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CLINICAL STUDY

Scrub Typhus: A Frequently Overlooked Cause of Acute Renal Failure

, M.D., , M.D., , M.D., , M.D. & , M.D.
Pages 397-410 | Published online: 26 Aug 2009

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Pamornsri Sriwongpan, Pornsuda Krittigamas, Hutsaya Tantipong, Jayanton Patumanond, Chamaiporn Tawichasri & Sirianong Namwongprom. (2014) Clinical risk-scoring algorithm to forecast scrub typhus severity. Risk Management and Healthcare Policy 7, pages 11-17.
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Sanjay Vikrant, Santosh Kumar Dheer, Anupam Parashar, Dalip Gupta, Surinder Thakur, Ashok Sharma, Satinder Singh Kaushal & Anil Kanga. (2013) Scrub typhus associated acute kidney injury—a study from a tertiary care hospital from western Himalayan state of India. Renal Failure 35:10, pages 1338-1343.
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Articles from other publishers (49)

Prit Kusirisin, Geraldo Bezerra da Silva Junior, Visith Sitprija & Nattachai Srisawat. (2022) Acute kidney injury in the tropics. Nephrology 28:1, pages 5-20.
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Makoto Kondo, Kohei Nishikawa, Shohei Iida, Takehisa Nakanishi, Koji Habe & Keiichi Yamanaka. (2022) Japanese Spotted Fever and Irreversible Renal Dysfunction during Immunosuppressive Therapy after a Living-Donor Kidney Transplant. Tropical Medicine and Infectious Disease 7:8, pages 175.
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Gaurav SinghDr.Dr., Nikhil BatraDr.Dr. & Shoib Ahamed MDr.Dr.. (2022) SCRUB TYPHUS AS DIFFERENTIAL DIAGNOSIS OF COVID-19 IN PRESENT SCENARIO : A CASE REPORT. INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH, pages 23-24.
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Arpana Iyengar & Vera Koch. 2022. Pediatric Nephrology. Pediatric Nephrology 673 706 .
Fauzia KhanDr.Dr. & Vandana SardanaDr.Dr.. (2021) CLINICO-DEMOGRAPHIC PROFILE OF SCRUB TYPHUS IN UTTARAKHAND. INDIAN JOURNAL OF APPLIED RESEARCH, pages 34-36.
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Chi Young YunJi Hye LimJu Hwan OhA Young ChoKwang Young LeeIn O Sun. (2021) Urinary Exosomal microRNA-21 as a Marker for Scrub Typhus-Associated Acute Kidney Injury. Genetic Testing and Molecular Biomarkers 25:2, pages 140-144.
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Arpana Iyengar & Vera Koch. 2020. Pediatric Nephrology. Pediatric Nephrology 1 34 .
Rebecca John & George M. Varghese. (2020) Scrub typhus: a reemerging infection. Current Opinion in Infectious Diseases 33:5, pages 365-371.
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Manri KAWAKAMI, Hiromi FUJITA, Shinichi FUJIOKA & Fusao IKEDA. (2019) A Recovered Case of Japanese Spotted Fever with Supportive Treatment Only有効な抗生剤の投与なく対症療法のみで治癒した日本紅斑熱の1 例. Kansenshogaku Zasshi 93:4, pages 525-528.
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Sandeep Kumar, Shrikiran Aroor, Pushpa Gurudas Kini, Suneel Mundkur & Manaswita Gadiparthi. (2019) Clinical and Laboratory Features of Rickettsial diseases in children in South India. Pediatric Oncall 16:1.
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Dinesh Kumar Narayanasamy, Thirunavukkarasu Arun Babu, Vijayasankar Vijayadevagaran, Devi Kittu & Shanthi Ananthakrishnan. (2018) Predictors of Severity in Pediatric Scrub Typhus. The Indian Journal of Pediatrics 85:8, pages 613-617.
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Areum Durey, Hea Yoon KwonYoung Kyoung ParkJiHyeon BaekSeung Baik HanJae-Seung KangJin-Soo Lee. (2018) A Case of Scrub Typhus complicated with a Splenic Infarction. Infection & Chemotherapy 50:1, pages 55.
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Emmanuel A. Burdmann & Vivekanand Jha. (2017) Acute kidney injury due to tropical infectious diseases and animal venoms: a tale of 2 continents. Kidney International 91:5, pages 1033-1046.
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In O. Sun, Sung Hye Shin, A. Young Cho, Hyun Ju Yoon, Mi Yok Chang & Kwang Young Lee. (2017) Clinical significance of NGAL and KIM-1 for acute kidney injury in patients with scrub typhus. PLOS ONE 12:4, pages e0175890.
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Narendra Rathi, Atul Kulkarni & Vijay Yewale. (2017) IAP guidelines on rickettsial diseases in children. Indian Pediatrics 54:3, pages 223-229.
