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Original article

Prefilled insulin device with reduced injection force: patient perception and accuracy

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Pages 2545-2549 | Accepted 08 Jul 2008, Published online: 29 Jul 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (20)

Andreas E. Schneider & Jakob Lange. (2018) Pen devices for self-injection: contrasting measured injection force with users’ perceived ease of injection. Expert Opinion on Drug Delivery 15:2, pages 115-125.
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Jakob Lange, Leos Urbanek & Stefan Burren. (2016) Development of devices for self-injection: using tribological analysis to optimize injection force. Medical Devices: Evidence and Research 9, pages 93-103.
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Anne-Marie Kappelgaard & Niels-Åge Hansen. (2013) Comparison of injection dose force, accuracy and precision among three growth hormone injection devices. Expert Review of Medical Devices 10:3, pages 321-327.
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Andreas Pfützner, Timothy Bailey, Carlos Campos, Douglas Kahn, Ellen Ambers, Marcus Niemeyer, German Guerrero, David Klonoff & Irina Nayberg. (2013) Accuracy and preference assessment of prefilled insulin pen versus vial and syringe with diabetes patients, caregivers, and healthcare professionals. Current Medical Research and Opinion 29:5, pages 475-481.
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David Oyer, Marcus Niemeyer & Alan Moses. (2012) Empowering People with Diabetes: Improving Perceptions and Outcomes with Technical Advances in Insulin Pens. Postgraduate Medicine 124:5, pages 110-120.
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Christina Schipper, Petra Musholt, Marcus Niemeyer, Marianne Qvist, Andrea Löffler, Thomas Forst & Andreas Pfützner. (2012) Patient device assessment evaluation of two insulin injection devices in a mixed cohort of insulin-treated patients with type 1 or type 2 diabetes mellitus. Current Medical Research and Opinion 28:8, pages 1297-1303.
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S. Garg, T. Bailey, T. DeLuzio & D. Pollom. (2011) Preference for a new prefilled insulin pen compared with the original pen. Current Medical Research and Opinion 27:12, pages 2323-2333.
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David Oyer, Parth Narendran, Marianne Qvist, Marcus Niemeyer & Daniel A Nadeau. (2011) Ease of use and preference of a new versus widely available prefilled insulin pen assessed by people with diabetes, physicians and nurses. Expert Opinion on Drug Delivery 8:10, pages 1259-1269.
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Jakob O Wielandt, Marcus Niemeyer, Marianne R Hansen, Ditlef Bucher & Niels B Thomsen. (2011) An assessment of dose accuracy and injection force of a novel prefilled insulin pen: comparison with a widely used prefilled insulin pen. Expert Opinion on Drug Delivery 8:10, pages 1271-1276.
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T. Bailey, J. Thurman, M. Niemeyer & G. Schmeisl. (2011) Usability and preference evaluation of a prefilled insulin pen with a novel injection mechanism by people with diabetes and healthcare professionals. Current Medical Research and Opinion 27:10, pages 2043-2052.
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Estella M Davis, Emily L Sexson, Mikayla L Spangler & Pamela A Foral. (2010) An evaluation of prefilled insulin pens: a focus on the Next Generation FlexPen®. Medical Devices: Evidence and Research 3, pages 41-50.
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L. Niskanen. (2010) A clinical and health economic review of a prefilled insulin pen. Current Medical Research and Opinion 26:10, pages 2431-2439.
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Debra A. Ignaut, Michael R. Opincar, Paula E. Clark, Melanie K. Palaisa & Sheila M. Lenox. (2009) Engineering study comparing injection force and dose accuracy between two prefilled insulin injection pens. Current Medical Research and Opinion 25:12, pages 2829-2833.
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Michael Opincar & Debra Ignaut. (2009) Comment and reply on: Evaluation of injection force of three insulin delivery pens. Expert Opinion on Pharmacotherapy 10:14, pages 2391-2392.
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T Asakura, H Seino, M Kageyama & N Yohkoh. (2009) Evaluation of injection force of three insulin delivery pens. Expert Opinion on Pharmacotherapy 10:9, pages 1389-1393.
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Andreas Pfützner. (2009) FlexPen® for the delivery of insulin: accuracy, injection force and patient preference. Expert Review of Medical Devices 6:2, pages 115-123.
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J Rissler, C Jørgensen, M Rye Hansen & N-A Hansen. (2008) Evaluation of the injection force dynamics of a modified prefilled insulin pen. Expert Opinion on Pharmacotherapy 9:13, pages 2217-2222.
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A Pfützner, T Asakura, B Sommavilla & WC Lee. (2008) Insulin delivery with FlexPen®: dose accuracy, patient preference and adherence. Expert Opinion on Drug Delivery 5:8, pages 915-925.
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Articles from other publishers (21)

