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Neurological Research
A Journal of Progress in Neurosurgery, Neurology and Neurosciences
Volume 37, 2015 - Issue 2
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Current evidence of temozolomide and bevacizumab in treatment of gliomas

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Clarissa A. Whitehead, Andrew H. Kaye, Katharine J. Drummond, Samuel S. Widodo, Theo Mantamadiotis, Laura J. Vella & Stanley S. Stylli. (2020) Extracellular vesicles and their role in glioblastoma. Critical Reviews in Clinical Laboratory Sciences 57:4, pages 227-252.
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Tongxia Zhang, Jie Chai & Lingyi Chi. (2019) Induction Of XLF And 53BP1 Expression Is Associated With Temozolomide Resistance In Glioblastoma Cells. OncoTargets and Therapy 12, pages 10139-10151.
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Yichun He, Jing Su, Beiwu Lan, Yufei Gao & Jingxia Zhao. (2019) Targeting off-target effects: endoplasmic reticulum stress and autophagy as effective strategies to enhance temozolomide treatment. OncoTargets and Therapy 12, pages 1857-1865.
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Shibo Duan, Ming Li, Zhifeng Wang, Longlong Wang & Yongjie Liu. (2018) H19 induced by oxidative stress confers temozolomide resistance in human glioma cells via activating NF-κB signaling. OncoTargets and Therapy 11, pages 6395-6404.
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Clara Di Vito, Stefania Elena Navone, Giovanni Marfia, Loubna Abdel Hadi, Maria Elisa Mancuso, Alessandro Pecci, Francesco Maria Crisà, Valeria Berno, Paolo Rampini, Rolando Campanella & Laura Riboni. (2017) Platelets from glioblastoma patients promote angiogenesis of tumor endothelial cells and exhibit increased VEGF content and release. Platelets 28:6, pages 585-594.
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Liliana R. Oancea-Castillo, Carmen Klein, Amir Abdollahi, Klaus-Josef Weber, Anne Régnier-Vigouroux & Ivana Dokic. (2017) Comparative analysis of the effects of a sphingosine kinase inhibitor to temozolomide and radiation treatment on glioblastoma cell lines. Cancer Biology & Therapy 18:6, pages 400-406.
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Danop Nanegrungsunk, Nattayaporn Apaijai, Chontida Yarana, Jirapas Sripetchwandee, Kriengsak Limpastan, Wanarak Watcharasaksilp, Tanat Vaniyapong, Nipon Chattipakorn & Siriporn C Chattipakorn. (2016) Bevacizumab is superior to Temozolomide in causing mitochondrial dysfunction in human brain tumors. Neurological Research 38:4, pages 285-293.
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Articles from other publishers (34)

Kun Deng & Minghua Wu. (2023) Leucine-rich repeats containing 4 protein (LRRC4) in memory, psychoneurosis, and glioblastoma. Chinese Medical Journal 136:1, pages 4-12.
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Anagha Acharekar, Ketaki Bachal, Pallavi Shirke, Rahul Thorat, Archisman Banerjee, Nilesh Gardi, Abhijit Majumder & Shilpee Dutt. (2023) Substrate stiffness regulates the recurrent glioblastoma cell morphology and aggressiveness. Matrix Biology 115, pages 107-127.
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Lianxin Li, Zhihao Yang, Yinfei Zheng, Zhigang Chen, Xiaoyu Yue, Erbao Bian & Bing Zhao. (2022) Identification of an endoplasmic reticulum stress-related signature associated with clinical prognosis and immune therapy in glioma. BMC Neurology 22:1.
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Shao-Wei Feng, Pei-Chi Chang, Hsuan-Yu Chen, Dueng-Yuan Hueng, Yao-Feng Li & Shih-Ming Huang. (2022) Exploring the Mechanism of Adjuvant Treatment of Glioblastoma Using Temozolomide and Metformin. International Journal of Molecular Sciences 23:15, pages 8171.
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João Victor Roza Cruz, Carolina Batista, Bernardo de Holanda Afonso, Magna Suzana Alexandre-Moreira, Luiz Gustavo Dubois, Bruno Pontes, Vivaldo Moura Neto & Fabio de Almeida Mendes. (2022) Obstacles to Glioblastoma Treatment Two Decades after Temozolomide. Cancers 14:13, pages 3203.
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Stella Sun, Karrie Kiang & Gilberto Leung. (2022) Chaperone protein P4HB predicts temozolomide response and prognosis in malignant glioma. Oncology Letters 24:2.