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Kittipong SuwattanabunpotWilawan ThipmontreeYupin Supputtamonkol. (2016) Spontaneous Splenic Rupture Caused by Scrub Typhus. The American Journal of Tropical Medicine and Hygiene 95:6, pages 1284-1286.
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H.K. AggarwalD. JainP. Chhabra. (2016) Tropical Diseases Nephropathy - An Underemphasized Comorbidity. ARS Medica Tomitana 22:4, pages 239-248.
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Wiwit TantibhedhyangkulEkkarat WongsawatYupin SuputtamongkolWilawan ThipmontreeSaowaluk SilpasakornDuangdao Waywa. (2016) Scrub Typhus in Northeastern Thailand: Eschar Distribution, Abnormal Electrocardiographic Findings, and Predictors of Fatal Outcome. The American Journal of Tropical Medicine and Hygiene 95:4, pages 769-773.
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Thomas R. Shelite, Yuejin Liang, Hui Wang, Nicole L. Mendell, Brandon J. Trent, Jiaren Sun, Bin Gong, Guang Xu, Haitao Hu, Donald H. Bouyer & Lynn Soong. (2016) IL-33-Dependent Endothelial Activation Contributes to Apoptosis and Renal Injury in Orientia tsutsugamushi-Infected Mice. PLOS Neglected Tropical Diseases 10:3, pages e0004467.
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Gemma Vincent. 2016. Rickettsiales. Rickettsiales 329 372 .
Narendra Rathi. (2015) Rickettsial diseases in India – A long way ahead…. Pediatric Infectious Disease 7:3, pages 61-63.
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Suneeta Sahu, Sudhi Ranjan Misra, Prasant Padhan & Samir Sahu. (2015) Scrub typhus in a tertiary care hospital in the eastern part of Odisha. Apollo Medicine 12:1, pages 2-6.
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R Bithu, V Kanodia & RK Maheshwari. (2014) Possibility of scrub typhus in fever of unknown origin (FUO) cases: An experience from Rajasthan. Indian Journal of Medical Microbiology 32:4, pages 387-390.
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Thomas R. Shelite, Tais B. Saito, Nicole L. Mendell, Bin Gong, Guang Xu, Lynn Soong, Gustavo Valbuena, Donald H. Bouyer & David H. Walker. (2014) A Hematogenously Disseminated Orientia tsutsugamsushi-Infected Murine Model of Scrub Typhus. PLoS Neglected Tropical Diseases 8:7, pages e2966.
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In O Sun, Moon Chul Kim, Jae Woo Park, Min A. Yang, Cheon Beom Lee, Hyun Ju Yoon, Jeong Gwan Kim & Kwang Young Lee. (2014) Clinical characteristics of acute kidney injury in patients with scrub typhus – RIFLE criteria validation. Journal of Infection and Chemotherapy 20:2, pages 93-96.
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Vivek Kumar, Vinod Kumar, Ashok K. Yadav, Sreenivasa Iyengar, Ashish Bhalla, Navneet Sharma, Ritesh Aggarwal, Sanjay Jain & Vivekanand Jha. (2014) Scrub Typhus Is an Under-recognized Cause of Acute Febrile Illness with Acute Kidney Injury in India. PLoS Neglected Tropical Diseases 8:1, pages e2605.
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Jeong Min KimMiri HyunHyun Ah KimMi Kyung KimJin Young KimKi Young KwonSeong-Yeol Ryu. (2014) A Review of the Electrocardiography Changes and Clinical Manifestations of Scrub Typhus in a Single Center. Korean Journal of Medicine 86:3, pages 301.
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Dae-Yeon Kim, Hee-Soon Park, Dong-Jae Han, Hyo-Chul Kang, Ji-Hye Lee, Won-Jong Jang, Hyo-Wook Gil, Jong-Oh Yang, Eun-Young Lee & Sae-Yong Hong. (2013) A case of scrub typhus requiring maintenance hemodialysis. Kidney Research and Clinical Practice 32:4, pages 190-193.
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Ju Hyun LeeMi Jung LeeDong Ho ShinShin-Wook KangKyu Hun ChoiTae-Hyun Yoo. (2013) A case of Tsutsugamushi disease presenting with nephrotic syndrome. The Korean Journal of Internal Medicine 28:6, pages 728.
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Manish Kumar, Sriram Krishnamurthy, C.G. Delhikumar, Parameswaran Narayanan, Niranjan Biswal & Sadagopan Srinivasan. (2012) Scrub typhus in children at a tertiary hospital in southern India: Clinical profile and complications. Journal of Infection and Public Health 5:1, pages 82-88.
