorders Causing Metabolic Acidosis. Advances in Chronic Kidney Disease 29:4, pages 355-363.
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Fanny de Landsheere, Franck Saint-Marcoux, Vincent Haufroid, Sylvain Dulaurent, Joseph P. Dewulf, Lidvine Boland, Pierre-François Laterre & Philippe Hantson. (2022) Unexplained Metabolic Acidosis: Alcoholic Ketoacidosis or Propylene Glycol Toxicity. Journal of Medical Toxicology 18:2, pages 155-158.
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Carolina Manosalva, John Quiroga, Alejandra I. Hidalgo, Pablo Alarcón, Nicolás Anseoleaga, María Angélica Hidalgo & Rafael Agustín Burgos. (2022) Role of Lactate in Inflammatory Processes: Friend or Foe. Frontiers in Immunology 12.
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Vladimír Podušel, Simona Morgošová, Pavol Majdák & Jurina Sadloňová. (2021) D-lactic acidosis - a rare complication of short bowel syndrome. Vnitřní lékařství 67:5, pages e28-e33.
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Hend S. Eisa, Mahmoud A. Nomier, Manar H. Arafa & Eman El-Sayed Khayal. (2021) Predictors of Severity and Survival in Acute Cases of Organophosphorous Poisoning at Zagazig University Hospitals: Prospective Cohort Study. Toxicology International, pages 185-201.
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Konstantinos Farsalinos. 2021. Toxicological Risk Assessment and Multi-System Health Impacts from Exposure. Toxicological Risk Assessment and Multi-System Health Impacts from Exposure 617 643 .
Matthias Weemaes, Martin Hiele & Pieter Vermeersch. (2019) High anion gap metabolic acidosis caused by D-lactate: mind the time of blood collection. Biochemia Medica 30:1.
Crossref
Gabriel Wardi, Jessica Brice, Matthew Correia, Dennis Liu, Michael Self & Christopher Tainter. (2020) Demystifying Lactate in the Emergency Department. Annals of Emergency Medicine 75:2, pages 287-298.
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Glen R. Monroe, Albertien M. van Eerde, Federico Tessadori, Karen J. Duran, Sanne M. C. Savelberg, Johanna C. van Alfen, Paulien A. Terhal, Saskia N. van der Crabben, Klaske D. Lichtenbelt, Sabine A. Fuchs, Johan Gerrits, Markus J. van Roosmalen, Koen L. van Gassen, Mirjam van Aalderen, Bart G. Koot, Marlies Oostendorp, Marinus Duran, Gepke Visser, Tom J. de Koning, Francesco Calì, Paolo Bosco, Karin Geleijns, Monique G. M. de Sain-van der Velden, Nine V. Knoers, Jeroen Bakkers, Nanda M. Verhoeven-Duif, Gijs van Haaften & Judith J. Jans. (2019) Identification of human D lactate dehydrogenase deficiency. Nature Communications 10:1.
Crossref
David H. Jelley, Deborah Zayneb Mohamad Ali & Michelle Condren. (2019) Acute Renal Failure Secondary to Inadvertent Propylene Glycol Overdose with Single-Day High-Dose Vitamin D (Stosstherapy). Case Reports in Endocrinology 2019, pages 1-3.
Crossref
Manpreet S. Mundi, Aravind Reddy Kuchkuntla & Ryan T. Hurt. 2019. Adult Short Bowel Syndrome. Adult Short Bowel Syndrome 109 127 .
Sorin Stanciu & Aminda De Silva. (2018) Metabolic acidosis in short bowel syndrome: think D-lactic acid acidosis. BMJ Case Reports, pages bcr-2018-224221.
Crossref
Davide G. A. M. Bianchetti, Giacomo S. Amelio, Sebastiano A. G. Lava, Mario G. Bianchetti, Giacomo D. Simonetti, Carlo Agostoni, Emilio F. Fossali & Gregorio P. Milani. (2017) D-lactic acidosis in humans: systematic literature review. Pediatric Nephrology 33:4, pages 673-681.