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Jubo Wang, Yu Quan, Jian Lv, Shouping Gong & Pengyu Ren. (2022) Inhibition of FAM83D displays antitumor effects in glioblastoma via down‐regulation of the AKT /Wnt/β‐catenin pathway . Environmental Toxicology 37:6, pages 1343-1356.
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Hanren Chen & Jian Wen. (2022) Iron oxide nanoparticles loaded with paclitaxel inhibits glioblastoma by enhancing autophagy-dependent ferroptosis pathway. European Journal of Pharmacology 921, pages 174860.
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Yao-Min Li, Li-Hui Meng, Yan-Ru Hu, Tian-Tian Zhang, Zheng-Nan Su, Zhi-Yuan Ouyang, Wen-Chao Li, Jiang-Ling Wan & Qing-Zhi Wu. (2022) Suppression mechanisms on proliferation of glioma U251 cells by FePt nanoparticles through intracellular oxidative stress. Rare Metals 41:4, pages 1202-1209.
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Fernanda Bueno Morrone, Pedro Vargas, Liliana Rockenbach & Thamiris Becker Scheffel. (2021) P2Y12 Purinergic Receptor and Brain Tumors: Implications on Glioma Microenvironment. Molecules 26:20, pages 6146.
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Preantha Poonan, Clement Agoni, Mahmoud A. A. Ibrahim & Mahmoud E. S. Soliman. (2021) Glioma-Targeted Therapeutics: Computer-Aided Drug Design Prospective. The Protein Journal 40:5, pages 601-655.
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Ana Laura V. Alves, Izabela N. F. Gomes, Adriana C. Carloni, Marcela N. Rosa, Luciane S. da Silva, Adriane F. Evangelista, Rui Manuel Reis & Viviane Aline O. Silva. (2021) Role of glioblastoma stem cells in cancer therapeutic resistance: a perspective on antineoplastic agents from natural sources and chemical derivatives. Stem Cell Research & Therapy 12:1.
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S. Daisy Precilla, Shreyas S. Kuduvalli & Anitha Thirugnanasambandhar Sivasubramanian. (2020) Disentangling the therapeutic tactics in GBM: From bench to bedside and beyond. Cell Biology International 45:1, pages 18-53.
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Qiao-Li Lv, Li-Chong Wang, Dang-Chi Li, Qian-Xia Lin, Xiao-Li Shen, Hai-Yun Liu, Min Li, Yu-Long Ji, Chong-Zhen Qin & Shu-Hui Chen. (2020) Knockdown lncRNA DLEU1 Inhibits Gliomas Progression and Promotes Temozolomide Chemosensitivity by Regulating Autophagy. Frontiers in Pharmacology 11.
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Xiaoqin Ma, Meixiang Yu, Chenxia Hao & Wanhua Yang. (2020) Shikonin induces tumor apoptosis in glioma cells via endoplasmic reticulum stress, and Bax/Bak mediated mitochondrial outer membrane permeability. Journal of Ethnopharmacology 263, pages 113059.
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Beibei Zhai, Yue Li, Sudha Sravanti Kotapalli, Jeffrey Bacha, Dennis Brown, Anne Steinø & Mads Daugaard. (2020) Dianhydrogalactitol synergizes with topoisomerase poisons to overcome DNA repair activity in tumor cells. Cell Death & Disease 11:7.
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Jianbo Feng, Yan Zhang, Xing Ren, Di Li, Haijuan Fu, Changhong Liu, Wen Zhou, Qing Liu, Qiang Liu & Minghua Wu. (2020) Leucine-rich repeat containing 4 act as an autophagy inhibitor that restores sensitivity of glioblastoma to temozolomide. Oncogene 39:23, pages 4551-4566.
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Mohammad Norouzi. (2020) Gold Nanoparticles in Glioma Theranostics. Pharmacological Research 156, pages 104753.
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Zhi-peng Wen, Wen-jing Zeng, Yan-hong Chen, He Li, Jie-ya Wang, Quan Cheng, Jing Yu, Hong-hao Zhou, Zheng-zheng Liu, Jian Xiao & Xiao-ping Chen. (2019) Knockdown ATG4C inhibits gliomas progression and promotes temozolomide chemosensitivity by suppressing autophagic flux. Journal of Experimental & Clinical Cancer Research 38:1.
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Moumita Kundu, Subhayan Das, Dibakar Dhara & Mahitosh Mandal. (2019) Prospect of natural products in glioma: A novel avenue in glioma management. Phytotherapy Research 33:10, pages 2571-2584.
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Jiancun Wang, Guancheng Hu & Xingyun Quan. (2019) Analysis of the factors affecting the prognosis of glioma patients. Open Medicine 14:1, pages 331-335.
