544
Views
71
CrossRef citations to date
0
Altmetric
Original Article

A multi-centre, randomised, open-label study of atomoxetine compared with standard current therapy in UK children and adolescents with attention-deficit/hyperactivity disorder (ADHD)*

, , , , , & show all
Pages 379-394 | Accepted 07 Dec 2006, Published online: 17 Jan 2007

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (8)

Qiang Liu, Hong Zhang, Qingqing Fang & Lili Qin. (2017) Comparative efficacy and safety of methylphenidate and atomoxetine for attention-deficit hyperactivity disorder in children and adolescents: Meta-analysis based on head-to-head trials. Journal of Clinical and Experimental Neuropsychology 39:9, pages 854-865.
Read now
Keith Saylor, David W. Williams, Kory J. Schuh, Linda Wietecha & Michael Greenbaum. (2010) Effects of atomoxetine on self-reported high-risk behaviors and health-related quality of life in adolescents with ADHD. Current Medical Research and Opinion 26:9, pages 2087-2095.
Read now
Igor Ondrejka, Osman Abali, Ivo Paclt, Magdolna Gácser, Felicia Iftene, Richard Walton, Gavan Harrison, Tamá Treuer & Ferenc Martényi. (2010) A prospective observational study of attention-deficit/hyperactivity disorder in Central and Eastern Europe and Turkey: Symptom severity and treatment options in a paediatric population. International Journal of Psychiatry in Clinical Practice 14:2, pages 116-126.
Read now
Michael Manos, Thomas W. Frazier, Jeanne M. Landgraf, Margaret Weiss & Paul Hodgkins. (2009) HRQL and medication satisfaction in children with ADHD treated with the methylphenidate transdermal system. Current Medical Research and Opinion 25:12, pages 3001-3010.
Read now
Alonso Montoya, Amaia Hervas, Esther Cardo, Josep Artigas, María J. Mardomingo, José A. Alda, Xavier Gastaminza, María J. García-Polavieja, Inmaculada Gilaberte & Rodrigo Escobar. (2009) Evaluation of atomoxetine for first-line treatment of newly diagnosed, treatment-naïve children and adolescents with attention deficit/hyperactivity disorder. Current Medical Research and Opinion 25:11, pages 2745-2754.
Read now
Katharina Manassis. (2007) When attention-deficit/hyperactivity disorder co-occurs with anxiety disorders: effects on treatment. Expert Review of Neurotherapeutics 7:8, pages 981-988.
Read now

Articles from other publishers (63)

Armagan ARAL, Merve ONAT & Mirac Baria USTA. (2023) Factors associated with short-term treatment response of atomoxetine in children and adolescents. Minerva Psychiatry 64:2.
Crossref
Mats Johnson, Carina Gillberg, Ingrid Vinsa, Gunnar Fransson, Lena Samuelsson, Klara Jakobsson, Sven Östlund, Elisabeth Fernell & Christopher Gillberg. (2021) A randomized controlled trial of a new intervention in early symptomatic syndromes eliciting neurodevelopmental clinical examinations: PR-ESSENCE. European Child & Adolescent Psychiatry 32:1, pages 63-74.
Crossref
Michael Huss. 2022. Das Gesundheitswesen und seine volkswirtschaftliche Bedeutung. Das Gesundheitswesen und seine volkswirtschaftliche Bedeutung 161 171 .
蓉 汤. (2021) Research Status of Tic Disorder in Children. Advances in Clinical Medicine 11:03, pages 974-980.
Crossref
Zhi-Sheng Liu, Yong-Hua Cui, Dan Sun, Qing Lu, Yu-Wu Jiang, Li Jiang, Jia-Qin Wang, Rong Luo, Fang Fang, Shui-Zhen Zhou, Yi Wang, Fang-Cheng Cai, Qing Lin, Lan Xiong, Yi Zheng & Jiong Qin. (2020) Current Status, Diagnosis, and Treatment Recommendation for Tic Disorders in China. Frontiers in Psychiatry 11.
Crossref
David R. Coghill, Alain Joseph, Vanja Sikirica, Mark Kosinski, Caleb Bliss & Michael Huss. (2017) Correlations Between Clinical Trial Outcomes Based on Symptoms, Functional Impairments, and Quality of Life in Children and Adolescents With ADHD. Journal of Attention Disorders 23:13, pages 1578-1591.
Crossref
Fahri ÇELEBİ & Dilek ÜNAL. (2019) KLİNİK BİR ÇOCUK-ERGEN ÖRNEKLEMİNDE DEHB İLİŞKİLİ YAŞAM KALİTESİNİN DEĞERLENDİRİLMESİ. Zeynep Kamil Tıp Bülteni 50:2, pages 35-38.
