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Review

Mast cell stabilization and anti-histamine effects of olopatadine ophthalmic solution: a review of pre-clinical and clinical research

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Pages 1377-1387 | Accepted 28 Jun 2005, Published online: 03 Aug 2005

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Ka Wai Kam, Li Jia Chen, Noel Wat & Alvin L. Young. (2017) Topical Olopatadine in the Treatment of Allergic Conjunctivitis: A Systematic Review and Meta-analysis. Ocular Immunology and Inflammation 25:5, pages 668-682.
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Rengin Aslıhan Kurt, Ömür Ucakhan-Gündüz & Kaan Gündüz. (2010) Olopatadine 0.1% and 0.2% ophthalmic solution for the management of ocular allergy. Expert Review of Ophthalmology 5:3, pages 287-296.
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Andrea Leonardi & Luigi Quintieri. (2010) Olopatadine: a drug for allergic conjunctivitis targeting the mast cell. Expert Opinion on Pharmacotherapy 11:6, pages 969-981.
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Andrea Leonardi & Bob Lanier. (2008) Urban eye allergy syndrome: a new clinical entity?. Current Medical Research and Opinion 24:8, pages 2295-2302.
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F. S. Mah, T. O’Brien, T. Kim & G. Torkildsen. (2008) Evaluation of the effects of olopatadine ophthalmic solution, 0.2% on the ocular surface of patients with allergic conjunctivitis and dry eye. Current Medical Research and Opinion 24:2, pages 441-447.
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Andrea Leonardi. (2007) New drug treatments for ocular allergies. Expert Review of Ophthalmology 2:3, pages 397-408.
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William E Berger. (2007) Once-daily olopatadine ophthalmic solution 0.2% in the treatment of allergic conjunctivitis and rhinoconjunctivitis. Expert Review of Pharmacoeconomics & Outcomes Research 7:3, pages 221-226.
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Huei-Jen Kao, Yu-Li Lo, Wen-Jong Vong, Yiu-Jiuan Lin & Hong-Ru Lin. (2006) Treating allergic conjunctivitis using in situ polyelectrolyte gelling systems. Journal of Biomaterials Science, Polymer Edition 17:10, pages 1191-1205.
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Sa-Haeng Kang, Dong-Gu Kim, Dong-Keun Kim, Hyuck-Se Kwon, Na-Young Lee, Hyun-Jeong Oh, Soon-Il Yun & Jong-Sik Jin. (2023) Effects of Thymus quinquecostatus Celakovski on Allergic Responses in OVA-Induced Allergic Rhinitis Mice. Applied Sciences 13:22, pages 12449.
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S Mohan, Santosh Kumar, G Pawan Kumar, Anjali Maheswari, Agrima Bhatia & Anand Sagar. (2023) Assessment of the efficacy of olopatadine 0.1% in the treatment of vernal keratoconjunctivitis in terms of clinical improvement based on total ocular symptom score and ocular surface disease index. Indian Journal of Ophthalmology 71:5, pages 1822-1827.
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Cheng Wang, Yajing Hou, Shuai Ge, Jiayu Lu, Xiangjun Wang, Yuexin Lv, Nan Wang & Huaizhen He. (2022) Synthetic imperatorin derivatives alleviate allergic reactions via mast cells. Biomedicine & Pharmacotherapy 150, pages 112982.
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Maria Malvina Tsamouri, Blythe P. Durbin-Johnson, William T. N. Culp, Carrie A. Palm, Mamta Parikh, Michael S. Kent & Paramita M. Ghosh. (2022) Untargeted Metabolomics Identify a Panel of Urinary Biomarkers for the Diagnosis of Urothelial Carcinoma of the Bladder, as Compared to Urolithiasis with or without Urinary Tract Infection in Dogs. Metabolites 12:3, pages 200.
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Bahareh Hafezi, Lily Chan, Jason P. Knapp, Negar Karimi, Kimia Alizadeh, Yeganeh Mehrani, Byram W. Bridle & Khalil Karimi. (2021) Cytokine Storm Syndrome in SARS-CoV-2 Infections: A Functional Role of Mast Cells. Cells 10:7, pages 1761.
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M. A. Kovalevskaya & L. A. Filina. (2020) Clinical forms of allergic eye manifestations: prospects of therapy. Russian Ophthalmological Journal 13:1, pages 94-101.
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Andrea Leonardi, Diana Silva, Daniel Perez Formigo, Banu Bozkurt, Vibha Sharma, Pia Allegri, Carmen Rondon, Virginia Calder, Dermot Ryan, Marek L. Kowalski, Luis Delgado, Serge Doan & Jean L. Fauquert. (2019) Management of ocular allergy. Allergy 74:9, pages 1611-1630.
