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Current Medical Research and Opinion Volume 20, 2004 - Issue 5
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Research Article

Pioglitazone as monotherapy or in combination with sulfonylurea or metformin enhances insulin sensitivity (HOMA-S or QUICKI) in patients with type 2 diabetes

Dr Meng H. Tan Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN, USACorrespondence[email protected]
,
N. Bradly Glazer Takeda Pharmaceuticals North America, Inc., Lincolnshire, IL, USA
,
Don Johns Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN, USA
,
Mario Widel Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN, USA
&
Kathryn J. Gilmore Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN, USA
Pages 723-728 | Accepted 05 Feb 2004, Published online: 19 Mar 2004

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Bhavik J. Pandya, Morgan Bron, Therese McCall, Andrew P. Yu, Kristina S. Chen, Miles E. Mattson & Eric Q. Wu. (2011) Achieving glycemic goal with initial versus sequential combination therapy using metformin and pioglitazone in type 2 diabetes mellitus. Current Medical Research and Opinion 27:1, pages 189-195.
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Giuseppe Derosa & Sibilla AT Salvadeo. (2009) Risk management in the treatment of type 2 diabetes with pioglitazone. Diabetes, Metabolic Syndrome and Obesity 2, pages 51-60.
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Erland Erdmann, John Dormandy, Robert Wilcox, Massimo Massi-Benedetti & Bernard Charbonnel. (2007) PROactive 07: pioglitazone in the treatment of type 2 diabetes: results of the PROactive study. Vascular Health and Risk Management 3:4, pages 355-370.
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Jochen Seufert. (2006) A fixed-dose combination of pioglitazone and metformin:a promising alternative in metabolic control. Current Medical Research and Opinion 22:sup2, pages S39-S48.
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Andreas Pfützner, Christian A Schneider & Thomas Forst. (2006) Pioglitazone: an antidiabetic drug with cardiovascular therapeutic effects. Expert Review of Cardiovascular Therapy 4:4, pages 445-459.
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Andreas Pfützner & Thomas Forst. (2006) Pioglitazone: an antidiabetic drug with the potency to reduce cardiovascular mortality. Expert Opinion on Pharmacotherapy 7:4, pages 463-476.
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Articles from other publishers (13)

Edoardo Mannucci, Andrea Giaccari, Marco Gallo, Giovanni Targher, Basilio Pintaudi, Riccardo Candido & Matteo Monami. (2022) Effects of pioglitazone on cardiovascular events and all-cause mortality in patients with type 2 diabetes: A meta-analysis of randomized controlled trials. Nutrition, Metabolism and Cardiovascular Diseases 32:3, pages 529-536.
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Pooja Singal, Ranganath Muniyappa, Robin Chisholm, Gail Hall, Hui Chen, Michael J. Quon & Kieren J. Mather. (2010) Simple modeling allows prediction of steady-state glucose disposal rate from early data in hyperinsulinemic glucose clamps. American Journal of Physiology-Endocrinology and Metabolism 298:2, pages E229-E236.
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G. Charpentier & S. Halimi. (2009) Earlier triple therapy with pioglitazone in patients with type 2 diabetes. Diabetes, Obesity and Metabolism 11:9, pages 844-854.
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Kieren Mather. (2009) Surrogate measures of insulin resistance: of rats, mice, and men. American Journal of Physiology-Endocrinology and Metabolism 296:2, pages E398-E399.
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Mark Stolar. (2009) Safety and Efficacy of Pioglitazone/Metformin Combination Therapy in Treatment of Type 2 Diabetes: A Rationale for Earlier Use. Clinical Medicine. Therapeutics 1, pages CMT.S2370.
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P. D. Home & G. Pacini. (2008) Hepatic dysfunction and insulin insensitivity in type 2 diabetes mellitus: a critical target for insulin-sensitizing agents. Diabetes, Obesity and Metabolism 10:9, pages 699-718.
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G. Derosa. (2007) Pioglitazone plus glimepiride: a promising alternative in metabolic control. International Journal of Clinical Practice 61, pages 28-36.
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M. Hanefeld. (2007) Pioglitazone and sulfonylureas: effectively treating type 2 diabetes. International Journal of Clinical Practice 61, pages 20-27.
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Bernd Richter, Elizabeth Bandeira-Echtler, Karla Bergerhoff, Christine Clar & Susanne H Ebrahim. (2006) Pioglitazone for type 2 diabetes mellitus. Cochrane Database of Systematic Reviews 2010:1.
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Marília de Brito Gomes. (2006) Glitazonas e síndrome metabólica: mecanismos de ação, fisiopatologia e indicações terapêuticas. Arquivos Brasileiros de Endocrinologia & Metabologia 50:2, pages 271-280.
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Emma D Deeks & Lesley J Scott. (2006) Pioglitazone/Metformin. Drugs 66:14, pages 1863-1877.
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M. Roden, M. Laakso, D. Johns, M. Widel, R. Urquhart, C. Richardson, S. Mariz & M. H. Tan. (2005) Long-term effects of pioglitazone and metformin on insulin sensitivity in patients with Type 2 diabetes mellitus. Diabetic Medicine 22:8, pages 1101-1106.
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Laura J. Hampson & Loranne Agius. (2005) Increased Potency and Efficacy of Combined Phosphorylase Inactivation and Glucokinase Activation in Control of Hepatocyte Glycogen Metabolism. Diabetes 54:3, pages 617-623.
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