Crossref
Jessica L. Gayleard & Matthew P. Mychailyszyn. (2017) Atomoxetine treatment for children and adolescents with Attention-Deficit/Hyperactivity Disorder (ADHD): a comprehensive meta-analysis of outcomes on parent-rated core symptomatology. ADHD Attention Deficit and Hyperactivity Disorders 9:3, pages 149-160.
Crossref
Masako Nakano, Jennifer Witcher, Yoichi Satoi & Taro Goto. (2016) Pharmacokinetic Profile and Palatability of Atomoxetine Oral Solution in Healthy Japanese Male Adults. Clinical Drug Investigation 36:11, pages 903-911.
Crossref
Nilüfer Demirsoy & Omur Sayligil. (2016) Validity and reliability of a quality-of-life assessment instrument in children aged between 6 and 11 years. Annals of Saudi Medicine 36:4, pages 269-281.
Crossref
Libuše Stárková. (2016) ADHD in the light of contenporary psychiatry and clinical practice. Pediatrie pro praxi 17:1, pages 16-21.
Crossref
Anthony Rostain, Peter S. Jensen, Daniel F. Connor, Laura M. Miesle & Stephen V. Faraone. (2013) Toward Quality Care in ADHD. Journal of Attention Disorders 19:2, pages 99-117.
Crossref
Nicola C. Savill, Jan K. Buitelaar, Ernie Anand, Kathleen Ann Day, Tamás Treuer, Himanshu P. Upadhyaya & David Coghill. (2015) The Efficacy of Atomoxetine for the Treatment of Children and Adolescents with Attention-Deficit/Hyperactivity Disorder: A Comprehensive Review of Over a Decade of Clinical Research. CNS Drugs 29:2, pages 131-151.
Crossref
Ralf W. Dittmann, Tobias Banaschewski, Alexander Schacht & Peter M. Wehmeier. (2014) Findings from the observational COMPLY study in children and adolescents with ADHD: core symptoms, ADHD-related difficulties, and patients’ emotional expression during psychostimulant or nonstimulant ADHD treatment. ADHD Attention Deficit and Hyperactivity Disorders 6:4, pages 291-302.
Crossref
S. Hughes, D. Cohen & R. Jaggi. (2014) Differences in reporting serious adverse events in industry sponsored clinical trial registries and journal articles on antidepressant and antipsychotic drugs: a cross-sectional study. BMJ Open 4:7, pages e005535-e005535.
Crossref
Jasmin Garg, Priti Arun & B. S. Chavan. (2014) Comparative short term efficacy and tolerability of methylphenidate and atomoxetine in attention deficit hyperactivity disorder. Indian Pediatrics 51:7, pages 550-554.
Crossref
Alonso Montoya, Deborah Quail, Ernie Anand, Esther Cardo, José A. Alda & Rodrigo Escobar. (2013) Prognostic factors of improvement in health-related quality of life in atomoxetine-treated children and adolescents with attention-deficit/hyperactivity disorder, based on a pooled analysis. ADHD Attention Deficit and Hyperactivity Disorders 6:1, pages 25-34.
Crossref
Joaquin Fuentes, Marina Danckaerts, Esther Cardo, Kanasagabi Puvanendran, Patrick Berquin, Katrien De Bruyckere, Alonso Montoya, Deborah Quail & Rodrigo Escobar. (2013) Long-Term Quality-of-Life and Functioning Comparison of Atomoxetine Versus Other Standard Treatment in Pediatric Attention-Deficit/Hyperactivity Disorder. Journal of Clinical Psychopharmacology 33:6, pages 766-774.
Crossref
Tobias Banaschewski, César Soutullo, Michel Lecendreux, Mats Johnson, Alessandro Zuddas, Paul Hodgkins, Ben Adeyi, Liza A. Squires & David Coghill. (2013) Health-Related Quality of Life and Functional Outcomes from a Randomized, Controlled Study of Lisdexamfetamine Dimesylate in Children and Adolescents with Attention Deficit Hyperactivity Disorder. CNS Drugs 27:10, pages 829-840.
Crossref
Luigi Mazzone, Valentina Postorino, Laura Reale, Manuela Guarnera, Valeria Mannino, Marco Armando, Laura Fatta, Lavinia De Peppo & Stefano Vicari. (2013) Self-Esteem Evaluation in Children and Adolescents Suffering from ADHD. Clinical Practice & Epidemiology in Mental Health 9:1, pages 96-102.
