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Review Article

Once‐Daily Inhaled Budesonide for the Treatment of Asthma: Clinical Evidence and Pharmacokinetic Explanation

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Pages 771-790 | Published online: 02 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Neil C Thomson & Mark Spears. (2013) Inhaled corticosteroids for asthma: on-demand or continuous use. Expert Review of Respiratory Medicine 7:6, pages 687-699.
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Eric D Bateman. (2013) Efficacy and safety of high-dose ciclesonide for the treatment of severe asthma. Expert Review of Respiratory Medicine 7:4, pages 339-348.
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Gunnar Persson, Jaro Ankerst, Michael Gillen, Thomas Bengtsson & Lars Thorsson. (2008) Relative systemic availability of budesonide in patients with asthma after inhalation from two dry powder inhalers. Current Medical Research and Opinion 24:5, pages 1511-1517.
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Edward M. Kerwin, David S. Pearlman, Teresita de Guia, Lars-Göran Carlsson, Michael Gillen, Tom Uryniak & Steven G. Simonson. (2008) Evaluation of efficacy and safety of budesonide delivered via two dry powder inhalers. Current Medical Research and Opinion 24:5, pages 1497-1510.
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A. Escribano, A. Tutuncu, I. Löhr, M. Carlholm & T. Polanowski. (2006) Clinical comparability between the CFC and HFA budesonide pressurised metered-dose inhalers in paediatric patients with asthma: a randomised controlled trial. Current Medical Research and Opinion 22:6, pages 1085-1092.
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Articles from other publishers (14)

Tao-Tao Fu, Yun Zhao, Fei-Fei Yang, Han Wen, Chun-Yu Liu & Yong-Hong Liao. (2018) Ciclesonide and budesonide suspensions for nebulization delivery: An in vivo inhalation biopharmaceutics investigation. International Journal of Pharmaceutics 549:1-2, pages 21-30.
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Piotr Kuna, Magnus Aurivillius, Carin Jorup, Susanne Prothon, Ziad Taib & Staffan Edsbäcker. (2017) Efficacy and Tolerability of an Inhaled Selective Glucocorticoid Receptor Modulator – AZD5423 – in Chronic Obstructive Pulmonary Disease Patients: Phase II Study Results. Basic & Clinical Pharmacology & Toxicology 121:4, pages 279-289.
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Jian-guo Jin, Hai-jian Shen, Yuan-lu Shan, Lei Chen, Xi-yue Zhao, Liang-rong Wang & Li-na Lin. (2016) Effect of two administration routes of Shenmai Injection (参麦注射液) on pulmonary gas exchange function after tourniquet-induced ischemia-reperfusion. Chinese Journal of Integrative Medicine 23:1, pages 18-24.
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Marika Melamies, Outi Vainio, Thomas Spillmann, Jouni Junnila & Minna M. Rajamäki. (2012) Endocrine effects of inhaled budesonide compared with inhaled fluticasone propionate and oral prednisolone in healthy Beagle dogs. The Veterinary Journal 194:3, pages 349-353.
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Chee-Hoon Chang, Tekla M. Lee-Fowler, Amy E. DeClue, Leah A. Cohn, Katherine L. Robinson & Carol R. Reinero. (2011) The impact of oral versus inhaled glucocorticoids on allergen specific IgE testing in experimentally asthmatic cats. Veterinary Immunology and Immunopathology 144:3-4, pages 437-441.
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Karen I. Maassen van den Brink, Martin Boorsma, A. Jeske Staal-van den Brekel, Staffam Edsbäcker, Emiel F. Wouters & Lars Thorsson. (2008) Evidence of the in vivo esterification of budesonide in human airways. British Journal of Clinical Pharmacology 66:1, pages 27-35.
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Seth J. Kanowitz, Pete S. Batra & Martin J. Citardi. (2008) Topical budesonide via mucosal atomization device in refractory postoperative chronic rhinosinusitis. Otolaryngology–Head and Neck Surgery 139:1, pages 131-136.
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Staffan Edsbäcker, Per Wollmer, Olof Selroos, Lars Borgström, Bo Olsson & Jarl Ingelf. (2008) Do airway clearance mechanisms influence the local and systemic effects of inhaled corticosteroids?. Pulmonary Pharmacology & Therapeutics 21:2, pages 247-258.
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Kristina Lexmüller, Helena Gullstrand, Bengt-Olof Axelsson, Petter Sjölin, Solange H. Korn, David S. Silberstein & Anna Miller-Larsson. (2007) Differences in Endogenous Esterification and Retention in the Rat Trachea between Budesonide and Ciclesonide Active Metabolite. Drug Metabolism and Disposition 35:10, pages 1788-1796.
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Andrea von Berg, Renate Engelstätter, Predrag Minic, Miodrag Sréckovic, Maria Luz Garcia Garcia, Tadeusz Latoś, Jan H. Vermeulen, Stefan Leichtl, Stefan Hellbardt & Thomas D. Bethke. (2007) Comparison of the efficacy and safety of ciclesonide 160�?g once daily vs. budesonide 400�?g once daily in children with asthma. Pediatric Allergy and Immunology 18:5, pages 391-400.
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J. Mallol & V. Aguirre. (2007) Once versus twice daily budesonide metered-dose inhaler in children with mild to moderate asthma: effect on symptoms and bronchial responsiveness. Allergologia et Immunopathologia 35:1, pages 25-31.
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Staffan Edsbacker & Carl-Johan Johansson. (2006) Airway Selectivity: An Update of Pharmacokinetic Factors Affecting Local and Systemic Disposition of Inhaled Steroids. Basic <html_ent glyph="@amp;" ascii="&"/> Clinical Pharmacology <html_ent glyph="@amp;" ascii="&"/> Toxicology 98:6, pages 523-536.
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. (2006) Current World Literature. Current Opinion in Allergy & Clinical Immunology 6:3, pages 241-248.
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Trevor T. Hansel, Olivier Benezet, Henri Kafé, Hans-Hermann Ponitz, David Cheung, Renate Engelstätter & Peter J. Barnes. (2006) A multinational, 12-week, randomized study comparing the efficacy and tolerability of ciclesonide and budesonide in patients with asthma. Clinical Therapeutics 28:6, pages 906-920.
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