716
Views
44
CrossRef citations to date
0
Altmetric
Original Article

Efficacy and safety of linezolid in methicillin-resistant Staphylococcus aureus (MRSA) complicated skin and soft tissue infection (cSSTI): a meta-analysis

&
Pages 407-421 | Accepted 02 Nov 2009, Published online: 11 Dec 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (9)

Vicente Pintado, Rosario Pazos, Manuel Enrique Jiménez-Mejías, Azucena Rodríguez-Guardado, Beatriz Díaz-Pollán, Carmen Cabellos, Juan Manuel García-Lechuz, Jaime Lora-Tamayo, Pere Domingo, Elena Muñez, Diego Domingo, Fernando González-Romo, José Antonio Lepe-Jiménez, Carlos Rodríguez-Lucas, Eulalia Valencia, Iván Pelegrín, Fernando Chaves, Virginia Pomar, Antonio Ramos, Teresa Alarcón & Elisa Pérez-Cecilia. (2020) Linezolid for therapy of Staphylococcus aureus meningitis: a cohort study of 26 patients. Infectious Diseases 52:11, pages 808-815.
Read now
Hoe Nam Leong, Asok Kurup, Mak Yong Tan, Andrea Lay Hoon Kwa, Kui Hin Liau & Mark H Wilcox. (2018) Management of complicated skin and soft tissue infections with a special focus on the role of newer antibiotics. Infection and Drug Resistance 11, pages 1259-1274.
Read now
H. Thom, J. C. Thompson, D. A. Scott, N. Halfpenny, K. Sulham & G. R. Corey. (2015) Comparative efficacy of antibiotics for the treatment of acute bacterial skin and skin structure infections (ABSSSI): a systematic review and network meta-analysis. Current Medical Research and Opinion 31:8, pages 1539-1551.
Read now
Jennifer M Stephens, Xin Gao, Dipen A Patel, Bram G Verheggen, Ahmed Shelbaya & Seema Haider. (2013) Economic burden of inpatient and outpatient antibiotic treatment for methicillin-resistant Staphylococcus aureus complicated skin and soft-tissue infections: a comparison of linezolid, vancomycin, and daptomycin. ClinicoEconomics and Outcomes Research 5, pages 447-457.
Read now
Mark Bounthavong & Donald I Hsu. (2012) Cost–effectiveness of linezolid in methicillin-resistant Staphylococcus aureus skin and skin structure infections. Expert Review of Pharmacoeconomics & Outcomes Research 12:6, pages 683-698.
Read now
Robert K Flamm, David J Farrell, Rodrigo E Mendes, James E Ross, Helio S Sader & Ronald N Jones. (2012) ZAAPS Program results for 2010: an activity and spectrum analysis of linezolid using clinical isolates from 75 medical centres in 24 countries. Journal of Chemotherapy 24:6, pages 328-337.
Read now
Sally Ager & Kate Gould. (2012) Clinical update on linezolid in the treatment of Gram-positive bacterial infections. Infection and Drug Resistance 5, pages 87-102.
Read now
S. Esposito, M. Bassetti, S. Borre, E. Bouza, M. Dryden, M. Fantoni, I.M. Gould, F. Leoncini, S. Leone, G. Milkovich, D. Natwani, J. Segreti, G. Sganga, S. Unal & M. Venditti. (2011) Diagnosis and management of Skin and Soft-Tissue Infections (SSTI): a Literature Review and Consensus Statement on Behalf of the Italian Society of Infectious Diseases and International Society of Chemotherapy. Journal of Chemotherapy 23:5, pages 251-262.
Read now
J.E. Ross, D.J. Farrell, R.E. Mendes, H.S. Sader & R.N. Jones. (2011) Eight-year (2002-2009) Summary of the Linezolid (Zyvox® Annual Appraisal of potency and Spectrum; ZAAPS) Program in European Countries. Journal of Chemotherapy 23:2, pages 71-76.
Read now

Articles from other publishers (35)

