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Review

A comparative review of the efficacy and safety of established phosphate binders: calcium, sevelamer, and lanthanum carbonate*

Pages 3167-3175 | Accepted 01 Oct 2007, Published online: 07 Nov 2007

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Read on this site (7)

Valeria Cernaro, Sebastiano Calimeri, Alfredo Laudani & Domenico Santoro. (2020) Clinical Evaluation of the Safety, Efficacy and Tolerability of Lanthanum Carbonate in the Management of Hyperphosphatemia in Patients with End-Stage Renal Disease. Therapeutics and Clinical Risk Management 16, pages 871-880.
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Jinshyun Ruth Wu-Wong & Masahide Mizobuchi. (2014) Is there a need for new phosphate binders to treat phosphate imbalance associated with chronic kidney disease?. Expert Opinion on Investigational Drugs 23:11, pages 1465-1475.
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Takashi Shigematsu, Yuri Nakashima, Masaki Ohya, Koichi Tatsuta, Daisuke Koreeda, Wataru Yoshimoto, Shintaro Yamanaka, Toshifumi Sakaguchi, Yoshiyuki Hanba, Toru Mima & Shigeo Negi. (2012) The management of hyperphosphatemia by lanthanum carbonate in chronic kidney disease patients. International Journal of Nephrology and Renovascular Disease 5, pages 81-89.
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Stephen J.P. Damment. (2011) Pharmacology of the Phosphate Binder, Lanthanum Carbonate. Renal Failure 33:2, pages 217-224.
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Patrick Biggar & Markus Ketteler. (2010) Sevelamer carbonate for the treatment of hyperphosphatemia in patients with kidney failure (CKD III – V). Expert Opinion on Pharmacotherapy 11:16, pages 2739-2750.
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Veerle P Persy, Geert J Behets, Marc E De Broe & Patrick C D’Haese. (2009) Management of hyperphosphatemia in patients with end-stage renal disease: focus on lanthanum carbonate. International Journal of Nephrology and Renovascular Disease 2, pages 1-8.
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Hsiao-Tien Chen, Kuo-Chuan Hung, Chin-Wei Hsu, Jui-Yi Chen, Chien-Cheng Liu, I-Wen Chen & Cheuk-Kwan Sun. (2023) The efficacy and safety of cuttlebone for lowering serum phosphate in patients with end-stage renal disease: a meta-analysis of randomized controlled trials. Frontiers in Pharmacology 14.
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Qimeng Zhang, Mingzheng Wang, Guangqin Mu, Haotian Ren, Congshuang He, Qian Xie, Quanxiao Liu, Jigang Wang & Ruitao Cha. (2021) Adsorptivity of cationic cellulose nanocrystals for phosphate and its application in hyperphosphatemia therapy. Carbohydrate Polymers 255, pages 117335.
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Annabel Biruete, Kathleen M. Hill Gallant, Stephen R. Lindemann, Gretchen N. Wiese, Neal X. Chen & Sharon M. Moe. (2020) Phosphate Binders and Nonphosphate Effects in the Gastrointestinal Tract. Journal of Renal Nutrition 30:1, pages 4-10.
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Fellipe A. T. de Figueiredo, Roberta C. Shimano, Edilson Ervolino, Dimitrius L. Pitol, Raquel F. Gerlach & Joao Paulo M. Issa. (2019) Doxycycline reduces osteopenia in female rats. Scientific Reports 9:1.
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Ezequiel Bellorin-Font, George Vasquez-Rios & Kevin J. Martin. (2019) Controversies in the Management of Secondary Hyperparathyroidism in Chronic Kidney Disease. Current Osteoporosis Reports 17:5, pages 333-342.
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Fellype Carvalho Barreto, Daniela Veit Barreto, Ziad A. Massy & Tilman B. Drüeke. (2019) Strategies for Phosphate Control in Patients With CKD. Kidney International Reports 4:8, pages 1043-1056.