Crossref
N. N. Zavadenko & N. Yu. Suvorinova. (2013) Attention Deficit Hyperactivity Disorder: Selection of the Optimum Duration of Medical Treatment. Neuroscience and Behavioral Physiology 43:3, pages 346-350.
Crossref
John T. Mitchell & Scott H. Kollins. 2013. Handbook of Adolescent Health Psychology. Handbook of Adolescent Health Psychology 423 445 .
Gregory W. van Wyk, Philip L. Hazell, Michael R. Kohn, Renee E. Granger & Richard J. Walton. (2011) How Oppositionality, Inattention, and Hyperactivity Affect Response to Atomoxetine Versus Methylphenidate. Journal of Attention Disorders 16:4, pages 314-324.
Crossref
Peter M. Wehmeier, Alexander Schacht, Rodrigo Escobar, Amaia Hervas & Ruth Dickson. (2012) Health-related quality of life in ADHD: a pooled analysis of gender differences in five atomoxetine trials. ADHD Attention Deficit and Hyperactivity Disorders 4:1, pages 25-35.
Crossref
Michal Goetz, Chin-Bin Yeh, Igor Ondrejka, Aynur Akay, Ilona Herczeg, Iuliana Dobrescu, Boong Nyun Kim, Xingming Jin, Anne W. Riley, Ferenc Martényi, Gavan Harrison & Tamás Treuer. (2010) A 12-Month Prospective, Observational Study of Treatment Regimen and Quality of Life Associated With ADHD in Central and Eastern Europe and Eastern Asia. Journal of Attention Disorders 16:1, pages 44-59.
Crossref
Raveen Hanwella, Madhri Senanayake & Varuni de Silva. (2011) Comparative efficacy and acceptability of methylphenidate and atomoxetine in treatment of attention deficit hyperactivity disorder in children and adolescents: a meta-analysis. BMC Psychiatry 11:1.
Crossref
Alexander Schacht, Rodrigo Escobar, Thomas Wagner & Peter M. Wehmeier. (2011) Psychometric properties of the quality of life scale Child Health and Illness Profile-Child Edition in a combined analysis of five atomoxetine trials. ADHD Attention Deficit and Hyperactivity Disorders 3:4, pages 335-349.
Crossref
Philip L. Hazell, Michael R. Kohn, Ruth Dickson, Richard J. Walton, Renee E. Granger & Gregory W. van Wyk. (2010) Core ADHD Symptom Improvement With Atomoxetine Versus Methylphenidate. Journal of Attention Disorders 15:8, pages 674-683.
Crossref
David Coghill. (2011) Pragmatic measures in paediatric psychopharmacology — Are we getting it right?. European Neuropsychopharmacology 21:8, pages 571-583.
Crossref
David Coghill. (2011) Escalas y cuestionarios pragmáticos en psicofarmacología pediátrica: ¿estamos haciendo lo correcto?. Psiquiatría Biológica 18:3, pages 105-116.
Crossref
Peter M. Wehmeier, Alexander Schacht, Ralf W. Dittmann, Karin Helsberg, Christian Schneider-Fresenius, Martin Lehmann, Monika Bullinger & Ulrike Ravens-Sieberer. (2010) Effect of atomoxetine on quality of life and family burden: results from a randomized, placebo-controlled, double-blind study in children and adolescents with ADHD and comorbid oppositional defiant or conduct disorder. Quality of Life Research 20:5, pages 691-702.
Crossref
N. N. Zavadenko, N. M. Kolobova & N. Yu. Suvorinova. (2011) Attention Deficit Hyperactivity Disorder and Enuresis in Children and Adolescents. Neuroscience and Behavioral Physiology 41:5, pages 525-531.
Crossref
L. S. Chutko, T. I. Anisimova, S. Yu. Surushkina & K. A. Aitbekov. (2011) Family Problems and Family Therapy in Attention Deficit Hyperactivity Disorder. Neuroscience and Behavioral Physiology 41:4, pages 404-407.
Crossref
Simon Jones, Emma James & Suyash Prasad. (2011) Disease Registries and Outcomes Research in Children. Pediatric Drugs 13:1, pages 33-47.
Crossref
Chris J. BusheNicola Savill. (2011) Atomoxetine in Children and Adolescents with Attention-Deficit/Hyperactivity Disorder. Systematic Review of Review Papers 2009-2011. An Update for Clinicians. Journal of Central Nervous System Disease 3, pages JCNSD.S4391.
