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Review Article

The importance of tissue penetration in achieving successful antimicrobial treatment of nosocomial pneumonia and complicated skin and soft-tissue infections caused by methicillin-resistant Staphylococcus aureus: vancomycin and linezolid

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Pages 571-588 | Accepted 26 Nov 2009, Published online: 08 Jan 2010

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Adrienne G Randolph, Ruifei Xu, Tanya Novak, Margaret M Newhams, Juliane Bubeck Wardenburg, Scott L Weiss, Ronald C Sanders, Neal J Thomas, Mark W Hall, Keiko M Tarquinio, Natalie Cvijanovich, Rainer G Gedeit, Edward J Truemper, Barry Markovitz, Mary E Hartman, Kate G Ackerman, John S GiulianoJrJr, Steven L Shein, Kristin L Moffitt, Michele Kong, Ronald C Sanders, Glenda Hefley, David Tellez, Katri Typpo, Barry Markovitz, Rica Sharon P Morzov, Ana Lia Graciano, Natalie Cvijanovich, Heidi Flori, Becky Brumfield, Nick Anas, Adam Schwarz, Ofelia Vargas-Shiraishi, Patrick McQuillen, Anil Sapru, Peter Mourani, Angela Czaja, Christopher Carroll, John S Giuliano, Joana Tala, Lisa Palmieri, Gwenn McLaughlin, Matthew Paden, Keiko Tarquinio, Cheryl L Stone, Bria M Coates, Neethi Pinto, Janice Sullivan, Vicki Montgomery, Adrienne G Randolph, Ruifei Xu, Anna A Agan, Tanya Novak, Margaret M Newhams, Melania Bembea, Sapna Kudchadkar, Stephen C Kurachek, Mary E Hartman, Allan Doctor, Tina Barrale, Edward J Truemper, Sidharth Mahapatra, Machelle Dawson, Lucinda Kustka, Kristin Malone, Melanie Schrack, Chhavi Katyal, Kate G Ackerman, L Eugene Daugherty, Steven L Shein, Eloise Lemon, Kathryn DeFrancesco, Mark W Hall, Lisa Steele, Neal Thomas, Debra Spear, Scott L Weiss, Julie Fitzgerald, Jenny L Bush, Kathryn Graham, Frederick E Barr, Renee Higgerson, LeeAnn Christie, Cindy Darnell Bowens, Marita Thompson, Laura L Loftis, Nancy Jaimon, Douglas F Wilson, Rainer G Gedeit, Kathy Murkowski, Katherine Siegel & Marc-André Dugas. (2019) Vancomycin Monotherapy May Be Insufficient to Treat Methicillin-resistant Staphylococcus aureus Coinfection in Children With Influenza-related Critical Illness . Clinical Infectious Diseases 68:3, pages 365-372.
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Crossref
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Crossref
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Sanjay K. Jain. 2017. Imaging Infections. Imaging Infections 1 15 .
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Fábio D. A. Gonçalves & Carla C. C. R. de Carvalho. (2016) Phenotypic Modifications in Staphylococcus aureus Cells Exposed to High Concentrations of Vancomycin and Teicoplanin. Frontiers in Microbiology 7.
Crossref
Santi M. Mandal, Ananta K. Ghosh & Bikas R. Pati. (2015) Dissemination of antibiotic resistance in methicillin-resistant Staphylococcus aureus and vancomycin-resistant S aureus strains isolated from hospital effluents. American Journal of Infection Control 43:12, pages e87-e88.
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C. Eckmann, D. Nathwani, W. Lawson, S. Corman, C. Solem, J. Stephens, C. Macahilig, J. Li, C. Charbonneau, N. Baillon-Plot & S. Haider. (2015) Comparison of vancomycin and linezolid in patients with peripheral vascular disease and/or diabetes in an observational European study of complicated skin and soft-tissue infections due to methicillin-resistant Staphylococcus aureus. Clinical Microbiology and Infection 21, pages S33-S39.
Crossref
Jian-Li Ma, Lei Gao, Xiang Li, Wan-Li Chu, Yong-Qiang Feng, Xiao-Qin Wang & Qing-Zhe Zhang. (2014) Comparison of the pharmacokinetics of linezolid in burn and non-burn rabbits. European Journal of Drug Metabolism and Pharmacokinetics 40:3, pages 355-361.
Crossref
T. Steinmetz, N. Eliakim-Raz, E. Goldberg, L. Leibovici & D. Yahav. (2015) Association of vancomycin serum concentrations with efficacy in patients with MRSA infections: a systematic review and meta-analysis. Clinical Microbiology and Infection 21:7, pages 665-673.
Crossref
Matthew Dryden, Arjana Tambic Andrasevic, Matteo Bassetti, Emilio Bouza, Jean Chastre, Mo Baguneid, Silvano Esposito, Helen Giamarellou, Inge Gyssens, Dilip Nathwani, Serhat Unal, Andreas Voss & Mark Wilcox. (2015) Managing skin and soft-tissue infection and nosocomial pneumonia caused by MRSA: a 2014 follow-up survey. International Journal of Antimicrobial Agents 45, pages S1-S14.
