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Original article

Efficacy, safety and tolerability of rivastigmine capsules in patients with probable vascular dementia: the VantagE study

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Pages 2561-2574 | Accepted 08 Jul 2008, Published online: 30 Jul 2008

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Marcelo L. Berthier, Guadalupe Dávila, Lisa Edelkraut, Diana López-Barroso, María José Torres-Prioris & Javier Tubío-Ordónez. 2020. Neurovascular Neuropsychology. Neurovascular Neuropsychology 465 500 .
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Milija D. Mijajlović, Aleksandra Pavlović, Michael Brainin, Wolf-Dieter Heiss, Terence J. Quinn, Hege B. Ihle-Hansen, Dirk M. Hermann, Einor Ben Assayag, Edo Richard, Alexander Thiel, Efrat Kliper, Yong-Il Shin, Yun-Hee Kim, SeongHye Choi, San Jung, Yeong-Bae Lee, Osman Sinanović, Deborah A. Levine, Ilana Schlesinger, Gillian Mead, Vuk Milošević, Didier Leys, Guri Hagberg, Marie Helene Ursin, Yvonne Teuschl, Semyon Prokopenko, Elena Mozheyko, Anna Bezdenezhnykh, Karl Matz, Vuk Aleksić, DafinFior Muresanu, Amos D. Korczyn & Natan M. Bornstein. (2017) Post-stroke dementia – a comprehensive review. BMC Medicine 15:1.
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Crossref
Eric E. Smith, Alicja Cieslak, Philip Barber, Jerry Chen, Yu‐Wei Chen, Ida Donnini, Jodi D. Edwards, Richard Frayne, Thalia S. Field, Janka Hegedus, Victoria Hanganu, Zahinoor Ismail, Jamila Kanji, Makoto Nakajima, Raza Noor, Stefano Peca, Demetrios Sahlas, Mukul Sharma, Luciano A. Sposato, Richard H. Swartz, Charlotte Zerna, Sandra E. Black & Vladimir Hachinski. (2017) Therapeutic Strategies and Drug Development for Vascular Cognitive Impairment. Journal of the American Heart Association 6:5.
Crossref
Erin McKay & Scott E. Counts. (2017) Multi-Infarct Dementia: A Historical Perspective. Dementia and Geriatric Cognitive Disorders Extra 7:1, pages 160-171.
Crossref
Martin DichgansDidier Leys. (2017) Vascular Cognitive Impairment. Circulation Research 120:3, pages 573-591.
Crossref
Shuhua Wang, Hongling Yang, Jie Zhang, Bin Zhang, Tao Liu, Lu Gan & Jiangang Zheng. (2016) Efficacy and safety assessment of acupuncture and nimodipine to treat mild cognitive impairment after cerebral infarction: a randomized controlled trial. BMC Complementary and Alternative Medicine 16:1.
Crossref
M. Planton, J.-F. Albucher & J. Pariente. (2016) Disturbi cognitivi di origine vascolare. EMC - Neurologia 16:4, pages 1-12.
Crossref
Ayesha Khan, Raj N. Kalaria, Anne Corbett & Clive Ballard. (2016) Update on Vascular Dementia. Journal of Geriatric Psychiatry and Neurology 29:5, pages 281-301.
Crossref
Hermann AM Mucke. (2016) Drug repurposing for vascular dementia: overview and current developments. Future Neurology 11:3, pages 215-225.
Crossref
Jianping Jia, Cuibai Wei, Junhua Liang, Aihong Zhou, Xiumei Zuo, Haiqing Song, Liyong Wu, Xiaochun Chen, Shengdi Chen, Junjian Zhang, Jiang Wu, Kai Wang, Lan Chu, Dantao Peng, Peiyuan Lv, Hongzhi Guo, Xiaoyuan Niu, Yingzhu Chen, Wanli Dong, Xiujie Han, Boyan Fang, Mao Peng, Dan Li, Qian Jia & Liyuan Huang. (2015) The effects of DL‐3‐n‐butylphthalide in patients with vascular cognitive impairment without dementia caused by subcortical ischemic small vessel disease: A multicentre, randomized, double‐blind, placebo‐controlled trial. Alzheimer's & Dementia 12:2, pages 89-99.
Crossref
Nenad Đukić, Mihailo Nešković, Milorad Ševković & Đorđe Radak. (2016) Vascular dementia revised. Medicinska istrazivanja 50:2, pages 23-29.
Crossref
Yael D Reijmer, Susanne J van Veluw & Steven M Greenberg. (2015) Ischemic brain injury in cerebral amyloid angiopathy. Journal of Cerebral Blood Flow & Metabolism 36:1, pages 40-54.
Crossref
Andrew E. Budson & Paul R. Solomon. 2016. Memory Loss, Alzheimer's Disease, and Dementia. Memory Loss, Alzheimer's Disease, and Dementia 80 91 .
John T O'Brien & Alan Thomas. (2015) Vascular dementia. The Lancet 386:10004, pages 1698-1706.
Crossref
Meera Sheffrin, Yinghui Miao, W. John Boscardin & Michael A. Steinman. (2015) Weight Loss Associated with Cholinesterase Inhibitors in Individuals with Dementia in a National Healthcare System. Journal of the American Geriatrics Society 63:8, pages 1512-1518.
