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Original Article

Zonisamide and renal calculi in patients with epilepsy: how big an issue?

Pages 1765-1773 | Accepted 04 Jun 2007, Published online: 25 Jun 2007

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (8)

Slobodan M. Janković. (2020) Evaluation of zonisamide for the treatment of focal epilepsy: a review of pharmacokinetics, clinical efficacy and adverse effects. Expert Opinion on Drug Metabolism & Toxicology 16:3, pages 169-177.
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Alberto Verrotti, Renato Tambucci, Ludovica Di Francesco, Piero Pavone, Giulia Iapadre, Emma Altobelli, Sara Matricardi, Giovanni Farello & Vincenzo Belcastro. (2020) The role of polytherapy in the management of epilepsy: suggestions for rational antiepileptic drug selection. Expert Review of Neurotherapeutics 20:2, pages 167-173.
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Arne Reimers & Hanna Ljung. (2019) An evaluation of zonisamide, including its long-term efficacy, for the treatment of focal epilepsy. Expert Opinion on Pharmacotherapy 20:8, pages 909-915.
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Sherifa A. Hamed, Tarek A. Rageh, Amany O. Mohamad & Suzan M. Abou Elnour. (2018) Renal dysfunctions/injury in adult epilepsy patients treated with carbamazepine or valproate. Expert Review of Clinical Pharmacology 11:8, pages 819-824.
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Sherifa Ahmed Hamed. (2017) The effect of antiepileptic drugs on the kidney function and structure. Expert Review of Clinical Pharmacology 10:9, pages 993-1006.
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Gaetano Zaccara, Luciana Tramacere & Massimo Cincotta. (2011) Drug safety evaluation of zonisamide for the treatment of epilepsy. Expert Opinion on Drug Safety 10:4, pages 623-631.
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Gaetano Zaccara & Luigi M Specchio. (2009) Long-term safety and effectiveness of zonisamide in the treatment of epilepsy: a review of the literature. Neuropsychiatric Disease and Treatment 5, pages 249-259.
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Sanjeev V Kothare & Joseph Kaleyias. (2008) Zonisamide: review of pharmacology, clinical efficacy, tolerability, and safety. Expert Opinion on Drug Metabolism & Toxicology 4:4, pages 493-506.
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Articles from other publishers (33)

