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Research Article

Inspiratory flow rates and volumes with the Aerolizer dry powder inhaler in asthmatic children and adults

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Pages 131-137 | Accepted 10 Oct 2004, Published online: 03 Nov 2004

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Todor A. Popov, Sophie De Niet & Francis Vanderbist. (2016) Budesonide/salmeterol in fixed-dose combination for the treatment of asthma. Expert Review of Respiratory Medicine 10:2, pages 113-125.
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Bruce M Prenner. (2007) Formoterol dry-powder inhaler for the treatment of asthma and chronic obstructive pulmonary disease. Expert Opinion on Pharmacotherapy 8:17, pages 3069-3084.
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Mathieu Molimard, Denise Till, Stephan Stenglein, Dilraj Singh & Markus Krummen. (2007) Inhalation devices for long-acting β2-agonists: efficiency and ease of use of dry powder formoterol inhalers for use by patients with asthma and COPD. Current Medical Research and Opinion 23:10, pages 2405-2413.
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Articles from other publishers (28)

Henry ChrystynWahida AzouzWalid Tarsin. (2023) Dry Powder Inhalers: From Bench to Bedside. Journal of Aerosol Medicine and Pulmonary Drug Delivery.
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Wei-Ren Ke, Philip Chi Lip Kwok, Dipesh Khanal, Rachel Yoon Kyung Chang & Hak-Kim Chan. (2021) Co-spray dried hydrophobic drug formulations with crystalline lactose for inhalation aerosol delivery. International Journal of Pharmaceutics 602, pages 120608.
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Wei-Ren Ke, Rachel Yoon Kyung Chang, Philip Chi Lip Kwok, Donghao Chen & Hak-Kim Chan. (2020) Spray drying lactose from organic solvent suspensions for aerosol delivery to the lungs. International Journal of Pharmaceutics 591, pages 119984.
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S. Sommerfeld Ross, S. Gharse, L. Sanchez & J. Fiegel. (2017) Dry powder aerosols to co-deliver antibiotics and nutrient dispersion compounds for enhanced bacterial biofilm eradication. International Journal of Pharmaceutics 531:1, pages 14-23.
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Thaigarajan Parumasivam, Rachel Yoon Kyung Chang, Sharif Abdelghany, Tian Tian Ye, Warwick John Britton & Hak-Kim Chan. (2016) Dry powder inhalable formulations for anti-tubercular therapy. Advanced Drug Delivery Reviews 102, pages 83-101.
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David PrimeWilfried de BackerMelanie HamiltonAnthony CahnAndrew PreeceDennis KelleherAmanda BainesAlison MooreNoushin BrealeyJackie Moynihan. (2015) Effect of Disease Severity in Asthma and Chronic Obstructive Pulmonary Disease on Inhaler-Specific Inhalation Profiles Through the ELLIPTA ® Dry Powder Inhaler . Journal of Aerosol Medicine and Pulmonary Drug Delivery 28:6, pages 486-497.
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Ahmed O. Shalash, Abdulla M. Molokhia & Mustafa M.A. Elsayed. (2015) Insights into the roles of carrier microstructure in adhesive/carrier-based dry powder inhalation mixtures: Carrier porosity and fine particle content. European Journal of Pharmaceutics and Biopharmaceutics 96, pages 291-303.
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Zhenbo Tong, Hidehiro Kamiya, Aibing Yu, Hak-Kim Chan & Runyu Yang. (2014) Multi-Scale Modelling of Powder Dispersion in a Carrier-Based Inhalation System. Pharmaceutical Research 32:6, pages 2086-2096.
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Wahida AzouzPhilip ChetcutiHarold S.R. HoskerDinesh SaralayaJohn StephensonHenry Chrystyn. (2015) The Inhalation Characteristics of Patients When They Use Different Dry Powder Inhalers. Journal of Aerosol Medicine and Pulmonary Drug Delivery 28:1, pages 35-42.
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Sandra Lindert, Antje Below & Joerg Breitkreutz. (2014) Performance of Dry Powder Inhalers with Single Dosed Capsules in Preschool Children and Adults Using Improved Upper Airway Models. Pharmaceutics 6:1, pages 36-51.
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S. Weber, A. Zimmer & J. Pardeike. (2014) Solid Lipid Nanoparticles (SLN) and Nanostructured Lipid Carriers (NLC) for pulmonary application: A review of the state of the art. European Journal of Pharmaceutics and Biopharmaceutics 86:1, pages 7-22.
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Darragh Murnane & Marc B. Brown. 2014. Pediatric Formulations. Pediatric Formulations 253 272 .
