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Research Article

Acute Human Self‐Poisoning with the N‐Phenylpyrazole Insecticide Fipronil—a GABAA‐Gated Chloride Channel Blocker

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Pages 955-963 | Published online: 12 Sep 2004

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Thilini Madushanka Wijerathna, Indika Bandara Gawarammana, Dhammika Menike Dissanayaka, Chathura Palanagasinghe, Fathima Shihana, Gihani Dassanayaka, Seyed Shahmy, Zoltan Huba Endre, Fahim Mohamed & Nicholas Alan Buckley. (2017) Serum creatinine and cystatin C provide conflicting evidence of acute kidney injury following acute ingestion of potassium permanganate and oxalic acid. Clinical Toxicology 55:9, pages 970-976.
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Xu Wang, María Aránzazu Martínez, Qinghua Wu, Irma Ares, María Rosa Martínez-Larrañaga, Arturo Anadón & Zonghui Yuan. (2016) Fipronil insecticide toxicology: oxidative stress and metabolism. Critical Reviews in Toxicology 46:10, pages 876-899.
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Melinda Bigelow Dyk, Yu Liu, Zhenshan Chen, Helen Vega & RobertI. Krieger. (2012) Fate and distribution of fipronil on companion animals and in their indoor residences following spot-on flea treatments. Journal of Environmental Science and Health, Part B 47:10, pages 913-924.
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Soo-Jeong Lee, Prakash Mulay, Brienne Diebolt-Brown, Michelle J. Lackovic, Louise N. Mehler, John Beckman, Justin Waltz, Joanne B. Prado, Yvette A. Mitchell, Sheila A. Higgins, Abby Schwartz & Geoffrey M. Calvert. (2010) Acute illnesses associated with exposure to fipronil—surveillance data from 11 states in the United States, 2001–2007. Clinical Toxicology 48:7, pages 737-744.
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MatthewC. Keifer & Jordan Firestone. (2007) Neurotoxicity of Pesticides. Journal of Agromedicine 12:1, pages 17-25.
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Ya-Ning Chang & Tung-Hu Tsai. (2020) Preclinical Transplacental Transfer and Pharmacokinetics of Fipronil in Rats. Drug Metabolism and Disposition 48:10, pages 886-893.
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Pietro Gerletti, Max Von Kleist, Hans Mielke, Thomas Kuhl, Robert Pieper, Monika Lahrssen-Wiederholt & Jorge Numata. (2020) Transfer kinetics of fipronil into chicken (Gallus gallus domesticus) eggs. Computational Toxicology 15, pages 100131.
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A.A. Khalaf, Mona K. Galal, Marwa A. Ibrahim, A.A. Abd Allah, Mostafa M. Afify & Rasha Refaat. (2019) The Terminalia laxiflora modulates the neurotoxicity induced by fipronil in male albino rats . Bioscience Reports 39:3.
Crossref
Kai Wang, Natalia Vasylieva, Debin Wan, David A. Eads, Jun Yang, Tyler Tretten, Bogdan Barnych, Ji Li, Qing X. Li, Shirley J. Gee, Bruce D. Hammock & Ting Xu. (2018) Quantitative Detection of Fipronil and Fipronil-Sulfone in Sera of Black-Tailed Prairie Dogs and Rats after Oral Exposure to Fipronil by Camel Single-Domain Antibody-Based Immunoassays. Analytical Chemistry 91:2, pages 1532-1540.
Crossref
Smitesh Gutta, JohnD Prasad, Karthik Gunasekaran & Ramya Iyadurai. (2019) Hepatotoxicity and neurotoxicity of Fipronil poisoning in human: A case report. Journal of Family Medicine and Primary Care 8:10, pages 3437.
Crossref
Deon van der MerweAnnemiek JordaanMartin van den Berg. 2019. Chemical hazards in foods of animal origin. Chemical hazards in foods of animal origin 567 584 .
Rania Abdelrahman Elgawish, Heba M. A. Abdelrazek, Shimaa A. A. Ismail, Naglaa M. Loutfy & Mohamed T. A. Soliman. (2018) Hepatoprotective activity of Uncaria tomentosa extract against sub-chronic exposure to fipronil in male rats. Environmental Science and Pollution Research 26:1, pages 199-207.
Crossref
Dong Jae Kim, Sung-Gyu Park, Dong-Ho Kim & Shin-Hyun Kim. (2018) SERS-Active-Charged Microgels for Size- and Charge-Selective Molecular Analysis of Complex Biological Samples. Small 14:40, pages 1802520.