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Kamyar Kalantar-Zadeh, Vidhya Parameswaran, Linda H. Ficociello, Ludmila Anderson, Norma J. Ofsthun, Christopher Kwoh, Claudy Mullon, Robert J. Kossmann & Daniel W. Coyne. (2018) Real-World Scenario Improvements in Serum Phosphorus Levels and Pill Burden in Peritoneal Dialysis Patients Treated with Sucroferric Oxyhydroxide. American Journal of Nephrology 47:3, pages 153-161.
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Alastair J Hutchison, Rosamund J Wilson, Svetlana Garafola & John Brian Copley. (2016) Lanthanum carbonate: safety data after 10 years. Nephrology 21:12, pages 987-994.
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Lisa Gutekunst. (2016) An Update on Phosphate Binders: A Dietitian's Perspective. Journal of Renal Nutrition 26:4, pages 209-218.
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Jorge B. Cannata-Andía & Kevin J. Martin. (2016) The challenge of controlling phosphorus in chronic kidney disease. Nephrology Dialysis Transplantation 31:4, pages 541-547.
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Yongsheng Yang, Adil Mohammad, Robert T. Berendt, Alan Carlin, Mansoor A. Khan & Patrick J. Faustino. (2016) Evaluation of the In Vitro Efficacy of Sevelamer Hydrochloride and Sevelamer Carbonate. Journal of Pharmaceutical Sciences 105:2, pages 864-875.
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Blanca Gros, Antonio Galán, Emilio González-Parra, Jose A Herrero, Maria Echave, Stefan Vegter, Keith Tolley & Itziar Oyagüez. (2015) Cost effectiveness of lanthanum carbonate in chronic kidney disease patients in Spain before and during dialysis. Health Economics Review 5:1.
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Florian S. Gutzwiller, Alena M. Pfeil, Zanfina Ademi, Patricia R. Blank, Peter G. Braunhofer, Thomas D. Szucs & Matthias Schwenkglenks. (2015) Cost Effectiveness of Sucroferric Oxyhydroxide Compared with Sevelamer Carbonate in the Treatment of Hyperphosphataemia in Patients Receiving Dialysis, from the Perspective of the National Health Service in Scotland. PharmacoEconomics 33:12, pages 1311-1324.
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Fateme Shamekhi Amiri. (2015) Contemporary management of phosphorus retention in chronic kidney disease: a review. Clinical and Experimental Nephrology 19:6, pages 985-999.
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Z. Asemi, P. Saneei, S.-S. Sabihi, A. Feizi & A. Esmaillzadeh. (2015) Total, dietary, and supplemental calcium intake and mortality from all-causes, cardiovascular disease, and cancer: A meta-analysis of observational studies. Nutrition, Metabolism and Cardiovascular Diseases 25:7, pages 623-634.
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Elizabeth A. Bobeck, Erica M. Hellestad, Jordan M. Sand, Michelle L. Piccione, Jeff W. Bishop, Christian Helvig, Martin Petkovich & Mark E. Cook. (2015) Oral peptide specific egg antibody to intestinal sodium-dependent phosphate co-transporter-2b is effective at altering phosphate transport in vitro and in vivo. Poultry Science 94:6, pages 1128-1137.
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T.M.-H. Nguyen, R.H. Müller, M. Taupitz, J. Schnorr, B. Hamm & S. Wagner. (2015) Novel oral phosphate binder with nanocrystalline maghemite-phosphate binding capacity and pH effect. International Journal of Pharmaceutics 482:1-2, pages 21-26.
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Caroline M. Perry & Greg L. Plosker. (2014) Sevelamer Carbonate: A Review in Hyperphosphataemia in Adults with Chronic Kidney Disease. Drugs 74:7, pages 771-792.
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Xiaojian Jiang, Yongsheng Yang & Ethan Stier. 2014. FDA Bioequivalence Standards. FDA Bioequivalence Standards 297 334 .
Jing Xu, Yi-Xiang Zhang, Xue-Qing Yu, Zhi-Hong Liu, Li-Ning Wang, Jiang-Hua Chen, Ya-Ping Fan, Zhao-Hui Ni, Mei Wang, Fa-Huan Yuan, Guo-Hua Ding, Xiang-Mei Chen, Ai-Ping Zhang & Chang-Lin Mei. (2013) Lanthanum carbonate for the treatment of hyperphosphatemia in CKD 5D: multicenter, double blind, randomized, controlled trial in mainland China. BMC Nephrology 14:1.
