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Current Medical Research and Opinion Volume 23, 2007 - Issue 3
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Original Article

Cilastatin protection against cyclosporin A-induced nephro­toxicity: clinical evidence

A. Tejedor Department of Nephrology, Laboratory of Renal Physiopathology, Hospital General Universitario Gregorio Marañón, Madrid, SpainCorrespondence[email protected]
,
A. M. Torres Department of Nephrology, Laboratory of Renal Physiopathology, Hospital General Universitario Gregorio Marañón, Madrid, Spain
,
M. Castilla Department of Nephrology, Laboratory of Renal Physiopathology, Hospital General Universitario Gregorio Marañón, Madrid, Spain
,
J. A. Lazaro Department of Nephrology, Laboratory of Renal Physiopathology, Hospital General Universitario Gregorio Marañón, Madrid, Spain
,
C. de Lucas Department of Nephrology, Laboratory of Renal Physiopathology, Hospital General Universitario Gregorio Marañón, Madrid, Spain
&
C. Caramelo Laboratory of Nephrology and Hypertension, Jiménez Díaz Foundation, Madrid, Spain
Pages 505-513 | Accepted 10 Jan 2007, Published online: 29 Jan 2007

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Mersedeh Shayan & Sepideh Elyasi. (2020) Cilastatin as a protective agent against drug-induced nephrotoxicity: a literature review. Expert Opinion on Drug Safety 19:8, pages 999-1010.
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Articles from other publishers (13)

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Ana B. Sanz, Maria Dolores Sanchez-Niño, Adrian M. Ramos & Alberto Ortiz. (2023) Regulated cell death pathways in kidney disease. Nature Reviews Nephrology 19:5, pages 281-299.
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Sawako Goto, Michihiro Hosojima, Hideyuki Kabasawa & Akihiko Saito. (2023) The endocytosis receptor megalin: From bench to bedside. The International Journal of Biochemistry & Cell Biology 157, pages 106393.
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Chun-yan Fang, Da-yong Lou, Li-qin Zhou, Jin-cheng Wang, Bo Yang, Qiao-jun He, Jia-jia Wang & Qin-jie Weng. (2021) Natural products: potential treatments for cisplatin-induced nephrotoxicity. Acta Pharmacologica Sinica 42:12, pages 1951-1969.
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Estefanía Moreno-Gordaliza, Maria Dolores Marazuela, Óscar Pastor, Alberto Lázaro & María Milagros Gómez-Gómez. (2021) Lipidomics Reveals Cisplatin-Induced Renal Lipid Alterations during Acute Kidney Injury and Their Attenuation by Cilastatin. International Journal of Molecular Sciences 22:22, pages 12521.
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Matilde Zaballos, Mercedes Power, María Iluminada Canal-Alonso, María Ángeles González-Nicolás, Wenceslao Vasquez-Jimenez, Pablo Lozano-Lominchar, Pilar Cabrerizo-Torrente, Natividad Palencia-García, Susana Gago-Quiroga, María Dolores Ginel-Feito, Consuelo Jiménez, Alberto Lázaro & Luis González-Bayón. (2021) Effect of Cilastatin on Cisplatin-Induced Nephrotoxicity in Patients Undergoing Hyperthermic Intraperitoneal Chemotherapy. International Journal of Molecular Sciences 22:3, pages 1239.
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Xiaokui Huo, Qiang Meng, Changyuan Wang, Jingjing Wu, Chong Wang, Yanna Zhu, Xiaodong Ma, Huijun Sun & Kexin Liu. (2020) Protective effect of cilastatin against diclofenac‐induced nephrotoxicity through interaction with diclofenac acyl glucuronide via organic anion transporters. British Journal of Pharmacology 177:9, pages 1933-1948.
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Xiaokui Huo, Qiang Meng, Changyuan Wang, Yanna Zhu, Zhihao Liu, Xiaodong Ma, Xiaochi Ma, Jinyong Peng, Huijun Sun & Kexin Liu. (2019) Cilastatin protects against imipenem-induced nephrotoxicity via inhibition of renal organic anion transporters (OATs). Acta Pharmaceutica Sinica B 9:5, pages 986-996.
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Estefanía Moreno-Gordaliza, Diego Esteban-Fernández, Alberto Lázaro, Sarah Aboulmagd, Blanca Humanes, Alberto Tejedor, Michael W. Linscheid & M. Milagros Gómez-Gómez. (2018) Lipid imaging for visualizing cilastatin amelioration of cisplatin-induced nephrotoxicity. Journal of Lipid Research 59:9, pages 1561-1574.
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Blanca Humanes, Sonia Camaño, Jose Manuel Lara, Venkatta Sabbisetti, María Ángeles González-Nicolás, Joseph V. Bonventre, Alberto Tejedor & Alberto Lázaro. (2017) Cisplatin-induced renal inflammation is ameliorated by cilastatin nephroprotection. Nephrology Dialysis Transplantation 32:10, pages 1645-1655.
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Blanca Humanes, Juan Carlos Jado, Sonia Camaño, Virginia López-Parra, Ana María Torres, Luís Antonio Álvarez-Sala, Emilia Cercenado, Alberto Tejedor & Alberto Lázaro. (2015) Protective Effects of Cilastatin against Vancomycin-Induced Nephrotoxicity. BioMed Research International 2015, pages 1-12.
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Sonia Camano, Alberto Lazaro, Estefania Moreno-Gordaliza, Ana M. Torres, Carmen de Lucas, Blanca Humanes, Jose A. Lazaro, M. Milagros Gomez-Gomez, Lisardo Bosca & Alberto Tejedor. (2010) Cilastatin Attenuates Cisplatin-Induced Proximal Tubular Cell Damage. Journal of Pharmacology and Experimental Therapeutics 334:2, pages 419-429.
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Emmanuel A. Burdmann & William M. Bennett. 2008. Clinical Nephrotoxins. Clinical Nephrotoxins 617 682 .

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