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Drug Metabolism Reviews Volume 31, 1999 - Issue 1
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Research Article

KINETICS OF HYDROLYSIS AND REACTION OF AFLATOXIN B1EXO-8,9-EPOXIDE AND RELEVANCE TO TOXICITY AND DETOXICATION*,†

F. PETER GUENGERICH Department of Biochemistry and Center in Molecular Toxicology, Vanderbilt University School of Medicine, Nashville, Tennessee, 37232-0146, U.S.A.; Department of Biochemistry and Center in Molecular Toxicology, Vanderbilt University School of Medicine, Medical Research Building I, Room 638, 23rd Avenue South and Pierce, Nashville, TN, 37232-0146, U.S.A.
&
WILLIAM W. JOHNSON Schering-Plough Corporation, P.O. Box 32, 144 Route 94, Lafayette, NJ, 07848, U.S.A.
Pages 141-158 | Published online: 02 Aug 1999

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Daiane Cristina Sass, Alessandra Vincenzi Jager, Fernando Gustavo Tonin, Roice Eliana Rosim, Mauricio Gomes Constantino & Carlos Augusto Fernandes Oliveira. (2015) Synthesis and purification of the aflatoxin B1-lysine adduct. Toxin Reviews 34:1, pages 53-59.
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M.C. Lozano & G.J. Diaz. (2006) Microsomal and cytosolic biotransformation of aflatoxin B1 in four poultry species. British Poultry Science 47:6, pages 734-741.
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F. PETER GUENGERICH. (1999) THE VANDERBILT UNIVERSITY CENTER IN MOLECULAR TOXICOLOGY: THE FIRST 30 YEARS. Drug Metabolism Reviews 31:1, pages 1-11.
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Articles from other publishers (27)

Xinyu Sun, Jiadi Sun, Yongli Ye, Jian Ji, Lina Sheng, Diaodiao Yang & Xiulan Sun. (2023) Metabolic pathway-based self-assembled Au@MXene liver microsome electrochemical biosensor for rapid screening of aflatoxin B1. Bioelectrochemistry 151, pages 108378.
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Yasutaka Miyachi, Taiyi Kuo, Jinsook Son & Domenico Accili. (2021) Aldo-ketoreductase 1c19 ablation does not affect insulin secretion in murine islets. PLOS ONE 16:11, pages e0260526.
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X. Y. Xia, W. Sun, W. He, Y. Feng, L. Zhan & Y. Luo. (2020) A Modified Synthesis of Oxetan-3-ol. Russian Journal of Organic Chemistry 56:5, pages 877-883.
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Xiaolu Wang, Xing Qin, Zhenzhen Hao, Huiying Luo, Bin Yao & Xiaoyun Su. (2019) Degradation of Four Major Mycotoxins by Eight Manganese Peroxidases in Presence of a Dicarboxylic Acid. Toxins 11:10, pages 566.
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T.M. Penning. 2018. Comprehensive Toxicology. Comprehensive Toxicology 164 189 .
Gabriele Sabbioni & Robert J. Turesky. (2016) Biomonitoring Human Albumin Adducts: The Past, the Present, and the Future. Chemical Research in Toxicology 30:1, pages 332-366.
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Matthew Pratt-Hyatt, Andrew J. Lickteig & Curtis D. Klaassen. (2013) Tissue Distribution, Ontogeny, and Chemical Induction of Aldo-Keto Reductases in Mice. Drug Metabolism and Disposition 41:8, pages 1480-1487.
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Bernard Testa. (2013) Organic Stereochemistry. Part 8. Helvetica Chimica Acta 96:8, pages 1409-1451.
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Mohammad Navid Soltani Rad & Somayeh Behrouz. (2012) The base-free chemoselective ring opening of epoxides with carboxylic acids using [bmim]Br: a rapid entry into 1,2-diol mono-esters synthesis. Molecular Diversity 17:1, pages 9-18.
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Slobodan Rendic & F. Peter Guengerich. (2012) Contributions of Human Enzymes in Carcinogen Metabolism. Chemical Research in Toxicology 25:7, pages 1316-1383.
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R.I. Sanchez & F.C. Kauffman. 2010. Comprehensive Toxicology. Comprehensive Toxicology 109 128 .
T.M. Penning. 2010. Comprehensive Toxicology. Comprehensive Toxicology 149 167 .
Donald G. Barceloux. 2008. Medical Toxicology of Natural Substances. Medical Toxicology of Natural Substances 317 371 .
Yu. N. Bespal’ko, E. N. Shved & N. M. Oleinik. (2008) Peculiarities of catalytic behavior of bases in the reaction of aliphatic carboxylic acids with epoxide. Theoretical and Experimental Chemistry 44:5, pages 300-306.
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F. Peter Guengerich. (2007) Cytochrome P450 and Chemical Toxicology. Chemical Research in Toxicology 21:1, pages 70-83.
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Bernard Testa & Stefanie D. Krämer. (2007) The Biochemistry of Drug Metabolism – An Introduction. Chemistry & Biodiversity 4:9, pages 2031-2122.
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Trevor M. Penning & Jason E. Drury. (2007) Human aldo–keto reductases: Function, gene regulation, and single nucleotide polymorphisms. Archives of Biochemistry and Biophysics 464:2, pages 241-250.
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Yi JinTrevor M. Penning. (2007) Aldo-Keto Reductases and Bioactivation/Detoxication. Annual Review of Pharmacology and Toxicology 47:1, pages 263-292.
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John S. Walsh. 2006. Optimizing the “Drug-Like” Properties of Leads in Drug Discovery. Optimizing the “Drug-Like” Properties of Leads in Drug Discovery 49 80 .
F. Peter Guengerich. (2016) Life and Times in Biochemical Toxicology. International Journal of Toxicology 24:1, pages 5-21.
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F. Peter Guengerich. (2005) Principles of covalent binding of reactive metabolites and examples of activation of bis-electrophiles by conjugation. Archives of Biochemistry and Biophysics 433:2, pages 369-378.
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F Peter Guengerich. (2003) Cytochrome P450 oxidations in the generation of reactive electrophiles: epoxidation and related reactions. Archives of Biochemistry and Biophysics 409:1, pages 59-71.
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N. P. E. Vermeulen. 2003. Stereochemical Aspects of Drug Action and Disposition. Stereochemical Aspects of Drug Action and Disposition 229 248 .
F.Peter Guengerich. (2001) Forging the links between metabolism and carcinogenesis. Mutation Research/Reviews in Mutation Research 488:3, pages 195-209.
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Adrian J Fretland & Curtis J Omiecinski. (2000) Epoxide hydrolases: biochemistry and molecular biology. Chemico-Biological Interactions 129:1-2, pages 41-59.
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Hyang-Sook Chun, Paul A Kuzmicky, Laura Rucoba, Norman Y Kado & Robert H Rice. (2000) Cytotoxicity and keratinocyte microsome-mediated mutagenic activation of carcinogens in cultured epidermal cells. Toxicology Letters 115:2, pages 165-172.
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F. Peter Guengerich. (2000) Metabolism of chemical carcinogens. Carcinogenesis 21:3, pages 345-351.
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