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Original Article

Population pharmacokinetics of rosuvastatin: implications of renal impairment, race, and dyslipidaemia

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Pages 2575-2585 | Accepted 01 Jul 2008, Published online: 30 Jul 2008

Keep up to date with the latest research on this topic with citation updates for this article.

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Merran Macpherson, Bengt Hamrén, Marjet J. A. M. Braamskamp, John J. P. Kastelein, Torbjörn Lundström & Paul D. Martin. (2015) Population pharmacokinetics of rosuvastatin in pediatric patients with heterozygous familial hypercholesterolemia. European Journal of Clinical Pharmacology 72:1, pages 19-27.
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Bruce K. Birmingham, Sarah R. Bujac, Robert Elsby, Connie T. Azumaya, Cheryl Wei, Yusong Chen, Rogelio Mosqueda-Garcia & Helen J. Ambrose. (2015) Impact of ABCG2 and SLCO1B1 polymorphisms on pharmacokinetics of rosuvastatin, atorvastatin and simvastatin acid in Caucasian and Asian subjects: a class effect?. European Journal of Clinical Pharmacology 71:3, pages 341-355.
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Bruce K. Birmingham, Sarah R. Bujac, Robert Elsby, Connie T. Azumaya, Julie Zalikowski, Yusong Chen, Kenneth Kim & Helen J. Ambrose. (2015) Rosuvastatin pharmacokinetics and pharmacogenetics in Caucasian and Asian subjects residing in the United States. European Journal of Clinical Pharmacology 71:3, pages 329-340.
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Hon-Kit Lee, Miao Hu, Sandra SH Lui, Chung-Shun Ho, Chun-Kwok Wong & Brian Tomlinson. (2013) Effects of polymorphisms in ABCG2 , SLCO1B1 , SLC10A1 and CYP2C9 / 19 on plasma concentrations of rosuvastatin and lipid response in Chinese patients . Pharmacogenomics 14:11, pages 1283-1294.
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Nathan W. Brunner, Krishnan Ramanathan, Hong Wang, Hude Quan & Nadia A. Khan. (2013) Effectiveness of Statin Prescribing on Reducing Mortality in South Asian, Chinese, and White Patients With Diabetes. Canadian Journal of Cardiology 29:8, pages 920-926.
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Ping Wang. (2011) Statin dose in Asians: is pharmacogenetics relevant?. Pharmacogenomics 12:11, pages 1605-1615.
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Ana Moreno, Jesús Fortún, Javier Graus, Miguel A. Rodriguez-Gandía, Carmen Quereda, María J. Pérez-Elías, Javier Nuño, Philip Wikman, Santiago Moreno & Rafael Bárcena. (2011) Severe rhabdomyolysis due to rosuvastatin in a liver transplant subject with human immunodeficiency virus and immunosuppressive therapy-related dyslipidemia. Liver Transplantation 17:3, pages 331-333.
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Juan Yang, Lu-jin Li, Kun Wang, Ying-chun He, Yu-cheng Sheng, Ling Xu, Xiao-hui Huang, Feng Guo & Qing-shan Zheng. (2010) Race differences: modeling the pharmacodynamics of rosuvastatin in Western and Asian hypercholesterolemia patients. Acta Pharmacologica Sinica 32:1, pages 116-125.
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Xue-Ning Li, Hong-Rong Xu, Wei-Li Chen, Nan-Nan Chu & Jun-Ren Zhu. (2010) Pharmacokinetics of rosuvastatin in healthy Chinese volunteers living in China: A randomized, open-label, ascending single- and multiple-dose study. Clinical Therapeutics 32:3, pages 575-587.
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Takahiko Aoyama, Takayuki Omori, Satoshi Watabe, Akemi Shioya, Takahiro Ueno, Noboru Fukuda & Yoshiaki Matsumoto. (2010) Pharmacokinetic/Pharmacodynamic Modeling and Simulation of Rosuvastatin Using an Extension of the Indirect Response Model by Incorporating a Circadian Rhythm. Biological and Pharmaceutical Bulletin 33:6, pages 1082-1087.
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Roger K. Verbeeck & Flora T. Musuamba. (2009) Pharmacokinetics and dosage adjustment in patients with renal dysfunction. European Journal of Clinical Pharmacology 65:8, pages 757-773.
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