Francesca Sivori, Ilaria Cavallo, Daniela Kovacs, Maria Guembe, Isabella Sperduti, Mauro Truglio, Martina Pasqua, Grazia Prignano, Arianna Mastrofrancesco, Luigi Toma, Fulvia Pimpinelli, Aldo Morrone, Fabrizio Ensoli & Enea Gino Di Domenico. (2022) Role of Extracellular DNA in Dalbavancin Activity against Methicillin-Resistant Staphylococcus aureus (MRSA) Biofilms in Patients with Skin and Soft Tissue Infections. Microbiology Spectrum 10:2.
Crossref
Jingjuan Feng, Feng Xiang, Jian Cheng, Yeli Gou & Jun Li. (2021) Comparative Efficacy and Safety of Vancomycin, Linezolid, Tedizolid, and Daptomycin in Treating Patients with Suspected or Proven Complicated Skin and Soft Tissue Infections: An Updated Network Meta-Analysis. Infectious Diseases and Therapy 10:3, pages 1531-1547.
Crossref
Yamuna Devi Bakthavatchalam, Shoma Vinay Rao, Barney Isaac, Abi Manesh, Senthur Nambi, Subramanian Swaminathan, Vasanth Nagvekar, Vivek Nangia, Peter Victor John & Balaji Veeraraghavan. (2019) A Comparative Assessment of Clinical, Pharmacological and Antimicrobial Profile of Novel Anti-methicillin-resistant Staphylococcus aureus Agent Levonadifloxacin: Therapeutic Role in Nosocomial and Community Infections. Indian Journal of Medical Microbiology 37:4, pages 478-487.
Crossref
Patience Shumba, Srikanth Mairpady Shambat & Nikolai Siemens. (2019) The Role of Streptococcal and Staphylococcal Exotoxins and Proteases in Human Necrotizing Soft Tissue Infections. Toxins 11:6, pages 332.
Crossref
Claire Roger, Jason A. Roberts & Laurent Muller. (2017) Clinical Pharmacokinetics and Pharmacodynamics of Oxazolidinones. Clinical Pharmacokinetics 57:5, pages 559-575.
Crossref
Julian F. Guest, Jaime Esteban, Anton G. Manganelli, Andrea Novelli, Giuliano Rizzardini & Miquel Serra. (2017) Comparative efficacy and safety of antibiotics used to treat acute bacterial skin and skin structure infections: Results of a network meta-analysis. PLOS ONE 12:11, pages e0187792.
Crossref
Jirong Yue, Bi Rong Dong, Ming Yang, Xiaomei Chen, Taixiang Wu & Guan J Liu. (2016) Linezolid versus vancomycin for skin and soft tissue infections. Cochrane Database of Systematic Reviews.
Crossref
Christos Tsoulas & Dilip Nathwani. (2015) Review of meta-analyses of vancomycin compared with new treatments for Gram-positive skin and soft-tissue infections: Are we any clearer?. International Journal of Antimicrobial Agents 46:1, pages 1-7.
Crossref
Philip S. Barie & Samuel E. Wilson. (2015) Impact of Evolving Epidemiology on Treatments for Complicated Skin and Skin Structure Infections: The Surgical Perspective. Journal of the American College of Surgeons 220:1, pages 105-116.e6.
Crossref
Shigeto Oda, Mayuki Aibiki, Toshiaki Ikeda, Hitoshi Imaizumi, Shigeatsu Endo, Ryoichi Ochiai, Joji Kotani, Nobuaki Shime, Osamu Nishida, Takayuki Noguchi, Naoyuki Matsuda & Hiroyuki Hirasawa. (2014) The Japanese guidelines for the management of sepsis. Journal of Intensive Care 2:1.
Crossref
Alpesh N. Amin, Elizabeth A. Cerceo, Steven B. Deitelzweig, James C. Pile, David J. Rosenberg & Bradley M. Sherman. (2014) Hospitalist Perspective on the Treatment of Skin and Soft Tissue Infections. Mayo Clinic Proceedings 89:10, pages 1436-1451.
Crossref
Yun Fei Wang, Hua Fa Que, Yong-Jun Wang & Xue Jun Cui. (2014) Chinese herbal medicines for treating skin and soft-tissue infections. Cochrane Database of Systematic Reviews 2014:7.
Crossref
J. Barberán, J.F. Varona & M.I. Tejeda. (2014) Infecciones por estafilococos. Medicine - Programa de Formación Médica Continuada Acreditado 11:59, pages 3477-3484.
Crossref
Theodor Tirilomis. (2014) Daptomycin and Its Immunomodulatory Effect: Consequences for Antibiotic Treatment of Methicillin-Resistant Staphylococcus aureus Wound Infections after Heart Surgery. Frontiers in Immunology 5.
Crossref
R. A. Seaton, S. Johal, J. E. Coia, N. Reid, S. Cooper & B. L. Jones. (2013) Economic evaluation of treatment for MRSA complicated skin and soft tissue infections in Glasgow hospitals. European Journal of Clinical Microbiology & Infectious Diseases 33:3, pages 305-311.
Crossref
Jirong Yue, Bi Rong Dong, Ming Yang, Xiaomei Chen, Taixiang Wu & Guan J Liu. (2014) Linezolid versus vancomycin for skin and soft tissue infections. Evidence-Based Child Health: A Cochrane Review Journal 9:1, pages 103-166.
Crossref
