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Original Article

The effect of orlistat and ezetimibe, alone or in combination, on serum LDL and small dense LDL cholesterol levels in overweight and obese patients with hypercholesterolaemia

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Pages 1919-1929 | Accepted 25 Apr 2008, Published online: 29 May 2008

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Read on this site (14)

T. D. Filippatos, M. Florentin, M. Georgoula & M. S. Elisaf. (2017) Pharmacological management of diabetic dyslipidemia. Expert Review of Clinical Pharmacology 10:2, pages 187-200.
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Anastazia A. Kei, Theodosios D. Filippatos & Moses S. Elisaf. (2016) The safety of ezetimibe and simvastatin combination for the treatment of hypercholesterolemia. Expert Opinion on Drug Safety 15:4, pages 559-569.
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Dragana Nikolic, Peter P Toth, Alessandra Ferlita, Vittoria Di Bartolo, Giuseppe Montalto, Maciej Banach & Manfredi Rizzo. (2014) Novel anti-obesity drugs and plasma lipids. Clinical Lipidology 9:2, pages 179-187.
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TD Filippatos, CS Derdemezis, PV Voulgari, V Tsimihodimos, MS Elisaf, AD Tselepis & AA Drosos. (2013) Effects of 12 months of treatment with disease-modifying anti-rheumatic drugs on low and high density lipoprotein subclass distribution in patients with early rheumatoid arthritis: a pilot study. Scandinavian Journal of Rheumatology 42:3, pages 169-175.
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Simant Baliarsingh, Neha Sharma & Ranadip Mukherjee. (2013) Serum uric acid: Marker for atherosclerosis as it is positively associated with “atherogenic index of plasma”. Archives of Physiology and Biochemistry 119:1, pages 27-31.
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Theodosios D Filippatos & Moses S Elisaf. (2011) Fenofibrate plus simvastatin (fixed-dose combination) for the treatment of dyslipidaemia. Expert Opinion on Pharmacotherapy 12:12, pages 1945-1958.
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Matilda Florentin, Evangelos N Liberopoulos, Dimitri P Mikhailidis & Moses S Elisaf. (2011) Emerging options in the treatment of dyslipidemias: a bright future?. Expert Opinion on Emerging Drugs 16:2, pages 247-270.
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Aris P Agouridis, Theodosios D Filippatos, Vasilios Tsimihodimos & Moses S Elisaf. (2011) Combinations of ezetimibe with nonstatin drug regimens affecting lipid metabolism. Expert Review of Cardiovascular Therapy 9:3, pages 355-366.
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Matilda Florentin, Evangelos N. Liberopoulos, Elisavet Moutzouri, Christos V. Rizos, Alexandros D. Tselepis & Moses S. Elisaf. (2011) The effect of simvastatin alone versus simvastatin plus ezetimibe on the concentration of small dense low-density lipoprotein cholesterol in subjects with primary hypercholesterolemia. Current Medical Research and Opinion 27:3, pages 685-692.
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Maria Sarigianni, Niki Katsiki & Dimitri P Mikhailidis. (2010) Ezetimibe in diabetes: more than cholesterol lowering?. Current Medical Research and Opinion 26:10, pages 2517-2520.
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Giuseppe Derosa, Pamela Maffioli, Sibilla AT Salvadeo, Ilaria Ferrari, Alessia Gravina, Roberto Mereu, Angela D'Angelo, Elena Fogari, Ilaria Palumbo, Sabrina Randazzo & Arrigo FG Cicero. (2010) Comparison of orlistat treatment and placebo in obese type 2 diabetic patients. Expert Opinion on Pharmacotherapy 11:12, pages 1971-1982.
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Katie S McClendon, Daniel M Riche & Gabriel Ikponmosa Uwaifo. (2009) Orlistat: current status in clinical therapeutics. Expert Opinion on Drug Safety 8:6, pages 727-744.