Crossref
Jeffrey A. KrautMichael E. Mullins. (2018) Toxic Alcohols. New England Journal of Medicine 378:3, pages 270-280.
Crossref
Amy Wallis, Michelle Ball, Sandra McKechnie, Henry Butt, Donald P. Lewis & Dorothy Bruck. (2017) Examining clinical similarities between myalgic encephalomyelitis/chronic fatigue syndrome and d-lactic acidosis: a systematic review. Journal of Translational Medicine 15:1.
Crossref
H. Arafa Manar, M. Shalaby Nashwa & H. Atteia Hebatallah. (2017) Lactate and creatine phosphokinase as potential independent predictors of organophosphrus poisoning severity in Zagazig University Hospital Patients, Egypt. Journal of Toxicology and Environmental Health Sciences 9:8, pages 73-82.
Crossref
Peyman Erfantalab, Kambiz Soltaninejad, Shahin Shadnia, Nasim Zamani, Hossein Hassanian-Moghaddam, Arezou Mahdavinejad & Behrooz Hashemi Damaneh. (2017) Trend of blood lactate level in acute aluminum phosphide poisoning. World Journal of Emergency Medicine 8:2, pages 116.
Crossref
K.E. Farsalinos. 2017. Analytical Assessment of E-Cigarettes. Analytical Assessment of E-Cigarettes 75 122 .
Knut Erik Hovda, Kenneth McMartin & Dag Jacobsen. 2017. Critical Care Toxicology. Critical Care Toxicology 1743 1760 .
Stephen W. Borron. 2017. Critical Care Toxicology. Critical Care Toxicology 325 358 .
Anne Garat, Patrick Nisse, Marie Kauv, Monique Mathieu-Nolf, Delphine Allorge & Daniel Mathieu. (2016) Lactic acidosis due to voluntary e-liquid ingestion. Toxicologie Analytique et Clinique 28:4, pages 329-332.
Crossref
. 2016. Meyler's Side Effects of Drugs. Meyler's Side Effects of Drugs 567 570 .
Knut Erik Hovda, Kenneth McMartin & Dag Jacobsen. 2016. Critical Care Toxicology. Critical Care Toxicology 1 18 .
Stephen W. Borron. 2016. Critical Care Toxicology. Critical Care Toxicology 1 34 .
Thomas D. DuBose. 2016. Metabolic Acidosis. Metabolic Acidosis 27 38 .
Thomas D. DuBose. 2016. Metabolic Acidosis. Metabolic Acidosis 17 26 .
Janna H. Villano, Charles W. O’Connell, Binh T. Ly & Aaron Schneir. (2015) Case Files from the University of California San Diego Health System Fellowship Coma and Severe Acidosis: Remember to Consider Acetaminophen. Journal of Medical Toxicology 11:3, pages 368-376.
Crossref
Brian Park, Utkarsh Fichadia & Ami Shah. (2015) A 3-Year-Old Boy With Ataxia. Pediatric Emergency Care 31:3, pages 220-221.
Crossref
N. Gurukripa Kowlgi & Lovely Chhabra. (2015) D-Lactic Acidosis: An Underrecognized Complication of Short Bowel Syndrome. Gastroenterology Research and Practice 2015, pages 1-8.
Crossref
Stephen W. Borron. 2016. Critical Care Toxicology. Critical Care Toxicology 1 34 .
M. Adeva-Andany, M. López-Ojén, R. Funcasta-Calderón, E. Ameneiros-Rodríguez, C. Donapetry-García, M. Vila-Altesor & J. Rodríguez-Seijas. (2014) Comprehensive review on lactate metabolism in human health. Mitochondrion 17, pages 76-100.
Crossref
Nalini N.E. Radhakishun, Mariska van Vliet, Dennis C.W. Poland, Olivier Weijer, Jos H. Beijnen, Dees P.M. Brandjes, Michaela Diamant & Ines A. von Rosenstiel. (2014) Efficacy and Tolerability of a High Loading Dose (25,000 IU Weekly) Vitamin D<sub>3</sub> Supplementation in Obese Children with Vitamin D Insufficiency/Deficiency. Hormone Research in Paediatrics 82:2, pages 103-106.
