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Review

Use of topical corticosteroids and topical calcineurin inhibitors for the treatment of atopic dermatitis in thin and sensitive skin areas

Pages 985-994 | Accepted 18 Jan 2008, Published online: 18 Feb 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Alexander N. Howell, Rima I. Ghamrawi, Lindsay C. Strowd & Steven R. Feldman. (2020) Pharmacological management of atopic dermatitis in the elderly. Expert Opinion on Pharmacotherapy 21:7, pages 761-771.
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Jean-Marie Lachapelle, Ana Gimenez-Arnau, Martin Metz, Jill Peters & Ehrhardt Proksch. (2018) Best practices, new perspectives and the perfect emollient: optimizing the management of contact dermatitis. Journal of Dermatological Treatment 29:3, pages 241-251.
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Michael Sticherling. (2011) Update on the use of topical calcineurin inhibitors in cutaneous lupus erythematosus. Biologics: Targets and Therapy 5, pages 21-31.
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Christos E Lampropoulos & David P D’Cruz. (2010) Topical calcineurin inhibitors in systemic lupus erythematosus. Therapeutics and Clinical Risk Management 6, pages 95-101.
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Eric L. Simpson. (2010) Atopic dermatitis: a review of topical treatment options. Current Medical Research and Opinion 26:3, pages 633-640.
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Elaine C. Siegfried, Eric L. Simpson, Michael J. Cork, Peter D. Arkwright, Lara Wine Lee, Zhen Chen, Randy Prescilla, Ashish Bansal, Noah A. Levit & Ainara Rodríguez Marco. (2023) Dupilumab Treatment Leads to Rapid and Consistent Improvement of Atopic Dermatitis in All Anatomical Regions in Patients Aged 6 Months to 5 Years. Dermatology and Therapy.
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Aneta Kalvodová, Kristýna Dvořáková, Eliška Petrová, Bozena B. Michniak-Kohn & Jarmila Zbytovská. (2023) The Contest of Nanoparticles: Searching for the Most Effective Topical Delivery of Corticosteroids. Pharmaceutics 15:2, pages 513.
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Theodora T. Mautz, Jill M. Krapf & Andrew T. Goldstein. (2022) Topical Corticosteroids in the Treatment of Vulvar Lichen Sclerosus: A Review of Pharmacokinetics and Recommended Dosing Frequencies. Sexual Medicine Reviews 10:1, pages 42-52.
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Andrew Blauvelt, Marjolein de Bruin-Weller, Eric L. Simpson, Zhen Chen, Annie Zhang & Brad Shumel. (2021) Dupilumab with Topical Corticosteroids Provides Rapid and Sustained Improvement in Adults with Moderate-to-Severe Atopic Dermatitis Across Anatomic Regions Over 52 Weeks. Dermatology and Therapy 12:1, pages 223-231.
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T. Luger, A.S. Paller, A.D. Irvine, R. Sidbury, L.F. Eichenfield, T. Werfel & T. Bieber. (2021) Topical therapy of atopic dermatitis with a focus on pimecrolimus. Journal of the European Academy of Dermatology and Venereology 35:7, pages 1505-1518.
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David Luk, Kam Lun Ellis Hon, Maria Victoria C. Dizon, Kin-Fon Leong, Yong-Kwang Tay, Mark Jean-Aan Koh, Nisha Suyien Chandran, Siriwan Wananukul, Susheera Chatproedprai & Thomas Luger. (2020) Practical Recommendations for the Topical Treatment of Atopic Dermatitis in South and East Asia. Dermatology and Therapy 11:1, pages 275-291.
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Kelly M. Cordoro & Anita N. Haggstrom. 2021. Comprehensive Dermatologic Drug Therapy. Comprehensive Dermatologic Drug Therapy 767 776.e3 .
Fabiana Superti. (2020) Lactoferrin from Bovine Milk: A Protective Companion for Life. Nutrients 12:9, pages 2562.
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Т. Люгер, Л. Раеве, К. Гельметти, Т. Какуру, А. Катсару, Д. Ламберт, М. Моррен, А. Оранье, М. Рюэр, С. Сердароглу, А. Торрело & Т. Верфель. (2020) Recommendations for pimecrolimus 1% cream in the treatment of mild-to-moderate atopic dermatitis: from medical needs. Педиатрия. Восточная Европа:1, pages 74-91.
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Lea Solman & Mary Glover. 2019. Harper's Textbook of Pediatric Dermatology. Harper's Textbook of Pediatric Dermatology 253 264 .
