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Research Article

Effect of Processing Methods and Heat Treatment on the Formation of Wax Matrix Tablets for Sustained Drug Release

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Pages 131-144 | Received 12 Nov 1999, Accepted 23 Feb 2000, Published online: 30 Apr 2001

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Kyu-Mok Hwang, Woojin Byun, Cheol-Hee Cho & Eun-Seok Park. (2018) Preparation and optimization of glyceryl behenate-based highly porous pellets containing cilostazol. Pharmaceutical Development and Technology 23:5, pages 540-551.
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Yvonne Rosiaux, Jean-Michel Girard, Florence Desvignes, Cédric Miolane & Delphine Marchaud. (2015) Optimizing a wet granulation process to obtain high-dose sustained-release tablets with Compritol 888 ATO. Drug Development and Industrial Pharmacy 41:10, pages 1738-1744.
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Matthew Roberts, Lia Pulcini, Shabbir Mostafa, Yvonne Cuppok-Rosiaux & Delphine Marchaud. (2015) Preparation and characterization of Compritol 888 ATO matrix tablets for the sustained release of diclofenac sodium. Pharmaceutical Development and Technology 20:4, pages 507-512.
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Matthew Roberts, Daniele Vellucci, Shabbir Mostafa, Cedric Miolane & Delphine Marchaud. (2012) Development and evaluation of sustained-release Compritol® 888 ATO matrix mini-tablets. Drug Development and Industrial Pharmacy 38:9, pages 1068-1076.
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T. Quinten, T. De Beer, A. Almeida, J. Vlassenbroeck, L. Van Hoorebeke, J.P. Remon & C. Vervaet. (2011) Development and evaluation of injection-molded sustained-release tablets containing ethylcellulose and polyethylene oxide. Drug Development and Industrial Pharmacy 37:2, pages 149-159.
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Na Chi, Ju Hong Guo, Yu Zhang, Wei Zhang & Xing Tang. (2010) An oral controlled release system for amroxol hydrochloride containing a wax and a water insoluble polymer. Pharmaceutical Development and Technology 15:1, pages 97-104.
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Chistopher R. Young, Michael Crowley, Caroline Dietzsch & James W. McGinity. (2007) Physicochemical properties of film-coated melt-extruded pellets. Journal of Microencapsulation 24:1, pages 57-71.
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C. R. Young, J. J. Koleng & J. W. McGinity. (2003) Properties of drug-containing spherical pellets produced by a hot-melt extrusion and spheronization process. Journal of Microencapsulation 20:5, pages 613-625.
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Yu-E Zhang & Joseph B. Schwartz. (2003) Melt Granulation and Heat Treatment for Wax Matrix-Controlled Drug Release. Drug Development and Industrial Pharmacy 29:2, pages 131-138.
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Ye Huang, Kavita H. Khanvilkar, Angela D. Moore & Marquetta Hilliard-Lott. (2003) Effects of Manufacturing Process Variables on In Vitro Dissolution Characteristics of Extended-Release Tablets Formulated with Hydroxypropyl Methylcellulose. Drug Development and Industrial Pharmacy 29:1, pages 79-88.
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Yvonne Rosiaux, Vincent Jannin, Sophie Hughes & Delphine Marchaud. 2015. Excipient Applications in Formulation Design and Drug Delivery. Excipient Applications in Formulation Design and Drug Delivery 237 271 .
Yvonne Rosiaux, Vincent Jannin, Sophie Hughes & Delphine Marchaud. (2014) Solid lipid excipients — Matrix agents for sustained drug delivery. Journal of Controlled Release 188, pages 18-30.
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N. Jedinger, J. Khinast & E. Roblegg. (2014) The design of controlled-release formulations resistant to alcohol-induced dose dumping – A review. European Journal of Pharmaceutics and Biopharmaceutics 87:2, pages 217-226.
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D.M. Patel, B.K. Patel, H.A. Patel & C.N. Patel. (2011) Design of Controlled Release Non-erodible Polymeric Matrix Tablet Using Microwave Oven-assisted Sintering Technique. Journal of Young Pharmacists 3:3, pages 176-180.
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Manish Ghimire, Lee Ann Hodges, Janet Band, Blythe Lindsay, Bridget O’Mahony, Fiona J. McInnes, Alexander B. Mullen & Howard N.E. Stevens. (2011) Correlation between in vitro and in vivo erosion behaviour of erodible tablets using gamma scintigraphy. European Journal of Pharmaceutics and Biopharmaceutics 77:1, pages 148-157.
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Shayne Cox GadA.K. Tiwary, Bharti Sapra & Subheet Jain. 2010. Pharmaceutical Sciences Encyclopedia. Pharmaceutical Sciences Encyclopedia.
B. S. Sudha, B. K. Sridhar & A. Srinatha. (2010) Modulation of Tramadol Release from a Hydrophobic Matrix: Implications of Formulations and Processing Variables. AAPS PharmSciTech 11:1, pages 433-440.
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Giacomo Di Colo, Ylenia Zambito, Andrea Baggiani, Vera Carelli & Maria Francesca Serafini. (2005) A site-specific controlled-release system for metformin. Journal of Pharmacy and Pharmacology 57:5, pages 565-571.
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Monica Rao, Anuradha Ranpise, Sameer Borate & Kaushik Thanki. (2009) Mechanistic Evaluation of the Effect of Sintering on Compritol® 888 ATO Matrices. AAPS PharmSciTech 10:2, pages 355-360.
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Thomas Quinten, Yves Gonnissen, Els Adriaens, Thomas De Beer, Veerle Cnudde, Bert Masschaele, Luc Van Hoorebeke, Juergen Siepmann, Jean Paul Remon & Chris Vervaet. (2009) Development of injection moulded matrix tablets based on mixtures of ethylcellulose and low-substituted hydroxypropylcellulose. European Journal of Pharmaceutical Sciences 37:3-4, pages 207-216.
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Reena Singh, S. S. Poddar & Amit Chivate. (2007) Sintering of wax for controlling release from pellets. AAPS PharmSciTech 8:3, pages E175-E183.
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S. Koennings, A. Berié, J. Tessmar, T. Blunk & A. Goepferich. (2007) Influence of wettability and surface activity on release behavior of hydrophilic substances from lipid matrices. Journal of Controlled Release 119:2, pages 173-181.
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Christopher R. Young, Caroline Dietzsch, Matteo Cerea, Thomas Farrell, Kurt A. Fegely, Ali Rajabi-Siahboomi & James W. McGinity. (2005) Physicochemical characterization and mechanisms of release of theophylline from melt-extruded dosage forms based on a methacrylic acid copolymer. International Journal of Pharmaceutics 301:1-2, pages 112-120.
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Michael M. Crowley, Britta Schroeder, Anke Fredersdorf, Sakae Obara, Mark Talarico, Shawn Kucera & James W. McGinity. (2004) Physicochemical properties and mechanism of drug release from ethyl cellulose matrix tablets prepared by direct compression and hot-melt extrusion. International Journal of Pharmaceutics 269:2, pages 509-522.
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