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Research Article

Efficacy of topical ketorolac tromethamine 0.4% for control of pain or discomfort associated with cataract surgery

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Pages 2015-2019 | Accepted 11 Nov 2004, Published online: 03 Dec 2004

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (11)

Eric D Donnenfeld & Ryan D Shojaei. (2019) Effect Of Intracameral Phenylephrine And Ketorolac 1.0%/0.3% On Intraoperative Pain And Opioid Use During Cataract Surgery. Clinical Ophthalmology 13, pages 2143-2150.
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Rahul Reddy & Stephen Jae Kim. (2011) Critical appraisal of ophthalmic ketorolac in treatment of pain and inflammation following cataract surgery. Clinical Ophthalmology 5, pages 751-758.
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Frank A. Bucci$suffix/text()$suffix/text() & L. David Waterbury. (2011) A randomized comparison of to-aqueous penetration of ketorolac 0.45%, bromfenac 0.09% and nepafenac 0.1% in cataract patients undergoing phacoemulsification. Current Medical Research and Opinion 27:12, pages 2235-2239.
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Mayssa Attar, Rhett Schiffman, Lisa Borbridge, Quinn Farnes & Devin Welty. (2010) Ocular pharmacokinetics of 0.45% ketorolac tromethamine. Clinical Ophthalmology 4, pages 1403-1408.
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Eliana B. Souto, Slavomira Doktorovova, Elisabet Gonzalez-Mira, Maria Antonia Egea & Maria Luisa Garcia. (2010) Feasibility of Lipid Nanoparticles for Ocular Delivery of Anti-Inflammatory Drugs. Current Eye Research 35:7, pages 537-552.
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Helga P Sandoval & Kerry D Solomon. (2009) Ketorolac tromethamine 0.4% to relieve eye pain and inflammation following cataract extraction and keratorefractive surgery. Expert Review of Ophthalmology 4:5, pages 461-468.
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Helga P Sandoval, Luis E Fernández de Castro, David T Vroman & Kerry D Solomon. (2007) A review of the use of ketorolac tromethamine 0.4% in the treatment of post-surgical inflammation following cataract and refractive surgery. Clinical Ophthalmology 1:4, pages 367-371.
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L. David Waterbury, David Silliman & Thierry Jolas. (2006) Comparison of cyclooxygenase inhibitory activity and ocular anti-inflammatory effects of ketorolac tromethamine and bromfenac sodium. Current Medical Research and Opinion 22:6, pages 1133-1140.
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Henry D Perry & Eric D Donnenfeld. (2006) An update on the use of ophthalmic ketorolac tromethamine 0.4%. Expert Opinion on Pharmacotherapy 7:1, pages 99-107.
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Articles from other publishers (26)

