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Research Article

Ciprofloxacin‐Induced Glutathione Redox Status Alterations in Rat Tissues

, Ph.D. &
Pages 233-242 | Published online: 29 Jul 2004

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Abeer Salama, Hend Abd-AlHakim Mahmoud, Mohamed Ahmed Kandeil & Marwa Mahmoud Khalaf. (2021) Neuroprotective role of camphor against ciprofloxacin induced depression in rats: modulation of Nrf-2 and TLR4. Immunopharmacology and Immunotoxicology 43:3, pages 309-318.
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Majed M Masadeh, Karem H Alzoubi, Bashar M Al-Taani, Majd M Masadeh, Zainah O Aburashed & Nasr Alrabadi. (2020) Vitamin D Pretreatment Attenuates Ciprofloxacin-Induced Antibacterial Activity. Clinical Pharmacology: Advances and Applications 12, pages 171-176.
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Aylin Gürbay, Brigitte Gonthier, Denis Daveloose, Luc Barret, Alain Favier & Filiz Hıncal. (2019) Ciprofloxacin-induces free radical production in rat cerebral microsomes. Free Radical Research 53:4, pages 397-404.
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Majed M Masadeh, Karem H Alzoubi, Sayer I Al-azzam & Ahlam M Al-buhairan. (2017) Possible involvement of ROS generation in vorinostat pretreatment induced enhancement of the antibacterial activity of ciprofloxacin. Clinical Pharmacology: Advances and Applications 9, pages 119-124.
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Damon A. Lowes, Carol Wallace, Michael P. Murphy, Nigel R. Webster & Helen F. Galley. (2009) The mitochondria targeted antioxidant MitoQ protects against fluoroquinolone-induced oxidative stress and mitochondrial membrane damage in human Achilles tendon cells. Free Radical Research 43:4, pages 323-328.
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Aylin Gürbay, Mireille Osman, Alain Favier & Filiz Hincal. (2005) Ciprofloxacin-Induced Cytotoxicity and Apoptosis in HeLa Cells. Toxicology Mechanisms and Methods 15:5, pages 339-342.
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Asieh Davary Avareshk, Razieh Jalal & Jamileh Gholami. (2022) The effect of ciprofloxacin on doxorubicin cytotoxic activity in the acquired resistance to doxorubicin in DU145 prostate carcinoma cells. Medical Oncology 39:12.
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Nehad M. Abd-elmonsif, Medhat A. El-Zainy, Amany A. Rabea & Iman A. Fathy Mohamed. (2022) The Prospective Effect of Cinnamon and Chia on Submandibular Salivary Glands After Ciprofloxacin Administration in Albino Rats (Histological, Histochemical, and Ultrastructural Study). Microscopy and Microanalysis, pages 1-18.
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Hovhannes J. Gukasyan & Richard Graham. 2021. Ophthalmic Product Development. Ophthalmic Product Development 249 315 .
Ana Filipa Nogueira & Bruno Nunes. (2020) Effects of low levels of the antibiotic ciprofloxacin on the polychaete Hediste diversicolor: biochemical and behavioural effects. Environmental Toxicology and Pharmacology 80, pages 103505.
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Hesham Ahmed Khalifa, Shimaa Ibrahim Shalaby & Ahmed Shaban Abdelaziz. (2020) Alhagi maurorum aqueous extract protects against norfloxacin-induced hepato-nephrotoxicity in rats. Chinese Herbal Medicines 12:2, pages 156-162.
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Asa Motiei, Björn Brindefalk, Martin Ogonowski, Rehab El-Shehawy, Paulina Pastuszek, Karin Ek, Birgitta Liewenborg, Klas Udekwu & Elena Gorokhova. (2020) Disparate effects of antibiotic-induced microbiome change and enhanced fitness in Daphnia magna. PLOS ONE 15:1, pages e0214833.
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Pavla Sehonova, Nina Tokanova, Nikola Hodkovicova, Hana Kocour Kroupova, Jitka Tumova, Jana Blahova, Petr Marsalek, Lucie Plhalova, Veronika Doubkova, Radka Dobsikova, Petr Chloupek, Petra Dolezalova, Martin Faldyna, Zdenka Svobodova & Caterina Faggio. (2019) Oxidative stress induced by fluoroquinolone enrofloxacin in zebrafish (Danio rerio) can be ameliorated after a prolonged exposure. Environmental Toxicology and Pharmacology 67, pages 87-93.
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Rahul Parashar, Lachhman Das Singla, Mayank Gupta & Suresh Kumar Sharma. (2018) Evaluation and correlation of oxidative stress and haemato-biochemical observations in horses with natural patent and latent trypanosomosis in Punjab state of India. Acta Parasitologica 63:4, pages 733-743.
