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Research Article

Moisture Uptake and Its Influence on Pressurized Metered-Dose Inhalers

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Pages 153-162 | Received 28 Jan 1999, Accepted 04 Aug 1999, Published online: 19 Apr 2000

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Ebtsam M. Abdou, Soha M. Kandil, Amany Morsi & Maysa W. Sleem. (2019) In-vitro and in-vivo respiratory deposition of a developed metered dose inhaler formulation of an anti-migraine drug. Drug Delivery 26:1, pages 689-699.
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Bing Zhu, Daniela Traini & Paul Young. (2015) Aerosol particle generation from solution-based pressurized metered dose inhalers: a technical overview of parameters that influence respiratory deposition. Pharmaceutical Development and Technology 20:8, pages 897-910.
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Jesslynn Ooi, Daniela Traini, Ben J Boyd, Simon Gaisford & Paul M Young. (2015) Determination of physical and chemical stability in pressurised metered dose inhalers: potential new techniques. Expert Opinion on Drug Delivery 12:10, pages 1661-1675.
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Saburo Murata, Takashi Izumi & Hideki Ito. (2013) Reformulation of Stmerin® D CFC formulation using HFA propellants. Pharmaceutical Development and Technology 18:6, pages 1314-1318.
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Kevin P. O’Donnell & Robert O. Williams$suffix/text()$suffix/text(). (2013) Pulmonary dispersion formulations: The impact of dispersed powder properties on pressurized metered dose inhaler stability. Drug Development and Industrial Pharmacy 39:3, pages 413-424.
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Natalia A. Geppe, Elena G. Kondiurina, Vera A. Reviakina, Aleksandr B. Malakhov & Natalia G. Kolosova. (2021) Therapy of bronchial asthma in children: age-related aspects. Pediatrics. Consilium Medicum:2, pages 113-122.
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Anthony J. Hickey. 2018. Inhaled Pharmaceutical Product Development Perspectives. Inhaled Pharmaceutical Product Development Perspectives 15 31 .
Yang Chen, Paul M. Young, David F. Fletcher, Hak Kim Chan, Edward Long, David Lewis, Tanya Church & Daniela Traini. (2014) The Effect of Actuator Nozzle Designs on the Electrostatic Charge Generated in Pressurised Metered Dose Inhaler Aerosols. Pharmaceutical Research 32:4, pages 1237-1248.
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Dexter J. D’Sa, David Lechuga-Ballesteros & Hak-Kim Chan. (2014) Isothermal Microcalorimetry of Pressurized Systems II: Effect of Excipient and Water Ingress on Formulation Stability of Amorphous Glycopyrrolate. Pharmaceutical Research 32:2, pages 714-722.
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Gaia Colombo, Chiara Parlati & Paola Russo. 2013. Inhalation Drug Delivery. Inhalation Drug Delivery 145 168 .
Sandro R. P. da Rocha, Balaji Bharatwaj & Sowmya Saiprasad. 2011. Controlled Pulmonary Drug Delivery. Controlled Pulmonary Drug Delivery 165 201 .
Shayne Cox GadMichael Hindle. 2010. Pharmaceutical Sciences Encyclopedia. Pharmaceutical Sciences Encyclopedia.
Philip Chi Lip Kwok, Tim Noakes & Hak-Kim Chan. (2008) Effect of moisture on the electrostatic charge properties of metered dose inhaler aerosols. Journal of Aerosol Science 39:3, pages 211-226.
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ERIK MOGALIAN & PAUL BRIAN MYRDAL. 2007. Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics. Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics 427 441 .
Hugh Smyth. 2006. Excipient Development for Pharmaceutical, Biotechnology, and Drug Delivery Systems. Excipient Development for Pharmaceutical, Biotechnology, and Drug Delivery Systems 225 249 .
Eric Derom & Romain A Pauwels. (2005) Pharmacokinetic and Pharmacodynamic Properties of Inhaled Beclometasone Dipropionate Delivered Via Hydrofluoroalkane-Containing Devices. Clinical Pharmacokinetics 44:8, pages 815-836.
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Latarsha Jones, Lucila Garcia-Contreras, Hugh Smyth, Robert Garmise, Anthony Hickey & Daniel Cooney. 2004. Aerosols Handbook. Aerosols Handbook 260 284 .

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