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Original Article

Add-back therapy use and its impact on LA persistence in patients with endometriosis

, , , &
Pages 729-736 | Accepted 28 Dec 2009, Published online: 21 Jan 2010

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Ahmed M. Soliman, Machaon Bonafede, Amanda M. Farr, Jane Castelli-Haley & Craig Winkel. (2016) Analysis of subsequent surgery rates among endometriosis patients who underwent surgery with and without concomitant leuprolide acetate therapy. Current Medical Research and Opinion 32:6, pages 1073-1082.
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David L Olive. (2011) GnRH agonist therapy and the use of sex steroid add-back: improving the product. Expert Review of Obstetrics & Gynecology 6:6, pages 583-585.
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Daniel Alexander Beyer, Feriel Amari, Marc Thill, Askan Schultze-Mosgau, Safaa Al-Hasani, Klaus Diedrich & Georg Griesinger. (2011) Emerging gonadotropin-releasing hormone agonists. Expert Opinion on Emerging Drugs 16:2, pages 323-340.
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Articles from other publishers (16)

Eric S. Surrey. (2023) GnRH agonists in the treatment of symptomatic endometriosis: a review. F&S Reports 4:2, pages 40-45.
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O.A. Pustotina. (2023) Agonists of gonadotropin-releasing-hormone and add-back-therapy. Rossiiskii vestnik akushera-ginekologa 23:2, pages 63.
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Zhenyue Qin, Zhiyong Dong, Junling Liu, Ahong Zhong, Mingyue Bao, Huihui Wang, Hongxia Yu, Shoufeng Zhang, Wendi Zhang, Li Shen, Jie Wu & Jiming Chen. (2022) A Preliminary Study on the Effects of Black Cohosh Preparations on Bone Metabolism of Rat Models With GnRH-a-Induced Peri-Menopausal Symptoms. Frontiers in Endocrinology 13.
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May-Tal Sauerbrun-Cutler & Ruben Alvero. (2019) Short- and long-term impact of gonadotropin-releasing hormone analogue treatment on bone loss and fracture. Fertility and Sterility 112:5, pages 799-803.
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Thomas D’Hooghe, Takao Fukaya, Yutaka Osuga, Robin Besuyen, Beatriz López, Gertjan M Holtkamp, Kentaro Miyazaki & Laurence Skillern. (2019) Efficacy and safety of ASP1707 for endometriosis-associated pelvic pain: the phase II randomized controlled TERRA study. Human Reproduction 34:5, pages 813-823.
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N. K. Akhkubekova, A. S. Kaysinova, A. A. Fedorov, N. B. Efimenko, I. I. Gaidamaka, E. N. Chalaja, L. A. Cherevashchenko, L. V. Tsallagova, E. E. Urvacheva & A. B. Ovsienko. (2018) The role of the combined balneotherapeutic treatment as the 'add-back therapy' against the background of the anti-hormonal effects of the agonists of gonadotropin-releasing hormone in the women suffering from endometriosis genitalis externa. Voprosy kurortologii, fizioterapii i lechebnoi fizicheskoi kul'tury 95:5, pages 31.
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Ahmed M. Soliman, Machaon Bonafede, Amanda M. Farr, Jane Castelli-Haley & Craig Winkel. (2016) Analysis of Adherence, Persistence, and Surgery Among Endometriosis Patients Treated with Leuprolide Acetate Plus Norethindrone Acetate Add-Back Therapy. Journal of Managed Care & Specialty Pharmacy 22:5, pages 573-587.
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Hsiao-Wen Tsai, Peng-Hui Wang, Ben-Shian Huang, Nae-Fang Twu, Ming-Shyen Yen & Yi-Jen Chen. (2016) Low-dose add-back therapy during postoperative GnRH agonist treatment. Taiwanese Journal of Obstetrics and Gynecology 55:1, pages 55-59.
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Michael P. Diamond, Bruce Carr, W. Paul Dmowski, William Koltun, Chris O’Brien, Ping Jiang, Joshua Burke, Roland Jimenez, Elizabeth Garner & Kristof Chwalisz. (2014) Elagolix Treatment for Endometriosis-Associated Pain: Results from a Phase 2, Randomized, Double-Blind, Placebo-Controlled Study. Reproductive Sciences 21:3, pages 363-371.
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Amy D. DiVasta & Marc R. Laufer. (2013) The use of gonadotropin releasing hormone analogues in adolescent and young patients with endometriosis. Current Opinion in Obstetrics & Gynecology 25:4, pages 287-292.
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Bruce Carr, Linda Giudice, W. Paul Dmowski, Chris O'Brien, Ping Jiang, Joshua Burke, Roland Jimenez, Steven Hass, Mahesh Fuldeore & Kristof Chwalisz. (2013) Elagolix, an Oral GnRH Antagonist for Endometriosis-Associated Pain: A Randomized Controlled Study. Journal of Endometriosis and Pelvic Pain Disorders 5:3, pages 105-115.
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Kristof Chwalisz, Eric Surrey & Frank Z. Stanczyk. (2012) The Hormonal Profile of Norethindrone Acetate: Rationale for Add-Back Therapy With Gonadotropin-Releasing Hormone Agonists in Women With Endometriosis. Reproductive Sciences 19:6, pages 563-571.
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Jong Kil JooIn Kook JungKi Hyung KimKyu Sup Lee. (2012) Quality of life according to add-back therapy during GnRH agonist treatment in endometriosis patients. Korean Journal of Obstetrics & Gynecology 55:6, pages 371.
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Tommaso Falcone & Dan I. Lebovic. (2011) Clinical Management of Endometriosis. Obstetrics & Gynecology 118:3, pages 691-705.
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. (2010) Current World Literature. Current Opinion in Obstetrics & Gynecology 22:4, pages 354-359.
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Eric S Surrey. (2010) Gonadotropin-releasing hormone agonist and add-back therapy: what do the data show?. Current Opinion in Obstetrics & Gynecology 22:4, pages 283-288.
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