Crossref
Mohamed M. Abdel-Daim, Hazem M. Shaheen, Abdelrahman Ibrahim Abushouk, Eman A. Toraih, Manal S. Fawzy, Wafa S. Alansari, Lotfi Aleya & Simona Bungau. (2018) Thymoquinone and diallyl sulfide protect against fipronil-induced oxidative injury in rats. Environmental Science and Pollution Research 25:24, pages 23909-23916.
Crossref
Morgane Cam, Emilie Durieu, Marion Bodin, Antigoni Manousopoulou, Svenja Koslowski, Natalia Vasylieva, Bogdan Barnych, Bruce D. Hammock, Bettina Bohl, Philipp Koch, Chiori Omori, Kazuo Yamamoto, Saori Hata, Toshiharu Suzuki, Frank Karg, Patrick Gizzi, Vesna Erakovic Haber, Vlatka Bencetic Mihaljevic, Branka Tavcar, Erik Portelius, Josef Pannee, Kaj Blennow, Henrik Zetterberg, Spiros D. Garbis, Pierrick Auvray, Hermeto Gerber, Jeremy Fraering, Patrick C. Fraering & Laurent Meijer. (2018) Induction of Amyloid-β42 Production by Fipronil and Other Pyrazole Insecticides. Journal of Alzheimer's Disease 62:4, pages 1663-1681.
Crossref
Ka Hong & Letha Sooter. (2017) In Vitro Selection of a Single-Stranded DNA Molecular Recognition Element against the Pesticide Fipronil and Sensitive Detection in River Water. International Journal of Molecular Sciences 19:1, pages 85.
Crossref
Robert D. Mitchell III, Andrew D. Wallace, Ernest Hodgson & R. Michael Roe. (2017) Differential Expression Profile of lncRNAs from Primary Human Hepatocytes Following DEET and Fipronil Exposure. International Journal of Molecular Sciences 18:10, pages 2104.
Crossref
Natalia Vasylieva, Bogdan Barnych, Debin Wan, El-Sayed A. El-Sheikh, Hai M. Nguyen, Heike Wulff, Rebecca McMahen, Mark Strynar, Shirley J. Gee & Bruce D. Hammock. (2017) Hydroxy-fipronil is a new urinary biomarker of exposure to fipronil. Environment International 103, pages 91-98.
Crossref
Theetat Ruangjaroon, Daranee Chokchaichamnankit, Chantragan Srisomsap, Jisnuson Svasti & N. Monique Paricharttanakul. (2017) Involvement of vimentin in neurite outgrowth damage induced by fipronil in SH-SY5Y cells. Biochemical and Biophysical Research Communications 486:3, pages 652-658.
Crossref
Samah R. Khalil, Ashraf Awad & Hesham H. Mohammed. (2017) Behavioral response and gene expression changes in fipronil-administered male Japanese quail (Coturnix japonica). Environmental Pollution 223, pages 51-61.
Crossref
Liane Ziliotto, Stelio P.L. Luna, Daniel A. A.Filho, Ludimila O. Resende, Aline G. Aun & Mariana G. Braz. (2017) Genotoxicity assessment of fipronil (frontline plus®) in Canis familiaris. Pesquisa Veterinária Brasileira 37:3, pages 257-260.
Crossref
Katharina Kuenzel, Sepideh Abolpour Mofrad & Daniel F. Gilbert. 2017. Cell Viability Assays. Cell Viability Assays 205 214 .
Katharina Kuenzel, Oliver Friedrich & Daniel F. Gilbert. (2016) A Recombinant Human Pluripotent Stem Cell Line Stably Expressing Halide-Sensitive YFP-I152L for GABAAR and GlyR-Targeted High-Throughput Drug Screening and Toxicity Testing. Frontiers in Molecular Neuroscience 9.
Crossref
A. Romero, E. Ramos, I. Ares, V. Castellano, M. Martínez, M.R. Martínez-Larrañaga, A. Anadón & M.A. Martínez. (2016) Fipronil sulfone induced higher cytotoxicity than fipronil in SH-SY5Y cells: Protection by antioxidants. Toxicology Letters 252, pages 42-49.
Crossref
Quancai Sun, Weipeng Qi, Jeremy J. Yang, Kyong Sup Yoon, John M. Clark & Yeonhwa Park. (2016) Fipronil promotes adipogenesis via AMPK?-mediated pathway in 3T3-L1 adipocytes. Food and Chemical Toxicology 92, pages 217-223.
Crossref
Hsien-Yi Chen, Timothy E. Albertson & Kent R. Olson. (2016) Treatment of drug-induced seizures. British Journal of Clinical Pharmacology 81:3, pages 412-419.
Crossref
Michael Eddleston. (2016) Pesticides. Medicine 44:3, pages 193-196.
