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Original Article

Impact of gender on statin efficacy

, , , , &
Pages 565-574 | Accepted 03 Jan 2007, Published online: 06 Feb 2007

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Read on this site (2)

Peiyuan F. Hsieh, Hsin Tung & Ching-Heng Lin. (2020) Statin effects on post-stroke epilepsy and mortality – Taiwan population-based study. Neurological Research 42:5, pages 422-429.
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Chiara Pavanello & Giuliana Mombelli. (2015) Considering gender in prescribing statins: what do physicians need to know?. Clinical Lipidology 10:6, pages 499-512.
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Articles from other publishers (37)

Rashid Ibdah, Ahmad Alrawashdeh, Sukaina Rawashdeh, Nebras Y. Melhem, Ayman J. Hammoudeh & Mohamad I. Jarrah. (2023) Statin Eligibility according to 2013 ACC/AHA and USPSTF Guidelines among Jordanian Patients with Acute Myocardial Infarction: The Impact of Gender. Cardiovascular Therapeutics 2023, pages 1-7.
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Gianmarco Marcianò, Caterina Palleria, Alessandro Casarella, Vincenzo Rania, Emanuele Basile, Luca Catarisano, Cristina Vocca, Luigi Bianco, Corrado Pelaia, Erika Cione, Bruno D’Agostino, Rita Citraro, Giovambattista De Sarro & Luca Gallelli. (2022) Effect of Statins on Lung Cancer Molecular Pathways: A Possible Therapeutic Role. Pharmaceuticals 15:5, pages 589.
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D. Bizzarri, M.J.T. Reinders, M. Beekman, P.E. Slagboom, BBMRI-NL & E.B. van den Akker. (2022) 1H-NMR metabolomics-based surrogates to impute common clinical risk factors and endpoints. eBioMedicine 75, pages 103764.
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Taylor E. Branyan & Farida Sohrabji. (2020) Sex differences in stroke co-morbidities. Experimental Neurology 332, pages 113384.
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Brice Blum, Leah Wormack, Mason Holtel, Alexandria Penwell, Shyyon Lari, Brittany Walker & Thomas I. Nathaniel. (2019) Gender and thrombolysis therapy in stroke patients with incidence of dyslipidemia. BMC Women's Health 19:1.
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Lorenzo Falsetti, Giovanna Viticchi, Laura Buratti, Clotilde Balucani, Alberto M. Marra & Mauro Silvestrini. (2017) From head to toe: Sex and gender differences in the treatment of ischemic cerebral disease. Pharmacological Research 121, pages 240-250.
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Ilaria Campesi, Flavia Franconi, Giuseppe Seghieri & Marco Meloni. (2017) Sex-gender-related therapeutic approaches for cardiovascular complications associated with diabetes. Pharmacological Research 119, pages 195-207.
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Rory Collins, Christina Reith, Jonathan Emberson, Jane Armitage, Colin Baigent, Lisa Blackwell, Roger Blumenthal, John Danesh, George Davey Smith, David DeMets, Stephen Evans, Malcolm Law, Stephen MacMahon, Seth Martin, Bruce Neal, Neil Poulter, David Preiss, Paul Ridker, Ian Roberts, Anthony Rodgers, Peter Sandercock, Kenneth Schulz, Peter Sever, John Simes, Liam Smeeth, Nicholas Wald, Salim Yusuf & Richard Peto. (2016) Interpretation of the evidence for the efficacy and safety of statin therapy. The Lancet 388:10059, pages 2532-2561.
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Martha Gulati & C. Noel Bairey Merz. (2016) Advances in Lipid Therapy: The Role of Lipid Treatment in Women in Primary Prevention. Progress in Cardiovascular Diseases 59:2, pages 178-189.
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Roda Plakogiannis & Sally A. Arif. (2016) Women Versus Men: Is There Equal Benefit and Safety from Statins?. Current Atherosclerosis Reports 18:2.
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Evan J. Walker, Andrew H. Ko, Elizabeth A. Holly & Paige M. Bracci. (2015) Statin use and risk of pancreatic cancer: Results from a large, clinic-based case-control study. Cancer 121:8, pages 1287-1294.
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. (2015) Efficacy and safety of LDL-lowering therapy among men and women: meta-analysis of individual data from 174 000 participants in 27 randomised trials. The Lancet 385:9976, pages 1397-1405.
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Martha Gulati & C. Noel Bairey Merz. (2015) New cholesterol guidelines and primary prevention in women. Trends in Cardiovascular Medicine 25:2, pages 84-94.
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Mitsuru Shinohara, Naoyuki Sato, Munehisa Shimamura, Hitomi Kurinami, Toshimitsu Hamasaki, Amarnath Chatterjee, Hiromi Rakugi & Ryuichi Morishita. (2014) Possible modification of Alzheimer’s disease by statins in midlife: interactions with genetic and non-genetic risk factors. Frontiers in Aging Neuroscience 6.
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Amos Pines. (2014) Downside of preventive therapies in menopause. Menopause 21:3, pages 207-208.
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Chen-Ying Hung, Yu-Cheng Hsieh, Kuo-Yang Wang, Jin-Long Huang, El-Wui Loh, Ching-Heng Lin & Tsu-Juey Wu. (2013) Efficacy of different statins for primary prevention of atrial fibrillation in male and female patients: A nationwide population-based cohort study. International Journal of Cardiology 168:4, pages 4367-4369.
