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Drug Metabolism Reviews Volume 31, 1999 - Issue 1
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Research Article

PREDICTING DRUG INTERACTIONS AND PHARMACOKINETIC VARIABILITY WITH IN VITRO METHODS: THE OLANZAPINE EXPERIENCE*

STEVEN A. WRIGHTON Department of Drug Disposition, Lilly Research Laboratories, Lilly Corporate Center, Mail Drop 0825, Indianapolis, IN, 46285, U.S.A.
&
BARBARA J. RING
Pages 15-28 | Published online: 02 Aug 1999

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S. Sakuda, T. Akabane & T. Teramura. (2006) Marked species differences in the bioavailability of midazolam in cynomolgus monkeys and humans. Xenobiotica 36:4, pages 331-340.
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Articles from other publishers (13)

Nevena Todorović Vukotić, Jelena Đorđević, Snežana Pejić, Neda Đorđević & Snežana B. Pajović. (2021) Antidepressants- and antipsychotics-induced hepatotoxicity. Archives of Toxicology 95:3, pages 767-789.
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Başak Togar, Hasan Turkez, Abdulgani Tatar, Ismet Kırkpınar, Ahmet Hacımuftuoglu, Fatime Geyikoglu, M Sait Keles & Ebubekir Dirican. (2011) The genotoxic potentials of some atypical antipsychotic drugs on human lymphocytes. Toxicology and Industrial Health 28:4, pages 327-333.
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Hasan T?rkez & Ba?ak To?ar. (2010) The genotoxic and oxidative damage potential of olanzapine in vitro. Toxicology and Industrial Health 26:9, pages 583-588.
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Ramesh B. Bambal & Stephen E. Clarke. 2009. Evaluation of Drug Candidates for Preclinical Development. Evaluation of Drug Candidates for Preclinical Development 55 107 .
Esther M. van der Zwaal, Mieneke C.M. Luijendijk, Roger A.H. Adan & Susanne E. la Fleur. (2008) Olanzapine-induced weight gain: Chronic infusion using osmotic minipumps does not result in stable plasma levels due to degradation of olanzapine in solution. European Journal of Pharmacology 585:1, pages 130-136.
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Chin B. Eap, Stefan Bender, Eveline Jaquenoud Sirot, Gianni Cucchia, Michèle Jonzier-Perey, Pierre Baumann, Delphine Allorge & Franck Broly. (2004) Nonresponse to Clozapine and Ultrarapid CYP1A2 Activity. Journal of Clinical Psychopharmacology 24:2, pages 214-219.
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Juan Antonio Carrillo, Angustias G. Herr?iz, Sara Isabel Ramos, Guillermo Gervasini, Sonia Vizca?no & Julio Ben?tez. (2003) Role of the Smoking-Induced Cytochrome P450 (CYP)1A2 and Polymorphic CYP2D6 in Steady-State Concentration of Olanzapine. Journal of Clinical Psychopharmacology 23:2, pages 119-127.
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Megan A Gibbs & Natilie A Hosea. (2003) Factors Affecting the Clinical Development of Cytochrome P450 3A Substrates. Clinical Pharmacokinetics 42:11, pages 969-984.
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Kristian Linnet & Ole V. Olesen. (2002) Free and Glucuronidated Olanzapine Serum Concentrations in Psychiatric Patients: Influence of Carbamazepine Comedication. Therapeutic Drug Monitoring 24:4, pages 512-517.
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Kristian Linnet. (2002) Glucuronidation of olanzapine by cDNA‐expressed human UDP‐glucuronosyltransferases and human liver microsomes. Human Psychopharmacology: Clinical and Experimental 17:5, pages 233-238.
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Yoshie Hirano, Mayumi Uehara, Ken-ichi Saeki, Taka-aki Kato, Kazuhiko Takahashi & Takaharu Mizutani. (2002) The Influence of Quinolines on Coumarin 7-Hydroxylation in Bovine Liver Microsomes and Human CYP2A6.. Journal of Health Science 48:2, pages 118-125.
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Heidi L. Liston, John S. Markowitz & C. Lindsay DeVane. (2001) Drug Glucuronidation in Clinical Psychopharmacology. Journal of Clinical Psychopharmacology 21:5, pages 500-515.
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Silvio Caccia. (2000) Biotransformation of Post-Clozapine Antipsychotics. Clinical Pharmacokinetics 38:5, pages 393-414.
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