277
Views
59
CrossRef citations to date
0
Altmetric
Commentary

Do fluoroquinolones predispose patients to Clostridium difficile associated disease? A review of the evidence

, , , &
Pages 329-333 | Accepted 02 Nov 2007, Published online: 06 Dec 2007

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (7)

Katrina L Schmid. (2021) Fluoroquinolones are a potent form of chemotherapy. Clinical and Experimental Optometry 104:3, pages 412-416.
Read now
Mark Fagan, Morten Lindbæk, Harald Reiso & Dag Berild. (2014) A simple intervention to reduce inappropriate ciprofloxacin prescribing in the emergency department. Scandinavian Journal of Infectious Diseases 46:7, pages 481-485.
Read now
Chaitanya Pant, Abhishek Deshpande, Muhammad A. Altaf, Anil Minocha & Thomas J. Sferra. (2013) Clostridium difficile infection in children: a comprehensive review. Current Medical Research and Opinion 29:8, pages 967-984.
Read now
Cédric Rafat, Isabelle Debrix & Alexandre Hertig. (2013) Levofloxacin for the treatment of pyelonephritis. Expert Opinion on Pharmacotherapy 14:9, pages 1241-1253.
Read now
Abhishek Deshpande, Vinay Pasupuleti, Chaitanya Pant, Geraldine Hall & Anil Jain. (2010) Potential value of repeat stool testing for Clostridium difficile stool toxin using enzyme immunoassay?. Current Medical Research and Opinion 26:11, pages 2635-2641.
Read now
Marilee D. Obritsch, Jeffrey S. Stroup, Ryan M. Carnahan & David N. Scheck. (2010) Clostridium Difficile–Associated Diarrhea in a Tertiary Care Medical Center. Baylor University Medical Center Proceedings 23:4, pages 363-367.
Read now

Articles from other publishers (52)

Ian M. Paquette & David B. Stewart. 2022. The ASCRS Textbook of Colon and Rectal Surgery. The ASCRS Textbook of Colon and Rectal Surgery 879 891 .
Aislinn D. Rowan-Nash, Rafael Araos, Erika M.C. D'Agata & Peter Belenky. (2020) Antimicrobial Resistance Gene Prevalence in a Population of Patients with Advanced Dementia Is Related to Specific Pathobionts. iScience 23:3, pages 100905.
Crossref
N. Khanafer, N. Daneman, T. Greene, A. Simor, P. Vanhems, M. Samore & K.A. Brown. (2018) Susceptibilities of clinical Clostridium difficile isolates to antimicrobials: a systematic review and meta-analysis of studies since 1970. Clinical Microbiology and Infection 24:2, pages 110-117.
Crossref
Evan Martens & Arnold L. Demain. 2017. Microbial Resources. Microbial Resources 149 168 .
Toru Otori, Sumio Matzno, Atushi Kawase, Masahiro Iwaki, Tetsutaro Kimachi, Keiji Nishiwaki, William C Figoni, Ryuta Tominaga, Mai Asahide, Mayumi Nishikata, Yoshikazu Ishii & Kenji Matsuyama. (2016) Development of hemiacetal esterified levofloxacin to prevent chelation with metal-containing drugs. Journal of Pharmacy and Pharmacology 68:12, pages 1527-1534.
Crossref
H. Harvala, E. Alm, T. Åkerlund & K. Rizzardi. (2016) Emergence and spread of moxifloxacin-resistant Clostridium difficile ribotype 231 in Sweden between 2006 and 2015. New Microbes and New Infections 14, pages 58-66.
Crossref
Christos A. Grigoras, Fainareti N. Zervou, Ioannis M. Zacharioudakis, Constantinos I. Siettos & Eleftherios Mylonakis. (2016) Isolation of C. difficile Carriers Alone and as Part of a Bundle Approach for the Prevention of Clostridium difficile Infection (CDI): A Mathematical Model Based on Clinical Study Data. PLOS ONE 11:6, pages e0156577.
Crossref
Guillermo Alvarez-Calatayud & Abelardo Margolles. (2016) Dual-coated lactic acid bacteria: an emerging innovative technology in the field of probiotics. Future Microbiology 11:3, pages 467-475.
Crossref
. 2016. Meyler's Side Effects of Drugs. Meyler's Side Effects of Drugs 368 381 .