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Ketan M. Ranch, Furqan A. Maulvi, Mausam J. Naik, Akshay R. Koli, Rajesh K. Parikh & Dinesh O. Shah. (2019) Optimization of a novel in situ gel for sustained ocular drug delivery using Box-Behnken design: In vitro, ex vivo, in vivo and human studies. International Journal of Pharmaceutics 554, pages 264-275.
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D. Elieh Ali Komi, T. Rambasek & L. Bielory. (2018) Clinical implications of mast cell involvement in allergic conjunctivitis. Allergy 73:3, pages 528-539.
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Jelena Maksić, Ana Stajić, Miroslav Knežević, Bojana Dačić Krnjaja, Biljana Jančić–Stojanović & Mirjana Medenica. (2017) Determination of olopatadine in human tears by hydrophilic interaction liquid chromatography–MS/MS method. Bioanalysis 9:24, pages 1943-1954.
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Marta Łaszcz, Kinga Trzcińska, Anna Witkowska, Agnieszka Ciesielska, Katarzyna Badowska-Rosłonek & Krzysztof Kuziak. (2016) Structural and Physicochemical Studies of Olopatadine Hydrochloride Conformational Polymorphs. Journal of Pharmaceutical Sciences 105:8, pages 2419-2426.
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Ruben Vardanyan & Victor Hruby. 2016. Synthesis of Best-Seller Drugs. Synthesis of Best-Seller Drugs 247 263 .
Soo-Wan Choi, Ju-Hee Ryu, Ji-Sun Park, Myung-Jae Lee, Sung-Vin Yim & Kyung-Tae Lee. (2015) Development and validation for the determination of olopatadine in human plasma by liquid chromatography–tandem mass spectrometry: application to a bioequivalence study of Ilhwa Allotadine tablet (olopatadine HCl 5 mg). Journal of Pharmaceutical Investigation 45:3, pages 285-292.
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L. Munjas Jurkic, M. Buratovic, I. Valentic & D. Stanfel. (2014) UHPLC Study on the Degradation Profiles of Olopatadine Hydrochloride in Eye Drops Subjected to Heat and Filtration Methods of Sterilisation. Chromatographia 77:15-16, pages 1067-1080.
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Hyo Won Jung, Jin Ki Jung & Yong-Ki Park. (2013) Comparison of the efficacy of KOB03, ketotifen, and montelukast in an experimental mouse model of allergic rhinitis. International Immunopharmacology 16:2, pages 254-260.
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N E Leppenen & A N Pampura. (2012) Allergic conjunctivitis in children: from pathogenesis to therapy. Russian Journal of Allergy 9:1, pages 73-78.
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Jin-Ki Jung & Yong-Ki Park. (2012) Effects of Saposhnikoviae Radix on allergic responses in OVA-induced Allergic rhinitis mice. The Korea Journal of Herbology 27:5, pages 85-91.
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Seok-Yong Kang, Seung-Ug Hong & Yong-Ki Park. (2012) Effects of KOB, a polyherbal medicine for allergic rhinitis and its main herb, Astragali Radix on allergic responses in OVA-induced Allergic rhinitis mice. The Korea Journal of Herbology 27:4, pages 1-7.
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Shuang Liu, Agung Endro Nugroho, Masachika Shudou & Kazutaka Maeyama. (2011) Regulation of mucosal mast cell activation by short interfering RNAs targeting syntaxin4. Immunology & Cell Biology 90:3, pages 337-345.
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Oksana Mikhaylovna Kurbacheva & K S Pavlova. (2011) Allergicheskiy kon\"yunktivit:sovremennyy vzglyad na aktual'nuyuproblemu. Russian Journal of Allergy 8:1, pages 82-87.
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Daisuke Kurihara, Nobuyuki Fukuishi, Kazue Kadota, Hirofumi Hamano, Hayato Teruya, Nobuaki Matsui & Masaaki Akagi. (2011) Mast Cells Modulate Interleukin-4 Production Independently of Interferon-gamma Generation by Invariant Natural Killer T Cells through the Suppression of Notch Signaling. JOURNAL OF HEALTH SCIENCE Journal of Health Science 57:2, pages 197-203.
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Alessandro Lambiase, Alessandra Micera & Stefano Bonini. (2009) Multiple action agents and the eye: do they really stabilize mast cells?. Current Opinion in Allergy & Clinical Immunology 9:5, pages 454-465.
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JOHN M. YANNI & NEAL P. BARNEY. 2008. Ocular Therapeutics. Ocular Therapeutics 239 274 .
Steven J. LichtensteinTerry A. PasquineMichael R. EdwardsDavid T. WellsRobert D. GrossStella M. Robertson. (2007) Safety and Tolerability of Olopatadine 0.2% in Children and Adolescents. Journal of Ocular Pharmacology and Therapeutics 23:4, pages 366-371.
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