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Research Article

KINETIC AND CHEMICAL MECHANISM OF EPOXIDE HYDROLASE*

Pages 71-86 | Published online: 02 Aug 1999

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A. M. Belliard, B. Baune, M. Fakhfakh, R. Hocquemiller & R. Farinotti. (2003) Determination of the human cytochrome P450s involved in the metabolism of 2n -propylquinoline. Xenobiotica 33:4, pages 341-355.
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RICHARD N. ARMSTRONG & CONSTANCE S. CASSIDY. (2000) NEW STRUCTURAL AND CHEMICAL INSIGHT INTO THE CATALYTIC MECHANISM OF EPOXIDE HYDROLASES*. Drug Metabolism Reviews 32:3-4, pages 327-338.
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Eila Serrano-Hervás, Marc Garcia-Borràs & Sílvia Osuna. (2017) Exploring the origins of selectivity in soluble epoxide hydrolase from Bacillus megaterium . Organic & Biomolecular Chemistry 15:41, pages 8827-8835.
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X.-Q. Li, M. A. Hayes, G. Gronberg, K. Berggren, N. Castagnoli & L. Weidolf. (2016) Discovery of a Novel Microsomal Epoxide Hydrolase-Catalyzed Hydration of a Spiro Oxetane. Drug Metabolism and Disposition 44:8, pages 1341-1348.
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Quan Luo, Yuan Yao, Wei-Wei Han, Yi-Han Zhou & Ze-Sheng Li. (2009) Homology modeling of a novel epoxide hydrolase (EH) from Aspergillus niger SQ-6: structure-activity relationship in expoxides inhibiting EH activity. Journal of Molecular Modeling 15:9, pages 1125-1132.
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Eun Yeol Lee. (2008) Epoxide hydrolase-mediated enantioconvergent bioconversions to prepare chiral epoxides and alcohols. Biotechnology Letters 30:9, pages 1509-1514.
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Bernard Testa & Stefanie D. Krämer. (2007) The Biochemistry of Drug Metabolism – An Introduction. Chemistry & Biodiversity 4:9, pages 2031-2122.
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David F.V. Lewis, Brian G. Lake & Michael G. Bird. (2005) Molecular modelling of human microsomal epoxide hydrolase (EH) by homology with a fungal (Aspergillus niger) EH crystal structure of 1.8 Å resolution: structure–activity relationships in epoxides inhibiting EH activity. Toxicology in Vitro 19:4, pages 517-522.
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Birgit Schiøtt. (2004) Possible involvement of collective domain movement in the catalytic reaction of soluble epoxide hydrolase. International Journal of Quantum Chemistry 99:2, pages 61-69.
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Tonya F Severson, Marvin H Goodrow, Christophe Morisseau, Deanna L Dowdy & Bruce D Hammock. (2002) Urea and amide-based inhibitors of the juvenile hormone epoxide hydrolase of the tobacco hornworm (Manduca sexta: Sphingidae). Insect Biochemistry and Molecular Biology 32:12, pages 1741-1756.
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Gregory C. Adam, Erik J. Sorensen & Benjamin F. Cravatt. (2002) Proteomic profiling of mechanistically distinct enzyme classes using a common chemotype. Nature Biotechnology 20:8, pages 805-809.
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Christophe Morisseau & Bruce D. Hammock. 2002. Wiley Encyclopedia of Molecular Medicine. Wiley Encyclopedia of Molecular Medicine.
Christophe Morisseau, John W. Newman, Deanna L. Dowdy, Marvin H. Goodrow & Bruce D. Hammock. (2001) Inhibition of Microsomal Epoxide Hydrolases by Ureas, Amides, and Amines. Chemical Research in Toxicology 14:4, pages 409-415.
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Alain Archelas & Roland Furstoss. (2001) Synthetic applications of epoxide hydrolases. Current Opinion in Chemical Biology 5:2, pages 112-119.
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Thomas H. Faller, György A. Csanády, Paul E. Kreuzer, Cordula M. Baur & Johannes G. Filser. (2001) Kinetics of Propylene Oxide Metabolism in Microsomes and Cytosol of Different Organs from Mouse, Rat, and Humans. Toxicology and Applied Pharmacology 172:1, pages 62-74.
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Mira A.M. Wenker, Sanja Kez̆ić, Aart C. Monster & Frederik A. de Wolff. (2000) Metabolism of Styrene-7,8-oxide in Human Liver in Vitro: Interindividual Variation and Stereochemistry. Toxicology and Applied Pharmacology 169:1, pages 52-58.
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Russell J. Linderman, R.Michael Roe, Shannon V. Harris & Deborah M. Thompson. (2000) Inhibition of insect juvenile hormone epoxide hydrolase: asymmetric synthesis and assay of glycidol-ester and epoxy-ester inhibitors of Trichoplusia ni epoxide hydrolase. Insect Biochemistry and Molecular Biology 30:8-9, pages 767-774.
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Jinyu Zou, B Martin Hallberg, Terese Bergfors, Franz Oesch, Michael Arand, Sherry L Mowbray & T Alwyn Jones. (2000) Structure of Aspergillus niger epoxide hydrolase at 1.8 ? resolution: implications for the structure and function of the mammalian microsomal class of epoxide hydrolases. Structure 8:2, pages 111-122.
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Christophe Morisseau, Marvin H. Goodrow, Deanna Dowdy, Jiang Zheng, Jessica F. Greene, James R. Sanborn & Bruce D. Hammock. (1999) Potent urea and carbamate inhibitors of soluble epoxide hydrolases. Proceedings of the National Academy of Sciences 96:16, pages 8849-8854.
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