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Original Article

Efficacy and safety of combination therapy with 5% lidocaine medicated plaster and pregabalin in post-herpetic neuralgia and diabetic polyneuropathy

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Pages 1677-1687 | Accepted 05 May 2009, Published online: 29 May 2009

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Read on this site (16)

Kalliopi Pafili & Nikolaos Papanas. (2021) Considerations for single- versus multiple-drug pharmacotherapy in the management of painful diabetic neuropathy. Expert Opinion on Pharmacotherapy 22:16, pages 2267-2280.
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Jeff Gudin & Sri Nalamachu. (2020) Utility of lidocaine as a topical analgesic and improvements in patch delivery systems. Postgraduate Medicine 132:1, pages 28-36.
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Mariana Palladini, Irmgard Boesl, Simone Koenig, Bettina Buchheister & Nadine Attal. (2019) Lidocaine medicated plaster, an additional potential treatment option for localized post-surgical neuropathic pain: efficacy and safety results of a randomized, placebo-controlled trial. Current Medical Research and Opinion 35:5, pages 757-766.
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John Schutzer-Weissmann & Paul Farquhar-Smith. (2017) Post-herpetic neuralgia – a review of current management and future directions. Expert Opinion on Pharmacotherapy 18:16, pages 1739-1750.
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Oscar A de León-Casasola & Victor Mayoral. (2016) The topical 5% lidocaine medicated plaster in localized neuropathic pain: a reappraisal of the clinical evidence. Journal of Pain Research 9, pages 67-79.
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Jana Sawynok & Celia Zinger. (2016) Topical amitriptyline and ketamine for post-herpetic neuralgia and other forms of neuropathic pain. Expert Opinion on Pharmacotherapy 17:4, pages 601-609.
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Mark S. Juhn, Bruce Parsons, Roxanna Varvara & Alesia Sadosky. (2015) Pregabalin for painful diabetic peripheral neuropathy: strategies for dosing, monotherapy vs. combination therapy, treatment-refractory patients, and adverse events. Current Medical Research and Opinion 31:5, pages 1017-1026.
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Aaron I Vinik & Carolina M Casellini. (2013) Guidelines in the management of diabetic nerve pain: clinical utility of pregabalin. Diabetes, Metabolic Syndrome and Obesity 6, pages 57-78.
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R. Norman Harden, Alan David Kaye, Thomas Kintanar & Charles E. Argoff. (2013) Evidence-based Guidance for the Management of Postherpetic Neuralgia in Primary Care. Postgraduate Medicine 125:4, pages 191-202.
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Gérard Mick & Gerardo Correa-Illanes. (2012) Topical pain management with the 5% lidocaine medicated plaster – a review. Current Medical Research and Opinion 28:6, pages 937-951.
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Cory Toth. (2012) Drug safety evaluation of pregabalin . Expert Opinion on Drug Safety 11:3, pages 487-502.
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Burkhard Gustorff, David Hauer, Johannes Thaler, Astrid Seis & Julia Draxler. (2011) Antihyperalgesic efficacy of 5% lidocaine medicated plaster in capsaicin and sunburn pain models – two randomized, double-blinded, placebo-controlled crossover trials in healthy volunteers. Expert Opinion on Pharmacotherapy 12:18, pages 2781-2790.
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Stefanie Rehm, Andreas Binder & Ralf Baron. (2010) Post-herpetic neuralgia: 5% lidocaine medicated plaster, pregabalin, or a combination of both? A randomized, open, clinical effectiveness study. Current Medical Research and Opinion 26:7, pages 1607-1619.
