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Current Medical Research and Opinion Volume 24, 2008 - Issue 3
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Original Article

A study of the pharmacokinetic interactions of the direct renin inhibitor aliskiren with allopurinol, celecoxib and cimetidine in healthy subjects

Surya Ayalasomayajula Novartis Pharmaceuticals Corporation, East Hanover, NJ, USACorrespondence[email protected]
,
Stéphanie Tchaloyan Novartis Pharma AG, Basel, Switzerland
,
Ching-Ming Yeh Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA
,
Marie-Noelle Bizot Novartis Pharma SAS, Rueil-Malmaison, France
,
Hans Armin Dieterich Novartis Pharma AG, Basel, Switzerland
,
Dan Howard Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA
&
William P. Dole Novartis Institutes for Biomedical Research, Cambridge, MA, USA
 show all
Pages 717-726 | Accepted 14 Dec 2007, Published online: 29 Jan 2008

Citations (19)

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Nicholas Moore, Charles Pollack & Paul Butkerait. (2015) Adverse drug reactions and drug–drug interactions with over-the-counter NSAIDs. Therapeutics and Clinical Risk Management 11, pages 1061-1075.
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Haroonur Rashid. (2008) Direct renin inhibition: an evaluation of the safety and tolerability of aliskiren. Current Medical Research and Opinion 24:9, pages 2627-2637.
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Sujata Vaidyanathan, Mojdeh Maboudian, Vance Warren, Ching-Ming Yeh, Hans Armin Dieterich, Dan Howard & William P. Dole. (2008) A study of the pharmacokinetic interactions of the direct renin inhibitor aliskiren with metformin, pioglitazone and fenofibrate in healthy subjects. Current Medical Research and Opinion 24:8, pages 2313-2326.
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Articles from other publishers (16)

Dhiraj M. Rathod, Keyur R. Patel, Hiren N. Mistri, Arvind G. Jangid, Pranav S. Shrivastav & Mallika Sanyal. (2017) Simultaneous analysis of allopurinol and oxypurinol using a validated liquid chromatography–tandem mass spectrometry method in human plasma. Journal of Pharmaceutical Analysis 7:1, pages 56-62.
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Juan Villa, Alejandra Cano, David Franco, Mauricio Monsalve, Jaime Hincapié & Pedro Amariles. (2014) Relevancia clínica de las interacciones medicamentosas entre antiinflamatorios no esteroideos y antihipertensivos. Atención Primaria 46:9, pages 464-474.
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Xia Liu, Xiao-Jia Ni, De-Wei Shang, Ming Zhang, Jin-Qing Hu, Chang Qiu, Fu-Tian Luo & Yu-Guan Wen. (2013) Determination of allopurinol and oxypurinol in human plasma and urine by liquid chromatography-tandem mass spectrometry. Journal of Chromatography B 941, pages 10-16.
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Vinayender Adireddy, Nageswara Rao Pilli, Venkata Ramu Derangula, Shobha Rani Satla, Chinna Veera Badraiah Ganguri & Venkateswarlu Ponneri. (2013) Liquid chromatography–tandem mass spectrometric assay for aliskiren, a novel renin inhibitor in micro‐volumes of human plasma: a pharmacokinetic application in healthy South Indian male subjects. Biomedical Chromatography 27:8, pages 1062-1069.
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Zeynep Aydoğmuş. (2012) Spectrofluorimetric determination of aliskiren in dosage forms and urine. Luminescence 27:6, pages 489-494.
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Luca Bonanni & Michele Dalla Vestra. (2012) Oral renin inhibitors in clinical practice: a perspective review. Therapeutic Advances in Chronic Disease 3:4, pages 173-181.
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Addison A. Taylor & James L. Pool. (2012) Clinical Role of Direct Renin Inhibition in Hypertension. American Journal of Therapeutics 19:3, pages 204-210.
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Azhar Rashikh, Shibli Jameel Ahmad, Krishna Kolappa Pillai & Abul Kalam Najmi. (2012) Aliskiren as a novel therapeutic agent for hypertension and cardio-renal diseases. Journal of Pharmacy and Pharmacology 64:4, pages 470-481.
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Zeynep Aydoğmuş, Ferhat Sarı & Sevgi Tatar Ulu. (2011) Spectrofluorimetric Determination of Aliskiren in Tablets and Spiked Human Plasma through Derivatization with Dansyl Chloride. Journal of Fluorescence 22:2, pages 549-556.
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Venkateswar Jarugula, Ching‐Ming Yeh, Dan Howard, Christopher Bush, Deborah L. Keefe & William P. Dole. (2013) Influence of Body Weight and Gender on the Pharmacokinetics, Pharmacodynamics, and Antihypertensive Efficacy of Aliskiren. The Journal of Clinical Pharmacology 50:12, pages 1358-1366.
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Sean T. Duggan, Claudine M. Chwieduk & Monique P. Curran. (2010) Aliskiren. Drugs 70:15, pages 2011-2049.
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Zafar H Israili, Manuel Velasco & Valmore Bermúdez. (2010) Direct Renin Inhibitors as Antihypertensive Agents. American Journal of Therapeutics 17:3, pages 237-254.
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Graziano Riccioni, Nicola Vitulano, Nicolantonio D’Orazio & Fulvio Bellocci. (2009) Aliskiren, the first approved renin inhibitor: Clinical application and safety in the treatment of hypertension. Advances in Therapy 26:7, pages 700-710.
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. (2009) Current World Literature. Current Opinion in Endocrinology, Diabetes & Obesity 16:3, pages 260-277.
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Cynthia A. Sanoski. (2012) Aliskiren: An Oral Direct Renin Inhibitor for the Treatment of Hypertension. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 29:2, pages 193-212.
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Sujata Vaidyanathan, Venkateswar Jarugula, Hans Armin Dieterich, Dan Howard & William P Dole. (2008) Clinical Pharmacokinetics and Pharmacodynamics of Aliskiren. Clinical Pharmacokinetics 47:8, pages 515-531.
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