Victoria G. Muir, Taimoor H. Qazi, Junwen Shan, Jürgen Groll & Jason A. Burdick. (2021) Influence of Microgel Fabrication Technique on Granular Hydrogel Properties. ACS Biomaterials Science & Engineering 7:9, pages 4269-4281.
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Christopher M. Kappes, James R. Kershner, Tina M. Morwick & Sheila M. Corrigan. (2017) Dose Accuracy, Injection Force, and Usability Assessment of a New Half-Unit, Prefilled Insulin Pen. Journal of Diabetes Science and Technology 12:2, pages 364-372.
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Tina M. Rees, Amanda H. Lennartz & Debra A. Ignaut. (2015) A Comparison of Glide Force Characteristics Between 2 Prefilled Insulin Lispro Pens. Journal of Diabetes Science and Technology 9:2, pages 316-319.
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Hitomi Fujii, Mikako Baba, Takayuki Mori, Yoshiko Asada, Akihito Nonaka, Yuko Watanabe, Yoshiaki Kawagoe, Miyuki Nogawa, Takaichi Miyakawa & Masafumi Kitaoka. (2014) Practical Experience With a New Prefilled Pen Device for a Long-Acting Insulin Analog in Japan. Journal of Diabetes Science and Technology 8:4, pages 904-905.
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Robert M. Cuddihy & Sarah K. Borgman. (2013) Considerations for Diabetes. American Journal of Therapeutics 20:6, pages 694-702.
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Janine Bohnet, Mario Schmitz, Stefan Kamlot & Mona Abdel-Tawab. (2013) Dosing Accuracy and Insulin Flow Rate Characteristics of a New Disposable Insulin Pen, FlexTouch, Compared with SoloSTAR. Journal of Diabetes Science and Technology 7:4, pages 1021-1026.
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Meike KrzywonThomas van der BurgUwe FuhrManfred Schubert-ZsilaveczMona Abdel-Tawab. (2012) Study on the Dosing Accuracy of Commonly Used Disposable Insulin Pens. Diabetes Technology & Therapeutics 14:9, pages 804-809.
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Andreas Liebl, Vinay Prusty, Paul Valensi, Ryuzo Kawamori, Jens Sandahl Christiansen, Andrew J. Palmer, Per Balschmidt, Robert Ligthelm & Viswanathan Mohan. (2012) Ten Years of Experience with Biphasic Insulin Aspart 30. Drugs 72:11, pages 1495-1520.
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Geralyn R. Spollett. (2012) Improved Disposable Insulin Pen Devices Provide an Alternative to Vials and Syringes for Insulin Administration. Diabetes Spectrum 25:2, pages 117-122.
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Hans HemmingsenMarcus NiemeyerMarianne Rye HansenDitlef BucherNiels Bjerrum Thomsen. (2011) A Prefilled Insulin Pen with a Novel Injection Mechanism and a Lower Injection Force than Other Prefilled Insulin Pens. Diabetes Technology & Therapeutics 13:12, pages 1207-1211.
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Jakob Oest Wielandt, Marcus Niemeyer, Marianne Rye Hansen, Ditlef Bucher & Niels Bjerrum Thomsen. (2011) FlexTouch: A Prefilled Insulin Pen with a Novel Injection Mechanism with Consistent High Accuracy at Low- (1 U), Medium- (40 U), and High- (80 U) Dose Settings. Journal of Diabetes Science and Technology 5:5, pages 1195-1199.
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Melissa L Magwire. (2011) Addressing Barriers to Insulin Therapy: The Role of Insulin Pens. American Journal of Therapeutics 18:5, pages 392-402.
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Birtha HansenSøren K. LilleøreGitte Ter-Borch. (2011) Needle with a Novel Attachment Versus Conventional Screw-Thread Needles: A Preference and Usability Test Among Adults with Diabetes and Impaired Manual Dexterity. Diabetes Technology & Therapeutics 13:5, pages 579-585.
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Anne-Marie Kappelgaard, Søren Mikkelsen, Thomas Kamp Knudsen & Gitte Schøning Fuchs. (2011) Patient preference for a new growth hormone injection device: results of an open-label study in Japanese pediatric patients. Journal of Pediatric Endocrinology and Metabolism 24:7-8.
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Andreas Pfützner & Bärbel Sommavilla. (2010) Comment on Comparative Device Assessments. The Diabetes Educator 36:5, pages 710-712.
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Teresa L. Pearson. (2010) Practical Aspects of Insulin Pen Devices. Journal of Diabetes Science and Technology 4:3, pages 522-531.
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Jean-Louis Selam. (2010) Evolution of Diabetes Insulin Delivery Devices. Journal of Diabetes Science and Technology 4:3, pages 505-513.
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Gitte Schøning Fuchs, Søren Mikkelsen, Thomas Kamp Knudsen & Anne-Marie Kappelgaard. (2009) Ease of use and acceptability of a new pen device for the administration of growth hormone therapy in pediatric patients: An open-label, uncontrolled usability test. Clinical Therapeutics 31:12, pages 2906-2914.
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Morten DonsmarkLars HeroldCarsten Mølgård Kristensen. (2009) A Comparison of Injection Force and Dosage Scale Size Between NovoPen ® 3 and NovoPen ® 4 . Diabetes Technology & Therapeutics 11:9, pages 581-585.
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Alexander Weise, Johannes W. Pfützner, Julia Borig, Anna M. Pfützner, Michael Safinowski, Heike Hänel, Petra B. Musholt & Andreas Pfützner. (2009) Comparison of the Dose Accuracy of Prefilled Insulin Pens. Journal of Diabetes Science and Technology 3:1, pages 149-153.
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Tanja Reimer, Cloth Hohberg, Anke H. Pfützner, Christina Jørgensen, Klaus H. Jensen & Andreas Pfützner. (2008) Intuitiveness, instruction time, and patient acceptance of a prefilled insulin delivery device and a reusable insulin delivery device in a randomized, open-label, crossover handling Study in patients with type 2 diabetes. Clinical Therapeutics 30:12, pages 2252-2262.
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