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Pharmaceutical Development and Technology Volume 5, 2000 - Issue 2
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Research Article

Granulation of Acetaminophen by a Rotating Fluidized-Bed Granulator

Takeshi Kawaguchi Faculty of Pharmacy, Meijo University, 150 Yagotoyama, Tempaku-ku, Nagoya, 468, Japan
,
Hisakazu Sunada Faculty of Pharmacy, Meijo University, 150 Yagotoyama, Tempaku-ku, Nagoya, 468, Japan
,
Yorinobu Yonezawa Faculty of Pharmacy, Meijo University, 150 Yagotoyama, Tempaku-ku, Nagoya, 468, Japan
,
Kazumi Danjo Faculty of Pharmacy, Meijo University, 150 Yagotoyama, Tempaku-ku, Nagoya, 468, Japan
,
Masaki Hasegawa Pharmaceutical Regulatory Affairs Center, Asahi Chemical Industry Co., Ltd., 632-1Mifuku, Ohito-cho, Tagata-gun, Shizuoka, 410-23, Japan
,
Tadashi Makino Pharmaceutical Development Laboratory, Takeda Chemical Industry Co., Ltd., 2-17-85 Jusohonmachi, Yodogawa-ku, Osaka, 532, Japan
,
Hiroshi Sakamoto Powder Technical Engineering Laboratory, Pow-rex Corporation, 8-121-1 Kitaitami, Itami, 664, Japan
,
Kanji Fujita Manufacturing Division, Kikusui Seisakusho Co., Ltd., 104 Minamikamiai-cho, Nishinokyo, Nakagyo-ku, Kyoto, 604, Japan
,
Tadatsugu Tanino Shionogi & Co., Ltd., 1-3 Kuise Terajima 2, Amagasaki, 660, Japan
&
Hiroyasu Kokubo Shin-Etsu Chemical Co., Ltd., 28-1 Nishifukushima kubiki-mura, Nakakubiki-gun, Niigata, 942, Japan
 show all
Pages 141-151 | Received 27 Jan 1998, Accepted 04 Aug 1999, Published online: 19 Apr 2000

Citations (10)

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Read on this site (2)

Firas Alshihabi, Thierry Vandamme & Gabriele Betz. (2013) Focused beam reflectance method as an innovative (PAT) tool to monitor in-line granulation process in fluidized bed. Pharmaceutical Development and Technology 18:1, pages 73-84.
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Zhi Hui Loh, Dawn ZL Er, Lai Wah Chan, Celine V Liew & Paul WS Heng. (2011) Spray granulation for drug formulation. Expert Opinion on Drug Delivery 8:12, pages 1645-1661.
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Articles from other publishers (8)

N. Hampel, E. Roydeva, A. Bück & E. Tsotsas. (2018) Coating of finely dispersed particles by two-fluid nozzle. Particuology 38, pages 80-93.
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Daniel To & Rajesh N. Davé. (2016) Fluid bed film coating of fine ibuprofen particles. Powder Technology 290, pages 102-113.
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Yoshihiro Hayashi, Takaya Sato & Makoto Otsuka. (2013) Real-Time Monitoring of the Drying of Extruded Granules in a Fluidised Bed Using near Infrared Spectroscopy and Kinetic Evaluation of the Drying Process. Journal of Near Infrared Spectroscopy 21:2, pages 107-115.
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Yoshinori Onuki, Shota Kawai, Hiroaki Arai, Jin Maeda, Keisuke Takagaki & Kozo Takayama. (2012) Contribution of the Physicochemical Properties of Active Pharmaceutical Ingredients to Tablet Properties Identified by Ensemble Artificial Neural Networks and Kohonen's Self-Organizing Maps. Journal of Pharmaceutical Sciences 101:7, pages 2372-2381.
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Masaki Hasegawa, Tadatsugu TaninoHisakazu Sunada. (2010) Study of Standard Formulation on Particle Design. Journal of the Society of Powder Technology, Japan 47:6, pages 402-411.
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Tomohiro HamashitaMiwako MatsuzakiTetsuo OnoMasaki OnoYoshinobu TsunenariTakao AketoSatoru Watano. (2008) Granulation of Core Particles Suitable for Film Coating by Agitation Fluidized Bed II. A Proposal of a Rapid Dissolution Test for Evaluation of Bitter Taste of Ibuprofen. Chemical and Pharmaceutical Bulletin 56:7, pages 883-887.
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Hirofumi Takeuchi, Shinsuke Nagira, Hiromitsu Yamamoto & Yoshiaki Kawashima. (2004) Die wall pressure measurement for evaluation of compaction property of pharmaceutical materials. International Journal of Pharmaceutics 274:1-2, pages 131-138.
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Tetsuya Ozeki, Hideyo Katsuyama, Yuriko Yasuzawa, Yuuki Takashima, Takahide Kasai, Takahiro Eguchi, Hisaya Kakiuchi, Hiroshi Yuasa & Hiroaki Okada. (2003) Acid-treated yeast cell wall as a binder displaying function of disintegrant. AAPS PharmSciTech 4:3, pages 94-100.
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