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Molecular and Cellular Biology Volume 34, 2014 - Issue 20
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Article

Syk Interacts with and Phosphorylates Nucleolin To Stabilize Bcl-xL mRNA and Promote Cell Survival

Wen-Horng Wanga Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana, USA
,
Michael O. Childressb Department of Veterinary Clinical Sciences, Purdue University, West Lafayette, Indiana, USA;c Purdue Center for Cancer Research, Purdue University, West Lafayette, Indiana, USA
&
Robert L. Geahlena Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana, USA;c Purdue Center for Cancer Research, Purdue University, West Lafayette, Indiana, USACorrespondence[email protected]
Pages 3788-3799 | Received 14 Jul 2014, Accepted 28 Jul 2014, Published online: 20 Mar 2023

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Sojin Park, Ju-Won Jang & Eun-Yi Moon. (2018) Spleen tyrosine kinase-dependent Nrf2 activation regulates oxidative stress-induced cell death in WiL2-NS human B lymphoblasts. Free Radical Research 52:9, pages 977-987.
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Articles from other publishers (17)

Marion Buffard, Aurélien Naldi, Gilles Freiss, Marcel Deckert, Ovidiu Radulescu, Peter J. Coopman & Romain M. Larive. (2021) Comparison of SYK Signaling Networks Reveals the Potential Molecular Determinants of Its Tumor-Promoting and Suppressing Functions. Biomolecules 11:2, pages 308.
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Laura Sofia Carvalho, Nélio Gonçalves, Nuno André Fonseca & João Nuno Moreira. (2021) Cancer Stem Cells and Nucleolin as Drivers of Carcinogenesis. Pharmaceuticals 14:1, pages 60.
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Sojin Park, Ju-Won Jang & Eun-Yi Moon. (2020) BAFF attenuates oxidative stress-induced cell death by the regulation of mitochondria membrane potential via Syk activation in WiL2-NS B lymphoblasts. Scientific Reports 10:1.
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Chao Feng, Amitava Roy & Carol Beth Post. (2018) Entropic allostery dominates the phosphorylation-dependent regulation of Syk tyrosine kinase release from immunoreceptor tyrosine-based activation motifs. Protein Science 27:10, pages 1780-1796.
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Yingchun Qiao, Xixi Tian, Li Men, Shengyu Li, Yufeng Chen, Meiting Xue, Yahui Hu, Pengfei Zhou, Guangfeng Long, Yue Shi, Ruiqing Liu, Yunde Liu, Zhi Qi, Yujie Cui & Yanna Shen. (2018) Spleen tyrosine kinase promotes NLR family pyrin domain containing 3 inflammasome‑mediated IL‑1β secretion via c‑Jun N‑terminal kinase activation and cell apoptosis during diabetic nephropathy. Molecular Medicine Reports.
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Jia Cui & William Placzek. (2018) Post-Transcriptional Regulation of Anti-Apoptotic BCL2 Family Members. International Journal of Molecular Sciences 19:1, pages 308.
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Iva Ugrinova, Maria Petrova, Mounira Chalabi-Dchar & Philippe Bouvet. 2018. Protein-Protein Interactions in Human Disease, Part B. Protein-Protein Interactions in Human Disease, Part B 133 164 .
Mariangela Librizzi, Fabio Caradonna, Ilenia Cruciata, Janusz Dębski, Supojjanee Sansook, Michał Dadlez, John Spencer & Claudio Luparello. (2017) Molecular Signatures Associated with Treatment of Triple-Negative MDA-MB231 Breast Cancer Cells with Histone Deacetylase Inhibitors JAHA and SAHA. Chemical Research in Toxicology 30:12, pages 2187-2196.
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Nirmalya Dasgupta, Bhupesh Kumar Thakur, Atri Ta, Pujarini Dutta & Santasabuj Das. (2017) Suppression of Spleen Tyrosine Kinase (Syk) by Histone Deacetylation Promotes, Whereas BAY61-3606, a Synthetic Syk Inhibitor Abrogates Colonocyte Apoptosis by ERK Activation. Journal of Cellular Biochemistry 118:1, pages 191-203.
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Jeff Sharman & Julie Di Paolo. (2016) Targeting B-cell receptor signaling kinases in chronic lymphocytic leukemia: the promise of entospletinib. Therapeutic Advances in Hematology 7:3, pages 157-170.
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Mariya O. Krisenko, Reneé L. Higgins, Soumitra Ghosh, Qing Zhou, Joy S. Trybula, Wen-Horng Wang & Robert L. Geahlen. (2015) Syk Is Recruited to Stress Granules and Promotes Their Clearance through Autophagy. Journal of Biological Chemistry 290:46, pages 27803-27815.
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Soumitra Ghosh & Robert L. Geahlen. (2015) Stress Granules Modulate SYK to Cause Microglial Cell Dysfunction in Alzheimer's Disease. EBioMedicine 2:11, pages 1785-1798.
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Yu Yu, Stephanie Gaillard, Jude M. Phillip, Tai-Chung Huang, Sneha M. Pinto, Nayara G. Tessarollo, Zhen Zhang, Akhilesh Pandey, Denis Wirtz, Ayse Ayhan, Ben Davidson, Tian-Li Wang & Ie-Ming Shih. (2015) Inhibition of Spleen Tyrosine Kinase Potentiates Paclitaxel-Induced Cytotoxicity in Ovarian Cancer Cells by Stabilizing Microtubules. Cancer Cell 28:1, pages 82-96.
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Mandy Muller, Stephanie Hutin, Oliver Marigold, Kathy H. Li, Al Burlingame & Britt A. Glaunsinger. (2015) A Ribonucleoprotein Complex Protects the Interleukin-6 mRNA from Degradation by Distinct Herpesviral Endonucleases. PLOS Pathogens 11:5, pages e1004899.
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Zhong-Jian Shen & James Malter. (2015) Regulation of AU-Rich Element RNA Binding Proteins by Phosphorylation and the Prolyl Isomerase Pin1. Biomolecules 5:2, pages 412-434.
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Mariya O. Krisenko & Robert L. Geahlen. (2015) Calling in SYK: SYK's dual role as a tumor promoter and tumor suppressor in cancer. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1853:1, pages 254-263.
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Fatih M. Uckun, Hong Ma, Zahide Ozer, Patricia Goodman, Jian Zhang & Sanjive Qazi. (2014) A Previously Unknown Unique Challenge for Inhibitors of SYK ATP-Binding Site: Role of SYK as A Cell Cycle Checkpoint Regulator. EBioMedicine 1:1, pages 16-28.
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