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Su Jin LeeYoung Hye ChoSang Yeoup LeeDong Wook JeongEun Jung ChoiYun Jin KimJeong Gyu LeeYu Hyun Lee. (2012) A Case of Scrub Typhus Complicated by Acute Calculous Cholecystitis. Korean Journal of Family Medicine 33:4, pages 243.
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Marina E. Eremeeva & Gregory A. Dasch. 2012. Principles and Practice of Pediatric Infectious Diseases. Principles and Practice of Pediatric Infectious Diseases 930 938.e4 .
Visith Sitprija, Kriang Tungsanga & Kearkiat Praditpornsilpa. 2012. Brenner and Rector's The Kidney. Brenner and Rector's The Kidney 2786 2802 .
Rashna Dass, Nayan Mani Deka, Sourabh Gohain Duwarah, Himesh Barman, Rejaul Hoque, Dwijendra Mili & Dibakar Barthakur. (2011) Characteristics of Pediatric Scrub Typhus during an Outbreak in the North Eastern Region of India: Peculiarities in Clinical Presentation, Laboratory Findings and Complications. The Indian Journal of Pediatrics 78:11, pages 1365-1370.
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Ashish Jacob Mathew & Jacob George. (2011) Acute kidney injury in the tropics. Annals of Saudi Medicine 31:5, pages 451-456.
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Dong-Min Kim, Geon Park, Hyong Sun Kim, Joo Young Lee, Ganesh Prasad Neupane, Stephen Graves & John Stenos. (2011) Comparison of Conventional, Nested, and Real-Time Quantitative PCR for Diagnosis of Scrub Typhus. Journal of Clinical Microbiology 49:2, pages 607-612.
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Hideo Yasunaga, Hiromasa Horiguchi, Kazuaki Kuwabara, Hideki Hashimoto & Shinya Matsuda. (2011) Delay in Tetracycline Treatment Increases the Risk of Complications in Tsutsugamushi Disease: Data from the Japanese Diagnosis Procedure Combination Database. Internal Medicine 50:1, pages 37-42.
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Ik-Sang Kim & David H. Walker. 2011. Tropical Infectious Diseases: Principles, Pathogens and Practice. Tropical Infectious Diseases: Principles, Pathogens and Practice 334 338 .
Dong-Min Kim, Seok Won Kim, Seong-Hyung Choi & Na Ra Yun. (2010) Clinical and laboratory findings associated with severe scrub typhus. BMC Infectious Diseases 10:1.
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Abdul Razak, Vishwanath Sathyanarayanan, Mukhyaprana Prabhu, Madhusudan Sangar & R Balasubramanian. (2010) Scrub typhus in Southern India: are we doing enough?. Tropical Doctor 40:3, pages 149-151.
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Anugrah ChrispalHarikishan BooruguKango Gopal GopinathJohn Antony Jude PrakashSara ChandyO C Abraham, Asha Mary AbrahamKurien Thomas. (2010) Scrub typhus: an unrecognized threat in South India – clinical profile and predictors of mortality. Tropical Doctor 40:3, pages 129-133.
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Narendra Rathi & Akanksha Rathi. (2010) Rickettsial infections: Indian perspective. Indian Pediatrics 47:2, pages 157-164.
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Ki Beom Bae. (2010) Massive small bowel bleeding caused by scrub typhus in Korea. World Journal of Gastrointestinal Surgery 2:1, pages 47.
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Kun-Ming Wu, Zhe-Wei Wu, Guo-Quan Peng, Jian Liang Wu & Shih-Yi Lee. (2009) Radiologic Pulmonary Findings, Clinical Manifestations and Serious Complications in Scrub Typhus: Experiences From A Teaching Hospital in Eastern Taiwan. International Journal of Gerontology 3:4, pages 223-232.
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Piengchan Sonthayanon, Wirongrong Chierakul, Vanaporn Wuthiekanun, Kriangsak Phimda, Sasithon Pukrittayakamee, Nicholas P. Day & Sharon J. Peacock. (2009) Association of High Orientia tsutsugamushi DNA Loads with Disease of Greater Severity in Adults with Scrub Typhus . Journal of Clinical Microbiology 47:2, pages 430-434.
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Dong-Min Kim, Dae Woong Kang, Jong O. Kim, Jong Hoon Chung, Hyun Lee Kim, Chi Young Park & Sung-Chul Lim. (2008) Acute Renal Failure Due to Acute Tubular Necrosis Caused by Direct Invasion of Orientia tsutsugamushi . Journal of Clinical Microbiology 46:4, pages 1548-1550.
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S. D. Blacksell, N. J. Bryant, D. H. Paris, J. A. Doust, Y. Sakoda & N. P. J. Day. (2007) Scrub Typhus Serologic Testing with the Indirect Immunofluorescence Method as a Diagnostic Gold Standard: A Lack of Consensus Leads to a Lot of Confusion. Clinical Infectious Diseases 44:3, pages 391-401.
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