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P. Cojutti, N. Maximova, G. Crichiutti, M. Isola & F. Pea. (2014) Pharmacokinetic/pharmacodynamic evaluation of linezolid in hospitalized paediatric patients: a step toward dose optimization by means of therapeutic drug monitoring and Monte Carlo simulation. Journal of Antimicrobial Chemotherapy 70:1, pages 198-206.
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Shawn H. MacVane, Wonhee So, David P. Nicolau & Joseph L. Kuti. (2014) In Vitro Activity of Human-Simulated Epithelial Lining Fluid Exposures of Ceftaroline, Ceftriaxone, and Vancomycin against Methicillin-Susceptible and -Resistant Staphylococcus aureus . Antimicrobial Agents and Chemotherapy 58:12, pages 7520-7526.
Crossref
. (2014) An Evaluation of Sharp Cut Cyclones for Sampling Diesel Particulate Matter Aerosol in the Presence of Respirable Dust. The Annals of Occupational Hygiene.
Crossref
Ahmed Hamed Salem, George G Zhanel, Safaa A Ibrahim & Ayman M Noreddin. (2014) Monte Carlo simulation analysis of ceftobiprole, dalbavancin, daptomycin, tigecycline, linezolid and vancomycin pharmacodynamics against intensive care unit-isolated methicillin-resistant Staphylococcus aureus . Clinical and Experimental Pharmacology and Physiology 41:6, pages 437-443.
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N. Bourgeois-Nicolaos, T. T. Nguyen, G. Defrance, L. Massias, L. Alavoine, A Lefort, V. Noel, E. Senneville, F. Doucet-Populaire, F. Mentré, A. Andremont & X. Duval. (2014) The Emergence of Linezolid Resistance among Enterococci in Intestinal Microbiota of Treated Patients Is Unrelated to Individual Pharmacokinetic Characteristics. Antimicrobial Agents and Chemotherapy 58:5, pages 2681-2687.
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M. Bassetti, M. Baguneid, E. Bouza, M. Dryden, D. Nathwani & M. Wilcox. (2014) European perspective and update on the management of complicated skin and soft tissue infections due to methicillin-resistant Staphylococcus aureus after more than 10 years of experience with linezolid. Clinical Microbiology and Infection 20, pages 3-18.
Crossref
J. Chastre, F. Blasi, R.G. Masterton, J. Relio, A. Torres & T. Welte. (2014) European perspective and update on the management of nosocomial pneumonia due to methicillin-resistant Staphylococcus aureus after more than 10 years of experience with linezolid. Clinical Microbiology and Infection 20, pages 19-36.
Crossref
Theodor Tirilomis. (2014) Daptomycin and Its Immunomodulatory Effect: Consequences for Antibiotic Treatment of Methicillin-Resistant Staphylococcus aureus Wound Infections after Heart Surgery. Frontiers in Immunology 5.
Crossref
Jonathan D. FosterLauren A. TrepanierJennifer A. Ginn. (2014) Use of Linezolid to Treat MRSP Bacteremia and Discospondylitis in a Dog. Journal of the American Animal Hospital Association 50:1, pages 53-58.
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Laura A. Puzniak, Kimbal D. Ford & David B. Huang. (2014) The Prevalence of Methicillin-Resistant Staphylococcus aureus Colonization in Patients with Complicated Skin and Skin Structure Infections after Treatment with Linezolid or Vancomycin. Advances in Infectious Diseases 04:04, pages 186-193.
Crossref
Sangeetha Thirumazhisi Sachithanandam. (2014) Rising Methicillin-Resistant Staphylococcus aureus Infections in Ear, Nose, and Throat Diseases . Case Reports in Otolaryngology 2014, pages 1-3.
Crossref
Timothy Felton, Peter F. Troke & William W. Hope. (2014) Tissue Penetration of Antifungal Agents. Clinical Microbiology Reviews 27:1, pages 68-88.
Crossref
Ursula Theuretzbacher. 2014. Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics. Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics 401 443 .
L Galli, C Montagnani, E Chiappini & M de Martino. (2013) Treating paediatric community-acquired pneumonia in the era of antimicrobial resistance. Acta Paediatrica 102, pages 25-33.
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Laura A. Puzniak, Lee E. Morrow, David B. Huang & Jason N. Barreto. (2013) Impact of Weight on Treatment Efficacy and Safety in Complicated Skin and Skin Structure Infections and Nosocomial Pneumonia Caused by Methicillin-Resistant Staphylococcus aureus. Clinical Therapeutics 35:10, pages 1557-1570.
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Y. Nukui, S. Hatakeyama, K. Okamoto, T. Yamamoto, A. Hisaka, H. Suzuki, N. Yata, H. Yotsuyanagi & K. Moriya. (2013) High plasma linezolid concentration and impaired renal function affect development of linezolid-induced thrombocytopenia. Journal of Antimicrobial Chemotherapy 68:9, pages 2128-2133.
