549
Views
41
CrossRef citations to date
0
Altmetric
Original

OXIDATIVE STRESS-MEDIATED RENAL DYSFUNCTION BY CYCLOSPORINE A IN RATS: ATTENUATION BY TRIMETAZIDINE

, M.Pharm. & , M.Pharm., Ph.D.
Pages 259-274 | Published online: 07 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Tan Y. Chia, Munavvar A. Sattar, Mohammed H. Abdulla, Hassaan A. Rathore, Fiaz ud Din Ahmad, Gurjeet Kaur, Nor A. Abdullah & Edward J. Johns. (2013) The effects of tempol on renal function and hemodynamics in cyclosporine-induced renal insufficiency rats. Renal Failure 35:7, pages 978-988.
Read now
Felipe Machado Silva, Luiz Antonio Miorin & Yvoty Alves dos Santos Sens. (2008) The Effect of Aldosterone Antagonist in Experimental Nephropathy Induced by Cyclosporine A. Renal Failure 30:4, pages 439-442.
Read now
Hakan Ay, Gunalp Uzun, Yalcin Onem, Secil Aydinoz, Senol Yildiz, Oguz Bilgi, Turgut Topal & Enes Murat Atasoyu. (2007) Effect of Hyperbaric Oxygen on Cyclosporine-Induced Nephrotoxicity and Oxidative Stress in Rats. Renal Failure 29:4, pages 495-501.
Read now
İlker Durak, Recep Çetin, Özden Çandır, Erdinç Devrim, Bülent Kılıçoğlu & Aslıhan Avcı. (2007) Black Grape and Garlic Extracts Protect Against Cyclosporine A Nephrotoxicity. Immunological Investigations 36:1, pages 105-114.
Read now
Muragundla Anjaneyulu, Naveen Tirkey & Kanwaljit Chopra. (2003) Attenuation of Cyclosporine-Induced Renal Dysfunction by Catechin: Possible Antioxidant Mechanism. Renal Failure 25:5, pages 691-707.
Read now

Articles from other publishers (35)

Sourav Khanra, Preethi Reddy, Anna Giménez-Palomo, Chun Hui J. Park, Bruna Panizzutti, Madeleine McCallum, Shyam Sundar Arumugham, Shreekantiah Umesh, Monojit Debnath, Basudeb Das, Ganesan Venkatasubramanian, Melanie Ashton, Alyna Turner, Olivia M. Dean, Ken Walder, Eduard Vieta, Lakshmi N. Yatham, Isabella Pacchiarotti, Y. C. Janardhan Reddy, Nishant Goyal, Muralidharan Kesavan, Lluc Colomer, Michael Berk & Jee Hyun Kim. (2023) Metabolic regulation to treat bipolar depression: mechanisms and targeting by trimetazidine. Molecular Psychiatry 28:8, pages 3231-3242.
Crossref
Rehab S. Abdelrahman, Ramy A. Abdelsalam & Marwa S. Zaghloul. (2022) Beneficial effect of trimetazidine on folic acid‐induced acute kidney injury in mice: Role of HIF‐1α/HO‐1. Journal of Biochemical and Molecular Toxicology 36:5.
Crossref
Jorge Andrade-Sierra, Mónica Lizbeth Morales-Guillén, Andrés García-Sánchez, Elodia Nataly Díaz-de la Cruz, José Ignacio Cerrillos-Gutiérrez, Enrique Rojas-Campos & Alejandra Guillermina Miranda-Díaz. (2022) The Effect of Enalapril, Losartan, or Not Antihypertensive on the Oxidative Status in Renal Transplant Recipients. Oxidative Medicine and Cellular Longevity 2022, pages 1-9.
Crossref
Hongju Wu & Vecihi Batuman. 2022. Diabetes and Kidney Disease. Diabetes and Kidney Disease 601 635 .
Kirti Gupta, Sneha Pandey, Newly Bagang, Kamalpreet Mehra & Gaaminepreet Singh. (2021) Trimetazidine an emerging paradigm in renal therapeutics: Preclinical and clinical insights. European Journal of Pharmacology 913, pages 174624.
Crossref
Alireza Raji-amirhasani, Mohammad Khaksari, Fatemeh Darvishzadeh Mahani & Zahra Hajializadeh. (2021) Activators of SIRT1 in the kidney and protective effects of SIRT1 during acute kidney injury (AKI) (effect of SIRT1 activators on acute kidney injury). Clinical and Experimental Nephrology 25:8, pages 807-821.
Crossref
Folake Lucy Oyetayo, Seun Funmilola Akomolafe & Gbemisola Beulah Balogun. (2021) Effects of Chrysophyllum albidum fruit pulp on haemodynamic parameters, pro-inflammatory markers, antioxidant parameters and critical biomolecules associated with hypertension–in vivo. Inflammopharmacology 29:3, pages 825-839.
