Advanced search
Publication Cover
Current Medical Research and Opinion Volume 23, 2007 - Issue 5
Submit an article Journal homepage
555
Views
21
CrossRef citations to date
0
Altmetric
Original Article

Randomized, double-blind, placebo-controlled clinical trial of loperamide plus simethicone versus loperamide alone and simethicone alone in the treatment of acute diarrhea with gas-related abdominal discomfort

Stephen B. Hanauer University of Chicago, Chicago, IL, USACorrespondence[email protected]
,
Herbert L. DuPont St. Luke's Episcopal Hospital, University of Texas–Houston School of Public Health, and Baylor College of Medicine, Houston, TX, USA
,
Kimberly M. Cooper McNeil Consumer Healthcare, Fort Washington, PA, USA
&
Charles Laudadio McNeil Consumer Healthcare, Fort Washington, PA, USA
Pages 1033-1043 | Accepted 20 Feb 2007, Published online: 26 Mar 2007

Citations (21)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Mariana Hollanda Martins Da Rocha, André Dong Won Lee, Marcia Lucia De Mario Marin, Salomao Faintuch, Asher Mishaly & Joel Faintuch. (2020) Treating short bowel syndrome with pharmacotherapy. Expert Opinion on Pharmacotherapy 21:6, pages 709-720.
Read now

Articles from other publishers (20)

Daniel Zakowiecki, Margarethe Richter, Ceren Yuece, Annika Voelp, Maximilian Ries, Markos Papaioannou, Peter Edinger, Tobias Hess, Krystyna Mojsiewicz-Pieńkowska & Krzysztof Cal. (2023) Towards the Continuous Manufacturing of Liquisolid Tablets Containing Simethicone and Loperamide Hydrochloride with the Use of a Twin-Screw Granulator. Pharmaceutics 15:4, pages 1265.
Crossref
. 2022. Arzneimitteltherapie in der Palliativmedizin. Arzneimitteltherapie in der Palliativmedizin 109 180 .
Judy Nee & Anthony Lembo. (2021) Review Article: Current and future treatment approaches for IBS with diarrhoea (IBS‐D) and IBS mixed pattern (IBS‐M). Alimentary Pharmacology & Therapeutics 54:S1.
Crossref
Asma Fikree & Peter Byrne. (2021) Management of functional gastrointestinal disorders. Clinical Medicine 21:1, pages 44-52.
Crossref
Daniel L. KrinskyJennifer Robinson & Traci M. Poole. 2020. Handbook of Nonprescription Drugs: An Interactive Approach to Self-Care, 20th Edition. Handbook of Nonprescription Drugs: An Interactive Approach to Self-Care, 20th Edition.
Max J. Schmulson, Jazmin Chiu-Ugalde, Adolfo Sáez-Ríos, Aurelio López-Colombo, Gualberto J. Mateos-Pérez, José María Remes-Troche, Sergio Sobrino-Cossio, Julio C. Soto-Pérez, José L. Tamayo de la Cuesta, Oscar T. Teramoto-Matsubara & Juan C. López-Alvarenga. (2020) Efficacy of the Combination of Pinaverium Bromide 100 mg Plus Simethicone 300 mg in Abdominal Pain and Bloating in Irritable Bowel Syndrome: A Randomized, Placebo-controlled Trial. Journal of Clinical Gastroenterology 54:4, pages e30-e39.
Crossref
Nikolay Bugaev, Bishwajit Bhattacharya, William C. Chiu, John J. Como, Michael W. Cripps, Paula Ferrada, Rondi B. Gelbard, Stephen Gondek, George Kasotakis, Dennis Kim, Caleb Mentzer, Bryce R. H. Robinson, Edgardo S. Salcedo & D. Dante Yeh. (2019) Antimotility agents for the treatment of acute noninfectious diarrhea in critically ill patients: A practice management guideline from the Eastern Association for the Surgery of Trauma. Journal of Trauma and Acute Care Surgery 87:4, pages 915-921.
Crossref
David J. Cangemi & Brian E. Lacy. (2019) Management of irritable bowel syndrome with diarrhea: a review of nonpharmacological and pharmacological interventions. Therapeutic Advances in Gastroenterology 12, pages 175628481987895.
Crossref
. 2018. Arzneimitteltherapie in der Palliativmedizin. Arzneimitteltherapie in der Palliativmedizin 83 143 .
Daniel L. Krinsky, Stefanie P. Ferreri, Brian Hemstreet, Anne L. Hume, Gail D. Newton, Carol J. Rollins & Karen J. TietzeJennifer Robinson. 2017. Handbook of Nonprescription Drugs: An Interactive Approach to Self-Care, 19th Edition. Handbook of Nonprescription Drugs: An Interactive Approach to Self-Care, 19th Edition.
Nasrin Fazel, Akbar Pejhan, Mohsen Taghizadeh, Yaser Tabarraei & Nasrin Sharifi. (2017) Effects of Anethum graveolens L. (Dill) essential oil on the intensity of retained intestinal gas, flatulence and pain after cesarean section: A randomized, double-blind placebo-controlled trial. Journal of Herbal Medicine 8, pages 8-13.
Crossref
Bobby Desai & Alpa Desai. 2017. Primary Care for Emergency Physicians. Primary Care for Emergency Physicians 187 205 .
Elizabeth Barba, Anna Accarino, Alfredo Soldevilla, Juan-R Malagelada & Fernando Azpiroz. (2016) Randomized, Placebo-Controlled Trial of Biofeedback for the Treatment of Rumination. American Journal of Gastroenterology 111:7, pages 1007-1013.
Crossref
Mark S Riddle, Herbert L DuPont & Bradley A Connor. (2016) ACG Clinical Guideline: Diagnosis, Treatment, and Prevention of Acute Diarrheal Infections in Adults. American Journal of Gastroenterology 111:5, pages 602-622.
Crossref
Jeremy Cottrell, Kerstin Koenig, Roland Perfekt & Robert Hofmann. (2015) Comparison of Two Forms of Loperamide–Simeticone and a Probiotic Yeast (Saccharomyces boulardii) in the Treatment of Acute Diarrhoea in Adults: A Randomised Non-Inferiority Clinical Trial. Drugs in R&D 15:4, pages 363-373.
Crossref
Alexandra Partenhauser, Flavia Laffleur, Julia Rohrer & Andreas Bernkop-Schnürch. (2015) Thiolated silicone oil: Synthesis, gelling and mucoadhesive properties. Acta Biomaterialia 16, pages 169-177.
Crossref
Jennifer Robinson. 2015. Handbook of Nonprescription Drugs: An Interactive Approach to Self-Care, 18th Edition. Handbook of Nonprescription Drugs: An Interactive Approach to Self-Care, 18th Edition.
. 2015. Arzneimitteltherapie in der Palliativmedizin. Arzneimitteltherapie in der Palliativmedizin 65 126 .
James R. Neale, Shirley James, James Callaghan & Praful Patel. (2013) Premedication with N-acetylcysteine and simethicone improves mucosal visualization during gastroscopy. European Journal of Gastroenterology & Hepatology 25:7, pages 778-783.
Crossref
Claud Regnard, Robert Twycross, Mary Mihalyo & Andrew Wilcock. (2011) Loperamide. Journal of Pain and Symptom Management 42:2, pages 319-323.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.