Françoise Van Bambeke. (2015) Delafloxacin, a non-zwitterionic fluoroquinolone in Phase III of clinical development: evaluation of its pharmacology, pharmacokinetics, pharmacodynamics and clinical efficacy. Future Microbiology 10:7, pages 1111-1123.
Crossref
Mamun-Ur Rashid, Egijia Zaura, Mark J. Buijs, Bart J. F. Keijser, Wim Crielaard, Carl Erik Nord & Andrej Weintraub. (2015) Determining the Long-term Effect of Antibiotic Administration on the Human Normal Intestinal Microbiota Using Culture and Pyrosequencing Methods. Clinical Infectious Diseases 60:suppl_2, pages S77-S84.
Crossref
Aaron Lloyd, Vinay Pasupuleti, Priyaleela Thota, Chaitanya Pant, David D.K. Rolston, Adrian V. Hernandez, Vicente A. Benites-Zapata, Thomas G. Fraser, Curtis J. Donskey & Abhishek Deshpande. (2015) Accuracy of loop-mediated isothermal amplification for the diagnosis of Clostridium difficile infection: a systematic review. Diagnostic Microbiology and Infectious Disease 82:1, pages 4-10.
Crossref
Anca Trifan. (2014) Impact of Clostridium difficile infection on inflammatory bowel disease outcome: A review . World Journal of Gastroenterology 20:33, pages 11736.
Crossref
Sunny Park, Miseon Park & Fatemeh Rafii. (2013) Comparative transcription analysis and toxin production of two fluoroquinolone-resistant mutants of Clostridium perfringens. BMC Microbiology 13:1.
Crossref
S. Singer, K. Oberdorfer, R. Schwarz, S. Schütt, D. Bertsch, M. Holfelder, C. Wendt & H. Hof. (2013) Kalkulierte Antibiotikatherapie von Harnwegsinfektionen bei älteren FrauenCalculated antibiotic therapy of urinary tract infections in elderly women. Der Gynäkologe 46:11, pages 847-857.
Crossref
Abhishek Deshpande, Vinay Pasupuleti, Sherif B. Mossad, Marie Budev, Steven K. Schmitt, Rebecca Corey, Bijan Eghtesad, Steven D. Mawhorter, Adrian V. Hernandez, Anil Jain & Robin K. Avery. (2013) Use of Lactobacillus in Prevention of Recurrences of Clostridium difficile Infection in Solid Organ Transplant Recipients. Infectious Diseases in Clinical Practice 21:5, pages 292-298.
Crossref
Joanne Levin, Linda S. Riley, Christine Parrish, Daniel English & Sehoon Ahn. (2013) The effect of portable pulsed xenon ultraviolet light after terminal cleaning on hospital-associated Clostridium difficile infection in a community hospital. American Journal of Infection Control 41:8, pages 746-748.
Crossref
Michael John Aldape, Aaron Eugene Packham, Drew William Nute, Amy Evelyn Bryant & Dennis Leroy Stevens. (2013) Effects of ciprofloxacin on the expression and production of exotoxins by Clostridium difficile. Journal of Medical Microbiology 62:5, pages 741-747.
Crossref
Winfried V. KernOscar MarchettiLubos DrgonaHamdi AkanMickel AounMurat AkovaRobrecht de BockMarianne PaesmansClaudio ViscoliThierry Calandra. (2013) Oral Antibiotics for Fever in Low-Risk Neutropenic Patients With Cancer: A Double-Blind, Randomized, Multicenter Trial Comparing Single Daily Moxifloxacin With Twice Daily Ciprofloxacin Plus Amoxicillin/Clavulanic Acid Combination Therapy—EORTC Infectious Diseases Group Trial XV. Journal of Clinical Oncology 31:9, pages 1149-1156.
Crossref
Winfried V. Kern. 2013. Arzneiverordnungs-Report 2013. Arzneiverordnungs-Report 2013 303 330 .
Evie H. Carchman, Andrew B. Peitzman, Richard L. Simmons & Brian S. Zuckerbraun. (2012) The role of acute care surgery in the treatment of severe, complicated Clostridium difficile–associated disease. Journal of Trauma and Acute Care Surgery 73:4, pages 789-800.