Crossref
Felix Abayomi Dada, Sunday Idowu Oyeleye, Stephen Adeniyi Adefegha & Ganiyu Oboh. (2020) Extracts from Almond ( Terminalia catappa ) leaf and stem bark mitigate the activities of crucial enzymes and oxidative stress associated with hypertension in cyclosporine A‐stressed rats . Journal of Food Biochemistry 45:3.
Crossref
Yong Yang, Yong Wang, Zuowen He, Yunchang Liu, Chen Chen, Yan Wang, Dao Wen Wang & Hong Wang. (2020) Trimetazidine Inhibits Renal Tubular Epithelial Cells to Mesenchymal Transition in Diabetic Rats via Upregulation of Sirt1. Frontiers in Pharmacology 11.
Crossref
Odunayo Michael Agunloye, Ganiyu Oboh, Adedayo Oluwaseun Ademiluyi, Ayokunle Olubode Ademosun, Akintunde Afolabi Akindahunsi, Ademola Adetokunbo Oyagbemi, Temidayo Olutayo Omobowale, Temitayo Olabisi Ajibade & Adeolu Alex Adedapo. (2019) Cardio-protective and antioxidant properties of caffeic acid and chlorogenic acid: Mechanistic role of angiotensin converting enzyme, cholinesterase and arginase activities in cyclosporine induced hypertensive rats. Biomedicine & Pharmacotherapy 109, pages 450-458.
Crossref
Qinghua Wu, Xu Wang, Eugenie Nepovimova, Yun Wang, Hualin Yang & Kamil Kuca. (2018) Mechanism of cyclosporine A nephrotoxicity: Oxidative stress, autophagy, and signalings. Food and Chemical Toxicology 118, pages 889-907.
Crossref
Jin Ha Park, Ji Hae Jun, Jae-Kwang Shim, Eun Jung Shin, Eunah Shin & Young-Lan Kwak. (2018) Effects of Post Ischemia-Reperfusion Treatment with Trimetazidine on Renal Injury in Rats: Insights on Delayed Renal Fibrosis Progression. Oxidative Medicine and Cellular Longevity 2018, pages 1-10.
Crossref
Brian J. Nankivell, Chow H. P'Ng, Philip J. O'Connell & Jeremy R. Chapman. (2016) Calcineurin Inhibitor Nephrotoxicity Through the Lens of Longitudinal Histology. Transplantation 100:8, pages 1723-1731.
Crossref
Nagla A. El-SherbeenyGhalia M. Attia. (2016) The protective effect of trimetazidine against cisplatin-induced nephrotoxicity in rats. Canadian Journal of Physiology and Pharmacology 94:7, pages 745-751.
Crossref
Hayam Ateyya. (2015) Amelioration of cyclosporine induced nephrotoxicity by dipeptidyl peptidase inhibitor vildagliptin. International Immunopharmacology 28:1, pages 571-577.
Crossref
Yu Ah Hong, Ji Hee Lim, Min Young Kim, Eun Nim Kim, Eun Sil Koh, Seok Joon Shin, Bum Soon Choi, Cheol Whee Park, Yoon Sik Chang & Sungjin Chung. (2014) Delayed treatment with oleanolic acid attenuates tubulointerstitial fibrosis in chronic cyclosporine nephropathy through Nrf2/HO-1 signaling. Journal of Translational Medicine 12:1.
Crossref
Nagaraja Haleagrahara, Srikumar Chakravarthi, Anupama Bangra Kulur & Tan Mun Yee. (2014) Plant flavone apigenin protects against cyclosporine-induced histological and biochemical changes in the kidney in rats. Biomedicine & Preventive Nutrition 4:4, pages 589-593.
Crossref
Karvannan Kanchana & C. S. Parameswari. (2012) Protective effect of Phyllanthus niruri against cyclosporine A-induced nephrotoxicity in rats. Comparative Clinical Pathology 22:5, pages 885-893.
Crossref
Sun Woo Lim, Kyoung Chan Doh, Long Jin, Shang Guo Piao, Seong Beom Heo, Yu Fen Zheng, Soo Kyung Bae, Byung Ha Chung & Chul Woo Yang. (2013) Oral Administration of Ginseng Ameliorates Cyclosporine-Induced Pancreatic Injury in an Experimental Mouse Model. PLoS ONE 8:8, pages e72685.
Crossref
Sun Woo Lim, Bok Jin Hyoung, Shang Guo Piao, Kyoung Chan Doh, Byung Ha Chung & Chul Woo Yang. (2012) Chronic Cyclosporine Nephropathy Is Characterized by Excessive Autophagosome Formation and Decreased Autophagic Clearance. Transplantation 94:3, pages 218-225.
Crossref
Ranjana Singh, Parmeet K. Manchanda, Pravin Kesarwani, Aneesh Srivastava & Rama D. Mittal. (2009) Influence of genetic polymorphisms in GSTM1 , GSTM3 , GSTT1 and GSTP1 on allograft outcome in renal transplant recipients . Clinical Transplantation 23:4, pages 490-498.