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Ming-Chung Lin, Yuan-Wen Lee, Yuan-Yun Tseng, Yung-Wei Lin, Jui-Tai Chen, Shing-Hwa Liu & Ruei-Ming Chen. (2019) Honokiol Induces Autophagic Apoptosis in Neuroblastoma Cells through a P53-Dependent Pathway. The American Journal of Chinese Medicine 47:04, pages 895-912.
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Elzbieta Pawlowska, Joanna Szczepanska, Magdalena Szatkowska & Janusz Blasiak. (2018) An Interplay between Senescence, Apoptosis and Autophagy in Glioblastoma Multiforme—Role in Pathogenesis and Therapeutic Perspective. International Journal of Molecular Sciences 19:3, pages 889.
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Shabierjiang JIAPAER, Takuya FURUTA, Shingo TANAKA, Tomohiro KITABAYASHI & Mitsutoshi NAKADA. (2018) Potential Strategies Overcoming the Temozolomide Resistance for Glioblastoma. Neurologia medico-chirurgica 58:10, pages 405-421.
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Chunming Jiang, Fang Shen, Jianmin Du, Xiang Fang, Xiaoli Li, Jin Su, Xiaohua Wang, Xianmei Huang & Zhangli Liu. (2018) Upregulation of CASC2 sensitized glioma to temozolomide cytotoxicity through autophagy inhibition by sponging miR-193a-5p and regulating mTOR expression. Biomedicine & Pharmacotherapy 97, pages 844-850.
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Feng Jin, Guang-Kui Han, Hao Zhang, Ran Zhang, Gen-Hua Li, Song Feng, Xian-Yun Qin, Ling-Sheng Kong, Quan-Min Nie, Hua-Rong Li & Lei Zhao. (2017) Difference in the Inhibitory Effect of Temozolomide on TJ905 Glioma Cells and Stem Cells. Frontiers in Neurology 8.
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Lin Shi, Hongyuan Li & Yang Zhan. (2017) All-trans retinoic acid enhances temozolomide-induced autophagy in human glioma cells U251 via targeting Keap1/Nrf2/ARE signaling pathway. Oncology Letters 14:3, pages 2709-2714.
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Sean Mahase, Rachel N. Rattenni, Pieter Wesseling, William Leenders, Clarissa Baldotto, Rajan Jain & David Zagzag. (2017) Hypoxia-Mediated Mechanisms Associated with Antiangiogenic Treatment Resistance in Glioblastomas. The American Journal of Pathology 187:5, pages 940-953.
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Bor-Chin Cheng, Jui-Tai Chen, Shun-Tai Yang, Chung-ching Chio, Shing-Hwa Liu & Ruei-Ming Chen. (2017) Cobalt chloride treatment induces autophagic apoptosis in human glioma cells via a p53-dependent pathway. International Journal of Oncology 50:3, pages 964-974.
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Yuanliang Yan, Zhijie Xu, Shuang Dai, Long Qian, Lunquan Sun & Zhicheng Gong. (2016) Targeting autophagy to sensitive glioma to temozolomide treatment. Journal of Experimental & Clinical Cancer Research 35:1.
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Jiahao Su, Meiqin Cai, Wensheng Li, Bo Hou, Haiyong He, Cong Ling, Tengchao Huang, Huijiao Liu & Ying Guo. (2016) Molecularly Targeted Drugs Plus Radiotherapy and Temozolomide Treatment for Newly Diagnosed Glioblastoma: A Meta-Analysis and Systematic Review. Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics 24:2, pages 117-128.
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Monika Paul-Samojedny, Adam Pudełko, Małgorzata Kowalczyk, Anna Fila-Daniłow, Renata Suchanek-Raif, Paulina Borkowska & Jan Kowalski. (2016) Combination Therapy with AKT3 and PI3KCA siRNA Enhances the Antitumor Effect of Temozolomide and Carmustine in T98G Glioblastoma Multiforme Cells. BioDrugs 30:2, pages 129-144.
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Michael Iv, Nicholas Telischak, Dan Feng, Samantha J Holdsworth, Kristen W Yeom & Heike E Daldrup-Link. (2015) Clinical applications of iron oxide nanoparticles for magnetic resonance imaging of brain tumors. Nanomedicine 10:6, pages 993-1018.
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Eivind A. Segtnan, Søren Hess, Peter Grupe & Poul Flemming Høilund-Carlsen. (2015) 18F-Fluorodeoxyglucose PET/Computed Tomography for Primary Brain Tumors. PET Clinics 10:1, pages 59-73.
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