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Richard Kast, Nicolas Skuli, Iacopo Sardi, Felix Capanni, Martin Hessling, Guido Frosina, Anton Kast, Georg Karpel-Massler & Marc-Eric Halatsch. (2018) Augmentation of 5-Aminolevulinic Acid Treatment of Glioblastoma by Adding Ciprofloxacin, Deferiprone, 5-Fluorouracil and Febuxostat: The CAALA Regimen. Brain Sciences 8:12, pages 203.
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Majed Masadeh, Karem Alzoubi, Sayer Al-azzam, Omar Khabour & Ahlam Al-buhairan. (2016) Ciprofloxacin-Induced Antibacterial Activity Is Atteneuated by Pretreatment with Antioxidant Agents. Pathogens 5:1, pages 28.
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Majed M. Masadeh, Karem H. Alzoubi, Omar F. Khabour & Sayer I. Al-Azzam. (2015) Ciprofloxacin-Induced Antibacterial Activity Is Attenuated by Phosphodiesterase Inhibitors. Current Therapeutic Research 77, pages 14-17.
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Kamalpreet Kaur Gill, Harpal Singh Sandhu & Rajdeep Kaur. (2015) Evaluation of lipid peroxidation and antioxidant status on fenvalerate, nitrate and their co-exposure in Bubalus bubalis. Pesticide Biochemistry and Physiology 123, pages 19-23.
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GB Kumbhar, AM Khan & S Rampal. (2014) Evaluation of gatifloxacin for its potential to induce antioxidant imbalance and retinopathy in rabbits. Human & Experimental Toxicology 34:4, pages 372-379.
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Prashant S. Daundkar & S. Rampal. (2014) Evaluation of ameliorative potential of selenium on carbendazim induced oxidative stress in male goats. Environmental Toxicology and Pharmacology 38:3, pages 711-719.
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Sean R Marcsisin, Xiannu Jin, Theresa Bettger, Nicholas McCulley, Jason C Sousa, G Dennis Shanks, Babu L Tekwani, Rajnish Sahu, Gregory A Reichard, Richard J Sciotti, Victor Melendez & Brandon S Pybus. (2013) CYP450 phenotyping and metabolite identification of quinine by accurate mass UPLC-MS analysis: a possible metabolic link to blackwater fever. Malaria Journal 12:1.
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Rajdeep Kaur & Shabir Ahmad Dar. (2013) Comparative evaluation of oral and dermal cypermethrin exposure on antioxidant profile in Bubalus bubalis. Food and Chemical Toxicology 61, pages 121-126.
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Nadia M. S. Arafa, Mona Abdel-Rahman, Manal F. El-khadragy & Rami B. Kassab. (2012) Evaluation of the Possible Epileptogenic Activity of Ciprofloxacin: The Role of Nigella sativa on Amino Acids Neurotransmitters. Neurochemical Research 38:1, pages 174-185.
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Majed M. Masadeh, Nizar M. Mhaidat, Karem H. Alzoubi, Sayer I. Al-Azzam & Ashraf I. Shaweesh. (2012) Ciprofloxacin-Induced Antibacterial Activity is Reversed by Vitamin E and Vitamin C. Current Microbiology 64:5, pages 457-462.
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G. Y. Minuk, K. Hawkins, K. D. E. Kaita, S. Wong, E. Renner, L. Minuk & J. Uhanova. (2010) Daily Ciprofloxacin Treatment for Patients with Advanced Liver Disease Awaiting Liver Transplantation Reduces Hospitalizations. Digestive Diseases and Sciences 56:4, pages 1235-1241.
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Mederic M. Hall, Jonathan T. Finnoff & Jay Smith. (2011) Musculoskeletal Complications of Fluoroquinolones: Guidelines and Precautions for Usage in the Athletic Population. PM&R 3:2, pages 132-142.
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Tomasz Kloskowski, Natalia Gurtowska & Tomasz Drewa. (2010) Does ciprofloxacin have an obverse and a reverse?. Pulmonary Pharmacology & Therapeutics 23:5, pages 373-375.
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Lina Gunnarsson, Erik Kristiansson, Carolin Rutgersson, Joachim Sturve, Jerker Fick, Lars Förlin & D. G. Joakim Larsson. (2010) Pharmaceutical industry effluent diluted 1:500 affects global gene expression, cytochrome P450 1A activity, and plasma phosphate in fish. Environmental Toxicology and Chemistry 28:12, pages 2639-2647.
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H. Dorota Halicka, Daniel J. Smart, Frank Traganos, Gary M. Williams & Zbigniew Darzynkiewicz. (2009) Fluoroquinolones lower constitutive H2AX and ATM phosphorylation in TK6 lymphoblastoid cells via modulation of the intracellular redox status. Pharmacological Reports 61:4, pages 711-718.
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Aylin Gürbay, Brigitte Gonthier, Luc Barret, Alain Favier & Filiz Hıncal. (2007) Cytotoxic effect of ciprofloxacin in primary culture of rat astrocytes and protection by Vitamin E. Toxicology 229:1-2, pages 54-61.
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