Crossref
Carina Vingsbo Lundberg & Niels Frimodt-Møller. (2013) Efficacy of topical and systemic antibiotic treatment of meticillin-resistant Staphylococcus aureus in a murine superficial skin wound infection model. International Journal of Antimicrobial Agents 42:3, pages 272-275.
Crossref
Simon Tremblay, Tim TY Lau & Mary HH Ensom. (2013) Addition of Rifampin to Vancomycin for Methicillin-Resistant Staphylococcus aureus Infections: What Is the Evidence? . Annals of Pharmacotherapy 47:7-8, pages 1045-1054.
Crossref
Katie M Muzevich & Kimberly B Lee. (2013) Subtherapeutic Linezolid Concentrations in a Patient with Morbid Obesity and Methicillin-Resistant Staphylococcus aureus Pneumonia: Case Report and Review of the Literature . Annals of Pharmacotherapy 47:6, pages e25-e25.
Crossref
Gregory J. Moran, Fredrick M. Abrahamian, Frank LoVecchio & David A. Talan. (2013) Acute Bacterial Skin Infections: Developments Since the 2005 Infectious Diseases Society of America (IDSA) Guidelines. The Journal of Emergency Medicine 44:6, pages e397-e412.
Crossref
Marisel Segarra-Newnham & Timothy J Church. (2012) Pharmacotherapy for Methicillin-Resistant Staphylococcus aureus Nosocomial Pneumonia. Annals of Pharmacotherapy 46:12, pages 1678-1687.
Crossref
Yasuhisa Abe, Katsumi Shigemura, Hiroyuki Yoshida, Masato Fujisawa & Soichi Arakawa. (2012) Risk factors for anti-MRSA drug resistance. International Journal of Antimicrobial Agents 40:5, pages 423-426.
Crossref
Koichi Toda, Yumiko Yonemoto, Tomoyuki Fujita, Yusuke Shimahara, Shyunsuke Sato, Takeshi Nakatani & Junjiro Kobayashi. (2012) Risk Analysis of Bloodstream Infection During Long-Term Left Ventricular Assist Device Support. The Annals of Thoracic Surgery 94:5, pages 1387-1393.
Crossref
Marco Falcone, Francesco Blasi, Francesco Menichetti, Federico Pea & Francesco Violi. (2012) Pneumonia in frail older patients: an up to date. Internal and Emergency Medicine 7:5, pages 415-424.
Crossref
F. Pea, P. Viale, P. Cojutti, B. Del Pin, E. Zamparini & M. Furlanut. (2012) Therapeutic drug monitoring may improve safety outcomes of long-term treatment with linezolid in adult patients. Journal of Antimicrobial Chemotherapy 67:8, pages 2034-2042.
Crossref
B Edwards & IM Gould. (2012) Meticillin-resistant Staphylococcus aureus pneumonia . British Journal of Hospital Medicine 73:7, pages 386-391.
Crossref
Therèse M. DuaneJohn A. WeigeltLaura A. PuzniakDavid B. Huang. (2012) Linezolid and Vancomycin in Treatment of Lower-Extremity Complicated Skin and Skin Structure Infections Caused by Methicillin-Resistant Staphylococcus aureus in Patients with and without Vascular Disease . Surgical Infections 13:3, pages 147-153.
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Pamela R. Tessier, Rebecca A. Keel, Mao Hagihara, Jared L. Crandon & David P. Nicolau. (2012) Comparative In Vivo Efficacies of Epithelial Lining Fluid Exposures of Tedizolid, Linezolid, and Vancomycin for Methicillin-Resistant Staphylococcus aureus in a Mouse Pneumonia Model . Antimicrobial Agents and Chemotherapy 56:5, pages 2342-2346.
Crossref
Karen L. Leach, Steven J. Brickner, Mark C. Noe & Paul F. Miller. (2011) Linezolid, the first oxazolidinone antibacterial agent. Annals of the New York Academy of Sciences 1222:1, pages 49-54.
Crossref
Marta Ulldemolins, Xavier Nuvials, Mercedes Palomar, Joan R. Masclans & Jordi Rello. (2011) Appropriateness is Critical. Critical Care Clinics 27:1, pages 35-51.
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Chikara Sakai & Hiroaki Soda. (2011) Severe ventilator-associated pneumonia caused by methicillin-resistant Staphylococcus aureus and other pathogens: report of a case successfully managed by serial surveillance cultures of endotracheal aspirates. Journal of Infection and Chemotherapy 17:3, pages 424-428.
Crossref
Federico Pea, Mario Furlanut, Piergiorgio Cojutti, Francesco Cristini, Eleonora Zamparini, Loretta Franceschi & Pierluigi Viale. (2010) Therapeutic Drug Monitoring of Linezolid: a Retrospective Monocentric Analysis. Antimicrobial Agents and Chemotherapy 54:11, pages 4605-4610.
Crossref
Carlos M. Luna, Didier Bruno & Patricia Aruj. (2010) Vancomycin, unbeatable for methicillin-resistant Staphylococcus aureus hospital-acquired pneumonia? Really?*. Critical Care Medicine 38:9, pages 1910-1912.
Crossref

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