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Molecular and Cellular Biology Volume 34, 2014 - Issue 10
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Article

The Tumor Suppressor PML Specifically Accumulates at RPA/Rad51-Containing DNA Damage Repair Foci but Is Nonessential for DNA Damage-Induced Fibroblast Senescence

Sandra Müncha Leibniz Institute for Age Research, Jena, Germany
,
Stefanie Weidtkamp-Petersa Leibniz Institute for Age Research, Jena, Germany
,
Karolin Klementa Leibniz Institute for Age Research, Jena, Germany
,
Paulius Grigaraviciusa Leibniz Institute for Age Research, Jena, Germany
,
Shamci Monajembashia Leibniz Institute for Age Research, Jena, Germany
,
Paolo Salomonib University College London, UCL Cancer Institute, London, United Kingdom
,
Pier Paolo Pandolfic Cancer Research Institute, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
,
Klaus Weißhartd Carl Zeiss Microscopy GmbH, BioSciences Division, Jena, Germany
&
Peter Hemmericha Leibniz Institute for Age Research, Jena, GermanyCorrespondence[email protected]
 show all
Pages 1733-1746 | Received 08 Oct 2013, Accepted 14 Feb 2014, Published online: 20 Mar 2023

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Michael Rosemann & Michael Atkinson. (2015) Spots, Damn'd spots and γH2AX foci. Cell Cycle 14:7, pages 947-947.
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Terezie Hornofova, Barbora Pokorna, Sona Stemberkova Hubackova, Alena Uvizl, Jan Kosla, Jiri Bartek, Zdenek Hodny & Pavla Vasicova. (2022) Phospho-SIM and exon8b of PML protein regulate formation of doxorubicin-induced rDNA-PML compartment. DNA Repair 114, pages 103319.
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Jianchun Wu & David L. Crowe. (2021) PARP5B is required for nonhomologous end joining during tumorigenesis in vivo. Molecular Carcinogenesis 61:1, pages 85-98.
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Nicole Schwab, YoungJun Ju & Lili-Naz Hazrati. (2021) Early onset senescence and cognitive impairment in a murine model of repeated mTBI. Acta Neuropathologica Communications 9:1.
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Kathleen M. AttwoodJayme SalsmanDudley ChungSabateeshan MathavarajahCarter Van IderstineGraham Dellaire. (2020) PML isoform expression and DNA break location relative to PML nuclear bodies impacts the efficiency of homologous recombination. Biochemistry and Cell Biology 98:3, pages 314-326.
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Marketa Vancurova, Hana Hanzlikova, Lucie Knoblochova, Jan Kosla, Dusana Majera, Martin Mistrik, Kamila Burdova, Zdenek Hodny & Jiri Bartek. (2019) PML nuclear bodies are recruited to persistent DNA damage lesions in an RNF168-53BP1 dependent manner and contribute to DNA repair. DNA Repair 78, pages 114-127.
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Robert J. Pignolo, Rebekah M. Samsonraj, Susan F. Law, Haitao Wang & Abhishek Chandra. (2019) Targeting Cell Senescence for the Treatment of Age-Related Bone Loss. Current Osteoporosis Reports 17:2, pages 70-85.
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Christian Hoischen, Shamci Monajembashi, Klaus Weisshart & Peter Hemmerich. (2018) Multimodal Light Microscopy Approaches to Reveal Structural and Functional Properties of Promyelocytic Leukemia Nuclear Bodies. Frontiers in Oncology 8.
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Hae Ryung Chang, Anudari Munkhjargal, Myung-Jin Kim, Seon Young Park, Eunyoung Jung, Jae-Ha Ryu, Young Yang, Jong-Seok Lim & Yonghwan Kim. (2018) The functional roles of PML nuclear bodies in genome maintenance. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 809, pages 99-107.
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Edwige Voisset, Eva MoravcsikEva W. StratfordAmie JayeChristopher J. PalgraveRobert K. HillsPaolo Salomoni, Scott C. Kogan, Ellen SolomonDavid Grimwade. (2018) Pml nuclear body disruption cooperates in APL pathogenesis and impairs DNA damage repair pathways in mice. Blood 131:6, pages 636-648.
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Soňa Legartová, Petra Sehnalová, Barbora Malyšková, Thomas Küntziger, Philippe Collas, Dušan Cmarko, Ivan Raška, Dmitry V. Sorokin, Stanislav Kozubek & Eva Bártová. (2016) Localized Movement and Levels of 53BP1 Protein Are Changed by γ-irradiation in PML Deficient Cells. Journal of Cellular Biochemistry 117:11, pages 2583-2596.
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A di Masi, D Cilli, F Berardinelli, A Talarico, I Pallavicini, R Pennisi, S Leone, A Antoccia, N I Noguera, F Lo-Coco, P Ascenzi, S Minucci & C Nervi. (2016) PML nuclear body disruption impairs DNA double-strand break sensing and repair in APL. Cell Death & Disease 7:7, pages e2308-e2308.
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Eleonora Croco, Silvia Marchionni & Antonello Lorenzini. (2016) Genetic instability and aging under the scrutiny of comparative biology: a meta-analysis of spontaneous micronuclei frequency. Mechanisms of Ageing and Development 156, pages 34-41.
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S. Marthandan, M. Baumgart, S. Priebe, M. Groth, J. Schaer, C. Kaether, R. Guthke, A. Cellerino, M. Platzer, S. Diekmann & P. Hemmerich. (2016) Conserved Senescence Associated Genes and Pathways in Primary Human Fibroblasts Detected by RNA-Seq. PLOS ONE 11:5, pages e0154531.
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Alkmini Kalousi & Evi Soutoglou. (2016) Nuclear compartmentalization of DNA repair. Current Opinion in Genetics & Development 37, pages 148-157.
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Jordan Pinder, Alkmini Kalousi, Evi Soutoglou & Graham Dellaire. 2016. The Functional Nucleus. The Functional Nucleus 239 257 .
Jan O. Nehlin. 2016. Cellular Ageing and Replicative Senescence. Cellular Ageing and Replicative Senescence 203 239 .
Shiva Marthandan, Steffen Priebe, Marco Groth, Reinhard Guthke, Matthias Platzer, Peter Hemmerich & Stephan Diekmann. (2015) Hormetic effect of rotenone in primary human fibroblasts. Immunity & Ageing 12:1.
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Shiva Marthandan. (2015) Effects of ebselen and N-acetyl cysteine on replicative aging of primary human fibroblast strains. Immunity & Ageing 12:1.
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D T Warren, T Tajsic, L J Porter, R M Minaisah, A Cobb, A Jacob, D Rajgor, Q P Zhang & C M Shanahan. (2015) Nesprin-2-dependent ERK1/2 compartmentalisation regulates the DNA damage response in vascular smooth muscle cell ageing. Cell Death & Differentiation 22:9, pages 1540-1550.
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Penelope Kroustallaki & Sarantis Gagos. 2015. Genomic Elements in Health, Disease and Evolution. Genomic Elements in Health, Disease and Evolution 247 283 .
Karolin Klement & Aaron A. Goodarzi. (2014) DNA double strand break responses and chromatin alterations within the aging cell. Experimental Cell Research 329:1, pages 42-52.
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