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ES Nakou, TD Filippatos, DN Kiortsis, CS Derdemezis, AD Tselepis, DP Mikhailidis & MS Elisaf. (2008) The effects of ezetimibe and orlistat, alone or in combination, on high-density lipoprotein (HDL) subclasses and HDL-associated enzyme activities in overweight and obese patients with hyperlipidaemia. Expert Opinion on Pharmacotherapy 9:18, pages 3151-3158.
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M Florentin, EN Liberopoulos, TD Filippatos, C Kostara, A Tselepis, DP Mikhailidis & M Elisaf. (2008) Effect of rimonabant, micronised fenofibrate and their combination on cardiometabolic risk factors in overweight/obese patients: a pilot study. Expert Opinion on Pharmacotherapy 9:16, pages 2741-2750.
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Dragana Nikolic, Niki Katsiki, Giuseppe Montalto, Esma Isenovic, Dimitri Mikhailidis & Manfredi Rizzo. (2013) Lipoprotein Subfractions in Metabolic Syndrome and Obesity: Clinical Significance and Therapeutic Approaches. Nutrients 5:3, pages 928-948.
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Elisavet Moutzouri, Evangelos N. Liberopoulos, Matilda Florentin, George Liamis & Moses S. Elisaf. (2012) Effects of Statin Monotherapy Versus Statin Plus Ezetimibe Combination on Serum Uric Acid Levels. Journal of Cardiovascular Pharmacology and Therapeutics 18:1, pages 13-18.
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Anastazia A. Kei, Theodosios D. Filippatos, Vasilios Tsimihodimos & Moses S. Elisaf. (2012) A review of the role of apolipoprotein C-II in lipoprotein metabolism and cardiovascular disease. Metabolism 61:7, pages 906-921.
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Theodosios D. Filippatos. (2012) A Review of Time Courses and Predictors of Lipid Changes with Fenofibric Acid-Statin Combination. Cardiovascular Drugs and Therapy 26:3, pages 245-255.
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Noboru Tamaki, Hiroaki Ueno, Yuta Morinaga, Tomomi Shiiya & Masamitsu Nakazato. (2012) Ezetimibe Ameliorates Atherosclerotic and Inflammatory Markers, Atherogenic Lipid Profiles, Insulin Sensitivity, and Liver Dysfunction in Japanese Patients with Hypercholesterolemia. Journal of Atherosclerosis and Thrombosis 19:6, pages 532-538.
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Karl Winkler, Stephan Jacob, Tina Müller-Schewe, Michael M. Hoffmann & Thomas Konrad. (2012) Ezetimibe alone and in combination lowers the concentration of small, dense low-density lipoproteins in type 2 diabetes mellitus. Atherosclerosis 220:1, pages 189-193.
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Matilda Florentin, Evangelos N. Liberopoulos, Costas C. Tellis, Christos S. Derdemezis, Moses Elisaf & Alexandros Tselepis. (2009) Effects of Rimonabant, as Monotherapy and in Combination With Fenofibrate or Ezetimibe, on Plasma Adipokine Levels: A Pilot Study. Angiology 61:4, pages 365-371.
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E. S. Nakou, T. D. Filippatos, A. P. Agouridis, C. Kostara, E. T. Bairaktari & M. S. Elisaf. (2010) The Effects of Ezetimibe and/or Orlistat on Triglyceride-Rich Lipoprotein Metabolism in Obese Hypercholesterolemic Patients. Lipids 45:5, pages 445-450.
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TD Filippatos, CS Derdemezis & MS Elisaf. (2009) Effects of orlistat, alone or combined with hypolipidemic drugs, on cardiovascular risk factors. Clinical Lipidology 4:3, pages 331-341.
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Manfredi Rizzo, Giovam Battista Rini, Giatgen A. Spinas & Kaspar Berneis. (2009) The effects of ezetimibe on LDL-cholesterol: Quantitative or qualitative changes?. Atherosclerosis 204:2, pages 330-333.
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