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Zaw Thet, Aung Ko WIN, Eugenie Pedagogos, Jennifer Beavis, Sandra Crikis & Craig Nelson. (2013) Differential effects of phosphate binders on pre-dialysis serum bicarbonate in end-stage kidney disease patients on maintenance haemodialysis. BMC Nephrology 14:1.
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Adrian Covic & Anjay Rastogi. (2013) Hyperphosphatemia in patients with ESRD: assessing the current evidence linking outcomes with treatment adherence. BMC Nephrology 14:1.
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Tsutomu Sakurada, Daisuke Oishi, Yugo Shibagaki, Takashi Yasuda & Kenjiro Kimura. (2013) Efficacy of oral powder compared with chewable tablets for lanthanum carbonate administration in hemodialysis patients. Hemodialysis International 17, pages S2-S6.
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Junko Nakaki, Shinichi Yamaguchi, Yuichi Torii, Atsushi Inoue, Satoshi Minakami, Takami Kanno, Masanori Murakami, Masahiro Tsuzuki, Hidenori Mochizuki, Kazuharu Suyama & Mitsuko Miyamoto. (2013) Effect of fatty acids on the phosphate binding of TRK-390, a novel, highly selective phosphate-binding polymer. European Journal of Pharmacology 714:1-3, pages 312-317.
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Michiya Ohno, Hiroshige Ohashi, Hiroshi Oda, Haruko Yokoyama, Miho Okada, Mayu Nagaya, Kumiko Izumi, Hitomi Ito & Shuji Katoh. (2013) Lanthanum Carbonate for Hyperphosphatemia in Patients on Peritoneal Dialysis. Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis 33:3, pages 297-303.
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Yongsheng Yang, Srikant Bykadi, Alan S. Carlin, Rakhi B. Shah, Lawrence X. Yu & Mansoor A. khan. (2013) Comparative Evaluation of the In Vitro Efficacy of Lanthanum Carbonate Chewable Tablets. Journal of Pharmaceutical Sciences 102:4, pages 1370-1381.
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Elizabeth A. Bobeck, Katie M. Meyer, Christian Helvig, Martin Petkovich & Mark E. Cook. (2013) Sevelamer Hydrochloride Binds Phosphate Released from Phytate in Chicks Fed 1α-Hydroxy Cholecalciferol. Journal of Renal Nutrition 23:1, pages 21-27.
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Atsushi InoueSatoshi MinakamiTakami KannoKazuharu Suyama. (2012) Highly Selective and Low-swelling Phosphate-binding Polymer for Hyperphosphatemia Therapy. Chemistry Letters 41:9, pages 932-933.
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Stefan Vegter, Keith Tolley, Michael S. Keith, Charmaine E. Lok, Steven D. Soroka & A. Ross Morton. (2012) Cost-Effectiveness of Lanthanum Carbonate in the Treatment of Hyperphosphatemia in Dialysis Patients: A Canadian Payer Perspective. Clinical Therapeutics 34:7, pages 1531-1543.
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Haesuk Park, Karen L. Rascati, Michael S. Keith, Paul Hodgkins, Michael Smyth, David Goldsmith & Ron Akehurst. (2011) Cost-Effectiveness of Lanthanum Carbonate versus Sevelamer Hydrochloride for the Treatment of Hyperphosphatemia in Patients with End-Stage Renal Disease: A US Payer Perspective. Value in Health 14:8, pages 1002-1009.
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Stefan Vegter, Keith Tolley, Michael S. Keith & Maarten J. Postma. (2011) Cost-Effectiveness of Lanthanum Carbonate in the Treatment of Hyperphosphatemia in Chronic Kidney Disease Before and During Dialysis. Value in Health 14:6, pages 852-858.
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Ye-Bo Zhou, Shao-Ju Jin, Yan Cai, Xu Teng, Li Chen, Chao-Shu Tang & Yong-Fen Qi. (2009) Lanthanum Acetate Inhibits Vascular Calcification Induced by Vitamin D3 Plus Nicotine in Rats. Experimental Biology and Medicine 234:8, pages 908-917.
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