Crossref
María M. Adeva-Andany, Natalia Carneiro-Freire, Cristóbal Donapetry-García, Eva Rañal-Muíño & Yosua López-Pereiro. (2014) The Importance of the Ionic Product for Water to Understand the Physiology of the Acid-Base Balance in Humans. BioMed Research International 2014, pages 1-16.
Crossref
O. Onofrei, V. Haufroid, J. -P. Goulle, A. Penaloza Baeza & P. Hantson. (2012) Coma toxique et acidose métabolique inexpliquée chez une patiente éthylique chroniqueToxic coma with unexplained metabolic acidosis in a chronic ethanol abuser. Annales françaises de médecine d'urgence 3:2, pages 126-128.
Crossref
. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 29 .
. 2002. The MAK-Collection for Occupational Health and Safety. The MAK-Collection for Occupational Health and Safety 1 318 .
Antonietta Gigante, Liborio Sardo, Maria Ludovica Gasperini, Antonio Molinaro, Oliviero Riggio, Alessandro Laviano & Antonio Amoroso. (2012) D-Lactic acidosis 25 years after bariatric surgery due to Salmonella enteritidis. Nutrition 28:1, pages 108-111.
Crossref
Thomas D. DuBoseJr.Jr.. 2012. Brenner and Rector's The Kidney. Brenner and Rector's The Kidney 595 639 .
Melissa A. Claus, Karl E. Jandrey & Robert H. Poppenga. (2011) Propylene glycol intoxication in a dog. Journal of Veterinary Emergency and Critical Care 21:6, pages 679-683.
Crossref
Colleen B. Kjelland & Dennis Djogovic. (2010) The Role of Serum Lactate in the Acute Care Setting. Journal of Intensive Care Medicine 25:5, pages 286-300.
Crossref
Ming-Tso Yan, Tom Chau, Chih-Jen Cheng & Shih-Hua Lin. (2010) Hunting down a double gap metabolic acidosis. Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 47:3, pages 267-270.
Crossref
Qing H. Meng, Khosrow Adeli, Gordon A. Zello, William H. Porter & John Krahn. (2010) Elevated lactate in ethylene glycol poisoning: True or false?. Clinica Chimica Acta 411:7-8, pages 601-604.
Crossref
John A. Kellum. (2008) Acid-base balance. Critical Care Medicine 36:5, pages 1691.
Crossref
Jeffrey A. Kraut & Ira Kurtz. (2008) Toxic Alcohol Ingestions: Clinical Features, Diagnosis, and Management. Clinical Journal of the American Society of Nephrology 3:1, pages 208-225.
Crossref
Thomas D. DuBoseJr.Jr.. 2008. Therapy in Nephrology & Hypertension. Therapy in Nephrology & Hypertension 368 380 .
Tausif Zar, Irfan Yusufzai, Anna Sullivan & Charles Graeber. (2007) Acute kidney injury, hyperosmolality and metabolic acidosis associated with lorazepam. Nature Clinical Practice Nephrology 3:9, pages 515-520.
Crossref
Saman Abeysekara, Jonathan M. Naylor, Andrew W. A. Wassef, Ulyana Isak & Gordon A. Zello. (2007) d -Lactic acid-induced neurotoxicity in a calf model . American Journal of Physiology-Endocrinology and Metabolism 293:2, pages E558-E565.
Crossref
. 2007. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose 13 61 .
Juha Laitinen, Jyrki Liesivuori & Rauno Harvima. (2006) Evaluation of exposure to 1-alkoxy-2-propanols and 1-(2-methoxy-1-methylethoxy)-2-propanol by the analysis of the parent compounds in urine. Toxicology Letters 162:2-3, pages 186-194.
Crossref
. 2006. Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions. Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions 1516 .
Craig Petersen. (2017) D-Lactic Acidosis. Nutrition in Clinical Practice 20:6, pages 634-645.
Crossref

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