Crossref
Ridha Ben Ali, Anis Klouz, Samir Boubaker, Mohamed Lakhal & Chalbi Belkahia. (2009) An animal model of testicular toxicity by cyclosporine: evaluation and protection. Fundamental & Clinical Pharmacology 23:2, pages 241-246.
Crossref
A. Ghorbanihaghjo, H. Argani, H. Foroughimoghaddam, J. Safa, N. Rashtchizadeh & M. Mesgari. (2008) Effect of Isoproterenol on Cyclosporine-Induced Nephrotoxicity in Rat. Transplantation Proceedings 40:10, pages 3737-3741.
Crossref
Hong Zhu, Li Zhang, Ashok R. Amin & Yunbo Li. (2008) Coordinated Upregulation of a Series of Endogenous Antioxidants and Phase 2 Enzymes as a Novel Strategy for Protecting Renal Tubular Cells from Oxidative and Electrophilic Stress. Experimental Biology and Medicine 233:6, pages 753-765.
Crossref
A. Onay-Besikci & S.A. Özkan. (2008) Trimetazidine Revisited: A Comprehensive Review of the Pharmacological Effects and Analytical Techniques for the Determination of Trimetazidine. Cardiovascular Therapeutics 26:2, pages 147-165.
Crossref
Hamidreza Montazeri Aliabadi, Sara Elhasi, Dion R. Brocks & Afsaneh Lavasanifar. (2008) Polymeric Micellar Delivery Reduces Kidney Distribution and Nephrotoxic Effects of Cyclosporine A After Multiple Dosing. Journal of Pharmaceutical Sciences 97:5, pages 1916-1926.
Crossref
R. A. Olivo, N. G. Nascimento, C. F. P. Teixeira & P. F. Silveira. (2008) Methotrexate and Cyclosporine Treatments Modify the Activities of Dipeptidyl Peptidase IV and Prolyl Oligopeptidase in Murine Macrophages. Clinical and Developmental Immunology 2008, pages 1-9.
Crossref
Hamidreza Montazeri Aliabadi, Tara J. Spencer, Parvin Mahdipoor, Afsaneh Lavasanifar & Dion R. Brocks. (2006) Insights into the effects of hyperlipoproteinemia on cyclosporine A biodistribution and relationship to renal function. The AAPS Journal 8:4, pages E672-E681.
Crossref
Sathish Kumar Natarajan, Jayasree Basivireddy, Anup Ramachandran, Simmy Thomas, Prabhu Ramamoorthy, Anna B. Pulimood, Molly Jacob & Kunissery A. Balasubramanian. (2006) Renal damage in experimentally-induced cirrhosis in rats: Role of oxygen free radicals. Hepatology 43:6, pages 1248-1256.
Crossref
Camila Eduardo Marinho, Renata do Amaral Olivo, Leonardo Zambotti-Villela, Tabatha Novikov Ribeiro-de-Andrade, Cristina Maria Fernandes & Paulo Flavio Silveira. (2006) Renal and macrophage aminopeptidase activities in cyclosporin-treated mice. International Immunopharmacology 6:3, pages 415-425.
Crossref
Enes Murat Atasoyu, Senol Yildiz, Maide Cimsit, Hakan Cermik, Tauland Qyrdedi, T. Rifki Evrenkaya, Samil Aktas, Gunalp Uzun, Oguz Bilgi & Mustafa Gultepe. (2006) Investigation of the Effect of Hyperbaric Oxygen on Experimental Cyclosporine Nephrotoxicity. Basic <html_ent glyph="@amp;" ascii="&"/> Clinical Pharmacology <html_ent glyph="@amp;" ascii="&"/> Toxicology 98:2, pages 150-154.
Crossref
Naveen Tirkey, Gaganjit Kaur, Garima Vij & Kanwaljit Chopra. (2005) Curcumin, a diferuloylmethane, attenuates cyclosporine-induced renal dysfunction and oxidative stress in rat kidneys. BMC Pharmacology 5:1.
Crossref
A.M. Mohamadin, H.A. El-Beshbishy & M.A. El-Mahdy. (2005) Green tea extract attenuates cyclosporine A-induced oxidative stress in rats. Pharmacological Research 51:1, pages 51-57.
Crossref
J. P. Faure, C. Jayle, D. Dutheil, M. Eugene, K. Zhang, J. M. Goujon, I. Petit-Paris, J. P. Tillement, G. Touchard, R. Robert, A. Wahl, F. Seguin, G. Mauco, A. Vandewalle & T. Hauet. (2004) Evidence for protective roles of polyethylene glycol plus high sodium solution and trimetazidine against consequences of renal medulla ischaemia during cold preservation and reperfusion in a pig kidney model. Nephrology Dialysis Transplantation 19:7, pages 1742-1751.
Crossref
Amanpreet Singh, Gaurav Kumar, Pattipati S. Naidu & Shrinivas K. Kulkarni. (2003) Protective effect of FK506 (Tacrolimus) in pentylenetetrazol-induced kindling in mice. Pharmacology Biochemistry and Behavior 75:4, pages 853-860.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.