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Original Article

Extended-release tramadol in the treatment of osteoarthritis:a multicenter, randomized, double-blind, placebo-controlled clinical trial

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Pages 1391-1401 | Accepted 25 May 2006, Published online: 09 Jun 2006

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Read on this site (15)

Wei Li, Hongyi He, Zidan Yang, Ziying Wu & Dongxing Xie. (2022) Comparative risk-benefit profiles of weak opioids in the treatment of osteoarthritis: a network meta-analysis of randomized controlled trials. Postgraduate Medicine 134:8, pages 784-794.
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Joseph V Pergolizzi$suffix/text()$suffix/text(), Robert Taylor$suffix/text()$suffix/text() & Robert B Raffa. (2011) Extended-release formulations of tramadol in the treatment of chronic pain. Expert Opinion on Pharmacotherapy 12:11, pages 1757-1768.
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Robert Zorba Paster. (2010) Chronic pain management issues in the primary care setting and the utility of long-acting opioids. Expert Opinion on Pharmacotherapy 11:11, pages 1823-1833.
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Paul C. Langley, Anuprita D. Patkar, Kimberly A. Boswell, Carmela J. Benson & Jeff R. Schein. (2010) Adverse event profile of tramadol in recent clinical studies of chronic osteoarthritis pain. Current Medical Research and Opinion 26:1, pages 239-251.
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Orlando G Florete, Jim Xiang & Gary J Vorsanger. (2008) Effects of extended-release tramadol on pain-related sleep parameters in patients with osteoarthritis. Expert Opinion on Pharmacotherapy 9:11, pages 1817-1827.
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Jeff R. Schein, Mark R. Kosinski, Carmela Janagap-Benson, Kavita Gajria, Peggy Lin & John D. Freedman. (2008) Functionality and health-status benefits associated with reduction of osteoarthritis pain. Current Medical Research and Opinion 24:5, pages 1255-1265.
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Flaminia Coluzzi & Consalvo Mattia. (2007) Chronic non-cancer pain: Focus on once-daily tramadol formulations. Therapeutics and Clinical Risk Management 3:5, pages 819-829.
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Gérald Mongin. (2007) Tramadol extended-release formulations in the management of pain due to osteoarthritis. Expert Review of Neurotherapeutics 7:12, pages 1775-1784.
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Maria Luz G. Pascual, Rosa Rosanna B. Fleming, Theophilus J. Gana & Gary J. Vorsanger. (2007) Open-label study of the safety and effectiveness of long-term therapy with extended-release tramadol in the management of chronic nonmalignant pain. Current Medical Research and Opinion 23:10, pages 2531-2542.
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Okponanabofa Eradiri, Suryanarayana Sista, John C. K. Lai, Oanh H. Nguyen & Peter H. Silverstone. (2007) Single- and multiple-dose bioequivalence of two once-daily tramadol formulations using stereospecific analysis of tramadol and its demethylated (M1 and M5) metabolites. Current Medical Research and Opinion 23:7, pages 1593-1604.
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Mark Kosinski, Carmela Janagap, Kavita Gajria, Jeff Schein & John Freedman. (2007) Pain relief and pain-related sleep disturbance with extended-release tramadol in patients with osteoarthritis. Current Medical Research and Opinion 23:7, pages 1615-1626.
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Bindu P. Murthy, Donna M. Skee, Alexander P. Danyluk, Vincent Brett, Gary J. Vorsanger & Bruce L. Moskovitz. (2007) Pharmacokinetic model and simulations of dose conversion from immediate- to extended-release tramadol. Current Medical Research and Opinion 23:2, pages 275-284.
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