Sangeetha Thirumazhisi Sachithanandam. (2014) Rising Methicillin-Resistant Staphylococcus aureus Infections in Ear, Nose, and Throat Diseases . Case Reports in Otolaryngology 2014, pages 1-3.
Crossref
Jirong Yue, Bi Rong Dong, Ming Yang, Xiaomei Chen, Taixiang Wu & Guan J Liu. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
Yun Fei Wang, Hua Fa Que, Yong-Jun Wang & Xue Jun Cui. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
Gregory J. Moran, Fredrick M. Abrahamian, Frank LoVecchio & David A. Talan. (2013) Acute Bacterial Skin Infections: Developments Since the 2005 Infectious Diseases Society of America (IDSA) Guidelines. The Journal of Emergency Medicine 44:6, pages e397-e412.
Crossref
S. J. Vandecasteele, A. S. De Vriese & E. Tacconelli. (2012) The pharmacokinetics and pharmacodynamics of vancomycin in clinical practice: evidence and uncertainties. Journal of Antimicrobial Chemotherapy 68:4, pages 743-748.
Crossref
Anna-Bettina Haidich, Dimitrios Pilalas, Despina G. Contopoulos-Ioannidis & John P.A. Ioannidis. (2013) Most meta-analyses of drug interventions have narrow scopes and many focus on specific agents. Journal of Clinical Epidemiology 66:4, pages 371-378.
Crossref
Kurinchi Selvan Gurusamy, Peter Wilson & Brian R Davidson. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
Michèle Bally, Nandini Dendukuri, Alison Sinclair, Stéphane P. Ahern, Michel Poisson & James Brophy. (2012) A network meta-analysis of antibiotics for treatment of hospitalised patients with suspected or proven meticillin-resistant Staphylococcus aureus infection. International Journal of Antimicrobial Agents 40:6, pages 479-495.
Crossref
Ian M. Gould, Michael Z. David, Silvano Esposito, Javier Garau, Gerard Lina, Teresita Mazzei & Georg Peters. (2012) New insights into meticillin-resistant Staphylococcus aureus (MRSA) pathogenesis, treatment and resistance. International Journal of Antimicrobial Agents 39:2, pages 96-104.
Crossref
M. A. Cataldo, E. Tacconelli, E. Grilli, F. Pea & N. Petrosillo. (2011) Continuous versus intermittent infusion of vancomycin for the treatment of Gram-positive infections: systematic review and meta-analysis. Journal of Antimicrobial Chemotherapy 67:1, pages 17-24.
Crossref
Emily C. Tucker & David L. Gordon. 2012. A worldwide yearly survey of new data in adverse drug reactions and interactions. A worldwide yearly survey of new data in adverse drug reactions and interactions 399 425 .
Sebastiaan J. van Hal & David L. Paterson. (2011) New Gram-positive antibiotics. Current Opinion in Infectious Diseases 24:6, pages 515-520.
Crossref
Mark Bounthavong, Amir Zargarzadeh, Donald I. Hsu & David J. Vanness. (2011) Cost-Effectiveness Analysis of Linezolid, Daptomycin, and Vancomycin in Methicillin-Resistant Staphylococcus aureus: Complicated Skin and Skin Structure Infection Using Bayesian Methods for Evidence Synthesis. Value in Health 14:5, pages 631-639.
Crossref
Ronald N. Jones, David J. Farrell & Helio S. Sader. (2011) Comparative activity of linezolid against respiratory tract infection isolates of Staphylococcus aureus: an 11-year report from the SENTRY Antimicrobial Surveillance Program. International Journal of Antimicrobial Agents 37:6, pages 584-585.
Crossref
F. K. Gould. (2011) Linezolid: safety and efficacy in special populations. Journal of Antimicrobial Chemotherapy 66:Supplement 4, pages iv3-iv6.
Crossref
Megan Frantz, Sheila Wang & Nazha Abughali. (2011) Holocord Spinal Epidural Abscess From Community-Acquired Methicillin-Resistant Staphylococcus aureus. Infectious Diseases in Clinical Practice 19:1, pages 61-63.
Crossref
Douglas J. Biedenbach, David J. Farrell, Rodrigo E. Mendes, James E. Ross & Ronald N. Jones. (2010) Stability of linezolid activity in an era of mobile oxazolidinone resistance determinants: results from the 2009 Zyvox® Annual Appraisal of Potency and Spectrum program. Diagnostic Microbiology and Infectious Disease 68:4, pages 459-467.
Crossref
Theodosios Bisdas, Martin Bredt, Maximilian Pichlmaier, Thomas Aper, Mathias Wilhelmi, Sotirios Bisdas, Axel Haverich & Omke E. Teebken. (2010) Eight-year experience with cryopreserved arterial homografts for the in situ reconstruction of abdominal aortic infections. Journal of Vascular Surgery 52:2, pages 323-330.
Crossref
. (2010) Current awareness: Pharmacoepidemiology and drug safety. Pharmacoepidemiology and Drug Safety 19:8, pages i-xiii.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.