Crossref
Joao Leandro Chaguri, Antonio Francisco Godinho, Daniel França Horta, Victor Hugo Gonçalves-Rizzi, Jose Sergio Possomato-Vieira, Regina Aparecida Nascimento & Carlos Alan Dias-Junior. (2016) Exposure to fipronil elevates systolic blood pressure and disturbs related biomarkers in plasma of rats. Environmental Toxicology and Pharmacology 42, pages 63-68.
Crossref
Marieli Guelfi, Marcos Antonio Maioli, Marco Aurélio Tavares & Fábio Erminio Mingatto. (2015) Citotoxicity of Fipronil on Hepatocytes Isolated from Rat and Effects of Its Biotransformation. Brazilian Archives of Biology and Technology 58:6, pages 843-853.
Crossref
Julia Z. Magalh?es, Mariana S.B. Udo, Ang?lica M. S?nchez-Sarmiento, Marcelo P.N. Carvalho, Maria M. Bernardi & Helenice S. Spinosa. (2015) Prenatal exposure to fipronil disturbs maternal aggressive behavior in rats. Neurotoxicology and Teratology 52, pages 11-16.
Crossref
M.V. Caballero, I. Ares, M. Martínez, M.R. Martínez-Larrañaga, A. Anadón & M.A. Martínez. (2015) Fipronil induces CYP isoforms in rats. Food and Chemical Toxicology 83, pages 215-221.
Crossref
Natalia Vasylieva, Ki Chang Ahn, Bogdan Barnych, Shirley J. Gee & Bruce D. Hammock. (2015) Development of an Immunoassay for the Detection of the Phenylpyrazole Insecticide Fipronil. Environmental Science & Technology 49:16, pages 10038-10047.
Crossref
Hyllana Catarine Dias de Medeiros, Jorgete Constantin, Emy Luiza Ishii-Iwamoto & Fábio Erminio Mingatto. (2015) Effect of fipronil on energy metabolism in the perfused rat liver. Toxicology Letters 236:1, pages 34-42.
Crossref
Rebecca L. McMahen, Mark J. Strynar, Sonia Dagnino, David W. Herr, Virginia C. Moser, Stavros Garantziotis, Erik M. Andersen, Danielle L. Freeborn, Larry McMillan & Andrew B. Lindstrom. (2015) Identification of fipronil metabolites by time-of-flight mass spectrometry for application in a human exposure study. Environment International 78, pages 16-23.
Crossref
Insaf Ayadi, Sandra Mariza Monteiro, Imed Regaya, Ana Coimbra, Fontainhas Fernandes, Maria Manuel Oliveira, Francisco Peixoto & Wissem Mnif. (2015) Biochemical and histological changes in the liver and gills of Nile tilapia Oreochromis niloticus exposed to Red 195 dye. RSC Advances 5:106, pages 87168-87178.
Crossref
Abdel-Tawab H. Mossa, Eman S. Swelam & Samia M.M. Mohafrash. (2015) Sub-chronic exposure to fipronil induced oxidative stress, biochemical and histopathological changes in the liver and kidney of male albino rats. Toxicology Reports 2, pages 775-784.
Crossref
Danielle L. Freeborn, Katherine L. McDaniel, Virginia C. Moser & David W. Herr. (2015) Use of electroencephalography (EEG) to assess CNS changes produced by pesticides with different modes of action: Effects of permethrin, deltamethrin, fipronil, imidacloprid, carbaryl, and triadimefon. Toxicology and Applied Pharmacology 282:2, pages 184-194.
Crossref
Michael D. Coleman. 2014. Expert Report Writing in Toxicology. Expert Report Writing in Toxicology 123 178 .
Hisao Hidaka, Tohru Tsukamoto, Yoshihiro Mitsutsuka, Takeji Takamura & Nick Serpone. (2014) Photochemical and Ga 2 O 3 -photoassisted decomposition of the insecticide Fipronil in aqueous media upon UVC radiation . New J. Chem. 38:8, pages 3939-3952.
Crossref
J.P. Cravedi, G. Delous, D. Zalko, C. Viguié & L. Debrauwer. (2013) Disposition of fipronil in rats. Chemosphere 93:10, pages 2276-2283.
Crossref
Kevin Woodward & Kevin WoodwardK. N. Woodward. 2012. Toxicological Effects of Veterinary Medicinal Products in Humans. Toxicological Effects of Veterinary Medicinal Products in Humans 150 243 .
R. Flores-Ramírez, L. E. Batres-Esquivel, F. Díaz-Barriga Martínez, I. López-Acosta & M. D. Ortiz-Pérez. (2012) Development and Validation of an Analytical Method to Determine Fipronil and its Degradation Products in Soil Samples. Bulletin of Environmental Contamination and Toxicology 89:4, pages 744-750.