Crossref
H. Hof, M. Holfelder, A. Fahr & K. Oberdorfer. (2012) Kalkulierte Antibiotikatherapie von Harnwegsinfektionen bei ÄlterenCalculated antibiotic therapy of urinary tract infections in the elderly. Der Nephrologe 7:5, pages 431-433.
Crossref
Michelle D Cairns, Richard A Stabler, Nandini Shetty & Brendan W Wren. (2012) The continually evolving Clostridium difficile species . Future Microbiology 7:8, pages 945-957.
Crossref
Spencer E. Harpe, Timothy J. Inocencio, Amy L. Pakyz, Michael J. Oinonen & Ronald E. Polk. (2012) Characterization of Continued Antibacterial Therapy After Diagnosis of Hospital-Onset Clostridium difficile Infection: Implications for Antimicrobial Stewardship. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 32:8, pages 744-754.
Crossref
Abhishek Deshpande, Chaitanya Pant, Vinay Pasupuleti, David D.K. Rolston, Anil Jain, Narayan Deshpande, Priyaleela Thota, Thomas J. Sferra & Adrian V. Hernandez. (2012) Association Between Proton Pump Inhibitor Therapy and Clostridium difficile Infection in a Meta-Analysis. Clinical Gastroenterology and Hepatology 10:3, pages 225-233.
Crossref
Ulrich Schwabe & Dieter PaffrathWinfried V. Kern. 2012. Arzneiverordnungs-Report 2012. Arzneiverordnungs-Report 2012 311 338 .
Chaitanya Pant, Thomas J. Sferra, Abhishek Deshpande & Anil Minocha. (2011) Clinical approach to severe Clostridium difficile infection: Update for the hospital practitioner. European Journal of Internal Medicine 22:6, pages 561-568.
Crossref
Abhishek Deshpande, Vinay Pasupuleti, David D.K. Rolston, Anil Jain, Narayan Deshpande, Chaitanya Pant & Adrian V. Hernandez. (2011) Diagnostic Accuracy of Real-time Polymerase Chain Reaction in Detection of Clostridium difficile in the Stool Samples of Patients With Suspected Clostridium difficile Infection: A Meta-Analysis. Clinical Infectious Diseases 53:7, pages e81-e90.
Crossref
Abhishek Deshpande, Vinay Pasupuleti, Preethi Patel, Gati Ajani, Geraldine Hall, Bo Hu, Anil Jain & David D.K. Rolston. (2011) Repeat Stool Testing to Diagnose Clostridium difficile Infection Using Enzyme Immunoassay Does Not Increase Diagnostic Yield. Clinical Gastroenterology and Hepatology 9:8, pages 665-669.e1.
Crossref
Anne E. Boyer, Maribel Gallegos-Candela, Renato C. Lins, Zsuzsanna Kuklenyik, Adrian Woolfitt, Hercules Moura, Suzanne Kalb, Conrad P. Quinn & John R. Barr. (2011) Quantitative Mass Spectrometry for Bacterial Protein Toxins — A Sensitive, Specific, High-Throughput Tool for Detection and Diagnosis. Molecules 16:3, pages 2391-2413.
Crossref
Marco Berning, Susanne Krasz & Stephan Miehlke. (2010) Should quinolones come first in Helicobacter pylori therapy? . Therapeutic Advances in Gastroenterology 4:2, pages 103-114.
Crossref
Cormac G. M. Gahan, Gerald C. O’Sullivan & J. Kevin Collins. 2011. Probiotic Bacteria and Enteric Infections. Probiotic Bacteria and Enteric Infections 113 130 .
Winfried V. Kern. 2011. Arzneiverordnungs-Report 2011. Arzneiverordnungs-Report 2011 311 338 .
Paul A. Hoskisson & Jack T. Trevors. (2010) Shifting trends in pathogen dynamics on a changing planet. Antonie van Leeuwenhoek 98:4, pages 423-427.
Crossref
T. Norén, I. Alriksson, T. Åkerlund, L.G. Burman & M. Unemo. (2010) In vitro susceptibility to 17 antimicrobials of clinical Clostridium difficile isolates collected in 1993–2007 in Sweden. Clinical Microbiology and Infection 16:8, pages 1104-1110.