Crossref
Aaron Ritter & Jagan A. Pillai. (2015) Treatment of Vascular Cognitive Impairment. Current Treatment Options in Neurology 17:8.
Crossref
Naveed Malek & John Greene. (2014) Cognition enhancers for the treatment of dementia. Scottish Medical Journal 60:1, pages 44-49.
Crossref
Soo-Jung HahnNam-Jong Paik. (2015) Pharmacological Treatment of Dementia. Brain & Neurorehabilitation 8:1, pages 19.
Crossref
A. Robles Bayón & F. Gude Sampedro. (2014) Inappropriate treatments for patients with cognitive decline. Neurología (English Edition) 29:9, pages 523-532.
Crossref
A. Robles Bayón & F. Gude Sampedro. (2014) Prescripciones inconvenientes en el tratamiento del paciente con deterioro cognitivo. Neurología 29:9, pages 523-532.
Crossref
Brian P. Gomoll, Brandon D. Sanders & Maria T. Caserta. (2014) Psychopharmacologic Treatments for Alzheimer Disease and Related Dementias. Psychopharm Review 49:1, pages 9-16.
Crossref
HyungSub Shim. (2013) Vascular Cognitive Impairment and Post-Stroke Cognitive Deficits. Current Neurology and Neuroscience Reports 14:1.
Crossref
Laura Silveira-Moriyama, Egberto R. Barbosa, Paulo Caramelli, Jan Zijlmans & Andrew J. Lees. 2014. Movement Disorders in Dementias. Movement Disorders in Dementias 199 211 .
Jacqueline Birks, Bernadette McGuinness & David Craig. (2013) Rivastigmine for vascular cognitive impairment. Cochrane Database of Systematic Reviews.
Crossref
Roger M. Lane & Yunsheng He. (2012) Butyrylcholinesterase genotype and gender influence Alzheimer's disease phenotype. Alzheimer's & Dementia 9:2.
Crossref
Penglian Wang, Yongjun Wang, Tao Feng, Xingquan Zhao, Yong Zhou, Yilong Wang, Weixiong Shi & Yi Ju. (2012) Rationale and design of a double-blind, placebo-controlled, randomized trial to evaluate the safety and efficacy of nimodipine in preventing cognitive impairment in ischemic cerebrovascular events (NICE). BMC Neurology 12:1.
Crossref
Andrius Baskys & Jin-xiang Cheng. (2012) Pharmacological prevention and treatment of vascular dementia: Approaches and perspectives. Experimental Gerontology 47:11, pages 887-891.
Crossref
John T O’BrienAlistair Burns. (2010) Clinical practice with anti-dementia drugs: a revised (second) consensus statement from the British Association for Psychopharmacology. Journal of Psychopharmacology 25:8, pages 997-1019.
Crossref
Deborah A. Levine & Kenneth M. Langa. (2011) Vascular Cognitive Impairment: Disease Mechanisms and Therapeutic Implications. Neurotherapeutics 8:3, pages 361-373.
Crossref
Yan Deschaintre, Fadi Massoud & Gabriel C. Léger. 2011. Case Studies in Dementia. Case Studies in Dementia 47 54 .
W. R. Brown & C. R. Thore. (2011) Review: Cerebral microvascular pathology in ageing and neurodegeneration. Neuropathology and Applied Neurobiology 37:1, pages 56-74.
Crossref
Ae Young Lee. (2011) Vascular Dementia. Chonnam Medical Journal 47:2, pages 66.
Crossref
Andrew E. Budson & Paul R. Solomon. 2011. Memory Loss. Memory Loss 91 103 .
Dina Zekry & Gabriel Gold. (2010) Management of Mixed Dementia. Drugs & Aging 27:9, pages 715-728.
Crossref
Leonardo Pantoni. (2010) Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges. The Lancet Neurology 9:7, pages 689-701.
Crossref
Gustavo C. RománStephen SallowaySandra E. BlackDonald R. RoyallCharles DeCarliMichael W. WeinerMargaret MolineDinesh KumarRachel SchindlerHolly Posner. (2010) Randomized, Placebo-Controlled, Clinical Trial of Donepezil in Vascular Dementia. Stroke 41:6, pages 1213-1221.
Crossref
María Jesús González Moneo. (2010) Utilidad de los fármacos en la demencia. FMC - Formación Médica Continuada en Atención Primaria 17:5, pages 326-335.
Crossref
Roger M. Lane & Yunsheng He. (2009) Emerging hypotheses regarding the influences of butyrylcholinesterase-K variant, APOE ε4, and hyperhomocysteinemia in neurodegenerative dementias. Medical Hypotheses 73:2, pages 230-250.
Crossref
. (2009) Current awareness: Pharmacoepidemiology and drug safety. Pharmacoepidemiology and Drug Safety 18:3.
Crossref

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