Crossref
N. N. Zavadenko, T. V. Lebedeva, O. V. Schasnaya, A. N. Zavadenko, O. M. Zlobina & N. A. Semenova. (2010) Attention Deficit Hyperactivity Syndrome: The Role of Parent and Teacher Questionnaires in Assessing the Social and Psychological Adaptation of Patients. Neuroscience and Behavioral Physiology 41:1, pages 52-56.
Crossref
Peter M Wehmeier, Alexander Schacht, Rodrigo Escobar, Nicola Savill & Val Harpin. (2010) Differences between children and adolescents in treatment response to atomoxetine and the correlation between health-related quality of life and Attention Deficit/Hyperactivity Disorder core symptoms: Meta-analysis of five atomoxetine trials. Child and Adolescent Psychiatry and Mental Health 4:1.
Crossref
David Coghill. (2010) The Impact of Medications on Quality of Life in Attention-Deficit Hyperactivity Disorder. CNS Drugs 24:10, pages 843-866.
Crossref
Thomas W. FrazierMargaret WeissPaul HodgkinsMichael J. ManosJeanne M. LandgrafChristopher Gibbins. (2010) Time Course and Predictors of Health-Related Quality of Life Improvement and Medication Satisfaction in Children Diagnosed with Attention-Deficit/Hyperactivity Disorder Treated with the Methylphenidate Transdermal System. Journal of Child and Adolescent Psychopharmacology 20:5, pages 355-364.
Crossref
Rodrigo Escobar, Alexander Schacht, Peter M. Wehmeier & Thomas Wagner. (2010) Quality of Life and Attention-Deficit/Hyperactivity Disorder Core Symptoms. Journal of Clinical Psychopharmacology 30:2, pages 145-151.
Crossref
Peter M. Wehmeier, Alexander Schacht & Russell A. Barkley. (2010) Social and Emotional Impairment in Children and Adolescents with ADHD and the Impact on Quality of Life. Journal of Adolescent Health 46:3, pages 209-217.
Crossref
Marina Danckaerts, Edmund J. S. Sonuga-Barke, Tobias Banaschewski, Jan Buitelaar, Manfred Döpfner, Chris Hollis, Paramala Santosh, Aribert Rothenberger, Joseph Sergeant, Hans-Christoph Steinhausen, Eric Taylor, Alessandro Zuddas & David Coghill. (2009) The quality of life of children with attention deficit/hyperactivity disorder: a systematic review. European Child & Adolescent Psychiatry 19:2, pages 83-105.
Crossref
Karly P. Garnock-Jones & Gillian M. Keating. (2010) Spotlight on Atomoxetine in Attention-Deficit Hyperactivity Disorder in Children and Adolescents†. CNS Drugs 24:1, pages 85-88.
Crossref
Oscar G Bukstein, L Eugene Arnold, Jeanne M Landgraf & Paul Hodgkins. (2009) Does switching from oral extended-release methylphenidate to the methylphenidate transdermal system affect health-related quality-of-life and medication satisfaction for children with attention-deficit/hyperactivity disorder?. Child and Adolescent Psychiatry and Mental Health 3:1.
Crossref
Ralf W Dittmann, Peter M Wehmeier, Alexander Schacht, Anette Minarzyk, Martin Lehmann, Kathrin Sevecke & Gerd Lehmkuhl. (2009) Atomoxetine treatment and ADHD-related difficulties as assessed by adolescent patients, their parents and physicians. Child and Adolescent Psychiatry and Mental Health 3:1.
Crossref
Michel MaziadeNancie RouleauBobbie LeeAnn RogersLori DavisRuth Dickson. (2009) Atomoxetine and Neuropsychological Function in Children With Attention-Deficit/Hyperactivity Disorder: Results of a Pilot Study. Journal of Child and Adolescent Psychopharmacology 19:6, pages 709-718.
Crossref
Ralf W. Dittmann, Peter M. Wehmeier, Alexander Schacht, Martin Lehmann & Gerd Lehmkuhl. (2009) Self-esteem in adolescent patients with attention-deficit/hyperactivity disorder during open-label atomoxetine treatment: psychometric evaluation of the Rosenberg Self-Esteem Scale and clinical findings. ADHD Attention Deficit and Hyperactivity Disorders 1:2, pages 187-200.
Crossref
Pär Svanborg, Gunilla Thernlund, Per A. Gustafsson, Bruno Hägglöf, Alexander Schacht & Björn Kadesjö. (2009) Atomoxetine improves patient and family coping in attention deficit/hyperactivity disorder: a randomized, double-blind, placebo-controlled study in Swedish children and adolescents. European Child & Adolescent Psychiatry 18:12, pages 725-735.