Matthew Ladda, Vijay Sandhu, Arvin Ighani & Jensen Yeung. (2019) Off-label Uses of Topical Pimecrolimus. Journal of Cutaneous Medicine and Surgery 23:4, pages 442-448.
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A. Blauvelt, D. Rosmarin, T. Bieber, E.L. Simpson, J. Bagel, M. Worm, M. Deleuran, N. Katoh, M. Kawashima, B. Shumel, Z. Chen, A.B. Rossi, T. Hultsch & M. Ardeleanu. (2019) Improvement of atopic dermatitis with dupilumab occurs equally well across different anatomical regions: data from phase III clinical trials . British Journal of Dermatology 181:1, pages 196-197.
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Jong-Hwa Kim, Kiyoung Kim, Rungravee Kanjanasuntree & Wonyong Kim. (2019) Kazachstania turicensis CAU Y1706 ameliorates atopic dermatitis by regulation of the gut–skin axis. Journal of Dairy Science 102:4, pages 2854-2862.
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Wenyu Jin, Wei Huang, Liqing Chen, Mingji Jin, Qiming Wang, Zhonggao Gao & Zhehu Jin. (2018) Topical Application of JAK1/JAK2 Inhibitor Momelotinib Exhibits Significant Anti-Inflammatory Responses in DNCB-Induced Atopic Dermatitis Model Mice. International Journal of Molecular Sciences 19:12, pages 3973.
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Robert Bissonnette, Lakshmi S. Vasist, Jonathan N. Bullman, Therese Collingwood, Geng Chen & Tomoko Maeda-Chubachi. (2018) Systemic Pharmacokinetics, Safety, and Preliminary Efficacy of Topical AhR Agonist Tapinarof: Results of a Phase 1 Study. Clinical Pharmacology in Drug Development 7:5, pages 524-531.
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Y. R. Kim, H. I. Cheon, L. Misery, C. Taieb & Y. W. Lee. (2018) Sensitive skin in Korean population: An epidemiological approach. Skin Research and Technology 24:2, pages 229-234.
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Jiali Zhong, Zhihong Liu, Xinxin Zhou & Jun Xu. (2017) Synergic Anti-Pruritus Mechanisms of Action for the Radix Sophorae Flavescentis and Fructus Cnidii Herbal Pair. Molecules 22:9, pages 1465.
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Max E. Adrichem, Markus V. Starink, Ester M. M. van Leeuwen, Christine Kramer, Ivo N. van Schaik & Filip Eftimov. (2017) Drug-induced cutaneous lupus erythematosus after immunoglobulin treatment in chronic inflammatory demyelinating polyneuropathy: a case series. Journal of the Peripheral Nervous System 22:3, pages 213-218.
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Zahid Hussain, Hnin Ei Thu, Ahmad Nazrun Shuid, Prashant Kesharwani, Shahzeb Khan & Fahad Hussain. (2017) Phytotherapeutic potential of natural herbal medicines for the treatment of mild-to-severe atopic dermatitis: A review of human clinical studies. Biomedicine & Pharmacotherapy 93, pages 596-608.
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Tamara Cuk Radovic, Kresimir Kostovic, Romana Ceovic & Zrinka Bukvic Mokos. (2017) Topical Calcineurin Inhibitors and Malignancy Risk. International Journal of Cancer Management 10:4.
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Nicholas K. Mollanazar, Peter K. Smith & Gil Yosipovitch. (2015) Mediators of Chronic Pruritus in Atopic Dermatitis: Getting the Itch Out?. Clinical Reviews in Allergy & Immunology 51:3, pages 263-292.
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Mei Shao, Zahid Hussain, Hnin Ei Thu, Shahzeb Khan, Haliza Katas, Tarek A. Ahmed, Minaketan Tripathy, Jing Leng, Hua-Li Qin & Syed Nasir Abbas Bukhari. (2016) Drug nanocarrier, the future of atopic diseases: Advanced drug delivery systems and smart management of disease. Colloids and Surfaces B: Biointerfaces 147, pages 475-491.
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Lee T. Zane, Matilda H. Hughes & Sepehr Shakib. (2016) Tolerability of Crisaborole Ointment for Application on Sensitive Skin Areas: A Randomized, Double-Blind, Vehicle-Controlled Study in Healthy Volunteers. American Journal of Clinical Dermatology 17:5, pages 519-526.
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Osamu Nemoto, Nobukazu Hayashi, Yasumi Kitahara, Masutaka Furue, Seiichiro Hojo, Maiko Nomoto & Satoshi Shima. (2015) Effect of topical phosphodiesterase 4 inhibitor E6005 on Japanese children with atopic dermatitis: Results from a randomized, vehicle‐controlled exploratory trial. The Journal of Dermatology 43:8, pages 881-887.