Crossref
B?atrice B. Roques, Marl?ne Z. Lacroix, Sylvie Puel, V?ronique Gayrard, Nicole Picard-Hagen, Isabelle Jouanin, Elisabeth Perdu, Pascal G. Martin & Catherine Vigui?. (2012) CYP450-Dependent Biotransformation of the Insecticide Fipronil into Fipronil Sulfone Can Mediate Fipronil-Induced Thyroid Disruption in Rats. Toxicological Sciences 127:1, pages 29-41.
Crossref
Robiul Islam & Joseph W Lynch. (2012) Mechanism of action of the insecticides, lindane and fipronil, on glycine receptor chloride channels. British Journal of Pharmacology 165:8, pages 2707-2720.
Crossref
K N Woodward. 2012. Mammalian Toxicology of Insecticides. Mammalian Toxicology of Insecticides 348 426 .
Atsushi Suzuki, Ayumi Aoki, Masami Fujiwara, Osamu Koto, Masako Akiyama, Atsushi Suzuki, Ayumi Aoki, Masami Fujiwara, Osamu Koto & Masako Akiyama. (2012) GABA A receptor antagonistic insecticide fipronil: Overview of toxicological studies. Journal of Pesticide Science 37:4, pages 349-361.
Crossref
Laurence Murillo, Alain Hamon, Zeineb Es-Salah-Lamoureux, Val?rie Itier, Sophie Quinchard & Bruno Lapied. (2011) Inhibition of protein kinase C decreases sensitivity of GABA receptor subtype to fipronil insecticide in insect neurosecretory cells. NeuroToxicology 32:6, pages 828-835.
Crossref
Cyril Vidau, Rosa A. González-Polo, Mireia Niso-Santano, Rubén Gómez-Sánchez, José M. Bravo-San Pedro, Elisa Pizarro-Estrella, Rafael Blasco, Jean-Luc Brunet, Luc P. Belzunces & José M. Fuentes. (2011) Fipronil is a powerful uncoupler of oxidative phosphorylation that triggers apoptosis in human neuronal cell line SHSY5Y. NeuroToxicology 32:6, pages 935-943.
Crossref
Fabrice HerinElisa Boutet-RobinetAude LevantSylvain DulaurentMimoza ManikaFlorence Galatry-BoujuPhilippe CaronJean-Marc Soulat. (2011) Thyroid Function Tests in Persons with Occupational Exposure to Fipronil. Thyroid 21:7, pages 701-706.
Crossref
Julien Leghait, Véronique Gayrard, Pierre-Louis Toutain, Nicole Picard-Hagen & Catherine Viguié. (2010) Is the mechanisms of fipronil-induced thyroid disruption specific of the rat: Re-evaluation of fipronil thyroid toxicity in sheep?. Toxicology Letters 194:3, pages 51-57.
Crossref
Ian C. Dewhurst & Timothy C. Marrs. 2009. General and Applied Toxicology. General and Applied Toxicology.
Julien Leghait, V?ronique Gayrard, Nicole Picard-Hagen, Marion Camp, Elisabeth Perdu, Pierre-Louis Toutain & Catherine Vigui?. (2009) Fipronil-induced disruption of thyroid function in rats is mediated by increased total and free thyroxine clearances concomitantly to increased activity of hepatic enzymes. Toxicology 255:1-2, pages 38-44.
Crossref
P Li & G Akk. (2008) The insecticide fipronil and its metabolite fipronil sulphone inhibit the rat α1β2γ2L GABA A receptor . British Journal of Pharmacology 155:5, pages 783-794.
Crossref
Darren M Roberts & Nick A Buckley. (2007) Pharmacokinetic Considerations in Clinical Toxicology. Clinical Pharmacokinetics 46:11, pages 897-939.
Crossref
F. Testud & J.-P. Grillet. (2007) Insecticides organophosphorés, carbamates, pyréthrinoïdes de synthèse et divers. EMC - Pathologie professionnelle et de l 'environnement 2:2, pages 1-24.
Crossref
STEPHEN W. BORRON. 2007. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose 1185 1194 .
Ali Kadar & Jean-Paul Faucon. (2006) Determination of Traces of Fipronil and Its Metabolites in Pollen by Liquid Chromatography with Electrospray Ionization−Tandem Mass Spectrometry. Journal of Agricultural and Food Chemistry 54:26, pages 9741-9746.
Crossref
Nick A Buckley, Michael Eddleston & Andrew H Dawson. (2005) The need for translational research on antidotes for pesticide poisoning. Clinical and Experimental Pharmacology and Physiology 32:11, pages 999-1005.
Crossref

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