Crossref
Grazia Dell'Agnello, Dino Maschietto, Carmela Bravaccio, Filippo Calamoneri, Gabriele Masi, Paolo Curatolo, Dante Besana, Francesca Mancini, Andrea Rossi, Lynne Poole, Rodrigo Escobar & Alessandro Zuddas. (2009) Atomoxetine hydrochloride in the treatment of children and adolescents with attention-deficit/hyperactivity disorder and comorbid oppositional defiant disorder: A placebo-controlled Italian study. European Neuropsychopharmacology 19:11, pages 822-834.
Crossref
Ferenc MartényiTamas TreuerSusan Shur-Fen GauSungdo David HongMária PalaczkyJán ŠubaMircea TiberiuPetra UhlíkováTong XuSalih ZoroğluKenneth D. GadowRichard WaltonGavan Harrison. (2009) Attention-Deficit/Hyperactivity Disorder Diagnosis, Co-Morbidities, Treatment Patterns, and Quality of Life in a Pediatric Population in Central and Eastern Europe and Asia. Journal of Child and Adolescent Psychopharmacology 19:4, pages 363-376.
Crossref
S. Prasad, J. Arellano, C. Steer & S. E. Libretto. (2009) Assessing the value of atomoxetine in treating children and adolescents with ADHD in the UK. International Journal of Clinical Practice 63:7, pages 1031-1040.
Crossref
Rodrigo EscobarAlonso MontoyaPepa PolaviejaEsther CardoJosep ArtigasAmaia HervasJoaquín Fuentes. (2009) Evaluation of Patients' and Parents' Quality of Life in a Randomized Placebo-Controlled Atomoxetine Study in Attention-Deficit/Hyperactivity Disorder. Journal of Child and Adolescent Psychopharmacology 19:3, pages 253-263.
Crossref
Karly P. Garnock-Jones & Gillian M. Keating. (2009) Atomoxetine. Pediatric Drugs 11:3, pages 203-226.
Crossref
Gordon Bates. (2018) Drug treatments for attention-deficit hyperactivity disorder in young people. Advances in Psychiatric Treatment 15:3, pages 162-171.
Crossref
David Coghill, Marina Danckaerts, Edmund Sonuga-Barke & Joseph Sergeant. (2009) Practitioner Review: Quality of life in child mental health - conceptual challenges and practical choices. Journal of Child Psychology and Psychiatry 50:5, pages 544-561.
Crossref
Peter M Wehmeier, Alexander Schacht, Ralf W Dittmann & Manfred Döpfner. (2008) Global impression of perceived difficulties in children and adolescents with attention-deficit/hyperactivity disorder: Reliability and validity of a new instrument assessing perceived difficulties from a patient, parent and physician perspective over the day. Child and Adolescent Psychiatry and Mental Health 2:1.
Crossref
Vittorio Mapelli. (2013) Analisi costo-utilità del trattamento con atomoxetina e metilfenidato nei bambini con disturbi da deficit di attenzione con iperattività (ADHD)Cost-utility analysis of treatment of children with attention deficit hyperactivity disorders (ADHD) with atomoxetine and methylphenidate. PharmacoEconomics Italian Research Articles 10:3, pages 151-160.
Crossref
Leo Bastiaens. (2008) Both Atomoxetine and Stimulants Improve Quality of Life in an ADHD Population Treated in a Community Clinic. Psychiatric Quarterly 79:2, pages 133-137.
Crossref
Suyash Prasad & Chris Steer. (2008) Switching from Neurostimulant Therapy to Atomoxetine in Children and Adolescents with Attention-Deficit Hyperactivity Disorder. Pediatric Drugs 10:1, pages 39-47.
Crossref
Nicola O'Connell. (2007) ADHD medication: useful or useless?. Nurse Prescribing 5:11, pages 478-480.
Crossref
Peter M. WehmeierRalf W. DittmannAlexander SchachtAnette MinarzykMartin LehmannKathrin SeveckeGerd Lehmkuhl. (2007) Effectiveness of Atomoxetine and Quality of Life in Children with Attention-Deficit/Hyperactivity Disorder as Perceived by Patients, Parents, and Physicians in an Open-Label Study. Journal of Child and Adolescent Psychopharmacology 17:6, pages 813-830.
Crossref
Saroj Jamdar & Brahan Thara Sathyamoorthy. (2007) Management of attention-deficit/ hyperactivity disorder. British Journal of Hospital Medicine 68:7, pages 360-366.
Crossref
Nicola O'Connell. (2007) Research and development round-up: March 2007. Nurse Prescribing 5:3, pages 130-133.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.