Crossref
Elisabet Lönnermark, Vanda Friman, Georg Lappas, Torsten Sandberg, Anna Berggren & Ingegerd Adlerberth. (2010) Intake of Lactobacillus plantarum Reduces Certain Gastrointestinal Symptoms During Treatment With Antibiotics. Journal of Clinical Gastroenterology 44:2, pages 106-112.
Crossref
Chaitanya PantPhillip MadoniaAnil MinochaKenneth ManasPaul JordanPat Bass. (2023) Laboratory Markers as Predictors of Mortality in Patients with Clostridium difficile Infection. Journal of Investigative Medicine 58:1, pages 43-45.
Crossref
Natascia Corti, Alexander Imhof & Christa Wenger. 2010. Side Effects of Drugs Annual 32 - A worldwide yearly survey of new data and trends in adverse drug reactions and interactions. Side Effects of Drugs Annual 32 - A worldwide yearly survey of new data and trends in adverse drug reactions and interactions 461 489 .
Winfried V. Kern. 2010. Arzneiverordnungs-Report 2010. Arzneiverordnungs-Report 2010 303 330 .
David Goulding, Harold Thompson, Jenny Emerson, Neil F. Fairweather, Gordon Dougan & Gill R. Douce. (2009) Distinctive Profiles of Infection and Pathology in Hamsters Infected with Clostridium difficile Strains 630 and B1 . Infection and Immunity 77:12, pages 5478-5485.
Crossref
Cécile Denève, Sylvie Bouttier, Bruno Dupuy, Frédéric Barbut, Anne Collignon & Claire Janoir. (2009) Effects of Subinhibitory Concentrations of Antibiotics on Colonization Factor Expression by Moxifloxacin-Susceptible and Moxifloxacin-Resistant Clostridium difficile Strains . Antimicrobial Agents and Chemotherapy 53:12, pages 5155-5162.
Crossref
Tomasz Kaczmarzyk. (2009) Abuse of Antibiotic Prophylaxis in Third Molar Surgeries. Journal of Oral and Maxillofacial Surgery 67:11, pages 2551-2552.
Crossref
Chaitanya Pant, Phillip Madonia & Anil Minocha. (2009) Does PPI therapy predispose to Clostridium difficile infection?. Nature Reviews Gastroenterology & Hepatology 6:9, pages 555-557.
Crossref
Juan-Ignacio Alós. (2009) Quinolonas. Enfermedades Infecciosas y Microbiología Clínica 27:5, pages 290-297.
Crossref
Klaus Kaier, Christian Hagist, Uwe Frank, Andreas Conrad & Elisabeth Meyer. (2015) Two Time-Series Analyses of the Impact of Antibiotic Consumption and Alcohol-Based Hand Disinfection on the Incidences of Nosocomial Methicillin-Resistant Staphylococcus aureus Infection and Clostridium difficile Infection . Infection Control & Hospital Epidemiology 30:4, pages 346-353.
Crossref
Karl Weiss. (2009) Clostridium difficile and fluoroquinolones: is there a link?. International Journal of Antimicrobial Agents 33, pages S29-S32.
Crossref
Gary J. Noel. (2009) A Review of Levofloxacin for the Treatment of Bacterial Infections. Clinical Medicine. Therapeutics 1, pages CMT.S28.
Crossref
Winfried V. Kern. 2009. Arzneiverordnungs-Report 2009. Arzneiverordnungs-Report 2009 283 308 .
Xavier Calvet. (2008) What is the best first-line therapy for Helicobacter pylori infection?. Nature Clinical Practice Gastroenterology & Hepatology 5:11, pages 606-607.
Crossref
Lynne V McFarland. (2008) Antibiotic-associated diarrhea: epidemiology, trends and treatment. Future Microbiology 3:5, pages 563-578.
Crossref
F. Fitzpatrick, G. McIlvenny, A. Oza, R.G. Newcombe, H. Humphreys, R. Cunney, N. Murphy, R. Ruddy, G. Reid, R. Bailie, C. Lavelle, L. Doherty & E.T.M. Smyth. (2008) Hospital Infection Society Prevalence Survey of Healthcare Associated Infection 2006: comparison of results between Northern Ireland and the Republic of Ireland. Journal of Hospital Infection 69:3, pages 265-273.
Crossref
Winfried V. Kern. 2008. Arzneiverordnungs-Report 2008. Arzneiverordnungs-Report 2008 279 304 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.