Tafere Mulaw Belete. (2023) Recent Progress in the Development of New Antiepileptic Drugs with Novel Targets. Annals of Neurosciences 30:4, pages 262-276.
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Carla LoPinto-Khoury. (2022) Long-Term Effects of Antiseizure Medications. Seminars in Neurology 42:05, pages 583-593.
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Rushelle Byfield & Lawrence Copelovitch. 2022. Diagnosis and Management of Pediatric Nephrolithiasis. Diagnosis and Management of Pediatric Nephrolithiasis 65 75 .
Alberto Verrotti, Simona Lattanzi, Francesco Brigo & Gaetano Zaccara. (2020) Pharmacodynamic interactions of antiepileptic drugs: From bench to clinical practice. Epilepsy & Behavior 104, pages 106939.
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Linda J. Stephen & Martin J. Brodie. (2020) Pharmacological Management of the Genetic Generalised Epilepsies in Adolescents and Adults. CNS Drugs 34:2, pages 147-161.
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Maria Chiara Sighinolfi, Ahmed Eissa, Luigi Bevilacqua, Ahmed Zoeir, Silvia Ciarlariello, Elena Morini, Stefano Puliatti, Viviana Durante, Pier Luca Ceccarelli, Salvatore Micali, Giampaolo Bianchi & Bernardo Rocco. (2019) Drug-Induced Urolithiasis in Pediatric Patients. Pediatric Drugs 21:5, pages 323-344.
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. (2018) Be aware of the risk of drug-induced kidney stones and take appropriate steps to prevent or treat their occurrence. Drugs & Therapy Perspectives 35:2, pages 64-70.
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Mark A. Perazella. (2018) Pharmacology behind Common Drug Nephrotoxicities. Clinical Journal of the American Society of Nephrology 13:12, pages 1897-1908.
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Michel Daudon, Vincent Frochot, Dominique Bazin & Paul Jungers. (2017) Drug-Induced Kidney Stones and Crystalline Nephropathy: Pathophysiology, Prevention and Treatment. Drugs 78:2, pages 163-201.
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Adam D. Simmons. 2018. Integrative Medicine. Integrative Medicine 143 151.e3 .
Martin J Brodie. (2017) Tolerability and Safety of Commonly Used Antiepileptic Drugs in Adolescents and Adults: A Clinician’s Overview. CNS Drugs 31:2, pages 135-147.
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. 2016. Meyler's Side Effects of Drugs. Meyler's Side Effects of Drugs 597 660 .
Elizabeth Harvey & Walid A. Farhat. 2016. Pediatric Kidney Disease. Pediatric Kidney Disease 1135 1191 .
. 2015. The Treatment of Epilepsy. The Treatment of Epilepsy 680 688 .
Yasmin Idu Jion, Amanda Raff, Brian M. Grosberg & Randolph W. Evans. (2015) The Risk and Management of Kidney Stones From the Use of Topiramate and Zonisamide in Migraine and Idiopathic Intracranial Hypertension. Headache: The Journal of Head and Face Pain 55:1, pages 161-166.
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Uma Menon & Ilo E. Leppik. 2015. Seizures in Cerebrovascular Disorders. Seizures in Cerebrovascular Disorders 121 132 .
J. Helen Cross, Stéphane Auvin, Anna Patten & Luigi Giorgi. (2014) Safety and tolerability of zonisamide in paediatric patients with epilepsy. European Journal of Paediatric Neurology 18:6, pages 747-758.
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Michel Daudon & Paul Jungers. 2014. Urinary Stones. Urinary Stones 106 119 .
Sheridan M. Hoy. (2013) Zonisamide: A Review of Its Use in the Management of Adults with Partial Seizures. Drugs 73:12, pages 1321-1338.
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Athanasios Gaitatzis & Josemir W. Sander. (2013) The Long-Term Safety of Antiepileptic Drugs. CNS Drugs 27:6, pages 435-455.
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Adam D. Simmons. 2012. Integrative Medicine. Integrative Medicine 122 130.e2 .
Jose de Leon. 2012. A Practitioner's Guide to Prescribing Antiepileptics and Mood Stabilizers for Adults with Intellectual Disabilities. A Practitioner's Guide to Prescribing Antiepileptics and Mood Stabilizers for Adults with Intellectual Disabilities 461 479 .
Jose de Leon. 2012. A Practitioner's Guide to Prescribing Antiepileptics and Mood Stabilizers for Adults with Intellectual Disabilities. A Practitioner's Guide to Prescribing Antiepileptics and Mood Stabilizers for Adults with Intellectual Disabilities 395 418 .
M.L. Miller, S.A. Center, J.F. Randolph, M.L. Lepherd, M.A. Cautela & C.W. Dewey. (2011) Apparent Acute Idiosyncratic Hepatic Necrosis Associated with Zonisamide Administration in a Dog. Journal of Veterinary Internal Medicine 25:5, pages 1156-1160.
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Yuriko Tanaka, Yoshiko Abe, Yuji Oto, Hisashi Itabashi, Nobuyuki Murakami, Ryouichi Sakuta & Toshiro Nagai. (2011) Five cases of West syndrome complicated by nephrocalcinosis during combination therapy with ACTH and zonisamide. Nihon Shoni Jinzobyo Gakkai Zasshi 24:1, pages 86-91.
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Elahna Paul, Kerry D. Conant, Irie E. Dunne, Heidi H. Pfeifer, David A. Lyczkowski, Michael A. Linshaw & Elizabeth A. Thiele. (2010) Urolithiasis on the ketogenic diet with concurrent topiramate or zonisamide therapy. Epilepsy Research 90:1-2, pages 151-156.
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Ilo E. Leppik & Angela K. Birnbaum. (2010) Epilepsy in the elderly. Annals of the New York Academy of Sciences 1184:1, pages 208-224.
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Gaetano Zaccara. 2010. Side Effects of Drugs Annual 32 - A worldwide yearly survey of new data and trends in adverse drug reactions and interactions. Side Effects of Drugs Annual 32 - A worldwide yearly survey of new data and trends in adverse drug reactions and interactions 123 182 .
Michel Daudon & Paul Jungers. 2011. Urinary Tract Stone Disease. Urinary Tract Stone Disease 225 237 .
Mark A. Perazella. (2009) Renal Vulnerability to Drug Toxicity. Clinical Journal of the American Society of Nephrology 4:7, pages 1275-1283.
Crossref
Pedro Emilio Bermejo & Rodolfo Dorado. (2009) Zonisamide for Migraine Prophylaxis in Patients Refractory to Topiramate. Clinical Neuropharmacology 32:2, pages 103-106.
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Nicholas M Wallingford, Puspha Sinnayah, Frank P Bymaster, Kishore M Gadde, Ranga K Krishnan, Anthony A McKinney, Ronald P Landbloom, Gary D Tollefson & Michael A Cowley. (2008) Zonisamide Prevents Olanzapine-Associated Hyperphagia, Weight Gain, and Elevated Blood Glucose in Rats. Neuropsychopharmacology 33:12, pages 2922-2933.
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S. J. Wroe, A. B. Yeates & A. Marshall. (2008) Long-term safety and efficacy of zonisamide in patients with refractory partial-onset epilepsy. Acta Neurologica Scandinavica 118:2, pages 87-93.
Crossref

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