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Current Medical Research and Opinion Volume 25, 2009 - Issue 4
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Review

Albinterferon alfa-2b, a novel fusion protein of human albumin and human interferon alfa-2b, for chronic hepatitis C

Vinod K. Rustgi Georgetown University Medical Center, Fairfax, VA, USACorrespondence[email protected]
Pages 991-1002 | Accepted 27 Jan 2009, Published online: 11 Mar 2009

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Darrell Sleep. (2015) Albumin and its application in drug delivery. Expert Opinion on Drug Delivery 12:5, pages 793-812.
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Carolina Scagnolari & Guido Antonelli. (2013) Antiviral activity of the interferon α family: biological and pharmacological aspects of the treatment of chronic hepatitis C. Expert Opinion on Biological Therapy 13:5, pages 693-711.
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Cecilia Sgadari, Ilaria Bacigalupo, Giovanni Barillari & Barbara Ensoli. (2011) Pharmacological management of Kaposi's sarcoma. Expert Opinion on Pharmacotherapy 12:11, pages 1669-1690.
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Elena Neumann, Eva Frei, Dorothee Funk, Matthias D Becker, Hans-Hermann Schrenk, Ulf Müller-Ladner & Christoph Fiehn. (2010) Native albumin for targeted drug delivery. Expert Opinion on Drug Delivery 7:8, pages 915-925.
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Rivka Yatuv, Micah Robinson, Inbal Dayan & Moshe Baru. (2010) Enhancement of the efficacy of therapeutic proteins by formulation with PEGylated liposomes; a case of FVIII, FVIIa and G-CSF. Expert Opinion on Drug Delivery 7:2, pages 187-201.
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Articles from other publishers (30)

