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Journal of Asthma Volume 40, 2003 - Issue 8
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Original Article

Expression of Transforming Growth Factor β1 in Bronchial Biopsies in Asthma and COPD

Nurdan Kokturk Department of Pulmonary Medicine, Gazi University School of Medicine, Ankara, 06510, Turkey; , Kizilirmak Sok. 16/10, Kocatepe, Ankara, 06640, Turkey
, M.D.,
Turkan Tatlicioglu Department of Pulmonary Medicine, Gazi University School of Medicine, Ankara, 06510, Turkey
, M.D.,
Leyla Memis Department of Pathology, Gazi University School of Medicine, Ankara, 06510, Turkey
, M.D.,
Nalan Akyurek Department of Pathology, Gazi University School of Medicine, Ankara, 06510, Turkey
, M.D. &
Gulen Akyol Department of Pathology, Gazi University School of Medicine, Ankara, 06510, Turkey
, M.D.
Pages 887-893 | Published online: 13 Jan 2005

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Sukhwinder Singh Sohal, Chris Ward, Wan Danial, Richard Wood-Baker & Eugene Haydn Walters. (2013) Recent advances in understanding inflammation and remodeling in the airways in chronic obstructive pulmonary disease. Expert Review of Respiratory Medicine 7:3, pages 275-288.
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Ammaranond Palanee & Thantiworasit Pattarawat. (2012) STUDY ON THE EXPRESSION OF CO-STIMULATORY MARKER CD134 ON CD4+ T CELLS IN HIV-1–INFECTED INDIVIDUALS. Journal of Immunoassay and Immunochemistry 33:2, pages 195-202.
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Hye-Ryun Kang, Jae-Young Lee & Chun Geun Lee. (2008) TGF-β1 as a therapeutic target for pulmonary fibrosis and COPD. Expert Review of Clinical Pharmacology 1:4, pages 547-558.
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Articles from other publishers (26)