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Venkata M. Alla, Vrinda Agrawal, Andrew DeNazareth, Syed Mohiuddin, Sudha Ravilla & Marc Rendell. (2013) A Reappraisal of the Risks and Benefits of Treating to Target with Cholesterol Lowering Drugs. Drugs 73:10, pages 1025-1054.
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Rupert A. Payne. (2012) Cardiovascular risk. British Journal of Clinical Pharmacology 74:3, pages 396-410.
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A.S. Peters, C.M. Wieker, M. Hakimi & D. Böckler. (2012) Geschlechtsspezifische Unterschiede in der GefäßchirurgieGender-specific differences in vascular surgery. Gefässchirurgie 17:2, pages 143-157.
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William J. Kostis, Jerry Q. Cheng, Jeanne M. Dobrzynski, Javier Cabrera & John B. Kostis. (2012) Meta-Analysis of Statin Effects in Women Versus Men. Journal of the American College of Cardiology 59:6, pages 572-582.
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Elena V. Kuklina, Nora L. Keenan, William M. Callaghan & Yuling Hong. (2011) Risk of Cardiovascular Mortality in Relation to Optimal Low-Density Lipoprotein Cholesterol Combined with Hypertriglyceridemia: Is There a Difference by Gender?. Annals of Epidemiology 21:11, pages 807-814.
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Niki Katsiki, George Ntaios & Konstantinos Vemmos. (2011) Stroke, obesity and gender: A review of the literature. Maturitas 69:3, pages 239-243.
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Monica Acciarresi, Paola De Rango, Francesca Romana Pezzella, Paola Santalucia, Serena Amici, Maurizio Paciaroni, Valeria Mommi, Giancarlo Agnelli & Valeria Caso. (2011) Secondary Stroke Prevention in Women. Women's Health 7:3, pages 391-397.
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G. Coll De Tuero & A. Rodríguez Poncelas. (2010) Estatinas y diabetes. Hipertensión y Riesgo Vascular 27:6, pages 229-232.
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Radhika N. Bukkapatnam, Nicole B. Gabler & William R. Lewis. (2010) Statins for Primary Prevention of Cardiovascular Mortality in Women: A Systematic Review and Meta-Analysis. Preventive Cardiology 13:2, pages 84-90.
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Poornima BhupathyChristopher Dean HainesLeslie Anne Leinwand. (2010) Influence of Sex Hormones and Phytoestrogens on Heart Disease in Men and Women. Women's Health 6:1, pages 77-95.
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John P. Konhilas. (2010) What We Know and Do Not Know about Sex and Cardiac Disease. Journal of Biomedicine and Biotechnology 2010, pages 1-11.
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Mario Petretta, Pierluigi Costanzo, Pasquale Perrone-Filardi & Massimo Chiariello. (2010) Impact of gender in primary prevention of coronary heart disease with statin therapy: A meta-analysis. International Journal of Cardiology 138:1, pages 25-31.
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Alistair S. HallBeryl M. JacksonAmanda J. FarrinMaria EfthymiouJulian H. BarthJoanne CopelandKristian M. BaileySimon P. R. RomaineAnthony J. BalmforthTerry McCormackAndrew WhiteheadMarcus D. FlatherJane Nixon. (2009) A randomized, controlled trial of simvastatin versus rosuvastatin in patients with acute myocardial infarction: the Secondary Prevention of Acute Coronary Events – Reduction of Cholesterol to Key European Targets Trial. European Journal of Cardiovascular Prevention & Rehabilitation 16:6, pages 712-721.
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A. Kautzky-Willer & A. Handisurya. (2009) Metabolic diseases and associated complications: sex and gender matter!. European Journal of Clinical Investigation 39:8, pages 631-648.
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Hao Yin, Yu Gui & Xi-Long Zheng. (2009) 2-methoxyestradiol inhibits atorvastatin-induced rounding of human vascular smooth muscle cells. Journal of Cellular Physiology, pages n/a-n/a.
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Mathew J Reeves, Cheryl D Bushnell, George Howard, Julia Warner Gargano, Pamela W Duncan, Gwen Lynch, Arya Khatiwoda & Lynda Lisabeth. (2008) Sex differences in stroke: epidemiology, clinical presentation, medical care, and outcomes. The Lancet Neurology 7:10, pages 915-926.
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Zhen Huang, Leif Jansson & Åke Sjöholm. (2008) Gender-specific regulation of pancreatic islet blood flow, insulin levels and glycaemia in spontaneously diabetic Goto–Kakizaki rats. Clinical Science 115:1, pages 35-42.
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Szalat Auryan & Raz Itamar. (2008) Gender-specific care of diabetes mellitus: particular considerations in the management of diabetic women. Diabetes, Obesity and Metabolism 0:0, pages 080520205432340-???.
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John P. KonhilasLeslie A. Leinwand. (2007) The Effects of Biological Sex and Diet on the Development of Heart Failure. Circulation 116:23, pages 2747-2759.
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Akhlaq A. Farooqui, Wei-Yi Ong, Lloyd A. Horrocks, Peng Chen & Tahira Farooqui. (2007) Comparison of biochemical effects of statins and fish oil in brain: The battle of the titans. Brain Research Reviews 56:2, pages 443-471.
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Auryan SzalatItamar Raz. (2016) Gender-Specific Care of Diabetes. Women's Health 3:6, pages 735-764.
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