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Zorba Paster & Charlene M. Morris. (2010) Treatment of the Localized Pain of Postherpetic Neuralgia. Postgraduate Medicine 122:1, pages 91-107.
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Guy Hans, Ellen Joukes, Johanna Verhulst & Marcel Vercauteren. (2009) Management of neuropathic pain after surgical and non-surgical trauma with lidocaine 5% patches: study of 40 consecutive cases. Current Medical Research and Opinion 25:11, pages 2737-2743.
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. 2013. Neuropathic Pain. Neuropathic Pain 217 314 .
Honorio T. Benzon, Mark C. Kendall, Jeffrey A. Katz, Hubert A. Benzon, Khalid Malik, Paul Cox, Kathryn Dean & Michael J. Avram. (2013) Prescription Patterns of Pain Medicine Physicians. Pain Practice 13:6, pages 440-450.
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John S Edelsberg, Claudia LordGerry Oster. (2011) Systematic Review and Meta-Analysis of Efficacy, Safety, and Tolerability Data from Randomized Controlled Trials of Drugs Used to Treat Postherpetic Neuralgia. Annals of Pharmacotherapy 45:12, pages 1483-1490.
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R. F. Wolff, M. M. Bala, M. Westwood, A. G. Kessels & J. Kleijnen. (2011) 5% lidocaine-medicated plaster vs other relevant interventions and placebo for post-herpetic neuralgia (PHN): a systematic review. Acta Neurologica Scandinavica 123:5, pages 295-309.
Crossref
Ralf Baron, Andreas Binder & Gunnar Wasner. (2010) Neuropathic pain: diagnosis, pathophysiological mechanisms, and treatment. The Lancet Neurology 9:8, pages 807-819.
Crossref
R. Baron & F. Mahn. (2010) Topische Therapieformen bei peripheren neuropathischen SchmerzenTypes of topical treatment for peripheral neuropathic pain. Der Schmerz 24:4, pages 317-325.
Crossref
Mitra Tavakoli, Omar Asghar, Uazman Alam, Ioannis N. Petropoulos, Hassan Fadavi & Rayaz A. Malik. (2010) Review: Novel insights on diagnosis, cause and treatment of diabetic neuropathy: focus on painful diabetic neuropathy. Therapeutic Advances in Endocrinology and Metabolism 1:2, pages 69-88.
Crossref
Sushma Srikrishna, Dudley Robinson & Linda Cardozo. (2009) Validation of the Patient Global Impression of Improvement (PGI-I) for urogenital prolapse. International Urogynecology Journal 21:5, pages 523-528.
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Robert H. Dworkin, Alec B. O'Connor, Joseph Audette, Ralf Baron, Geoffrey K. Gourlay, Maija L. Haanpää, Joel L. Kent, Elliot J. Krane, Alyssa A. LeBel, Robert M. Levy, Sean C. Mackey, John Mayer, Christine Miaskowski, Srinivasa N. Raja, Andrew S.C. Rice, Kenneth E. Schmader, Brett Stacey, Steven Stanos, Rolf-Detlef Treede, Dennis C. Turk, Gary A. Walco & Christopher D. Wells. (2010) Recommendations for the Pharmacological Management of Neuropathic Pain: An Overview and Literature Update. Mayo Clinic Proceedings 85:3, pages S3-S14.
Crossref
Mark Ritchie, Hiltrud Liedgens & Mark Nuijten. (2010) Cost Effectiveness of a Lidocaine 5% Medicated Plaster Compared with Pregabalin for the Treatment of Postherpetic Neuralgia in the UK. Clinical Drug Investigation 30:2, pages 71-87.
Crossref
. (2010) Current awareness: Pharmacoepidemiology and drug safety. Pharmacoepidemiology and Drug Safety 19:2.
Crossref
Steve N. Quessy. (2010) Two-stage enriched enrolment pain trials: A brief review of designs and opportunities for broader application. Pain 148:1, pages 8-13.
Crossref
J.R. González-Escalada, M.J. Rodríguez, M.A. Camba, A. Portolés & R. López. (2009) Recomendaciones para el tratamiento del dolor neuropático. Revista de la Sociedad Española del Dolor 16:8, pages 445-467.
Crossref
Karly P. Garnock-Jones & Gillian M. Keating. (2009) Lidocaine 5% Medicated Plaster. Drugs 69:15, pages 2149-2165.
Crossref
Jee Youn MoonJong Bum ChoiPyung Bok LeeHe Min SonFrancis Sanhgun NamYoung Chul KimSang Chul LeeSang Jin Lee. (2009) An Open-Label Trial of the 5% Lidocaine Patches for the Treatment of Chronic Pain. The Korean Journal of Pain 22:3, pages 216.
Crossref

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