Suzanne M. D’Addio, John Gar Yan Chan, Philip Chi Lip Kwok, Bryan R. Benson, Robert K. Prud’homme & Hak-Kim Chan. (2013) Aerosol Delivery of Nanoparticles in Uniform Mannitol Carriers Formulated by Ultrasonic Spray Freeze Drying. Pharmaceutical Research 30:11, pages 2891-2901.
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Z.B. Tong, B. Zheng, R.Y. Yang, A.B. Yu & H.K. Chan. (2013) CFD-DEM investigation of the dispersion mechanisms in commercial dry powder inhalers. Powder Technology 240, pages 19-24.
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Gabriela Apiou-SbirleaSteve Newman, John Fleming, Ruediger Siekmeier, Stephan Ehrmann, Gerhard Scheuch, Guenther Hochhaus & Anthony Hickey. (2013) Bioequivalence of inhaled drugs: fundamentals, challenges and perspectives. Therapeutic Delivery 4:3, pages 343-367.
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Christopher J Cates & Matthew J Cates. (2012) Regular treatment with formoterol for chronic asthma: serious adverse events. Cochrane Database of Systematic Reviews.
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Martin J. Donovan, Sin Hyen Kim, Venkatramanan Raman & Hugh D. Smyth. (2012) Dry Powder Inhaler Device Influence on Carrier Particle Performance. Journal of Pharmaceutical Sciences 101:3, pages 1097-1107.
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Sadaf Matinkhoo, Karlene H. Lynch, Jonathan J. Dennis, Warren H. Finlay & Reinhard Vehring. (2011) Spray-dried Respirable Powders Containing Bacteriophages for the Treatment of Pulmonary Infections. Journal of Pharmaceutical Sciences 100:12, pages 5197-5205.
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Gur Jai Pal Singh & Guirag Poochikian. 2011. Controlled Pulmonary Drug Delivery. Controlled Pulmonary Drug Delivery 489 527 .
Maria H. Bussamra, Rafael Stelmach, Joaquim C. Rodrigues & Alberto Cukier. (2009) A randomized, comparative study of formoterol and terbutaline dry powder inhalers in the treatment of mild to moderate asthma exacerbations in the pediatric acute care setting. Annals of Allergy, Asthma & Immunology 103:3, pages 248-253.
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Christopher J Cates, Matthew J Cates & Toby J Lasserson. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
Carl P. CriéeThomas MeyerWolfgang PetroKnut SommererPeter Zeising. (2006) In Vitro Comparison of Two Delivery Devices for Administering Formoterol: Foradil ® P and Formoterol Ratiopharm Single-Dose Capsule Inhaler . Journal of Aerosol Medicine 19:4, pages 466-472.
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G.K. Crompton, P.J. Barnes, M. Broeders, C. Corrigan, L. Corbetta, R. Dekhuijzen, J.C. Dubus, A. Magnan, F. Massone, J. Sanchis, J.L. Viejo & T. Voshaar. (2006) The need to improve inhalation technique in Europe: A report from the Aerosol Drug Management Improvement Team. Respiratory Medicine 100:9, pages 1479-1494.
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David Pearlman, Henry Milgrom, Denise Till & Barbara Ziehmer. (2006) Effect of formoterol fumarate treatment on exercise-induced bronchoconstriction in children. Annals of Allergy, Asthma & Immunology 97:3, pages 382-388.
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H.-Y. Li, P. C. Seville, I. J. Williamson & J. C. Birchall. (2005) The use of absorption enhancers to enhance the dispersibility of spray-dried powders for pulmonary gene therapy. The Journal of Gene Medicine 7:8, pages 1035-1043.
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Alexander G. ChuchalinAhmed I. ManjraNadezhda N. RozinovaOlga SkopkováGiovanni Della CioppaDenise TillGuenther KaiserTaiwo FasholaJohn Kottakis. (2005) Formoterol Delivered via a New Multi-Dose Dry Powder Inhaler (Certihaler ™ ) Is as Effective and Well Tolerated as the Formoterol Dry Powder Inhaler (Aerolizer ® ) in Children with Persistent Asthma . Journal of Aerosol Medicine 18:1, pages 63-73.
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J. Bousquet, G. Huchon, V. Leclerc, E. Vicaut & G. Lefrançois. (2005) A Randomized, Double-Blind, Double-Dummy, Single-Dose, Efficacy Crossover Trial Comparing Formoterol-HFA (pMDI) versus Formoterol-DPI (Aerolizer<sup>TM</sup>) and Placebo (pMDI or Aerolizer<sup>TM</sup>) in Asthmatic Patients. Respiration 72:1, pages 6-12.
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C. Vogelberg, H.-J. Kremer, B. Ellers-Lenz, M. Engel, J. Maus, F. Conrad & R. Hermann. (2004) Clinical evaluation of the peak inspiratory flow generated by asthmatic children through the Novolizer®. Respiratory Medicine 98:10, pages 924-931.
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