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Lawrence F. Eichenfield, Wynnis L. Tom, Timothy G. Berger, Alfons Krol, Amy S. Paller, Kathryn Schwarzenberger, James N. Bergman, Sarah L. Chamlin, David E. Cohen, Kevin D. Cooper, Kelly M. Cordoro, Dawn M. Davis, Steven R. Feldman, Jon M. Hanifin, David J. Margolis, Robert A. Silverman, Eric L. Simpson, Hywel C. Williams, Craig A. Elmets, Julie Block, Christopher G. Harrod, Wendy Smith Begolka & Robert Sidbury. (2014) Guidelines of care for the management of atopic dermatitis. Journal of the American Academy of Dermatology 71:1, pages 116-132.
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Ana Rita Rodrigues-Barata & Luis Conde-Salazar Gómez. (2013) Piel sensible. Piel 28:9, pages 520-530.
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Chang-Hyun Kim, Kyung Ah Cheong & Ai-Young Lee. (2013) 850nm light-emitting-diode phototherapy plus low-dose tacrolimus (FK-506) as combination therapy in the treatment of dermatophagoides farinae-induced atopic dermatitis-like skin lesions in NC/Nga mice. Journal of Dermatological Science 72:2, pages 142-148.
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Warner W. Carr. (2013) Topical Calcineurin Inhibitors for Atopic Dermatitis: Review and Treatment Recommendations. Pediatric Drugs 15:4, pages 303-310.
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Naoto Ishii, Manabu Shirato, Hisashi Wakita, Kazuki Miyazaki, Yasutaka Takase, Osamu Asano, Kazutomi Kusano, Eiichi Yamamoto, Chiharu Inoue & Ieharu Hishinuma. (2013) Antipruritic Effect of the Topical Phosphodiesterase 4 Inhibitor E6005 Ameliorates Skin Lesions in a Mouse Atopic Dermatitis Model. Journal of Pharmacology and Experimental Therapeutics 346:1, pages 105-112.
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Chang-Hyun Kim, Yun-Seok Choi, Kyung Ah. Cheong & Ai-Young Lee. (2013) Mechanism underlying the effect of combined therapy using glucosamine and low-dose cyclosporine A on the development of atopic dermatitis-like skin lesions in NC/Nga mice. International Immunopharmacology 15:2, pages 424-432.
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Ji-Eun SungMoon-Hwa KwakJi-Eun KimYoung-Ju LeeRo-Ui KimEun-Ah KimGa-Young LeeDong-Seob KimDae-Youn Hwang. (2013) Therapeutic effects of fermented soycrud on phenotypes of atopic dermatitis induced by phthalic anhydride. Laboratory Animal Research 29:2, pages 103.
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Brandie T. Styron & Anita N. Haggstrom. 2013. Comprehensive Dermatologic Drug Therapy. Comprehensive Dermatologic Drug Therapy 778 786.e2 .
Erwin Suys. (2012) Randomized study of topical tacrolimus ointment as possible treatment for resistant idiopathic pruritus ani. Journal of the American Academy of Dermatology 66:2, pages 327-328.
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M.-S. Doutre & M. Beylot-Barry. (2011) About some red faces. Annales de Dermatologie et de Vénéréologie 138, pages S201-S206.
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J. Escalas-Taberner, E. González-Guerra & A. Guerra-Tapia. (2011) Sensitive Skin: A Complex Syndrome. Actas Dermo-Sifiliográficas (English Edition) 102:8, pages 563-571.
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J. Escalas-Taberner, E. González-Guerra & A. Guerra-Tapia. (2011) La piel sensible: un síndrome complejo. Actas Dermo-Sifiliográficas 102:8, pages 563-571.
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M.-S. Doutre & M. Beylot-Barry. (2011) À propos de quelques visages rouges. Annales de Dermatologie et de Vénéréologie 138, pages S148-S153.
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S. M. Breathnach. 2010. Rook's Textbook of Dermatology. Rook's Textbook of Dermatology 1 177 .
Lily P.H. Yang & Monique P. Curran. (2009) Topical Pimecrolimus. Pediatric Drugs 11:6, pages 407-426.
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Miklós Sárdy, Thomas Ruzicka & Annegret Kuhn. (2008) Topical calcineurin inhibitors in cutaneous lupus erythematosus. Archives of Dermatological Research 301:1, pages 93-98.
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