Maral Ranjbar, Christiane E. Whetstone, Hafsa Omer, Lucy Power, Ruth P. Cusack & Gail M. Gauvreau. (2022) The Genetic Factors of the Airway Epithelium Associated with the Pathology of Asthma. Genes 13:10, pages 1870.
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Xiaohua Gui, Zhongli Yang & Ming D. Li. (2021) Effect of Cigarette Smoke on Gut Microbiota: State of Knowledge. Frontiers in Physiology 12.
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Antonino Di Stefano, Claudia Sangiorgi, Isabella Gnemmi, Paolo Casolari, Paola Brun, Fabio L.M. Ricciardolo, Marco Contoli, Alberto Papi, Pio Maniscalco, Paolo Ruggeri, Giuseppe Girbino, Francesco Cappello, Stelios Pavlides, Yike Guo, Kian Fan Chung, Peter J. Barnes, Ian M. Adcock, Bruno Balbi & Gaetano Caramori. (2018) TGF-β Signaling Pathways in Different Compartments of the Lower Airways of Patients With Stable COPD. Chest 153:4, pages 851-862.
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Ajay P. Nayak, Deepak A. Deshpande & Raymond B. Penn. (2018) New targets for resolution of airway remodeling in obstructive lung diseases. F1000Research 7, pages 680.
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Tarcísio Vila Verde Santana de Almeida, Jamille Souza Fernandes, Diego Mota Lopes, Lorena Santana Andrade, Sérgio Costa Oliveira, Edgar M. Carvalho, Maria Ilma Araujo, Álvaro A. Cruz & Luciana Santos Cardoso. (2017) Schistosoma mansoni antigens alter activation markers and cytokine profile in lymphocytes of patients with asthma. Acta Tropica 166, pages 268-279.
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Fei Xu, Xiuhua Kang, Liang Chen, Chuanhui Chen, Gen Hu, Wei Bai & Wei Zhang. (2016) Generation of IL10 and TGFB1 coexpressed mice displaying resistance to ovalbumin-induced asthma. Transgenic Research 25:6, pages 829-837.
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Jian-Chu Zhang, Gang Chen, Long Chen, Zhao-Ji Meng, Xian-Zhi Xiong, Hong-Ju Liu, Yang Jin, Xiao-Nan Tao, Jiang-Hua Wu & Sheng-Wen Sun. (2016) TGF-β/BAMBI pathway dysfunction contributes to peripheral Th17/Treg imbalance in chronic obstructive pulmonary disease. Scientific Reports 6:1.
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Peter J. Barnes. (2016) Kinases as Novel Therapeutic Targets in Asthma and Chronic Obstructive Pulmonary Disease. Pharmacological Reviews 68:3, pages 788-815.
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Irene MJ Eurlings, Mieke A Dentener, Jack PM Cleutjens, Carine J Peutz, Gernot GU Rohde, Emiel FM Wouters & Niki L Reynaert. (2014) Similar matrix alterations in alveolar and small airway walls of COPD patients. BMC Pulmonary Medicine 14:1.
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Irene M. J. Eurlings, Niki L. Reynaert, Twan van den Beucken, Harry R. Gosker, C. C. de Theije, Fien M. Verhamme, Ken R. Bracke, Emiel F. M. Wouters & Mieke A. Dentener. (2014) Cigarette Smoke Extract Induces a Phenotypic Shift in Epithelial Cells; Involvement of HIF1α in Mesenchymal Transition. PLoS ONE 9:10, pages e107757.
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Talha Ijaz, Konrad Pazdrak, Mridul Kalita, Rolf Konig, Sanjeev Choudhary, Bing Tian, Istvan Boldogh & Allan R. Brasier. (2014) Systems biology approaches to understanding Epithelial Mesenchymal Transition (EMT) in mucosal remodeling and signaling in asthma. World Allergy Organization Journal 7, pages 13.
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Anna-Karin Larsson-Callerfelt, Oskar Hallgren, Annika Andersson-Sjöland, Lena Thiman, Johan Björklund, Josefine Kron, Kristian Nihlberg, Leif Bjermer, Claes-Göran Löfdahl & Gunilla Westergren-Thorsson. (2013) Defective alterations in the collagen network to prostacyclin in COPD lung fibroblasts. Respiratory Research 14:1, pages 21.
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Amir Soltani, Sukhwinder Singh Sohal, David Reid, Steve Weston, Richard Wood-Baker & E. Haydn Walters. (2012) Vessel-Associated Transforming Growth Factor-Beta1 (TGF-β1) Is Increased in the Bronchial Reticular Basement Membrane in COPD and Normal Smokers. PLoS ONE 7:6, pages e39736.
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Yi Gong, Liang Fan, Huanying Wan, Yuheng Shi, Guochao Shi, Yun Feng, Jialing Liu, Lei Ni, Chunming Pan & Ruifeng Zhang. (2011) Lack of Association Between the TGF-β1 Gene and Development of COPD in Asians: A Case–Control Study and Meta-analysis. Lung 189:3, pages 213-223.
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Judith C.W. Mak, Moira M.W. Chan-Yeung, Siu P. Ho, Kin S. Chan, Kahlin Choo, Kwok S. Yee, Chi H. Chau, Amy H.K. Cheung & Mary S.M. Ip. (2009) Elevated plasma TGF-β1 levels in patients with chronic obstructive pulmonary disease. Respiratory Medicine 103:7, pages 1083-1089.
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Katrin Presser, Dorothee Schwinge, Michael Wegmann, Samuel Huber, Steffen Schmitt, Alexander Quaas, Joachim H. Maxeiner, Susetta Finotto, Ansgar W. Lohse, Manfred Blessing & Christoph Schramm. (2008) Coexpression of TGF-β1 and IL-10 Enables Regulatory T Cells to Completely Suppress Airway Hyperreactivity. The Journal of Immunology 181:11, pages 7751-7758.
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Jerzy Liebhart, Malgorzata Polak, Andrzej Dabrowski, Rafal Dobek, Ewa Liebhart, Anna Dor-Wojnarowska, Wojciech Barg, Aleksandra Kulczak, Wojciech Medrala, Urszula Gladysz & Andrzej Lange. (2008) The G/G genotype of transforming growth factor beta 1 (TGF-β1) single nucleotide (+915G/C) polymorphism coincident with other host and environmental factors is associated with irreversible bronchoconstriction in asthmatics. International Journal of Immunogenetics 35:6, pages 417-422.
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Masashi Yamasaki, Hye–Ryun Kang, Robert J. Homer, Svetlana P. Chapoval, Soo Jung Cho, Byung Jae Lee, Jack A. Elias & Chun Geun Lee. (2008) P21 Regulates TGF-β 1 –Induced Pulmonary Responses via a TNF-α–Signaling Pathway . American Journal of Respiratory Cell and Molecular Biology 38:3, pages 346-353.
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Muhammad T. Salam, W. James Gauderman, Rob McConnell, Pi-Chu Lin & Frank D. Gilliland. (2007) Transforming Growth Factor-β1 C-509T Polymorphism, Oxidant Stress, and Early-Onset Childhood Asthma. American Journal of Respiratory and Critical Care Medicine 176:12, pages 1192-1199.
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Ynuk Bossé & Marek Rola-Pleszczynski. (2007) Controversy surrounding the increased expression of TGFβ1 in asthma. Respiratory Research 8:1.
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Kelly L. McCann & Farhad Imani. (2007) Transforming Growth Factor β Enhances Respiratory Syncytial Virus Replication and Tumor Necrosis Factor Alpha Induction in Human Epithelial Cells. Journal of Virology 81:6, pages 2880-2886.
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Cleo C van Diemen, Dirkje S Postma, Judith M Vonk, Marcel Bruinenberg, Ilja M Nolte & H Marike Boezen. (2006) Decorin and TGF-β 1 polymorphisms and development of COPD in a general population. Respiratory Research 7:1.
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Nurdan Kokturk, Pinar Firat, Hadi Akay, Cem Kadilar, Can Ozturk, Faruk Zorlu, Yucel Gungen & Salih Emri. (2005) Prognostic significance of Bax and Fas Ligand in erionite and asbestos induced Turkish malignant pleural mesothelioma. Lung Cancer 50:2, pages 189-198.
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Jenny H. Kim, Deepika Jain, Omar Tliba, Bei Yang, William F. JesterJr.Jr., Reynold A. PanettieriJr.Jr., Yassine Amrani & Ellen Puré. (2005) TGF-β potentiates airway smooth muscle responsiveness to bradykinin. American Journal of Physiology-Lung Cellular and Molecular Physiology 289:4, pages L511-L520.
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Judith C.W. Mak, Siu P. Ho, Raymond Y.H. Leung, Pak L. Ho, Clara Ooi, George L. Tipoe, Christina Yan, Mary S.M. Ip, Wah K. Lam & Kenneth W.T. Tsang. (2005) Elevated levels of transforming growth factor-β1 in serum of patients with stable bronchiectasis. Respiratory Medicine 99:10, pages 1223-1228.
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Peter J. Barnes. (2004) Mediators of Chronic Obstructive Pulmonary Disease. Pharmacological Reviews 56:4, pages 515-548.
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