Shiva Taghe, Shahla Mirzaeei & Masood Bagheri. (2024) Preparation of polycaprolactone and polymethacrylate nanofibers for controlled ocular delivery of ketorolac tromethamine: Pharmacokinetic study in Rabbit's Eye. European Journal of Pharmaceutical Sciences 192, pages 106631.
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Ghobad Mohammadi, Shahla Mirzaeei, Shiva TaghePardis Mohammadi. (2019) Preparation and Evaluation of Eudragit® L100 Nanoparticles LoadedImpregnated with KT Tromethamine Loaded PVA -HEC Insertions forOphthalmic Drug Delivery. Advanced Pharmaceutical Bulletin 9:4, pages 593-600.
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Nathan A. Cleaveland, Derek W. De Mann, Neil E. Carlson & Michael L. Keil. (2017) Efficacy and perioperative timing of bromfenac in the management of ocular discomfort after femtosecond laser–assisted laser in situ keratomileusis. Journal of Cataract and Refractive Surgery 43:2, pages 183-188.
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Yong Koo Kang, Myung Jun Kim, Hong Kyun Kim & Bo Young Chun. (2017) Clinical Analysis of Ocular Parameters Contributing to Intraoperative Pain during Standard Phacoemulsification. Journal of Ophthalmology 2017, pages 1-5.
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Salim Ben Yahia, Rim Kahloun, Nesrine Abroug, Imene Kaibi, Ghassen Laadhari, Bechir Jelliti & Moncef Khairallah. (2016) Comparative effect of topical diclofenac and topical dexamethasone on anterior chamber flare and postoperative pain following rhegmatogenous retinal detachment surgery. International Ophthalmology 36:5, pages 623-628.
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Susanna Porela-Tiihonen, Hannu Kokki, Kai Kaarniranta & Merja Kokki. (2016) Recovery after cataract surgery. Acta Ophthalmologica 94, pages 1-34.
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Afshin ShafieeLyle M. BowmanEddie HouKamran Hosseini. (2013) Aqueous Humor Penetration of Ketorolac Formulated in DuraSite or DuraSite 2 Delivery Systems Compared to Acular LS in Rabbits. Journal of Ocular Pharmacology and Therapeutics 29:9, pages 812-816.
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Constantine D. GeorgakopoulosPanagiotis T. VasilakisOlga E. MakriEleni BeredimaNikolaos M. Pharmakakis. (2012) Effect of Ketorolac 0.5% Drops on Patients' Pain Perception During Intravitreal Injection Procedure. Journal of Ocular Pharmacology and Therapeutics 28:5, pages 455-458.
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Frank A. BucciJr.Jr. & L. David Waterbury. (2011) Prostaglandin E2 Inhibition of Ketorolac 0.45%, Bromfenac 0.09%, and Nepafenac 0.1% in Patients Undergoing Phacoemulsification. Advances in Therapy 28:12, pages 1089-1095.
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Carmen Giannantonio, Patrizia Papacci, Velia Purcaro, Francesco Cota, Mikael Ghennet Tesfagabir, Fernando Molle, Domenico Lepore, Antonio Baldascino & Costantino Romagnoli. (2011) Effectiveness of Ketorolac Tromethamine in Prevention of Severe Retinopathy of Prematurity. Journal of Pediatric Ophthalmology & Strabismus 48:4, pages 247-251.
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Eric D. Donnenfeld, Louis D. Nichamin, David R. Hardten, Michael B. Raizman, William Trattler, Rajesh K. Rajpal, Louis M. Alpern, Carlos Felix, Ronald R. Bradford, Linda Villanueva, David A. Hollander & Rhett M. Schiffman. (2011) Twice-Daily, Preservative-Free Ketorolac 0.45% for Treatment of Inflammation and Pain After Cataract Surgery. American Journal of Ophthalmology 151:3, pages 420-426.e1.
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Stephen J. Kim, Allan J. Flach & Lee M. Jampol. (2010) Nonsteroidal Anti-inflammatory Drugs in Ophthalmology. Survey of Ophthalmology 55:2, pages 108-133.
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Joana Araújo, Elisabet Gonzalez, Maria Antonia Egea, Marisa Luisa Garcia & Eliana B. Souto. (2009) Nanomedicines for ocular NSAIDs: safety on drug delivery. Nanomedicine: Nanotechnology, Biology and Medicine 5:4, pages 394-401.
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Frank A. BucciJr.Jr. & L. David Waterbury. (2009) Aqueous prostaglandin E2 of cataract patients at trough ketorolac and bromfenac levels after 2 days dosing. Advances in Therapy 26:6, pages 645-650.
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Paul J. Dougherty. (2009) Acular LS Before and During LASIK for the Control of Pain: A Randomized, Masked Contralateral Eye Trial. Journal of Refractive Surgery 25:2, pages 210-213.
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Ana Munoz Morales, Muhamet Kivilcim, Muhammad Main, Gholam A. Peyman & Roberta Pereira de Almada Manzano. (2009) Intravitreal Toxicity of Ketorolac Tris Salt and Flurbiprofen. Ophthalmic Surgery, Lasers and Imaging Retina 40:1, pages 38-42.
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W. Andrew MaxwellHarvey J. ReiserRobert H. StewartH. Dwight CavanaghThomas R. WaltersDana P. SagerPatricia A. Meuse. (2008) Nepafenac Dosing Frequency for Ocular Pain and Inflammation Associated with Cataract Surgery. Journal of Ocular Pharmacology and Therapeutics 24:6, pages 593-600.
Crossref
Frank A. Bucci & David L. Waterbury. (2008) Comparison of ketorolac 0.4% and bromfenac 0.09% at trough dosing: Aqueous drug absorption and prostaglandin E2 levels. Journal of Cataract and Refractive Surgery 34:9, pages 1509-1512.
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Hon-Vu Q. Duong, Kenneth C. Westfield & Thomas H.F. Chalkley. (2007) Ketorolac tromethamine LS 0.4% versus nepafenac 0.1% in patients having cataract surgery. Journal of Cataract and Refractive Surgery 33:11, pages 1925-1929.
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Tom Walters, Michael Raizman, Paul Ernest, Johnny Gayton & Robert Lehmann. (2007) In vivo pharmacokinetics and in vitro pharmacodynamics of nepafenac, amfenac, ketorolac, and bromfenac. Journal of Cataract and Refractive Surgery 33:9, pages 1539-1545.
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William Trattler & Marguerite McDonald. (2007) Double-Masked Comparison of Ketorolac Tromethamine 0.4% Versus Nepafenac Sodium 0.1% for Postoperative Healing Rates and Pain Control in Eyes Undergoing Surface Ablation. Cornea 26:6, pages 665-669.
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Joseph Colin. (2007) The Role of NSAIDs in the Management of Postoperative Ophthalmic Inflammation. Drugs 67:9, pages 1291-1308.
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Haluk EsginHasan Semih Samut. (2006) Topical Ketorolac 0.5% for Ocular Pain Relief During Scatter Laser Photocoagulation with 532 nm Green Laser. Journal of Ocular Pharmacology and Therapeutics 22:6, pages 460-464.
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Eric D. Donnenfeld, Henry D. Perry, John R. Wittpenn, Renée Solomon, Alanna Nattis & Timothy Chou. (2006) Preoperative ketorolac tromethamine 0.4% in phacoemulsification outcomes: Pharmacokinetic-response curve. Journal of Cataract and Refractive Surgery 32:9, pages 1474-1482.
Crossref
Helga P. SandovalLuis E. Fernández De CastroDavid T. VromanKerry D. Solomon. (2006) Evaluation of 0.4% Ketorolac Tromethamine Ophthalmic Solution Versus 0.5% Ketorolac Tromethamine Ophthalmic Solution After Phacoemulsification and Intraocular Lens Implantation. Journal of Ocular Pharmacology and Therapeutics 22:4, pages 251-257.
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Barry A. Schechter. (2006) Ketorolac During the Induction Phase of Cyclosporin-A Therapy. Journal of Ocular Pharmacology and Therapeutics 22:2, pages 150-154.
Crossref

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