Bruce A. Molitoris, Ruben M. Sandoval, Shiv Pratap S. Yadav & Mark C. Wagner. (2022) Albumin uptake and processing by the proximal tubule: physiological, pathological, and therapeutic implications. Physiological Reviews 102:4, pages 1625-1667.
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Ivan S. Pires, Paula T. Hammond & Darrell J. Irvine. (2021) Engineering Strategies for Immunomodulatory Cytokine Therapies: Challenges and Clinical Progress. Advanced Therapeutics 4:8.
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Andreas Geissner, Lars Baumann, Thomas J. Morley, Andrew K. O. Wong, Lyann Sim, Jamie R. Rich, Pauline P. L. So, Edie M. Dullaghan, Etienne Lessard, Umar Iqbal, Maria Moreno, Warren W. Wakarchuk & Stephen G. Withers. (2021) 7-Fluorosialyl Glycosides Are Hydrolysis Resistant but Readily Assembled by Sialyltransferases Providing Easy Access to More Metabolically Stable Glycoproteins. ACS Central Science 7:2, pages 345-354.
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Naveen Kumar, Shalini Sharma, Ram Kumar, Bhupendra N. Tripathi, Sanjay Barua, Hinh Ly & Barry T. Rouse. (2020) Host-Directed Antiviral Therapy. Clinical Microbiology Reviews 33:3.
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Fatima Ahsan, Qurratulann Afza Gardner, Naeem Rashid, Greg J. Towers & Muhammad Akhtar. (2018) Preventing the N-terminal processing of human interferon α-2b and its chimeric derivatives expressed in Escherichia coli. Bioorganic Chemistry 76, pages 294-302.
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Jeonghoon Sun & Mark Michaels. 2018. Challenges in Protein Product Development. Challenges in Protein Product Development 527 544 .
Yanhua Ding, Jinfeng Lou, Hong Chen, Xiaojiao Li, Min Wu, Cuiyun Li, Jingrui Liu, Chengjiao Liu, Qingmei Li, Hong Zhang & Junqi Niu. (2016) Tolerability, pharmacokinetics and antiviral activity of rHSA/IFNα2a for the treatment of chronic hepatitis B infection. British Journal of Clinical Pharmacology 83:5, pages 1056-1071.
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Toru Maruyama, Victor Tuan Giam Chuang & Masaki Otagiri. 2016. Albumin in Medicine. Albumin in Medicine 71 89 .
Uli Binder & Arne Skerra. 2015. Biobetters. Biobetters 269 311 .
Angela W. Blake‐Haskins, Yen‐Huei Lin, Zhuchun Wu, Melissa D. Perkins & Thomas M. Spitznagel. 2014. Biophysical Methods for Biotherapeutics. Biophysical Methods for Biotherapeutics 93 123 .
Wei Liu, Jianjun Tan, Mohammadreza Mohammadzad Mehryar, Zhiping Teng & Yi Zeng. (2014) Peptide HIV fusion inhibitors: modifications and conjugations. Med. Chem. Commun. 5:10, pages 1472-1482.
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Michelle R. Joshi, Nianhuan Yao, Kenneth A. Myers & Zhiyu Li. (2013) Human Serum Albumin and p53-Activating Peptide Fusion Protein Is Able to Promote Apoptosis and Deliver Fatty Acid-Modified Molecules. PLoS ONE 8:11, pages e80926.
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Fumiyoshi Yamashita & Mitsuru Hashida. (2013) Pharmacokinetic considerations for targeted drug delivery. Advanced Drug Delivery Reviews 65:1, pages 139-147.
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Kwangwon HongKwangjun OhSiyoung LeeJaewoo HongJida ChoiAreum KwakDongjun KangEunsom KimSeunghyun JoHyunjhung JhunSoohyun Kim. (2012) Recombinant Fc-IL-18BPc Isoform Inhibits IL-18-Induced Cytokine Production. Hybridoma 31:2, pages 99-104.
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Hubert J. Metzner, Thomas Weimer & Stefan Schulte. 2012. Therapeutic Proteins. Therapeutic Proteins 223 247 .
Roland E. Kontermann. 2012. Therapeutic Proteins. Therapeutic Proteins 1 21 .
William Kemp & Stuart K. Roberts. 2012. Chronic Hepatitis C Virus. Chronic Hepatitis C Virus 115 130 .
Andrew V. StachulskiChandrakala PidathalaEleanor C. RowRaman SharmaNeil G. BerryAlexandre S. LawrensonShelley L. MooresMazhar IqbalJoanne BentleySarah A. AllmanGeoffrey EdwardsAlison HelmJennifer HellierBrent E. Korba, J. Edward Semple & Jean-Francois Rossignol. (2011) Thiazolides as Novel Antiviral Agents. 2. Inhibition of Hepatitis C Virus Replication. Journal of Medicinal Chemistry 54:24, pages 8670-8680.
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Roland E Kontermann. (2011) Strategies for extended serum half-life of protein therapeutics. Current Opinion in Biotechnology 22:6, pages 868-876.
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Jianmin Li, Bing Li, Jun Zhang, Lihua Hou, Changming Yu, Ling Fu, Xiaohong Song, Ting Yu, Jinglong Zhang, Jun Ren, Chun’e Xu & Wei Chen. (2011) Preparation of CHO cell-derived rhIFN-ω-Fc with improved pharmacokinetics. Antiviral Research 89:3, pages 199-203.
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Denise B. Serra, Haiying Sun, Sylwia Karwowska, Jens Praestgaard, Atef Halabi & Daniel S. Stein. (2011) Single-Dose Pharmacokinetics, Safety, and Tolerability of Albinterferon Alfa-2b in Subjects with End-Stage Renal Disease on Hemodialysis Compared to Those in Matched Healthy Volunteers. Antimicrobial Agents and Chemotherapy 55:2, pages 473-477.
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Jarrod Bailey. (2010) An Assessment of the Use of Chimpanzees in Hepatitis C Research Past, Present and Future: 1. Validity of the Chimpanzee Model. Alternatives to Laboratory Animals 38:5, pages 387-418.
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Tatsuo Kanda, Fumio Imazeki & Osamu Yokosuka. (2010) New antiviral therapies for chronic hepatitis C. Hepatology International 4:3, pages 548-561.
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Hong-Hwa Lee, Min-Jung Lee, Sun-Ju Heo & Hong-Kee Sah. (2010) Parenteral Formulations Based on Albumin Particulate Technology. Journal of Pharmaceutical Investigation 40:spc, pages 83-95.
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Graham R. Foster. 2010. Clinical Dilemmas in Viral Liver Disease. Clinical Dilemmas in Viral Liver Disease 236 238 .
Leen Delang, Lotte Coelmont & Johan Neyts. (2010) Antiviral Therapy for Hepatitis C Virus: Beyond the Standard of Care. Viruses 2:4, pages 826-866.
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Naoya SakamotoGeorge Y Wu. (2009) Prospects for future therapy of HCV infection. Future Virology 4:5, pages 453-462.
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Kimberly A. Forde & K. Rajender Reddy. (2009) Hepatitis C Virus Infection and Immunomodulatory Therapies. Clinics in Liver Disease 13:3, pages 391-401.
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Naoya Sakamoto & Mamoru Watanabe. (2009) New therapeutic approaches to hepatitis C virus. Journal of Gastroenterology 44:7, pages 643-649.
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