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Original Article

In vitro disintegration and dissolution studies of once-weekly copies of alendronate sodium tablets (70  mg) and in vivo implications

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Pages 1137-1145 | Accepted 20 Mar 2008, Published online: 20 Feb 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Pauline Siew Mei Lai, Siew Siang Chua, Yah Huei Chong & Siew Pheng Chan. (2012) The effect of mandatory generic substitution on the safety of alendronate and patients’ adherence. Current Medical Research and Opinion 28:8, pages 1347-1355.
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A.D. Walker & J.D. Adachi. (2011) In vitro disintegration studies of weekly generic and branded risedronate sodium formulations available in Canada. Current Medical Research and Opinion 27:9, pages 1749-1754.
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Michael Pazianas, Cyrus Cooper, F Hal Ebetino & R Graham G Russell. (2010) Long-term treatment with bisphosphonates and their safety in postmenopausal osteoporosis. Therapeutics and Clinical Risk Management 6, pages 325-343.
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Richard J. Dansereau, Debbie J. Crail & Alan C. Perkins. (2009) In vitro disintegration studies of weekly generic alendronate sodium tablets (70 mg) available in the US. Current Medical Research and Opinion 25:2, pages 449-452.
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Articles from other publishers (11)

Deborah T. Gold. 2021. Marcus and Feldman's Osteoporosis. Marcus and Feldman's Osteoporosis 1695 1707 .
Wojciech P. Olszynski, Jonathan D. Adachi & K. Shawn Davison. (2014) Differences in In Vitro Disintegration Time among Canadian Brand and Generic Bisphosphonates . Journal of Osteoporosis 2014, pages 1-6.
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Jacques P Brown, Kenneth S Davison, Wojciech P Olszynski, Karen A Beattie & Jonathan D Adachi. (2013) A critical review of brand and generic alendronate for the treatment of osteoporosis. SpringerPlus 2:1.
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Joop P. W. van den Bergh, Marian E. Bouts, Eveline van der Veer, Robert Y. van der Velde, Marcel J. W. Janssen, Piet P. Geusens, Bjorn Winkens, Nico J. J. Oldenhof & Tineke A. C. M. van Geel. (2013) Comparing Tolerability and Efficacy of Generic versus Brand Alendronate: A Randomized Clinical Study in Postmenopausal Women with a Recent Fracture. PLoS ONE 8:10, pages e78153.
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Caterina Musolino & Alessandro Allegra. 2013. Pathobiology of Cancer Regimen-Related Toxicities. Pathobiology of Cancer Regimen-Related Toxicities 249 282 .
Claudia Gómez Acotto, Carlos Antonelli, Damien Flynn, Dennis McDaid & Emilio J. A. Roldán. (2012) Upper Gastrointestinal Tract Transit Times of Tablet and Drinkable Solution Formulations of Alendronate: A Bioequivalence and a Quantitative, Randomized Study using Video Deglutition. Calcified Tissue International 91:5, pages 325-334.
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J. A. Kanis, J.-Y. Reginster, J.-M. Kaufman, J.-D. Ringe, J. D. Adachi, M. Hiligsmann, R. Rizzoli & C. Cooper. (2011) A reappraisal of generic bisphosphonates in osteoporosis. Osteoporosis International 23:1, pages 213-221.
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Serge Cremers & Socrates Papapoulos. (2011) Pharmacology of bisphosphonates. Bone 49:1, pages 42-49.
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Stuart H. Ralston, Tzuyung D. Kou, Bettina Wick-Urban, Michael Steinbuch & Tahir Masud. (2010) Risk of Upper Gastrointestinal Tract Events in Risedronate Users Switched to Alendronate. Calcified Tissue International 87:4, pages 298-304.
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Johann D. Ringe & Gerd Möller. (2009) Differences in persistence, safety and efficacy of generic and original branded once weekly bisphosphonates in patients with postmenopausal osteoporosis: 1-year results of a retrospective patient chart review analysis. Rheumatology International 30:2, pages 213-221.
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Guenther Lamprecht. (2009) In vitro Determination of the Release of Alendronic Acid from Alendronate Tablets of Different Brands During Deglutition. Journal of Pharmaceutical Sciences 98:10, pages 3575-3581.
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